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Volumn 3, Issue 3, 2014, Pages 149-158

Prognostic markers in lung cancer: Is it ready for prime time?

Author keywords

Expression signature; Immunohistochemistry (IHC); Multi gene markers; Prognostic marker; Proteomics

Indexed keywords


EID: 84924803368     PISSN: 22186751     EISSN: 22264477     Source Type: Journal    
DOI: 10.3978/j.issn.2218-6751.2014.06.09     Document Type: Review
Times cited : (48)

References (59)
  • 1
    • 33644982287 scopus 로고    scopus 로고
    • Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy
    • author reply 1220-1
    • Shepherd FA, Tsao MS. Unraveling the mystery of prognostic and predictive factors in epidermal growth factor receptor therapy. J Clin Oncol 2006;24:1219-20; author reply 1220-1.
    • (2006) J Clin Oncol , vol.24 , pp. 1219-1220
    • Shepherd, F.A.1    Tsao, M.S.2
  • 2
    • 34347393745 scopus 로고    scopus 로고
    • Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort crossinstitutional study
    • Taguchi F, Solomon B, Gregorc V, et al. Mass spectrometry to classify non-small-cell lung cancer patients for clinical outcome after treatment with epidermal growth factor receptor tyrosine kinase inhibitors: a multicohort crossinstitutional study. J Natl Cancer Inst 2007;99:838-46.
    • (2007) J Natl Cancer Inst , vol.99 , pp. 838-846
    • Taguchi, F.1    Solomon, B.2    Gregorc, V.3
  • 3
    • 84875394397 scopus 로고    scopus 로고
    • A retrospective analysis of VeriStrat status on outcome of a randomized phase II trial of first-line therapy with gemcitabine, erlotinib, or the combination in elderly patients (age 70 years or older) with stage IIIB/IV nonsmall-cell lung cancer
    • Stinchcombe TE, Roder J, Peterman AH, et al. A retrospective analysis of VeriStrat status on outcome of a randomized phase II trial of first-line therapy with gemcitabine, erlotinib, or the combination in elderly patients (age 70 years or older) with stage IIIB/IV nonsmall-cell lung cancer. J Thorac Oncol 2013;8:443-51.
    • (2013) J Thorac Oncol , vol.8 , pp. 443-451
    • Stinchcombe, T.E.1    Roder, J.2    Peterman, A.H.3
  • 4
    • 84867900616 scopus 로고    scopus 로고
    • Prognostic and predictive role of the VeriStrat plasma test in patients with advanced non-small-cell lung cancer treated with erlotinib or placebo in the NCIC Clinical Trials Group BR.21 trial
    • Carbone DP, Ding K, Roder H, et al. Prognostic and predictive role of the VeriStrat plasma test in patients with advanced non-small-cell lung cancer treated with erlotinib or placebo in the NCIC Clinical Trials Group BR.21 trial. J Thorac Oncol 2012;7:1653-60.
    • (2012) J Thorac Oncol , vol.7 , pp. 1653-1660
    • Carbone, D.P.1    Ding, K.2    Roder, H.3
  • 5
    • 33747074100 scopus 로고    scopus 로고
    • Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation
    • Zhu CQ, Shih W, Ling CH, et al. Immunohistochemical markers of prognosis in non-small cell lung cancer: a review and proposal for a multiphase approach to marker evaluation. J Clin Pathol 2006;59:790-800.
    • (2006) J Clin Pathol , vol.59 , pp. 790-800
    • Zhu, C.Q.1    Shih, W.2    Ling, C.H.3
  • 6
    • 21844434717 scopus 로고    scopus 로고
    • Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer
    • Esposito V, Baldi A, De Luca A, et al. Cell cycle related proteins as prognostic parameters in radically resected non-small cell lung cancer. J Clin Pathol 2005;58:734-9.
    • (2005) J Clin Pathol , vol.58 , pp. 734-739
    • Esposito, V.1    Baldi, A.2    De Luca, A.3
  • 7
    • 21344469517 scopus 로고    scopus 로고
    • Prognostic value of cyclin D1 overexpression in correlation with pRb and p53 status in non-small cell lung cancer (NSCLC)
    • Dworakowska D, Jassem E, Jassem J, et al. Prognostic value of cyclin D1 overexpression in correlation with pRb and p53 status in non-small cell lung cancer (NSCLC). J Cancer Res Clin Oncol 2005;131:479-85.
    • (2005) J Cancer Res Clin Oncol , vol.131 , pp. 479-485
    • Dworakowska, D.1    Jassem, E.2    Jassem, J.3
  • 8
    • 0142138047 scopus 로고    scopus 로고
    • Expression of cyclin D1 but not of cyclin E is an indicator of poor prognosis in small adenocarcinomas of the lung
    • Ikehara M, Oshita F, Ito H, et al. Expression of cyclin D1 but not of cyclin E is an indicator of poor prognosis in small adenocarcinomas of the lung. Oncol Rep 2003;10:137-9.
    • (2003) Oncol Rep , vol.10 , pp. 137-139
    • Ikehara, M.1    Oshita, F.2    Ito, H.3
  • 9
    • 0034780882 scopus 로고    scopus 로고
    • Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II
    • Jin M, Inoue S, Umemura T, et al. Cyclin D1, p16 and retinoblastoma gene product expression as a predictor for prognosis in non-small cell lung cancer at stages I and II. Lung Cancer 2001;34:207-18.
    • (2001) Lung Cancer , vol.34 , pp. 207-218
    • Jin, M.1    Inoue, S.2    Umemura, T.3
  • 10
    • 0035866753 scopus 로고    scopus 로고
    • A riskstratification model of non-small cell lung cancers using cyclin E, Ki-67, and ras p21: different roles of G1 cyclins in cell proliferation and prognosis
    • Dosaka-Akita H, Hommura F, Mishina T, et al. A riskstratification model of non-small cell lung cancers using cyclin E, Ki-67, and ras p21: different roles of G1 cyclins in cell proliferation and prognosis. Cancer Res 2001;61:2500-4.
    • (2001) Cancer Res , vol.61 , pp. 2500-2504
    • Dosaka-Akita, H.1    Hommura, F.2    Mishina, T.3
  • 11
    • 0033626036 scopus 로고    scopus 로고
    • The expression of cyclins D1 and E in predicting short-term survival in squamous cell carcinoma of the lung
    • Anton RC, Coffey DM, Gondo MM, et al. The expression of cyclins D1 and E in predicting short-term survival in squamous cell carcinoma of the lung. Mod Pathol 2000;13:1167-72.
    • (2000) Mod Pathol , vol.13 , pp. 1167-1172
    • Anton, R.C.1    Coffey, D.M.2    Gondo, M.M.3
  • 12
    • 0033843716 scopus 로고    scopus 로고
    • Expression of cyclin D1, Ki-67 and PCNA in non-small cell lung cancer: prognostic significance and comparison with p53 and bcl-2
    • Nguyen VN, Mirejovskỳ P, Mirejovskỳ T, et al. Expression of cyclin D1, Ki-67 and PCNA in non-small cell lung cancer: prognostic significance and comparison with p53 and bcl-2. Acta Histochem 2000;102:323-38.
    • (2000) Acta Histochem , vol.102 , pp. 323-338
    • Nguyen, V.N.1    Mirejovskỳ, P.2    Mirejovskỳ, T.3
  • 13
    • 0034060638 scopus 로고    scopus 로고
    • Relevance of proliferative and proapoptotic factors in non-small-cell lung cancer for patient survival
    • Volm M, Koomägi R. Relevance of proliferative and proapoptotic factors in non-small-cell lung cancer for patient survival. Br J Cancer 2000;82:1747-54.
    • (2000) Br J Cancer , vol.82 , pp. 1747-1754
    • Volm, M.1    Koomägi, R.2
  • 14
    • 0032859124 scopus 로고    scopus 로고
    • Cyclin D1 overexpression is an indicator of poor prognosis in resectable non-small cell lung cancer
    • Keum JS, Kong G, Yang SC, et al. Cyclin D1 overexpression is an indicator of poor prognosis in resectable non-small cell lung cancer. Br J Cancer 1999;81:127-32.
    • (1999) Br J Cancer , vol.81 , pp. 127-132
    • Keum, J.S.1    Kong, G.2    Yang, S.C.3
  • 15
    • 0032786446 scopus 로고    scopus 로고
    • Alterations of expression of Rb, p16(INK4A) and cyclin D1 in non-small cell lung carcinoma and their clinical significance
    • Brambilla E, Moro D, Gazzeri S, et al. Alterations of expression of Rb, p16(INK4A) and cyclin D1 in non-small cell lung carcinoma and their clinical significance. J Pathol 1999;188:351-60.
    • (1999) J Pathol , vol.188 , pp. 351-360
    • Brambilla, E.1    Moro, D.2    Gazzeri, S.3
  • 16
    • 0030809321 scopus 로고    scopus 로고
    • Prognostic role of cyclin D1 in non small cell lung cancer: an immunohistochemical analysis
    • Caputi M, De Luca L, Papaccio G, et al. Prognostic role of cyclin D1 in non small cell lung cancer: an immunohistochemical analysis. Eur J Histochem 1997;41:133-8.
    • (1997) Eur J Histochem , vol.41 , pp. 133-138
    • Caputi, M.1    De Luca, L.2    Papaccio, G.3
  • 17
    • 0029894105 scopus 로고    scopus 로고
    • The prognostic value of NCAM, p53 and cyclin D1 in resected non-small cell lung cancer
    • Kwa HB, Michalides RJ, Dijkman JH, et al. The prognostic value of NCAM, p53 and cyclin D1 in resected non-small cell lung cancer. Lung Cancer 1996;14:207-17.
    • (1996) Lung Cancer , vol.14 , pp. 207-217
    • Kwa, H.B.1    Michalides, R.J.2    Dijkman, J.H.3
  • 18
    • 4544264923 scopus 로고    scopus 로고
    • Evaluation of immunohistochemical markers in non-small cell lung cancer by unsupervised hierarchical clustering analysis: a tissue microarray study of 284 cases and 18 markers
    • Au NH, Cheang M, Huntsman DG, et al. Evaluation of immunohistochemical markers in non-small cell lung cancer by unsupervised hierarchical clustering analysis: a tissue microarray study of 284 cases and 18 markers. J Pathol 2004;204:101-9.
    • (2004) J Pathol , vol.204 , pp. 101-109
    • Au, N.H.1    Cheang, M.2    Huntsman, D.G.3
  • 19
    • 19944427869 scopus 로고    scopus 로고
    • Prognostic implications of molecular and immunohistochemical profiles of the Rb and p53 cell cycle regulatory pathways in primary non-small cell lung carcinoma
    • Burke L, Flieder DB, Guinee DG, et al. Prognostic implications of molecular and immunohistochemical profiles of the Rb and p53 cell cycle regulatory pathways in primary non-small cell lung carcinoma. Clin Cancer Res 2005;11:232-41.
    • (2005) Clin Cancer Res , vol.11 , pp. 232-241
    • Burke, L.1    Flieder, D.B.2    Guinee, D.G.3
  • 20
    • 0034894586 scopus 로고    scopus 로고
    • Alterations of cell cycle regulators are less frequent in advanced nonsmall cell lung cancer than in resectable tumours
    • Gugger M, Kappeler A, Vonlanthen S, et al. Alterations of cell cycle regulators are less frequent in advanced nonsmall cell lung cancer than in resectable tumours. Lung Cancer 2001;33:229-39.
    • (2001) Lung Cancer , vol.33 , pp. 229-239
    • Gugger, M.1    Kappeler, A.2    Vonlanthen, S.3
  • 21
    • 33847416564 scopus 로고    scopus 로고
    • Class III beta-tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: analysis of NCIC JBR.10
    • Sève P, Lai R, Ding K, et al. Class III beta-tubulin expression and benefit from adjuvant cisplatin/vinorelbine chemotherapy in operable non-small cell lung cancer: analysis of NCIC JBR.10. Clin Cancer Res 2007;13:994-9.
    • (2007) Clin Cancer Res , vol.13 , pp. 994-999
    • Sève, P.1    Lai, R.2    Ding, K.3
  • 22
    • 84255206496 scopus 로고    scopus 로고
    • Crossvalidation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials
    • Reiman T, Lai R, Veillard AS, Paris E, et al. Crossvalidation study of class III beta-tubulin as a predictive marker for benefit from adjuvant chemotherapy in resected non-small-cell lung cancer: analysis of four randomized trials. Ann Oncol 2012;23:86-93.
    • (2012) Ann Oncol , vol.23 , pp. 86-93
    • Reiman, T.1    Lai, R.2    Veillard, A.S.3    Paris, E.4
  • 23
    • 33748435058 scopus 로고    scopus 로고
    • DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy
    • Olaussen KA, Dunant A, Fouret P, et al. DNA repair by ERCC1 in non-small-cell lung cancer and cisplatin-based adjuvant chemotherapy. N Engl J Med 2006;355:983-91.
    • (2006) N Engl J Med , vol.355 , pp. 983-991
    • Olaussen, K.A.1    Dunant, A.2    Fouret, P.3
  • 24
    • 84875181563 scopus 로고    scopus 로고
    • ERCC1 isoform expression and DNA repair in non-small-cell lung cancer
    • Friboulet L, Olaussen KA, Pignon JP, et al. ERCC1 isoform expression and DNA repair in non-small-cell lung cancer. N Engl J Med 2013;368:1101-10.
    • (2013) N Engl J Med , vol.368 , pp. 1101-1110
    • Friboulet, L.1    Olaussen, K.A.2    Pignon, J.P.3
  • 25
    • 19944430434 scopus 로고    scopus 로고
    • The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis
    • Mascaux C, Iannino N, Martin B, et al. The role of RAS oncogene in survival of patients with lung cancer: a systematic review of the literature with meta-analysis. Br J Cancer 2005;92:131-9.
    • (2005) Br J Cancer , vol.92 , pp. 131-139
    • Mascaux, C.1    Iannino, N.2    Martin, B.3
  • 26
    • 84881374148 scopus 로고    scopus 로고
    • Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy
    • Shepherd FA, Domerg C, Hainaut P, et al. Pooled analysis of the prognostic and predictive effects of KRAS mutation status and KRAS mutation subtype in early-stage resected non-small-cell lung cancer in four trials of adjuvant chemotherapy. J Clin Oncol 2013;31:2173-81.
    • (2013) J Clin Oncol , vol.31 , pp. 2173-2181
    • Shepherd, F.A.1    Domerg, C.2    Hainaut, P.3
  • 27
    • 20244388951 scopus 로고    scopus 로고
    • Molecular pathologic substaging in 244 stage I non-smallcell lung cancer patients: clinical implications
    • Kwiatkowski DJ, Harpole DH Jr, Godleski J, et al. Molecular pathologic substaging in 244 stage I non-smallcell lung cancer patients: clinical implications. J Clin Oncol 1998;16:2468-77.
    • (1998) J Clin Oncol , vol.16 , pp. 2468-2477
    • Kwiatkowski, D.J.1    Harpole, D.H.2    Godleski, J.3
  • 28
    • 0032959632 scopus 로고    scopus 로고
    • A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers
    • D'Amico TA, Massey M, Herndon JE 2nd, et al. A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers. J Thorac Cardiovasc Surg 1999;117:736-43.
    • (1999) J Thorac Cardiovasc Surg , vol.117 , pp. 736-743
    • D'Amico, T.A.1    Massey, M.2    Herndon, J.E.3
  • 29
    • 70349388721 scopus 로고    scopus 로고
    • Understanding prognostic gene expression signatures in lung cancer
    • Zhu CQ, Pintilie M, John T, et al. Understanding prognostic gene expression signatures in lung cancer. Clin Lung Cancer 2009;10:331-40.
    • (2009) Clin Lung Cancer , vol.10 , pp. 331-340
    • Zhu, C.Q.1    Pintilie, M.2    John, T.3
  • 30
    • 62449271525 scopus 로고    scopus 로고
    • Prognostic gene signatures for non-small-cell lung cancer
    • Boutros PC, Lau SK, Pintilie M, et al. Prognostic gene signatures for non-small-cell lung cancer. Proc Natl Acad Sci U S A 2009;106:2824-8.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 2824-2828
    • Boutros, P.C.1    Lau, S.K.2    Pintilie, M.3
  • 31
    • 49149129916 scopus 로고    scopus 로고
    • Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study
    • Director's Challenge Consortium for the Molecular Classification of Lung Adenocarcinoma1, Shedden K, Taylor JM, et al. Gene expression-based survival prediction in lung adenocarcinoma: a multi-site, blinded validation study. Nat Med 2008;14:822-7.
    • (2008) Nat Med , vol.14 , pp. 822-827
    • Shedden, K.1    Taylor, J.M.2
  • 32
    • 78649680251 scopus 로고    scopus 로고
    • Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer
    • Zhu CQ, Ding K, Strumpf D, et al. Prognostic and predictive gene signature for adjuvant chemotherapy in resected non-small-cell lung cancer. J Clin Oncol 2010;28:4417-24.
    • (2010) J Clin Oncol , vol.28 , pp. 4417-4424
    • Zhu, C.Q.1    Ding, K.2    Strumpf, D.3
  • 33
    • 84891830936 scopus 로고    scopus 로고
    • Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients
    • Der SD, Sykes J, Pintilie M, et al. Validation of a histology-independent prognostic gene signature for early-stage, non-small-cell lung cancer including stage IA patients. J Thorac Oncol 2014;9:59-64.
    • (2014) J Thorac Oncol , vol.9 , pp. 59-64
    • Der, S.D.1    Sykes, J.2    Pintilie, M.3
  • 34
    • 84861985508 scopus 로고    scopus 로고
    • A practical molecular assay to predict survival in resected nonsquamous, non-small-cell lung cancer: development and international validation studies
    • Kratz JR, He J, Van Den Eeden SK, et al. A practical molecular assay to predict survival in resected nonsquamous, non-small-cell lung cancer: development and international validation studies. Lancet 2012;379:823-32.
    • (2012) Lancet , vol.379 , pp. 823-832
    • Kratz, J.R.1    He, J.2    Van Den Eeden, S.K.3
  • 35
    • 84863085860 scopus 로고    scopus 로고
    • Genomic signatures for predicting survival and adjuvant chemotherapy benefit in patients with nonsmall-cell lung cancer
    • Van Laar RK. Genomic signatures for predicting survival and adjuvant chemotherapy benefit in patients with nonsmall-cell lung cancer. BMC Med Genomics 2012;5:30.
    • (2012) BMC Med Genomics , vol.5 , pp. 30
    • Van Laar, R.K.1
  • 36
    • 84862848034 scopus 로고    scopus 로고
    • Prognostic and predictive value of a malignancy-risk gene signature in early-stage non-small cell lung cancer
    • Chen DT, Hsu YL, Fulp WJ, et al. Prognostic and predictive value of a malignancy-risk gene signature in early-stage non-small cell lung cancer. J Natl Cancer Inst 2011;103:1859-70.
    • (2011) J Natl Cancer Inst , vol.103 , pp. 1859-1870
    • Chen, D.T.1    Hsu, Y.L.2    Fulp, W.J.3
  • 37
    • 84875152217 scopus 로고    scopus 로고
    • A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients
    • Tang H, Xiao G, Behrens C, et al. A 12-gene set predicts survival benefits from adjuvant chemotherapy in non-small cell lung cancer patients. Clin Cancer Res 2013;19:1577-86.
    • (2013) Clin Cancer Res , vol.19 , pp. 1577-1586
    • Tang, H.1    Xiao, G.2    Behrens, C.3
  • 38
    • 84888087538 scopus 로고    scopus 로고
    • Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma
    • Wistuba II, Behrens C, Lombardi F, et al. Validation of a proliferation-based expression signature as prognostic marker in early stage lung adenocarcinoma. Clin Cancer Res 2013;19:6261-71.
    • (2013) Clin Cancer Res , vol.19 , pp. 6261-6271
    • Wistuba, I.I.1    Behrens, C.2    Lombardi, F.3
  • 39
    • 84867702109 scopus 로고    scopus 로고
    • A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors
    • Kratz JR, Van den Eeden SK, He J, et al. A prognostic assay to identify patients at high risk of mortality despite small, node-negative lung tumors. JAMA 2012;308:1629-31.
    • (2012) JAMA , vol.308 , pp. 1629-1631
    • Kratz, J.R.1    Van den Eeden, S.K.2    He, J.3
  • 40
    • 84879538777 scopus 로고    scopus 로고
    • Molecular prognostication of nonsmall cell lung cancer
    • Tsao MS, Jablons DM. Molecular prognostication of nonsmall cell lung cancer. Semin Thorac Cardiovasc Surg 2013;25:4-7.
    • (2013) Semin Thorac Cardiovasc Surg , vol.25 , pp. 4-7
    • Tsao, M.S.1    Jablons, D.M.2
  • 41
    • 20544455590 scopus 로고    scopus 로고
    • Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer
    • Winton T, Livingston R, Johnson D, et al. Vinorelbine plus cisplatin vs. observation in resected non-small-cell lung cancer. N Engl J Med 2005;352:2589-97.
    • (2005) N Engl J Med , vol.352 , pp. 2589-2597
    • Winton, T.1    Livingston, R.2    Johnson, D.3
  • 42
    • 74849113364 scopus 로고    scopus 로고
    • Proliferative genes dominate malignancy-risk gene signature in histologicallynormal breast tissue
    • Chen DT, Nasir A, Culhane A, et al. Proliferative genes dominate malignancy-risk gene signature in histologicallynormal breast tissue. Breast Cancer Res Treat 2010;119:335-46.
    • (2010) Breast Cancer Res Treat , vol.119 , pp. 335-346
    • Chen, D.T.1    Nasir, A.2    Culhane, A.3
  • 43
    • 67649965344 scopus 로고    scopus 로고
    • Relapserelated molecular signature in lung adenocarcinomas identifies patients with dismal prognosis
    • Tomida S, Takeuchi T, Shimada Y, et al. Relapserelated molecular signature in lung adenocarcinomas identifies patients with dismal prognosis. J Clin Oncol 2009;27:2793-9.
    • (2009) J Clin Oncol , vol.27 , pp. 2793-2799
    • Tomida, S.1    Takeuchi, T.2    Shimada, Y.3
  • 44
    • 31144459985 scopus 로고    scopus 로고
    • Oncogenic pathway signatures in human cancers as a guide to targeted therapies
    • Bild AH, Yao G, Chang JT, et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies. Nature 2006;439:353-7.
    • (2006) Nature , vol.439 , pp. 353-357
    • Bild, A.H.1    Yao, G.2    Chang, J.T.3
  • 45
    • 58149343905 scopus 로고    scopus 로고
    • Prediction of recurrencefree survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression
    • Lee ES, Son DS, Kim SH, et al. Prediction of recurrencefree survival in postoperative non-small cell lung cancer patients by using an integrated model of clinical information and gene expression. Clin Cancer Res 2008;14:7397-404.
    • (2008) Clin Cancer Res , vol.14 , pp. 7397-7404
    • Lee, E.S.1    Son, D.S.2    Kim, S.H.3
  • 46
    • 33645804773 scopus 로고    scopus 로고
    • Expression profiledefined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors
    • Takeuchi T, Tomida S, Yatabe Y, et al. Expression profiledefined classification of lung adenocarcinoma shows close relationship with underlying major genetic changes and clinicopathologic behaviors. J Clin Oncol 2006;24:1679-88.
    • (2006) J Clin Oncol , vol.24 , pp. 1679-1688
    • Takeuchi, T.1    Tomida, S.2    Yatabe, Y.3
  • 47
    • 79952042778 scopus 로고    scopus 로고
    • Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study
    • Cuzick J, Swanson GP, Fisher G, et al. Prognostic value of an RNA expression signature derived from cell cycle proliferation genes in patients with prostate cancer: a retrospective study. Lancet Oncol 2011;12:245-55.
    • (2011) Lancet Oncol , vol.12 , pp. 245-255
    • Cuzick, J.1    Swanson, G.P.2    Fisher, G.3
  • 48
    • 84855369366 scopus 로고    scopus 로고
    • Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas
    • Okayama H, Kohno T, Ishii Y, et al. Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas. Cancer Res 2012;72:100-11.
    • (2012) Cancer Res , vol.72 , pp. 100-111
    • Okayama, H.1    Kohno, T.2    Ishii, Y.3
  • 49
    • 24944497744 scopus 로고    scopus 로고
    • Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib
    • Eberhard DA, Johnson BE, Amler LC, et al. Mutations in the epidermal growth factor receptor and in KRAS are predictive and prognostic indicators in patients with non-small-cell lung cancer treated with chemotherapy alone and in combination with erlotinib. J Clin Oncol 2005;23:5900-9.
    • (2005) J Clin Oncol , vol.23 , pp. 5900-5909
    • Eberhard, D.A.1    Johnson, B.E.2    Amler, L.C.3
  • 50
    • 33846187218 scopus 로고    scopus 로고
    • Update on epidermal growth factor receptor mutations in non-small cell lung cancer
    • Riely GJ, Politi KA, Miller VA, et al. Update on epidermal growth factor receptor mutations in non-small cell lung cancer. Clin Cancer Res 2006;12:7232-41.
    • (2006) Clin Cancer Res , vol.12 , pp. 7232-7241
    • Riely, G.J.1    Politi, K.A.2    Miller, V.A.3
  • 51
    • 27944499351 scopus 로고    scopus 로고
    • EGFR and erbB2 mutation status in Japanese lung cancer patients
    • Sasaki H, Shimizu S, Endo K, et al. EGFR and erbB2 mutation status in Japanese lung cancer patients. Int J Cancer 2006;118:180-4.
    • (2006) Int J Cancer , vol.118 , pp. 180-184
    • Sasaki, H.1    Shimizu, S.2    Endo, K.3
  • 52
    • 61549091557 scopus 로고    scopus 로고
    • Prognostic implication of EGFR, KRAS, and TP53 gene mutations in a large cohort of Japanese patients with surgically treated lung adenocarcinoma
    • Kosaka T, Yatabe Y, Onozato R, et al. Prognostic implication of EGFR, KRAS, and TP53 gene mutations in a large cohort of Japanese patients with surgically treated lung adenocarcinoma. J Thorac Oncol 2009;4:22-9.
    • (2009) J Thorac Oncol , vol.4 , pp. 22-29
    • Kosaka, T.1    Yatabe, Y.2    Onozato, R.3
  • 53
    • 84874888512 scopus 로고    scopus 로고
    • Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer
    • Kim HR, Kim DJ, Kang DR, et al. Fibroblast growth factor receptor 1 gene amplification is associated with poor survival and cigarette smoking dosage in patients with resected squamous cell lung cancer. J Clin Oncol 2013;31:731-7.
    • (2013) J Clin Oncol , vol.31 , pp. 731-737
    • Kim, H.R.1    Kim, D.J.2    Kang, D.R.3
  • 54
    • 67649444188 scopus 로고    scopus 로고
    • Lung cancer xenografting alters microRNA profile but not immunophenotype
    • Bogner PN, Patnaik SK, Pitoniak R, et al. Lung cancer xenografting alters microRNA profile but not immunophenotype. Biochem Biophys Res Commun 2009;386:305-10.
    • (2009) Biochem Biophys Res Commun , vol.386 , pp. 305-310
    • Bogner, P.N.1    Patnaik, S.K.2    Pitoniak, R.3
  • 55
    • 67651002796 scopus 로고    scopus 로고
    • MicroRNA classifiers for predicting prognosis of squamous cell lung cancer
    • Raponi M, Dossey L, Jatkoe T, et al. MicroRNA classifiers for predicting prognosis of squamous cell lung cancer. Cancer Res 2009;69:5776-83.
    • (2009) Cancer Res , vol.69 , pp. 5776-5783
    • Raponi, M.1    Dossey, L.2    Jatkoe, T.3
  • 56
    • 77950498821 scopus 로고    scopus 로고
    • Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer
    • Hu Z, Chen X, Zhao Y, et al. Serum microRNA signatures identified in a genome-wide serum microRNA expression profiling predict survival of non-small-cell lung cancer. J Clin Oncol 2010;28:1721-6.
    • (2010) J Clin Oncol , vol.28 , pp. 1721-1726
    • Hu, Z.1    Chen, X.2    Zhao, Y.3
  • 57
    • 80455173422 scopus 로고    scopus 로고
    • A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsamiR-31 for prognosis
    • Tan X, Qin W, Zhang L, et al. A 5-microRNA signature for lung squamous cell carcinoma diagnosis and hsamiR-31 for prognosis. Clin Cancer Res 2011;17:6802-11.
    • (2011) Clin Cancer Res , vol.17 , pp. 6802-6811
    • Tan, X.1    Qin, W.2    Zhang, L.3
  • 58
    • 78149462073 scopus 로고    scopus 로고
    • Use of microRNA expression levels to predict outcomes in resected stage I non-small cell lung cancer
    • Duncavage E, Goodgame B, Sezhiyan A, et al. Use of microRNA expression levels to predict outcomes in resected stage I non-small cell lung cancer. J Thorac Oncol 2010;5:1755-63.
    • (2010) J Thorac Oncol , vol.5 , pp. 1755-1763
    • Duncavage, E.1    Goodgame, B.2    Sezhiyan, A.3
  • 59
    • 80053023874 scopus 로고    scopus 로고
    • International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary
    • Travis WD, Brambilla E, Noguchi M, et al. International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society: international multidisciplinary classification of lung adenocarcinoma: executive summary. Proc Am Thorac Soc 2011;8:381-5.
    • (2011) Proc Am Thorac Soc , vol.8 , pp. 381-385
    • Travis, W.D.1    Brambilla, E.2    Noguchi, M.3


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