Zinc sulphate and vitamin E alleviate reproductive toxicity caused by aluminium sulphate in male albino rats

Toxicology and Industrial Health

Volumn 31, Issue 3, 2015, Pages 221-234

  Rawi, Sayed M ^a   Seif al Nassr, Fatma M ^b  

^a KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^b CAIRO UNIVERSITY   (Egypt)

Author keywords

Aluminium sulphate; male albino rats; reproductive toxicity; vitamin E; zinc sulphate

Indexed keywords

ALPHA TOCOPHEROL; ALUMINUM POTASSIUM SULFATE; ALUMINUM SULFATE; ANTIOXIDANT; FOLLITROPIN; LUTEINIZING HORMONE; PROLACTIN; PROTECTIVE AGENT; TESTOSTERONE; ZINC SULFATE; CHOLESTEROL; LIPID; PHOSPHOLIPID; PROTEIN; TRIACYLGLYCEROL;

ANIMAL; BLOOD; DISEASE MODEL; DOSE RESPONSE; DRUG ADMINISTRATION; DRUG COMBINATION; DRUG EFFECTS; MALE; ORAL DRUG ADMINISTRATION; ORGAN SIZE; PATHOLOGY; RAT; TESTIS; ALUMINUM BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; CELL VACUOLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; FOLLITROPIN BLOOD LEVEL; HISTOPATHOLOGY; LIPID BLOOD LEVEL; NONHUMAN; PHOSPHOLIPID BLOOD LEVEL; PROLACTIN BLOOD LEVEL; PROTEIN BLOOD LEVEL; REPRODUCTIVE TOXICITY; SEMINIFEROUS TUBULE; SPERMATOCYTE; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; TRIACYLGLYCEROL BLOOD LEVEL; WEIGHT GAIN;

ADMINISTRATION, ORAL; ALUM COMPOUNDS; ANIMALS; ANTIOXIDANTS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; FOLLICLE STIMULATING HORMONE; LUTEINIZING HORMONE; MALE; ORGAN SIZE; PROLACTIN; PROTECTIVE AGENTS; RATS; TESTIS; TESTOSTERONE; VITAMIN E; ZINC SULFATE;

ANIMALIA; RATTUS;

EID: 84924861010     PISSN: 07482337     EISSN: 14770393     Source Type: Journal    
DOI: 10.1177/0748233712469650     Document Type: Article

References (74)

1. Akazawa N, Mikami S, Kimura S (1987) Effects of vitamin E deficiency on the hormone secretion of the pituitary–gonadal axis of the rat. Tohoku Journal of Experimental Medicine 152(3): 221–229.
2. Akinsanya MA, Adeniyi TT, Ajayi GO, Oyedele MA (2010) Effects of vitamin E and folic acid on some antioxidant enzymes activities of female Wistar rats administered combined oral contraceptives. African Journal of Biochemistry Research 4(10): 238–242.
3. Albendea CD, Gómez-Trullén EM, Fuentes-Broto L, Miana-Mena FJ, Millán-Plano S, Reyes-Gonzales MC et al. (2007) Melatonin reduces lipid and protein oxidative damage in synaptosomes due to aluminium. Journal of Trace Elements in Medicine and Biology 21(4): 261–268.
4. Allian CC (1974) Enzymatic determination of cholesterol. Clinical Chemistry 20: 470–475.
5. Banchraft JD, Stevens A, Turner DR (1996) Theory and Practice of Histological Techniques. 4th ed. New York, San Francisco, London, Tokyo: Churchill Livingstone.
6. Bedwal RS, Bahuguna A (1994) Zinc, copper and selenium in reproduction. Experientia 50(7): 626–640.
7. Buraimoh AA, Ojo SA, Hambolu JO, Adebisi SS (2012) Histological study of the effect of aluminium chloride exposure on the testis of Wistar rats. American International Journal of Contemporary Research 2(5): 114–122.
8. Canadian Council on Animal Care (CCAC) (1993) Guide to the Care and Use of Experimental Animals. Vol. 2. Ottawa, Ontario, Canada: CCAC.
9. Chen TJ, Hung HS, Wang DC, Chen SS (2010) The protective effect of Rho-associated kinase inhibitor on aluminium-induced neurotoxicity in rat cortical neurons. Toxicological Sciences 116(1): 264–272.
10. Chia SE, Ong CN, Chua LH, Ho LM, Tay SK (2000) Comparison of zinc concentrations in blood and seminal plasma and the various sperm parameters between fertile and infertile men. Journal of Andrology 21(1): 53–57.
11. Colagar AH, Marzony ET, Chaichi MJ (2009) Zinc levels in seminal plasma are associated with sperm quality in fertile and infertile men. Nutrition Research 29(2): 82–88.
12. Cunnane SC (1988) Role of zinc in lipid and fatty acid metabolism and in membranes. Progress in Food and Nutrition Science 12(2): 151–188.
13. Cyrill VS, Kunjan RD, Surendra SK (1999) Effect of aluminium-induced Alzheimer like condition on oxidative energy metabolism in rat liver, brain and heart mitochondria. Mechanisms of Ageing and Development 112(1): 27–42.
14. Domingo JL (1995) Reproductive and developmental toxicity of aluminium. A review. Neurotoxicology and Teratology 17(4): 515–521.
15. Ebisch IM, Van Heerde WL, Thomas CM, Vander Put N, Wong WY (2003) C677T methylene tetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration. Fertility and Sterility 80: 1190–1194.
16. Ebisch IM, Pierik FH, DE Jong FH, Thomas CM, Steegers Theunissen RP (2006) Does folic acid and zinc sulphate intervention affect endocrine parameters and sperm characteristics in men? International Journal of Andrology 29(2): 339–345.
17. Eggert-Kruse W, Zwick EM, Batschulat K, Rohr G, Armbruster FP, Petzoldt D et al. (2002) Are zinc levels in seminal plasma associated with seminal leukocytes and other determinants of semen quality? Fertility and Sterility 77(2): 260–269.
18. El-Ashmawy IM, Saleh A, Salama OM (2007) Effects of marjoram volatile oil and grape seed extract on ethanol toxicity in male rats. Basic and Clinical Pharmacology and Toxicology 101(5): 320–327.
19. El-Demerdash FM (2004) Antioxidant effect of vitamin E and selenium on lipid peroxidation, enzyme activities and biochemical parameters in rats exposed to aluminium. Journal of Trace Elements in Medicine and Biology 18(1): 113–121.
20. EL-Kholy WM, EL-Habibi EM, Mousa AT (2010) Oxidative stress in brains of male rats intoxicated with aluminium and the neuromodulating effect of some forms of sage (Salvia officinalis). Journal of American Science 6(12): 1283–1297.
21. El-Masry K, Alnasr AS, Kamal TH (1994) Influences of season and dietary supplementation with selenium and vitamin E or zinc on some blood constituents and semen quality of New Zealand white rabbits males. World Rabbit Science 2: 79–86.
22. Farina M, Roha LN, Soares FA, Jardim F, Jacques R, Souza DO et al. (2005) Hematological changes in rats chronically exposed to oral aluminium. Toxicology 209(1): 29–37.
23. Fortes C, Agabiti N, Fano V, Pacifici R, Forastiere F, Virgili F et al. (1997) Zinc supplementation and plasma lipid peroxides in an elderly population. European Journal of Clinical Nutrition 51(2): 97–101.
24. Fossati P, Prencipe L (1982) Serum triglycerides determined colorimetrically with an enzyme that produces hydrogen peroxide. Clinical Chemistry 28(10): 2077–2080.
25. Gorsky JE, Dietz AA (1978) Determination of aluminium in biological samples by atomic absorption spectrophotometry with a graphite furnace. Clinical Chemistry 24: 1485–1490.
26. Guo C, Lu Y, Hsu GSW (2005a) The influence of aluminium exposure on male reproduction and offspring in mice. Environmental Toxicology and Pharmacology 20: 135–141.
27. Gura KM (2010) Aluminium contamination in products used in parenteral nutrition: has anything changed? Nutrition 26(6): 585–594.
28. Hamdi SA, Nassif OI, Ardawi MS (1997) Effect of marginal or severe dietary zinc deficiency on testicular development and functions of the rat. Andrologia 38 (3): 243–253.
29. Herrera E, Barbas C (2001) Vitamin E: action, metabolism and perspectives. Journal of Physiology and Biochemistry 57(2): 43–56.
30. Holdunia P, Walter C (1992) Clinical evaluation of a direct radioimmuno assay of testosterone. Clinical Chemistry 214: 31–43.
31. Jacquillet G, Barbier O, Cougnon M, Tauc M, Namorado MC, Martin D et al. (2006) Zinc protects renal function during cadmium intoxication in the rat. American Journal of Physiology. Renal Physiology 290(1): 127–137.
32. Jenner A, Ren M, Rajendran R, Ning P, Huat BT, Watt F et al. (2007) Zinc supplementation inhibits lipid peroxidation and the development of atherosclerosis in rabbits fed a high cholesterol diet. Free Radical Biology and Medicine 42(4): 559–566.
33. Julka D, Gill KD (1996) Altered calcium homeostasis: a possible mechanism of aluminium-induced neurotoxicity. Biochimica Biophysica Acta 1315(1): 47–54.
34. Kendall NR, McMullan S, Green A, Rodway RG (2000) The effect of zinc, cobalt and selenium soluble glass bolus on trace element status and semen quality of ram lambs. Animal Reproduction Science 62(4): 277–283.
35. Khattab HAM, Abdallaha IZA, Kamel GM (2010) Grape seed extract alleviate reproductive toxicity caused by aluminium chloride in male rats. Journal of American Sciences 6(12): 1200–1209.
36. Kumar V, Bal A, Gill KD (2009a) Susceptibility of mitochondrial superoxide dismutase to aluminium induced oxidative damage. Toxicology 255(3): 117–123.
37. Kumar V, Bal A, Gill KD (2009b) Aluminium-induced oxidative DNA damage recognition and cell-cycle disruption in different regions of rat brain. Toxicology 264(3): 137–144.
38. Kutlubay R, Oguz EO, Can B, Guven MC, Sinik Z, Tuncay OL (2007) Vitamin E protection from testicular damage caused by intraperitoneal aluminium. International Journal of Toxicology 26(4): 297–306.
39. Leong A, Frawley LS, Neil JD (1983) Neuroendocrine control of prolactin secretion. Annual Review of Physiology 45: 109–113.
40. Liu JY, Stemmer KL (1990) Interaction between aluminium and zinc or copper and its effects on the pituitary–testicular axis. II. Testicular enzyme and serum gonadotropin. Biomedical and Environmental Sciences 3(1): 11–19.
41. Llobet JM, Colomina MT, Sirvent JJ, Domingo JL, Corbella J (1995) Reproductive toxicity of aluminum in male mice. Toxicological Sciences 25(1): 45–51.
42. Mahieu S, Calvo ML (1998) Effect of chronic poisoning with aluminium on the renal handling of phosphate in the rat. Toxicology Letters 94(1): 47–56.
43. Mais V, Cetel NS, Muse KN, Quigle WF, Yen SSC (1987) Characterization of the physiological pattern of episodic gonadotropin secretion through the human menstrual cycle. Clinics in Endocrinology and Metabolism 64: 1109–1112.
44. Martin GB, White CL, Markey CM, Blackberry MA (1994) Effects of dietary zinc deficiency on the reproductive system of young male sheep: testicular growth and the secretion of inhibin and testosterone. Journal of Reproduction and Fertility 101(1): 87–96.
45. Moselhy W, Helmy N, Abdel-Halim B, Nabil T, Abdel-Hamid M (2012) Role of ginger against the reproductive toxicity of aluminium chloride in albino male rats. Reproduction in Domestic Animals 47(2): 335–343.
46. Newairy AS, Salama AF, Hussien HM, Yousef MI (2009) Propolis alleviates aluminium-induced lipid peroxidation and biochemical parameters in male rats. Food and Chemical Toxicology 47(6): 1093–1098.
47. Peters T (1968) Determination of total protein. Clinical Chemistry 14: 1147.
48. Peto MV (2010) Aluminium and iron in humans: bioaccumulation, pathology and removal. Rejuvenation Research 13(5): 589–598.
49. Platt B, Büsselberg D (1994) Actions of aluminium on voltage-activated calcium channel currents. Cell and Molecular Neurobiology 14(6): 819–829.
50. Poirier J, Semple H, Davies J, Lapointe R, Dziwenka M, Hiltz M et al. (2011) Double-blind, vehicle-controlled randomized twelve-month neurodevelopmental toxicity study of common aluminium salts in the rat. Neuroscience 193: 338–362.
51. Rajendar B, Bharavi K, Rao GS, Kishore PV, Kumar PR, Kumar CS et al. (2011) Protective effect of alpha-tocopherol on biochemical and histological alterations induced by cadmium in rat testes. Indian Journal of Physiology and Pharmacology 55(3): 213–220.
52. Schmit JM (1964) Colorimetric Determination of Total Lipids Using Sulfophosphovanilic Mixture. Lyon, France: BioMerieux Company of France.
53. Shahraki MR, Palan Mony EY, Zahed Asl S, Sarkaki AR, Shahraki AR (2008) Effect of aluminium chloride injection in lateral ventricle on serum gonadotropines, testosterone and spermatogenesis in rats. Journal of Medical Sciences 8(4): 410–414.
54. Smith OB, Akinbamizo OO (2000) Micronutrients and reproduction in farm animals. Animal Reproduction Science (60–61): 549–560.
55. Suleiman SA, Ali ME, Zaki ZM, El Malik EM, Nasr MA (1996) Lipid peroxidation and human sperm motility: protective role of vitamin E. Journal of Andrology 17(5): 530–537.
56. Sun H, Hu C, Jia L, Zhu Y, Zhao H, Shao B et al. (2011) Effect of aluminium exposure on serum sex hormones and androgen receptors expression in male rats. Biological Trace Element Research 144(1–3): 1050–1058.
57. Suzuki T, Nakajima K, Yamamoto A, Yamanaka H (1995) Metallothionein binding zinc inhibits nuclear chromatin decondensation of human spermatozoa. Andrologia 27(3): 161–164.
58. Takayama M, Itoh S, Nagasaki T, Tanimizu I (1977) A new enzymatic method for determination of serum choline-containing phospholipids. Clinica Chimica Acta 79(1): 93–98.
59. Tandon SK, Tewari PC (1988) Effect of co-exposure to ethanol and cadmium in rats. Bulletin of Environmental Contamination and Toxicology 39: 633–640.
60. Traber MG, Atkinson (2007) Vitamin E, antioxidant and nothing more. Free Radical Biology and Medicine 43(1): 4–15.
61. Tripathi S, Mahdi AA, Nawab A, Chander R, Hasan M, Siddiqui MS et al. (2009) Influence of age on aluminium induced lipid peroxidation and neurolipofuscin in frontal cortex of rat brain: a behavioral, biochemical and ultrastructural study. Brain Research 1253: 107–116.
62. Turner TT, Lysiak JL (2008) Oxidative stress: a common factor in testicular dysfunction. Journal of Andrology 29: 488–498.
63. Verstraeten SV, Nogueira LV, Schreier S, Oteiza PI (1997) Effect of trivalent metal ions on phase separation and membrane lipid packing: role in lipid peroxidation. Archives of Biochemistry and Biophysics 338(1): 121–127.
64. Verstraeten SV, Aimo L, Oteiza PI (2008) Aluminium and lead: molecular mechanisms of brain toxicity. Archives of Toxicology 82(11): 789–802.
65. Vigueras-Villaseñor RM, Ojeda I, Gutierrez-Pérez O, Chavez-Saldaña M, Cuevas O, Maria DS et al. (2011) Protective effect of α-tocopherol on damage to rat testes by experimental cryptorchidism. International Journal of Experimental Pathology 92(2): 13–19.
66. Wang B, Xing W, Zhao Y, Deng X (2010) Effect of chronic aluminium exposure on memory through multiple signal transduction pathways. Environmental Toxicology and Pharmacology 29(3): 308–313.
67. Wang S, Wang G, Barton BE, Murphy TF, Huang HF (2007) Beneficial effects of vitamin E in sperm functions in the rat after spinal cord injury. Journal of Andrology 28(2): 334–341.
68. Wroblewski N, Schill WB, Henkel R (2003) Metal chelators change the human sperm motility pattern. Fertility and Sterility 79(3): 1584–1589.
69. Yin HP, Xu JP (2011) Effect of vitamin E on reproductive hormones and testis structure in chronic dioxin-treated mice. Toxicology and Industrial Health. Epub ahead of print 1 June 2011. DOI: 0748233711408381.
70. Yousef MI (2010) Vitamin E modulates reproductive toxicity of pyrethroid lambda-cyhalothrin in male rabbits. Food and Chemical Toxicology 48(5): 1152–1159.
71. Yousef MI, Salama AF (2009) Propolis protection from reproductive toxicity caused by aluminium chloride in male rats. Food and Chemical Toxicology 47: 1168–1175.
72. Yousef MI, Abdallah GA, Kamel KI (2003) Effect of ascorbic acid and vitamin E supplementation on semen quality biochemical parameters of male rabbits. Animal Reproduction Science 76: 99–111.
73. Yousef MI, El-Morsy AM, Hassan MS (2005) Aluminium-induced deterioration in reproductive performance and seminal plasma biochemistry of male rabbits: protective role of ascorbic acid. Toxicology 215(1–2): 97–107.
74. Zingg JM (2007) Vitamin E: an overview of major research directions. Molecular Aspects of Medicine 28(5–6): 400–422.