Propolis protection from reproductive toxicity caused by aluminium chloride in male rats

Food and Chemical Toxicology

Volumn 47, Issue 6, 2009, Pages 1168-1175

  Yousef, Mokhtar I ^a   Salama, Afrah F ^b  

^a Alexandria University   (Egypt)

^b Faculty of Science   (Egypt)

Author keywords

Aluminium chloride; Free radicals; Male rats; Propolis; Reproductive toxicity; Testosterone

Indexed keywords

17 OXOSTEROID; ALUMINUM CHLORIDE; CATALASE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; PROPOLIS; TESTOSTERONE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVITY; EPIDIDYMIS; HISTOPATHOLOGY; MALE; NONHUMAN; RAT; REPRODUCTIVE TOXICITY; SEMEN ABNORMALITY; SEMINAL VESICLE; SEMINIFEROUS TUBULE; SPERMATOZOON COUNT; SPERMATOZOON DENSITY; SPERMATOZOON MOTILITY; TESTIS ATROPHY; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL; THERAPY EFFECT; TREATMENT DURATION; TREATMENT OUTCOME; TREATMENT RESPONSE;

17-HYDROXYSTEROID DEHYDROGENASES; ALUMINUM COMPOUNDS; ANIMALS; ANTIOXIDANTS; CHLORIDES; EPIDIDYMIS; MALE; ORGAN SIZE; PROPOLIS; RATS; RATS, WISTAR; REPRODUCTION; SEMEN; SEMINAL VESICLES; SPERM COUNT; SPERM MOTILITY; TESTICULAR DISEASES; TESTIS; TESTOSTERONE; THIOBARBITURIC ACID REACTIVE SUBSTANCES;

RATTUS;

EID: 67349274360     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2009.02.006     Document Type: Article

References (58)

1. Aitken R.J. Free radicals, lipid peroxidation and sperm function. Reprod. Fertil. Dev. 7 (1995) 659-668
2. Bataineh H., Al-Hamood M.H., and Elbetieha A.M. Assessment of aggressive, sexual behavior and fertility in adult male rat following long term ingestion of four industrial metals salts. Hum. Exp. Toxicol. 17 (1998) 570-579
3. Bazo A.P., Rodrigues M.A.M., Sforcin J.M., Camargo J.L.V., Ribeiro L.R., and Salvadori D.M.F. Protective action of propolis on the rat colon carcinogenesis. Teratog. Carcinog. Mutag. 22 (2002) 183-194
4. Belles M., Albina M.L., Sanchez D.J., and Domingo J.L. Lack of protective effects of dietary silicon on aluminium-induced maternal and developmental toxicity in mice. Pharmacol. Toxicol. 85 (1999) 1-6
5. Beutler E., Duron O., and Kelly B.M. An improved method for the detection of blood glutathione. J. Lab. Clin. Med. 61 (1963) 882-888
6. Blom E. A one-minute live-dead sperm stain by means of eosinnigrosin. J. Fertil. Steril. 1 (1950) 176-177
7. Castaldo S., and Capasso F. Propolis, an old remedy used in modern medicine. Fitoterapia 73 (2002) 1-6
8. Cranmer J.M., Wilkins J.D., Cannon D.J., and Smith L. Fetal-placental-maternal uptake of aluminium in mice following gestational exposure. Neurotoxicology 7 (1986) 601-608
9. Dawson E.B., Ritter S., Harris W.A., Evans D.R., and Powell L.C. Comparison of sperm viability with seminal plasma metal levels. Biol. Trace Elem. Res. 64 (1998) 215-223
10. DeLeve L.D., and Kaplowitz N. Glutathione metabolism and its role in hepatotoxicity. Pharmacol. Ther. 52 (1991) 230-287
11. Dobashi M., Fujisawa M., Yamazaki T., Okuda Y., Kanzaki M., Tatsumi N., Tsuji T., Okada H., and Kamidono S. Inhibition of steroidogenesis in Leydig cells by exogenous nitric oxide occurs independently of steroidogenic acute regulatory protein (star) mRNA. Arch. Androl. 47 (2001) 203-209
12. Drury R.A.B., and Wallington E.A. Carleton's Histological Technique. fifth ed (1980), Oxford University Press, Oxford, New York, Toronto
13. Esterbauer H., and Cheeseman K.H. Determination of aldehydic lipid peroxidation products: malonaldehyde and 4-hydroxynonenal. Methods Enzymol. 186 (1990) 407-421
14. Exley C. Does antiperspirant use increase the risk of aluminium-related disease, including Alzheimer's disease? Mol. Med. Today 4 (1998) 107-116
15. Flora S.J.S., Mehta A., Satsangi K., Kannan G.M., and Gupta M. Aluminum induced oxidative stress in rat brain: response to combined administration of citric acid and HEDTA. Comp. Biochem. Physiol. Part C 134 (2003) 319-328
16. Gomez M., Esparza J.L., Nogues M.R., Giralt M., Cabre M., and Domingo J.L. Pro-oxidant activity of aluminum in the rat hippocampus: gene expression of antioxident enzymes after melatonin administration. Free Radic. Biol. Med. 38 (2005) 104-111
17. Gomez M., Sanchez D.J., Llobet J.M., Corbella J., and Domingo J.L. The effect of age on aluminum retention in rats. Toxicology 16 (1997) 1-8
18. Gonzalez R., Rernirez D., and Rodriguez S. Hepatoprotective effects of propolis extract on paracetarnol induced liver damage in mice. Phytother. Res. 8 (1994) 229-232
19. Guo C., Lu Y., and H G.W. The influence of aluminum exposure on male reproduction and offspring in mice. Environ. Toxicol. Pharmacol. 20 (2005) 135-141
20. Guo C.H., Huang C.J., Yeh M.S., and Hsu G.S.W. Aluminium induced suppression of testosterone through nitric oxide production in male mice. Environ. Toxicol. Pharmacol. 19 (2005) 33-40
21. Habig W.H., Pabst M.J., and Jakoby W.B. Glutathione S-transferases: The first enzymatic step in mercapturic acid formation. J. Biol. Chem. 249 (1974) 7130-7139
22. Harris S.R., Panaro N.J., and Thorgeirsson U.P. Oxidative stress contributes to the anti-proliferative effects of flavone acetic acid on endothelial cells. Anticancer Res. 20 (2000) 2249-2254
23. Jasprica D., Mornar A., Debeljak Z., Smolcic-Bubalo A., Medic-Saric M., Mayer L., Romic Z., Bucan K., Balog T., Sobocanec S., and Sverko V. In vivo study of propolis supplementation effects on antioxidative status and red blood cells. J. Ethnopharmacol. 110 (2007) 548-554
24. Kanbura M., Eraslan G., and Silici S. Antioxidant effect of propolis against exposure to propetamphos in rats. Ecotoxicol. Environ. Safety 72 (2009) 900-915
25. Katryna B., and Anita P.P. Purification of rat testicular microsomal 17-Ketosteroid reductase. Evidence that 17-ketosteroid reductase and 17-β-Hydroxysteroid dehydrogenase are distinct enzymes. J. Biol. Chem 255 (1980) 5552-5559
26. Khalil M.L. Biological activity of bee propolis in health and disease. Asian Pac. J. Cancer Prev. 7 (2006) 22-31
27. Khattab I.K.F. Histological and ultrastructural studies on the testis of rat after treatment with aluminium chloride. Austr. J. Basic Appl. Sci. 1 (2007) 63-72
28. Khayyal M.T., El-Ghazaly M.A., and El-Khatib A.S. Mechanisms involved in the anti-inflammatory effect of propolis extract. Drugs Exp. Clin. Res. 19 (1993) 197-203
29. Kim J.G., and Parthasarathy S. Oxidation and the spermatozoa. Semen. Reprod. Endocrinol. 16 (1998) 235-239
30. Kostic T.S., Andric S.A., Maric D., and Kovacevic R.Z. Inhibitory effects of stress-activated nitric oxide on antioxidant enzymes and testicular steroidogenesis. J. Steroid. Biochem. Mol. Biol. 75 (2000) 299-305
31. Krasovskii G.N., Vasukovich L.Y., and Chariev O.G. Experimental study of biological effects of leads and aluminum following oral administration. Environ. Health Perspect. 30 (1979) 47-51
32. Lee K.G., Shibamoto T., Takeoka G.R., Lee S.E., Kim J.H., and Park B.S. Inhibitory effects of plant-derived flavonoids and phenolic acids on malonaldehyde formation from ethyl arachidonate. J. Agricul. Food Chem. 51 (2003) 7203-7207
33. Linder R.E., Klinefetter G.R., and Strader L.F. Dibromoacetic acid affects reproductive competence and sperm quality in the male rats. Fund. Appl. Toxicol. 28 (1995) 9-17
34. Llobet J.M., Colomina M.T., and Sirvent J.J. Reproductive toxicology of aluminum in male mice. Fund. Appl. Toxicol. 25 (1995) 45-51
35. Lowry O.H., Rosebrough N.J., Farr A.L., and Randall R.J. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193 (1951) 269-275
36. Mani F., Damasceno H.C., Novelli E.L., Martins E.A., and Sforcin J.M. Propolis: effect of different concentrations, extracts and intake period on seric biochemical variables. J. Ethnopharmacol. 105 (2006) 95-98
37. Matsushige K.I., Kusumoto T., Yamamoto Y., Kadota S., and Namba T. Quality evaluation of propolis. 1. A comparative study on radical scavenging effects of propolis and vespae nidus. J. Trad. Med. 12 (1995) 45-53
38. Park E.H., and Kahng J.H. Suppressive effects of propolis in rat adjuvant arthritis. Arch. Pharm. Res. 22 (1999) 554-558
39. Reusche E., Lindner B., and Arnholdt H. Widespread aluminum deposition in extracerebral organ systems of patients with dialysis-associated encephalopathy. Virchows Arc. 424 (1994) 105-112
40. Russo A., Troncoso N., Sanchez F., Garbarino J.A., and Vanella A. Propolis protects human spermatozoa from DNA damage caused by benzo[a]pyrene and exogenous reactive oxygen species. Life Sci. 78 (2006) 1401-1406
41. Sarkar M., Roy Chaudhury G., Chattopadhyay A., and Biswas N.M. Effect of sodium arsenate on spermatogenesis, plasma gonadotrophins and testosterone in rats. Asian J. Androl. 5 (2003) 27-31
42. Sforcin J.M., Fernandes A., Lopes C.A.M., Bankova V., and Funari S.R.C. Seasonal effect on Brazilian propolis antibacterial activity. J. Ethnopharm. 73 (2000) 243-249
43. Sforcin J.M., Kaneno R., and Funari S.R.C. Absence of seasonal effect on the immunomodulatory action of Brazilian propolis on natural killer activity. J. Venom. Animals Toxins 8 (2002) 19-29
44. 3. J. Bioinorg. Chem. Appl. 1 (2003) 215-225
45. Sharpe R.M. Intratesticular control of steroidogenesis. Clin. Endocrinol. 33 (1990) 787-791
46. Sobocanec S., Sverko V., Balog T., Saric A., Rusak G., Likic S., Kusic B., Katalinic V., Radic S., and Marotti T. Oxidant/antioxidant properties of Croatian native propolis. J. Agric. Food Chem. 54 (2006) 8018-8026
47. Turner T.T., and Lysiak J.L. Oxidative stress: a common factor in testicular dysfunction. J. Androl. 29 (2008) 488-498
48. Venturini-Soriano M., and Berthon G. Aluminum speciation studies in biological fluids Part 7. A quantitative investigation of aluminum(III)-malate complex equilibria and their potential implications for aluminum metabolism and toxicity. J. Inorg. Bioch. 85 (2001) 143-154
49. Verma A., and Kanwar K.C. Effect of vitamin E on human sperm motility and lipid peroxidation in vitro. Asian J. Androl. 1 (1999) 151-154
50. Xu J.B., Yuan X.F., and Lang P.Z. Determination of catalase activity and catalase inhibition by ultraviolet spectrophotometry. Chin. Environ. Chem. 16 (1997) 73-76
51. Yousef M.I. Aluminium-induced changes in hemato-biochemical parameters, lipid peroxidation and enzyme activities of male rabbits: Protective role of ascorbic acid. Toxicology 199 (2004) 47-57
52. Yousef M.I., El-Demerdash F.M., and Al-Salhen K.S. Protective role of isoflavones against the toxic effect of cypermethrin on semen quality and testosterone levels of rabbits. J. Environ. Sci. Health Part B 38 (2003) 463-478
53. Yousef M.I., El-Demerdash F.M., Kamel K.I., and Al-Salhen K.S. Changes in some hematological and biochemical indices of rabbits induced by isoflavones and cypermethrin. Toxicology 189 (2003) 223-234
54. Yousef M.I., El-Morsy A.M.A., and Hassan M.S. Aluminium induced deterioration in reproductive performance and seminal plasma biochemistry of male rabbits: protective role of ascorbic acid. Toxicology 215 (2005) 97-107
55. Yousef M.I., Esmail A.M., and Baghdadi H.H. Effect of isoflavones on reproductive performance, testosterone levels, lipid peroxidation and seminal plasma biochemistry of male rabbits. J. Environ. Sci. Health Part B 39 (2004) 819-833
56. Yousef M.I., Kamel I.K., Esmail A.M., and Baghdadi H.H. Antioxidant activities and lipid lowering effects of isoflavone in male rabbits. Food Chem. Toxicol. 42 (2004) 1497-1503
57. Yousef M.I., Kamel K.I., El-Guendi M.I., and El-Demerdash F.M. An in vitro study on reproductive toxicity of aluminium chloride on rabbit sperm: the protective role of some antioxidants. Toxicology 239 2007 (2007) 213-223
58. Zatta P., Lain E., and Cagnolini C. Effects of aluminum on activity of Krebs cycle enzymes and glutamate dehydrogenase in rat brain homogenate. Eur. J. Biochem. 267 (2000) 3049-3055