Structural characterization of substrate and inhibitor binding to farnesyl pyrophosphate synthase from Pseudomonas aeruginosa

Acta Crystallographica Section D: Biological Crystallography

Volumn 71, Issue , 2015, Pages 721-731

  Schmidberger, Jason W ^a   Schnell, Robert ^a   Schneider, Gunter ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

enzyme assay; enzyme inhibitor; farnesyl pyrophosphate synthase; isoprenoid biosynthesis; ligand complexes; Pseudomonas aeruginosa

Indexed keywords

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; EUKARYOTA; PROKARYOTA; PSEUDOMONAS AERUGINOSA;

BACTERIAL PROTEIN; BISPHOSPHONIC ACID DERIVATIVE; ENZYME INHIBITOR; GERANYLTRANSFERASE; IBANDRONIC ACID;

ANTAGONISTS AND INHIBITORS; CHEMISTRY; ENZYMOLOGY; PROTEIN SECONDARY STRUCTURE; PROTEIN TERTIARY STRUCTURE; PSEUDOMONAS AERUGINOSA; X RAY CRYSTALLOGRAPHY;

BACTERIAL PROTEINS; CRYSTALLOGRAPHY, X-RAY; DIPHOSPHONATES; ENZYME INHIBITORS; GERANYLTRANSTRANSFERASE; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; PSEUDOMONAS AERUGINOSA;

EID: 84924769494     PISSN: 09074449     EISSN: 13990047     Source Type: Journal    
DOI: 10.1107/S1399004715001121     Document Type: Article

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