Quinolinic acid toxicity on oligodendroglial cells: Relevance for multiple sclerosis and therapeutic strategies

Journal of Neuroinflammation

Volumn 11, Issue 1, 2014, Pages

  Sundaram, Gayathri ^a,b   Brew, Bruce J ^a,c   Jones, Simon P ^a   Adams, Seray ^b,d   Lim, Chai K ^a,b,d   Guillemin, Gilles J ^a,b,d  

^a St Vincent's Centre for Applied Medical Research Applied Neurosciences Program Peter Duncan Neurosciences Research Unit   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c ST VINCENT S HOSPITAL   (Australia)

^d MACQUARIE UNIVERSITY   (Australia)

Author keywords

Excitotoxicity; Multiple sclerosis; Neurodegeneration; Neuroinflammation; Oligodendrocyte; Quinolinic acid

Indexed keywords

1 METHYL LEVO TRYPTOPHAN; BERBERINE; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; INDOLEAMINE 2,3 DIOXYGENASE INHIBITOR; INDOXIMOD; KYNURENINE; KYNURENINE AMINOTRANSFERASE; KYNURENINE AMINOTRANSFERASE 1; KYNURENINE AMINOTRANSFERASE 2; LACTATE DEHYDROGENASE; MONOCLONAL ANTIBODY; QUINOLINIC ACID; TRYPTOPHAN 2,3 DIOXYGENASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; EXCITOTOXICITY; MONOCYTE; MOUSE; MULTIPLE SCLEROSIS; NEUROPROTECTION; NONHUMAN; OLIGODENDROGLIA; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; DRUG EFFECTS; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; METABOLISM; TRANSFORMED CELL LINE;

ANIMALS; ANTIBODIES, MONOCLONAL; CELL LINE; CELL LINE, TRANSFORMED; ENCEPHALOMYELITIS, AUTOIMMUNE, EXPERIMENTAL; KYNURENINE; MICE; MULTIPLE SCLEROSIS; OLIGODENDROGLIA; QUINOLINIC ACID;

EID: 84924853615     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-014-0204-5     Document Type: Article

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