Tumor-targeted paclitaxel-loaded folate conjugated poly(ethylene glycol)-poly(l-lactide) microparticles produced by supercritical fluid technology

Journal of Materials Science: Materials in Medicine

Volumn 26, Issue 2, 2015, Pages

  Huang, Xiaobei ^a   Zhang, Yanzhi ^a   Yin, Guangfu ^a   Pu, Ximing ^a   Liao, Xiaoming ^a   Huang, Zhongbing ^a   Chen, Xianchun ^a   Yao, Yadong ^a  

^a SICHUAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

ALIPHATIC COMPOUNDS; CELL CULTURE; DISEASES; EFFLUENT TREATMENT; ETHYLENE GLYCOL; LIGHT SCATTERING; MAMMALS; MOLECULAR BIOLOGY; POLYETHYLENE OXIDES; POLYOLS; SCANNING ELECTRON MICROSCOPY; SUPERCRITICAL FLUIDS; TARGETED DRUG DELIVERY; TUMORS;

BIODEGRADABLE DIBLOCK COPOLYMERS; CONFOCAL LASER SCANNING MICROSCOPE; DYNAMIC LIGHT SCATTERING MEASUREMENT; FLUORESCEIN ISOTHIOCYANATE; RECEPTOR-MEDIATED ENDOCYTOSIS; SOLUTION ENHANCED DISPERSION BY SUPERCRITICAL FLUIDS; SUPERCRITICAL FLUID TECHNOLOGY; TUMOR-TARGETED DRUG DELIVERIES;

POLYETHYLENE GLYCOLS;

COPOLYMER; FLUORESCEIN ISOTHIOCYANATE; FOLATE RECEPTOR; FOLIC ACID; MACROGOL 2000; PACLITAXEL; POLY(ETHYLENE GLYCOL CO LEVO LACTIDE); POLYLACTIDE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; DRUG CARRIER; LACTIC ACID DERIVATIVE; MACROGOL DERIVATIVE; POLY(LACTIC ACID)-BLOCK-POLYETHYLENE GLYCOL-FOLATE; POLY(LACTIC ACID-ETHYLENE GLYCOL); POLYESTER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL ULTRASTRUCTURE; CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACCUMULATION; DRUG CONJUGATION; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG FORMULATION; DRUG TARGETING; DRUG TISSUE LEVEL; DRUG UPTAKE; ENDOCYTOSIS; FEMALE; FIBROBLAST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HYDRODYNAMICS; IN VITRO STUDY; LIGHT SCATTERING; MICROENCAPSULATION; MOLECULARLY TARGETED THERAPY; MOUSE; NONHUMAN; OVARIAN CANCER CELL LINE; PARTICLE SIZE; POLYMERIZATION; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SCANNING ELECTRON MICROSCOPY; SUPERCRITICAL FLUID; TRANSMISSION ELECTRON MICROSCOPY; TUMOR XENOGRAFT; 3T3 CELL LINE; ANIMAL; CELL LINE; CHEMISTRY; DRUG SCREENING; MEDICINAL CHEMISTRY; NUDE MOUSE; SUPERCRITICAL FLUID CHROMATOGRAPHY; SYNTHESIS; TISSUE DISTRIBUTION; TUMOR CELL LINE;

MUS MUSCULUS;

3T3 CELLS; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; CELL LINE; CELL LINE, TUMOR; CHEMISTRY, PHARMACEUTICAL; CHROMATOGRAPHY, SUPERCRITICAL FLUID; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; LACTATES; MICE; MICE, NUDE; MICROSCOPY, ELECTRON, SCANNING; MICROSCOPY, ELECTRON, TRANSMISSION; PACLITAXEL; PARTICLE SIZE; POLYESTERS; POLYETHYLENE GLYCOLS; TISSUE DISTRIBUTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84924778105     PISSN: 09574530     EISSN: 15734838     Source Type: Journal    
DOI: 10.1007/s10856-015-5447-x     Document Type: Article

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