Expression of cyclin D1 but not of cyclin E is an indicator of poor prognosis in small adenocarcinomas of the lung

Oncology Reports

Volumn 10, Issue 1, 2003, Pages 137-139

  Ikehara, Mizuki ^a   Oshita, Fumihiro ^a   Ito, Hiroyuki ^a   Ohgane, Naoki ^a   Suzuki, Rie ^a   Saito, Haruhiro ^a   Yamada, Kouzo ^a   Noda, Kazumasa ^a   Mitsuda, Aki ^a   Kameda, Yoichi ^a  

^a KANAGAWA CANCER CENTER   (Japan)

Author keywords

Adenocarcinoma; Cyclin

Indexed keywords

CYCLIN D1; CYCLIN E; TUMOR MARKER;

ADENOCARCINOMA; ADULT; AGED; ARTICLE; ENZYME IMMUNOASSAY; FEMALE; HUMAN; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PROGNOSIS; SURVIVAL RATE;

ADENOCARCINOMA; ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, NON-SMALL-CELL LUNG; CYCLIN D1; CYCLIN E; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; LUNG NEOPLASMS; MALE; MIDDLE AGED; PROGNOSIS; SURVIVAL RATE; TUMOR MARKERS, BIOLOGICAL;

EID: 0142138047     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.10.1.137     Document Type: Article

References (14)

1. Martini N and Ginsberg R: Treatment of stage I and II disease. In: Comprehensive Textbook of Thoracic Oncology. Aisner J, Arriagada R, Green M, et al (eds). Williams & Williams, Baltimore, MD, pp339-350, 1996.
2. Pines J and Hunter T: Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle for interaction with p34cdc2. Cell 58: 833-846, 1989. (Pubitemid 19227894)
3. Koff A, Giordano A, Desai D, et al: Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257: 1689-1694, 1992.
4. Sherr CJ: Mammmarian Gl cyclins. Cell 73: 1059-1065, 1993.
5. Keyomarsi K, O'Leary N, Molnar G, et al: Cyclin E, a potential prognostic marker for breast cancer. Cancer Res 54: 380-385, 1994. (Pubitemid 24053173)
6. Dutta A, Chandra R, Leiter LM, et al: Cyclins as markers of tumor proliferation: immunohistochemical studies in breast cancer. Proc Natl Acad Sci USA 92: 5386-5390, 1995.
7. Nielsen NH, Arnerl C, Emdin SO, et al: Cyclin E overexpression, a negative prognostic factor in breast cancer with strong correlation to oestrogen receptor status. Br J Cancer 74: 874-880, 1996. (Pubitemid 26319319)
8. Betticher DC, Heighway J, Hasleton PS, et al: Prognostic significance of CCND (cyclin D1) overexpression in primary resected non-small cell lung cancer. Br J Cancer 73: 294-300, 1996. (Pubitemid 26047506)
9. Dosaka-Akita H, Hommura F, Mishina T, et al: A risk-stratification model of non-small cell lung cancers using cyclin E, Ki-67, and ras p21: different roles of G1 cyclins in cell proliferation and prognosis. Cancer Res 61: 2500-2504, 2001. (Pubitemid 32691131)
10. Spruck CH, Won K and Reed SI: Deregulated cyclin E induces chromosome instability. Nature 401: 297-300, 1999.
11. Muller-Tidow C, Metzger R, Kugler K, et al: Cyclin E is the only cyclin-dependent kinase 2-associated cyclin that predicts metastasis and survival in early stage non-small cell lung cancer. Cancer Res 61: 647-653, 2001. (Pubitemid 32128628)
12. Sofer-Levi Y and Resnitzky D: Apoptosis induced by ectopic expression of cyclin D1 but not cyclin E. Oncogene 13: 2431-2437, 1996. (Pubitemid 27026026)
13. Ikehara M, Oshita F, Kameda Y, et al: Expression of survivin correlated with vessel invasion is a marker of poor prognosis in small adenocarcinoma of the lung. Oncol Rep 9: 835-838, 2002.
14. Van Zandwijk N, Smit EF, Krame GWP, et al: Gemcitabine and cisplatin as induction regimen for patients with biopsy-proven stage IIIA N2 non-small cell lung cancer: a phase II study of the European Organization for Research and Treatment of Cancer Lung Cancer Cooperative Group (EORTC 08955). J Clin Oncol 18: 2658-2664, 2000. (Pubitemid 30463547)