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Volumn 110, Issue 6, 2007, Pages 2067-2074

BCL6 programs lymphoma cells for survival and differentiation through distinct biochemical mechanisms

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM BINDING PROTEIN; NUCLEAR RECEPTOR COREPRESSOR; PROTEIN BCL 6; PROTEIN MTS3; PROTEIN PRDM1; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

EID: 34548256410     PISSN: 00064971     EISSN: 00064971     Source Type: Journal    
DOI: 10.1182/blood-2007-01-069575     Document Type: Article
Times cited : (120)

References (33)
  • 1
    • 0027495491 scopus 로고
    • Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma
    • Ye BH, Lista F, Lo Coco F, et al. Alterations of a zinc finger-encoding gene, BCL-6, in diffuse large-cell lymphoma. Science. 1993;262:747-750.
    • (1993) Science , vol.262 , pp. 747-750
    • Ye, B.H.1    Lista, F.2    Lo Coco, F.3
  • 2
    • 0037069331 scopus 로고    scopus 로고
    • Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas
    • Wang X, Li Z, Naganuma A, Ye BH. Negative autoregulation of BCL-6 is bypassed by genetic alterations in diffuse large B cell lymphomas. Proc Natl Acad Sci U S A. 2002;99:15018-15023.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 15018-15023
    • Wang, X.1    Li, Z.2    Naganuma, A.3    Ye, B.H.4
  • 3
    • 0030901289 scopus 로고    scopus 로고
    • Control of inflammation, cytokine expression, and germinal center formation by BCL-6
    • Dent AL, Shaffer AL, Yu X, Allman D, Staudt LM. Control of inflammation, cytokine expression, and germinal center formation by BCL-6. Science. 1997;276:589-592.
    • (1997) Science , vol.276 , pp. 589-592
    • Dent, A.L.1    Shaffer, A.L.2    Yu, X.3    Allman, D.4    Staudt, L.M.5
  • 4
    • 17144439800 scopus 로고    scopus 로고
    • The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation
    • Ye BH, Cattoretti G, Shen Q, et al. The BCL-6 proto-oncogene controls germinal-centre formation and Th2-type inflammation. Nat Genet. 1997;16:161-170.
    • (1997) Nat Genet , vol.16 , pp. 161-170
    • Ye, B.H.1    Cattoretti, G.2    Shen, Q.3
  • 5
    • 34250762588 scopus 로고    scopus 로고
    • Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR
    • Ranuncolo SM, Polo JM, Dierov J, et al. Bcl-6 mediates the germinal center B cell phenotype and lymphomagenesis through transcriptional repression of the DNA-damage sensor ATR. Nat Immunol. 2007;8:705-714.
    • (2007) Nat Immunol , vol.8 , pp. 705-714
    • Ranuncolo, S.M.1    Polo, J.M.2    Dierov, J.3
  • 6
    • 10344247666 scopus 로고    scopus 로고
    • The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells
    • Phan RT, Dalla-Favera R. The BCL6 proto-oncogene suppresses p53 expression in germinal-centre B cells. Nature. 2004;432:635-639.
    • (2004) Nature , vol.432 , pp. 635-639
    • Phan, R.T.1    Dalla-Favera, R.2
  • 7
    • 27144462049 scopus 로고    scopus 로고
    • BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells
    • Phan RT, Saito M, Basso K, Niu H, Dalla-Favera R. BCL6 interacts with the transcription factor Miz-1 to suppress the cyclin-dependent kinase inhibitor p21 and cell cycle arrest in germinal center B cells. Nat Immunol. 2005;6:1054-1060.
    • (2005) Nat Immunol , vol.6 , pp. 1054-1060
    • Phan, R.T.1    Saito, M.2    Basso, K.3    Niu, H.4    Dalla-Favera, R.5
  • 8
    • 33847674920 scopus 로고    scopus 로고
    • A transcriptional signature with differential expression of BCL6 target genes identifies BCL6-dependent diffuse large B-cell lymphomas
    • Polo J, Juszczynski P, Monti S, et al. A transcriptional signature with differential expression of BCL6 target genes identifies BCL6-dependent diffuse large B-cell lymphomas. Proc Natl Acad Sci U S A. 2007;104:3207-3212.
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3207-3212
    • Polo, J.1    Juszczynski, P.2    Monti, S.3
  • 9
    • 0033680860 scopus 로고    scopus 로고
    • BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control
    • Shaffer AL, Yu X, He Y, Boldrick J, Chan EP, Staudt LM. BCL-6 represses genes that function in lymphocyte differentiation, inflammation, and cell cycle control. Immunity. 2000;13:199-212.
    • (2000) Immunity , vol.13 , pp. 199-212
    • Shaffer, A.L.1    Yu, X.2    He, Y.3    Boldrick, J.4    Chan, E.P.5    Staudt, L.M.6
  • 11
    • 0037103133 scopus 로고    scopus 로고
    • Repression of AP-1 function: A mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene
    • Vasanwala FH, Kusam S, Toney LM, Dent AL. Repression of AP-1 function: a mechanism for the regulation of Blimp-1 expression and B lymphocyte differentiation by the B cell lymphoma-6 protooncogene. J Immunol. 2002;169:1922-1929.
    • (2002) J Immunol , vol.169 , pp. 1922-1929
    • Vasanwala, F.H.1    Kusam, S.2    Toney, L.M.3    Dent, A.L.4
  • 12
    • 0037998827 scopus 로고    scopus 로고
    • Transcriptional regulatory cascades controlling plasma cell differentiation
    • Lin KI, Tunyaplin C, Calame K. Transcriptional regulatory cascades controlling plasma cell differentiation. Immunol Rev. 2003;194:19-28.
    • (2003) Immunol Rev , vol.194 , pp. 19-28
    • Lin, K.I.1    Tunyaplin, C.2    Calame, K.3
  • 13
    • 0032511890 scopus 로고    scopus 로고
    • The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT
    • Huynh KD, Bardwell VJ. The BCL-6 POZ domain and other POZ domains interact with the co-repressors N-CoR and SMRT. Oncogene. 1998;17:2473-2484.
    • (1998) Oncogene , vol.17 , pp. 2473-2484
    • Huynh, K.D.1    Bardwell, V.J.2
  • 14
    • 0034661112 scopus 로고    scopus 로고
    • Huynh KD, Fischle W, Verdin E, Bardwell VJ. BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev. 2000;14:1810-1823.
    • Huynh KD, Fischle W, Verdin E, Bardwell VJ. BCoR, a novel corepressor involved in BCL-6 repression. Genes Dev. 2000;14:1810-1823.
  • 15
    • 9144242434 scopus 로고    scopus 로고
    • Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain
    • Ahmad KF, Melnick A, Lax S, et al. Mechanism of SMRT corepressor recruitment by the BCL6 BTB domain. Mol Cell. 2003;12:1551-1564.
    • (2003) Mol Cell , vol.12 , pp. 1551-1564
    • Ahmad, K.F.1    Melnick, A.2    Lax, S.3
  • 16
    • 11144277489 scopus 로고    scopus 로고
    • Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells
    • Polo JM, Dell'Oso T, Ranuncolo SM, et al. Specific peptide interference reveals BCL6 transcriptional and oncogenic mechanisms in B-cell lymphoma cells. Nat Med. 2004;10:1329-1335.
    • (2004) Nat Med , vol.10 , pp. 1329-1335
    • Polo, J.M.1    Dell'Oso, T.2    Ranuncolo, S.M.3
  • 17
    • 5344280456 scopus 로고    scopus 로고
    • MTA3 and Mi-2/NuRD complex regulate cell fate during B-lymphocyte differentiation
    • Fujita N, Jaye DL, Geigerman C, et al. MTA3 and Mi-2/NuRD complex regulate cell fate during B-lymphocyte differentiation. Cell. 2004;119:75-86.
    • (2004) Cell , vol.119 , pp. 75-86
    • Fujita, N.1    Jaye, D.L.2    Geigerman, C.3
  • 18
    • 0344953578 scopus 로고    scopus 로고
    • Transcriptional analysis of the B cell germinal center reaction
    • Klein U, Tu Y, Stolovitzky GA, et al. Transcriptional analysis of the B cell germinal center reaction. Proc Natl Acad Sci U S A. 2003;100:2639-2644.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2639-2644
    • Klein, U.1    Tu, Y.2    Stolovitzky, G.A.3
  • 19
    • 33745848147 scopus 로고    scopus 로고
    • BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate
    • Juszczynski P, Kutok JL, Li C, Mitra J, Aguiar RC, Shipp MA. BAL1 and BBAP are regulated by a gamma interferon-responsive bidirectional promoter and are overexpressed in diffuse large B-cell lymphomas with a prominent inflammatory infiltrate. Mol Cell Biol. 2006;26:5348-5359.
    • (2006) Mol Cell Biol , vol.26 , pp. 5348-5359
    • Juszczynski, P.1    Kutok, J.L.2    Li, C.3    Mitra, J.4    Aguiar, R.C.5    Shipp, M.A.6
  • 20
    • 20144382754 scopus 로고    scopus 로고
    • Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response
    • Monti S, Savage KJ, Kutok JL, et al. Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response. Blood. 2005;105:1851-1861.
    • (2005) Blood , vol.105 , pp. 1851-1861
    • Monti, S.1    Savage, K.J.2    Kutok, J.L.3
  • 22
    • 0029045421 scopus 로고
    • BCL-6 protein is expressed in germinal-center B cells
    • Cattoretti G, Chang CC, Cechova K, et al. BCL-6 protein is expressed in germinal-center B cells. Blood. 1995;86:45-53.
    • (1995) Blood , vol.86 , pp. 45-53
    • Cattoretti, G.1    Chang, C.C.2    Cechova, K.3
  • 23
    • 0036768382 scopus 로고    scopus 로고
    • The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development
    • Chang DH, Cattoretti G, Calame KL. The dynamic expression pattern of B lymphocyte induced maturation protein-1 (Blimp-1) during mouse embryonic development. Mech Dev. 2002;117:305-309.
    • (2002) Mech Dev , vol.117 , pp. 305-309
    • Chang, D.H.1    Cattoretti, G.2    Calame, K.L.3
  • 24
    • 10744220125 scopus 로고    scopus 로고
    • Relationship between REL amplification, REL function, and clinical and biologic features in diffuse large B-cell lymphomas
    • Houldsworth J, Olshen AB, Cattoretti G, et al. Relationship between REL amplification, REL function, and clinical and biologic features in diffuse large B-cell lymphomas. Blood. 2004;103:1862-1868.
    • (2004) Blood , vol.103 , pp. 1862-1868
    • Houldsworth, J.1    Olshen, A.B.2    Cattoretti, G.3
  • 26
    • 0034598746 scopus 로고    scopus 로고
    • Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling
    • Alizadeh AA, Eisen MB, Davis RE, et al. Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature. 2000;403:503-511.
    • (2000) Nature , vol.403 , pp. 503-511
    • Alizadeh, A.A.1    Eisen, M.B.2    Davis, R.E.3
  • 27
    • 0037142053 scopus 로고    scopus 로고
    • The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma
    • Rosenwald A, Wright G, Chan WC, et al. The use of molecular profiling to predict survival after chemotherapy for diffuse large-B-cell lymphoma. N Engl J Med. 2002;346:1937-1947.
    • (2002) N Engl J Med , vol.346 , pp. 1937-1947
    • Rosenwald, A.1    Wright, G.2    Chan, W.C.3
  • 28
    • 34548860800 scopus 로고    scopus 로고
    • BCL6, p53 and molecular targeted therapy in B-cell lymphomas
    • Abstract 1484
    • Cerchietti L, Polo J, DaSilva G, et al. BCL6, p53 and molecular targeted therapy in B-cell lymphomas. Blood. 2005;106: Abstract 1484.
    • (2005) Blood , pp. 106
    • Cerchietti, L.1    Polo, J.2    DaSilva, G.3
  • 29
    • 21244481727 scopus 로고    scopus 로고
    • The theoretical basis of transcriptional therapy of cancer: Can it be put into practice?
    • Melnick AM, Adelson K, Licht JD. The theoretical basis of transcriptional therapy of cancer: can it be put into practice? J Clin Oncol. 2005;23:3957-3970.
    • (2005) J Clin Oncol , vol.23 , pp. 3957-3970
    • Melnick, A.M.1    Adelson, K.2    Licht, J.D.3
  • 30
    • 0842285672 scopus 로고    scopus 로고
    • ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein
    • Chevallier N, Corcoran CM, Lennon C, et al. ETO protein of t(8;21) AML is a corepressor for Bcl-6 B-cell lymphoma oncoprotein. Blood. 2004;103:1454-1463.
    • (2004) Blood , vol.103 , pp. 1454-1463
    • Chevallier, N.1    Corcoran, C.M.2    Lennon, C.3
  • 32
    • 0033561797 scopus 로고    scopus 로고
    • Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia
    • Melnick A, Licht JD. Deconstructing a disease: RARalpha, its fusion partners, and their roles in the pathogenesis of acute promyelocytic leukemia. Blood. 1999;93:3167-3215.
    • (1999) Blood , vol.93 , pp. 3167-3215
    • Melnick, A.1    Licht, J.D.2
  • 33
    • 0036464594 scopus 로고    scopus 로고
    • Acute promyelocytic leukemia: Evolving therapeutic strategies
    • Tallman MS, Nabhan C, Feusner JH, Rowe JM. Acute promyelocytic leukemia: evolving therapeutic strategies. Blood. 2002;99:759-767.
    • (2002) Blood , vol.99 , pp. 759-767
    • Tallman, M.S.1    Nabhan, C.2    Feusner, J.H.3    Rowe, J.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.