Conformational modification of serpins transforms leukocyte elastase inhibitor into an endonuclease involved in apoptosis

Molecular and Cellular Biology

Volumn 27, Issue 11, 2007, Pages 4028-4036

  Padron Barthe, Laura ^a   Leprêtre, Chloé ^a   Martin, Elisabeth ^a   Counis, Marie France ^a   Torriglia, Alicia ^a  

^a INSERM   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ENDONUCLEASE; LEUKOCYTE ELASTASE INHIBITOR; SERINE PROTEINASE INHIBITOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL FATE; CONFORMATION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN MODIFICATION;

ALPHA KARYOPHERINS; AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; CELL LINE; CRICETINAE; ENDODEOXYRIBONUCLEASES; HUMANS; LEUKOCYTE ELASTASE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; NUCLEAR LOCALIZATION SIGNALS; PROTEIN CONFORMATION; SEQUENCE ALIGNMENT; SERPINS; SWINE;

EID: 34347355478     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.01959-06     Document Type: Article

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