-
1
-
-
0027964261
-
Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia
-
PubMed PMID: 7913883,J 29
-
Shiang R., Thompson L.M., Zhu Y.Z., Church D.M., Fielder T.J., Bocian M., et al. Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia. Cell 1994 Jul 29, 78(2):335-342. PubMed PMID: 7913883.
-
(1994)
Cell
, vol.78
, Issue.2
, pp. 335-342
-
-
Shiang, R.1
Thompson, L.M.2
Zhu, Y.Z.3
Church, D.M.4
Fielder, T.J.5
Bocian, M.6
-
2
-
-
0028093135
-
Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia
-
PubMed PMID: 8078586, S 15
-
Rousseau F., Bonaventure J., Legeai-Mallet L., Pelet A., Rozet J.M., Maroteaux P., et al. Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia. Nature 1994 Sep 15, 371(6494):252-254. PubMed PMID: 8078586.
-
(1994)
Nature
, vol.371
, Issue.6494
, pp. 252-254
-
-
Rousseau, F.1
Bonaventure, J.2
Legeai-Mallet, L.3
Pelet, A.4
Rozet, J.M.5
Maroteaux, P.6
-
3
-
-
0028872752
-
Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3
-
PubMed PMID: 7773297, M
-
Tavormina P.L., Shiang R., Thompson L.M., Zhu Y.Z., Wilkin D.J., Lachman R.S., et al. Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3. Nat Genet 1995 Mar, 9(3):321-328. PubMed PMID: 7773297.
-
(1995)
Nat Genet
, vol.9
, Issue.3
, pp. 321-328
-
-
Tavormina, P.L.1
Shiang, R.2
Thompson, L.M.3
Zhu, Y.Z.4
Wilkin, D.J.5
Lachman, R.S.6
-
4
-
-
0029298121
-
Stop codon FGFR3 mutations in thanatophoric dwarfism type 1
-
PubMed PMID: 7647778, M
-
Rousseau F., Saugier P., Le Merrer M., Munnich A., Delezoide A.L., Maroteaux P., et al. Stop codon FGFR3 mutations in thanatophoric dwarfism type 1. Nat Genet 1995 May, 10(1):11-12. PubMed PMID: 7647778.
-
(1995)
Nat Genet
, vol.10
, Issue.1
, pp. 11-12
-
-
Rousseau, F.1
Saugier, P.2
Le Merrer, M.3
Munnich, A.4
Delezoide, A.L.5
Maroteaux, P.6
-
5
-
-
13044278311
-
A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3
-
PubMed PMID: 10200283. Pubmed Central PMCID: 16353, A 13
-
Wang Y., Spatz M.K., Kannan K., Hayk H., Avivi A., Gorivodsky M., et al. A mouse model for achondroplasia produced by targeting fibroblast growth factor receptor 3. Proc Natl Acad Sci USA 1999 Apr 13, 96(8):4455-4460. PubMed PMID: 10200283. Pubmed Central PMCID: 16353.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.8
, pp. 4455-4460
-
-
Wang, Y.1
Spatz, M.K.2
Kannan, K.3
Hayk, H.4
Avivi, A.5
Gorivodsky, M.6
-
6
-
-
0029917507
-
Fibroblast growth factor receptor 3 is a negative regulator of bone growth
-
PubMed PMID: 8601314, M 22
-
Deng C., Wynshaw-Boris A., Zhou F., Kuo A., Leder P. Fibroblast growth factor receptor 3 is a negative regulator of bone growth. Cell 1996 Mar 22, 84(6):911-921. PubMed PMID: 8601314.
-
(1996)
Cell
, vol.84
, Issue.6
, pp. 911-921
-
-
Deng, C.1
Wynshaw-Boris, A.2
Zhou, F.3
Kuo, A.4
Leder, P.5
-
7
-
-
11144358656
-
Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway
-
PubMed PMID: 14702637, J
-
Yasoda A., Komatsu Y., Chusho H., Miyazawa T., Ozasa A., Miura M., et al. Overexpression of CNP in chondrocytes rescues achondroplasia through a MAPK-dependent pathway. Nat Med 2004 Jan, 10(1):80-86. PubMed PMID: 14702637.
-
(2004)
Nat Med
, vol.10
, Issue.1
, pp. 80-86
-
-
Yasoda, A.1
Komatsu, Y.2
Chusho, H.3
Miyazawa, T.4
Ozasa, A.5
Miura, M.6
-
8
-
-
84908571755
-
Statin treatment rescues FGFR3 skeletal dysplasia phenotypes
-
PubMed PMID: 25231866, S 25
-
Yamashita A., Morioka M., Kishi H., Kimura T., Yahara Y., Okada M., et al. Statin treatment rescues FGFR3 skeletal dysplasia phenotypes. Nature 2014 Sep 25, 513(7519):507-511. PubMed PMID: 25231866.
-
(2014)
Nature
, vol.513
, Issue.7519
, pp. 507-511
-
-
Yamashita, A.1
Morioka, M.2
Kishi, H.3
Kimura, T.4
Yahara, Y.5
Okada, M.6
-
9
-
-
1042266622
-
Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth
-
PubMed PMID: 14612457, F 6
-
Wu S., De Luca F. Role of cholesterol in the regulation of growth plate chondrogenesis and longitudinal bone growth. J Biol Chem 2004 Feb 6, 279(6):4642-4647. PubMed PMID: 14612457.
-
(2004)
J Biol Chem
, vol.279
, Issue.6
, pp. 4642-4647
-
-
Wu, S.1
De Luca, F.2
-
10
-
-
73549119107
-
Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth
-
PubMed PMID: 20196782, S
-
Woods A., James C.G., Wang G., Dupuis H., Beier F. Control of chondrocyte gene expression by actin dynamics: a novel role of cholesterol/Ror-alpha signalling in endochondral bone growth. J Cell Mol Med 2009 Sep, 13(9B):3497-3516. PubMed PMID: 20196782.
-
(2009)
J Cell Mol Med
, vol.13
, Issue.9 B
, pp. 3497-3516
-
-
Woods, A.1
James, C.G.2
Wang, G.3
Dupuis, H.4
Beier, F.5
-
11
-
-
80455143730
-
Cartilage biology in osteoarthritis-lessons from developmental biology
-
PubMed PMID: 21947178, N
-
Pitsillides A.A., Beier F. Cartilage biology in osteoarthritis-lessons from developmental biology. Nat Rev Rheumatol 2011 Nov, 7(11):654-663. PubMed PMID: 21947178.
-
(2011)
Nat Rev Rheumatol
, vol.7
, Issue.11
, pp. 654-663
-
-
Pitsillides, A.A.1
Beier, F.2
-
12
-
-
3042826465
-
Simvastatin reduces MMP-3 level in interleukin 1beta stimulated human chondrocyte culture
-
PubMed PMID: 15194586. Pubmed Central PMCID: 1755052, J
-
Lazzerini P.E., Capecchi P.L., Nerucci F., Fioravanti A., Chellini F., Piccini M., et al. Simvastatin reduces MMP-3 level in interleukin 1beta stimulated human chondrocyte culture. Ann Rheum Dis 2004 Jul, 63(7):867-869. PubMed PMID: 15194586. Pubmed Central PMCID: 1755052.
-
(2004)
Ann Rheum Dis
, vol.63
, Issue.7
, pp. 867-869
-
-
Lazzerini, P.E.1
Capecchi, P.L.2
Nerucci, F.3
Fioravanti, A.4
Chellini, F.5
Piccini, M.6
-
13
-
-
73249146659
-
Protective effect of atorvastatin in cultured osteoarthritic chondrocytes
-
PubMed PMID: 19623662, J
-
Simopoulou T., Malizos K.N., Poultsides L., Tsezou A. Protective effect of atorvastatin in cultured osteoarthritic chondrocytes. J Orthop Res 2010 Jan, 28(1):110-115. PubMed PMID: 19623662.
-
(2010)
J Orthop Res
, vol.28
, Issue.1
, pp. 110-115
-
-
Simopoulou, T.1
Malizos, K.N.2
Poultsides, L.3
Tsezou, A.4
-
14
-
-
77954218207
-
Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage
-
PubMed PMID: 20417291, J
-
Sverdrup F.M., Yates M.P., Vickery L.E., Klover J.A., Song L.R., Anglin C.P., et al. Protein geranylgeranylation controls collagenase expression in osteoarthritic cartilage. Osteoarthritis Cartilage 2010 Jul, 18(7):948-955. PubMed PMID: 20417291.
-
(2010)
Osteoarthritis Cartilage
, vol.18
, Issue.7
, pp. 948-955
-
-
Sverdrup, F.M.1
Yates, M.P.2
Vickery, L.E.3
Klover, J.A.4
Song, L.R.5
Anglin, C.P.6
-
15
-
-
59249095198
-
Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation
-
PubMed PMID: 18672387, F
-
Akasaki Y., Matsuda S., Nakayama K., Fukagawa S., Miura H., Iwamoto Y. Mevastatin reduces cartilage degradation in rabbit experimental osteoarthritis through inhibition of synovial inflammation. Osteoarthritis Cartilage 2009 Feb, 17(2):235-243. PubMed PMID: 18672387.
-
(2009)
Osteoarthritis Cartilage
, vol.17
, Issue.2
, pp. 235-243
-
-
Akasaki, Y.1
Matsuda, S.2
Nakayama, K.3
Fukagawa, S.4
Miura, H.5
Iwamoto, Y.6
-
16
-
-
77952705182
-
Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes
-
PubMed PMID: 20512918. Pubmed Central PMCID: 2883292, J 1
-
Beier F., Loeser R.F. Biology and pathology of Rho GTPase, PI-3 kinase-Akt, and MAP kinase signaling pathways in chondrocytes. J Cell Biochem 2010 Jun 1, 110(3):573-580. PubMed PMID: 20512918. Pubmed Central PMCID: 2883292.
-
(2010)
J Cell Biochem
, vol.110
, Issue.3
, pp. 573-580
-
-
Beier, F.1
Loeser, R.F.2
-
17
-
-
11844305614
-
Association of statin use and development and progression of hip osteoarthritis in elderly women
-
PubMed PMID: 15630734, J
-
Beattie M.S., Lane N.E., Hung Y.Y., Nevitt M.C. Association of statin use and development and progression of hip osteoarthritis in elderly women. J Rheumatol 2005 Jan, 32(1):106-110. PubMed PMID: 15630734.
-
(2005)
J Rheumatol
, vol.32
, Issue.1
, pp. 106-110
-
-
Beattie, M.S.1
Lane, N.E.2
Hung, Y.Y.3
Nevitt, M.C.4
-
18
-
-
84872066639
-
Associations between statin use and changes in pain, function and structural progression: a longitudinal study of persons with knee osteoarthritis
-
PubMed PMID: 23172752, F
-
Riddle D.L., Moxley G., Dumenci L. Associations between statin use and changes in pain, function and structural progression: a longitudinal study of persons with knee osteoarthritis. Ann Rheum Dis 2013 Feb, 72(2):196-203. PubMed PMID: 23172752.
-
(2013)
Ann Rheum Dis
, vol.72
, Issue.2
, pp. 196-203
-
-
Riddle, D.L.1
Moxley, G.2
Dumenci, L.3
-
19
-
-
84859494190
-
Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study
-
PubMed PMID: 21989540, M
-
Clockaerts S., Van Osch G.J., Bastiaansen-Jenniskens Y.M., Verhaar J.A., Van Glabbeek F., Van Meurs J.B., et al. Statin use is associated with reduced incidence and progression of knee osteoarthritis in the Rotterdam study. Ann Rheum Dis 2012 May, 71(5):642-647. PubMed PMID: 21989540.
-
(2012)
Ann Rheum Dis
, vol.71
, Issue.5
, pp. 642-647
-
-
Clockaerts, S.1
Van Osch, G.J.2
Bastiaansen-Jenniskens, Y.M.3
Verhaar, J.A.4
Van Glabbeek, F.5
Van Meurs, J.B.6
-
20
-
-
84879550749
-
Statin use and clinical osteoarthritis in the general population: a longitudinal study
-
PubMed PMID: 23471638. Pubmed Central PMCID: 3682050, J
-
Kadam U.T., Blagojevic M., Belcher J. Statin use and clinical osteoarthritis in the general population: a longitudinal study. J Gen Intern Med 2013 Jul, 28(7):943-949. PubMed PMID: 23471638. Pubmed Central PMCID: 3682050.
-
(2013)
J Gen Intern Med
, vol.28
, Issue.7
, pp. 943-949
-
-
Kadam, U.T.1
Blagojevic, M.2
Belcher, J.3
-
21
-
-
84897969077
-
Use of statins is associated with a lower prevalence of generalised osteoarthritis
-
PubMed PMID: 24347568. Pubmed Central PMCID: 3995213, M
-
Valdes A.M., Zhang W., Muir K., Maciewicz R.A., Doherty S., Doherty M. Use of statins is associated with a lower prevalence of generalised osteoarthritis. Ann Rheum Dis 2014 May, 73(5):943-945. PubMed PMID: 24347568. Pubmed Central PMCID: 3995213.
-
(2014)
Ann Rheum Dis
, vol.73
, Issue.5
, pp. 943-945
-
-
Valdes, A.M.1
Zhang, W.2
Muir, K.3
Maciewicz, R.A.4
Doherty, S.5
Doherty, M.6
-
22
-
-
80051485778
-
Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes
-
PubMed PMID: 21835001. Pubmed Central PMCID: 3239372
-
Yan D., Chen D., Cool S.M., van Wijnen A.J., Mikecz K., Murphy G., et al. Fibroblast growth factor receptor 1 is principally responsible for fibroblast growth factor 2-induced catabolic activities in human articular chondrocytes. Arthritis Res Ther 2011, 13(4):R130. PubMed PMID: 21835001. Pubmed Central PMCID: 3239372.
-
(2011)
Arthritis Res Ther
, vol.13
, Issue.4
, pp. R130
-
-
Yan, D.1
Chen, D.2
Cool, S.M.3
van Wijnen, A.J.4
Mikecz, K.5
Murphy, G.6
-
23
-
-
33744763965
-
Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice
-
PubMed PMID: 16624844, J 1
-
Valverde-Franco G., Binette J.S., Li W., Wang H., Chai S., Laflamme F., et al. Defects in articular cartilage metabolism and early arthritis in fibroblast growth factor receptor 3 deficient mice. Hum Mol Genet 2006 Jun 1, 15(11):1783-1792. PubMed PMID: 16624844.
-
(2006)
Hum Mol Genet
, vol.15
, Issue.11
, pp. 1783-1792
-
-
Valverde-Franco, G.1
Binette, J.S.2
Li, W.3
Wang, H.4
Chai, S.5
Laflamme, F.6
-
24
-
-
84870308824
-
Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice
-
PubMed PMID: 22833219. Pubmed Central PMCID: 3690192, D
-
Weng T., Yi L., Huang J., Luo F., Wen X., Du X., et al. Genetic inhibition of fibroblast growth factor receptor 1 in knee cartilage attenuates the degeneration of articular cartilage in adult mice. Arthritis Rheum 2012 Dec, 64(12):3982-3992. PubMed PMID: 22833219. Pubmed Central PMCID: 3690192.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.12
, pp. 3982-3992
-
-
Weng, T.1
Yi, L.2
Huang, J.3
Luo, F.4
Wen, X.5
Du, X.6
-
25
-
-
84862929910
-
Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells
-
PubMed PMID: 22178754. Pubmed Central PMCID: 3252902, J 3
-
Quarto N., Leonard B., Li S., Marchand M., Anderson E., Behr B., et al. Skeletogenic phenotype of human Marfan embryonic stem cells faithfully phenocopied by patient-specific induced-pluripotent stem cells. Proc Natl Acad Sci USA 2012 Jan 3, 109(1):215-220. PubMed PMID: 22178754. Pubmed Central PMCID: 3252902.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, Issue.1
, pp. 215-220
-
-
Quarto, N.1
Leonard, B.2
Li, S.3
Marchand, M.4
Anderson, E.5
Behr, B.6
-
26
-
-
80053466712
-
Generation of human induced pluripotent stem cells from osteoarthritis patient-derived synovial cells
-
PubMed PMID: 21953087, O
-
Kim M.J., Son M.J., Son M.Y., Seol B., Kim J., Park J., et al. Generation of human induced pluripotent stem cells from osteoarthritis patient-derived synovial cells. Arthritis Rheum 2011 Oct, 63(10):3010-3021. PubMed PMID: 21953087.
-
(2011)
Arthritis Rheum
, vol.63
, Issue.10
, pp. 3010-3021
-
-
Kim, M.J.1
Son, M.J.2
Son, M.Y.3
Seol, B.4
Kim, J.5
Park, J.6
-
27
-
-
84893178514
-
Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis
-
PubMed PMID: 24490617. Pubmed Central PMCID: 3978583
-
Lee J., Kim Y., Yi H., Diecke S., Kim J., Jung H., et al. Generation of disease-specific induced pluripotent stem cells from patients with rheumatoid arthritis and osteoarthritis. Arthritis Res Ther 2014, 16(1):R41. PubMed PMID: 24490617. Pubmed Central PMCID: 3978583.
-
(2014)
Arthritis Res Ther
, vol.16
, Issue.1
, pp. R41
-
-
Lee, J.1
Kim, Y.2
Yi, H.3
Diecke, S.4
Kim, J.5
Jung, H.6
-
28
-
-
84861827675
-
Osteoarthritis: a disease of the joint as an organ
-
PubMed PMID: 22392533. Pubmed Central PMCID: 3366018, J
-
Loeser R.F., Goldring S.R., Scanzello C.R., Goldring M.B. Osteoarthritis: a disease of the joint as an organ. Arthritis Rheum 2012 Jun, 64(6):1697-1707. PubMed PMID: 22392533. Pubmed Central PMCID: 3366018.
-
(2012)
Arthritis Rheum
, vol.64
, Issue.6
, pp. 1697-1707
-
-
Loeser, R.F.1
Goldring, S.R.2
Scanzello, C.R.3
Goldring, M.B.4
-
29
-
-
84890168801
-
Advances in osteoarthritis genetics
-
PubMed PMID: 23868913. Pubmed Central PMCID: 3812881, N
-
Panoutsopoulou K., Zeggini E. Advances in osteoarthritis genetics. J Med Genet 2013 Nov, 50(11):715-724. PubMed PMID: 23868913. Pubmed Central PMCID: 3812881.
-
(2013)
J Med Genet
, vol.50
, Issue.11
, pp. 715-724
-
-
Panoutsopoulou, K.1
Zeggini, E.2
|