Keratinocyte growth factor administration attenuates murine pulmonary Mycobacterium tuberculosis infection through granulocyte-macrophage colony-stimulating factor (GM-CSF)-dependent macrophage activation and phagolysosome fusion

Journal of Biological Chemistry

Volumn 290, Issue 11, 2015, Pages 7151-7159

  Pasula, Rajamouli ^a   Azad, Abul K ^b   Gardner, Jason C ^a   Schlesinger, Larry S ^b   McCormack, Francis X ^a  

^a UNIVERSITY OF CINCINNATI COLLEGE OF MEDICINE   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MAMMALS; NITRIC OXIDE;

ALVEOLAR MACROPHAGES; CONDITIONED MEDIUM; DRUG-RESISTANT STRAINS; GRANULOCYTE-MACROPHAGE COLONY STIMULATING FACTORS; KERATINOCYTE GROWTH FACTORS; M. TUBERCULOSIS; MACROPHAGE ACTIVATION; MYCOBACTERIUM TUBERCULOSIS;

MACROPHAGES;

GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; KERATINOCYTE GROWTH FACTOR; NITRIC OXIDE; TUBERCULOSTATIC AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL CLEARANCE; BACTERIAL GROWTH; CELL FUSION; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESPONSE; FEMALE; IN VITRO STUDY; INFECTION PREVENTION; LUNG ALVEOLUS MACROPHAGE; LUNG TUBERCULOSIS; MACROPHAGE ACTIVATION; MORTALITY; MOUSE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOLYSOSOME; PHAGOLYSOSOME FUSION; PRIORITY JOURNAL; WEIGHT REDUCTION; ANIMAL; C57BL MOUSE; CELL CULTURE; DRUG EFFECTS; IMMUNOLOGY; LUNG; MACROPHAGE; MICROBIOLOGY; PHAGOSOME; TUBERCULOSIS, PULMONARY;

BACILLI (CLASS); MURINAE; MUS; MYCOBACTERIUM TUBERCULOSIS;

ANIMALS; ANTITUBERCULAR AGENTS; CELLS, CULTURED; FEMALE; FIBROBLAST GROWTH FACTOR 7; GRANULOCYTE-MACROPHAGE COLONY-STIMULATING FACTOR; LUNG; MACROPHAGE ACTIVATION; MACROPHAGES; MICE; MICE, INBRED C57BL; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOMES; TUBERCULOSIS, PULMONARY;

EID: 84924911796     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.591891     Document Type: Article

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