The oncogenic microRNA-21 inhibits the tumor suppressive activity of FBXO11 to promote tumorigenesis

Journal of Biological Chemistry

Volumn 290, Issue 10, 2015, Pages 6037-6046

  Yang, Chuan He ^a   Pfeffer, Susan R ^a   Sims, Michelle ^a   Yue, Junming ^a   Wang, Yinan ^a   Linga, Vijay G ^a   Paulus, Elena ^a   Davidoff, Andrew M ^a,b   Pfeffer, Lawrence M ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

^b ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL DEATH; DISEASES; GENES; POLYMERASE CHAIN REACTION; PROTEINS; RNA; TUMORS;

MICROARRAY ANALYSIS; ONCOGENIC ACTIVITIES; ONCOGENIC PROTEINS; PATIENT SURVIVALS; PROTEOSOMAL DEGRADATION; TUMOR SUPPRESSOR ACTIVITY; TUMOR SUPPRESSORS; UBIQUITIN LIGASES;

GENE EXPRESSION;

F BOX PROTEIN; FBXO11 F BOX PROTEIN; MICRORNA 21; PROTEIN BCL 6; UNCLASSIFIED DRUG; FBXO11 PROTEIN, HUMAN; MICRORNA; MIRN21 MICRORNA, HUMAN; PROTEIN ARGININE METHYLTRANSFERASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER GRADING; CANCER INHIBITION; CANCER SURVIVAL; CARCINOGENESIS; CARCINOGENICITY; CONTROLLED STUDY; DOWN REGULATION; GAIN OF FUNCTION MUTATION; GENE EXPRESSION; GENE SILENCING; GENE TARGETING; GLIOBLASTOMA; HUMAN; HUMAN CELL; HUMAN TISSUE; LOSS OF FUNCTION MUTATION; MALE; MELANOMA; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN TARGETING; QUANTITATIVE ANALYSIS; ANIMAL; BIOSYNTHESIS; CELL PROLIFERATION; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOLECULARLY TARGETED THERAPY; PATHOLOGY; PROSTATE TUMOR;

ANIMALS; APOPTOSIS; CARCINOGENESIS; CELL PROLIFERATION; F-BOX PROTEINS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLIOBLASTOMA; HUMANS; MALE; MELANOMA; MICE; MICRORNAS; MOLECULAR TARGETED THERAPY; PROSTATIC NEOPLASMS; PROTEIN-ARGININE N-METHYLTRANSFERASES;

EID: 84924873137     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.632125     Document Type: Article

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