Glucocorticoids exert direct toxicity on microvasculature: Analysis of cell death mechanisms

Toxicological Sciences

Volumn 143, Issue 2, 2015, Pages 441-453

  El Zaoui, Ikram ^a,b,c   Behar Cohen, Francine ^a,b,c,d   Torriglia, Alicia ^a,b,c  

^a CENTRE DE RECHERCHE DES CORDELIERS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c UNIVERSITÉ PARIS DESCARTES   (France)

^d HÔPITAL OPHTALMIQUE JULES GONIN   (Switzerland)

Author keywords

Apoptosis; Dermic endothelial cell; Endothelial cell; Glucocorticoids; Retinal microvasculature

Indexed keywords

DEOXYRIBONUCLEASE II; DEXAMETHASONE; DEXAMETHASONE SODIUM PHOSPHATE; HYDROCORTISONE; TRIAMCINOLONE ACETONIDE; GLUCOCORTICOID;

ANIMAL CELL; ARTICLE; AUTOPHAGY; BOVINAE; CELL DEATH; CONTROLLED STUDY; DNA DEGRADATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME INHIBITION; HUMAN; HUMAN CELL; MALE; MICROVASCULATURE; NONHUMAN; RAT; RETINA CELL; SKIN CELL; TOXICITY; ANIMAL; BOVINE; CELL NUCLEUS; CELL SURVIVAL; CYTOPLASM; DNA FRAGMENTATION; DOSE RESPONSE; DRUG EFFECTS; LD50; LEWIS RAT; PATHOLOGY; RETINA BLOOD VESSEL; SKIN; ULTRASTRUCTURE; VASCULAR ENDOTHELIUM; VASCULARIZATION;

BOVINAE; RATTUS;

ANIMALS; AUTOPHAGY; CATTLE; CELL NUCLEUS; CELL SURVIVAL; CYTOPLASM; DNA FRAGMENTATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENDOTHELIUM, VASCULAR; GLUCOCORTICOIDS; HUMANS; LETHAL DOSE 50; MALE; MICROVESSELS; RATS; RATS, INBRED LEW; RETINAL VESSELS; SKIN;

EID: 84924733357     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfu243     Document Type: Article

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