메뉴 건너뛰기




Volumn 31, Issue 3, 2015, Pages 100-108

The past, present, and future of Leishmania genomics and transcriptomics

Author keywords

Bioinformatics; Genome; High throughput sequencing; Host parasite interactions; Leishmania infantum; Leishmaniases; Metazoonosis; One Health; Sand fly; Transcriptome

Indexed keywords

ANEUPLOIDY; COPY NUMBER VARIATION; DEVELOPING COUNTRY; GENE EXPRESSION; GENOMICS; HOST PARASITE INTERACTION; HUMAN; IN VITRO STUDY; INFECTION CONTROL; LEISHMANIA; LEISHMANIASIS; NONHUMAN; PARASITE SURVIVAL; PARASITE VECTOR; REVIEW; SINGLE NUCLEOTIDE POLYMORPHISM; TRANSCRIPTOMICS; TUNGA; ANIMAL; GENE EXPRESSION PROFILING; GENETICS; GENOME; METABOLISM; TRENDS;

EID: 84924715788     PISSN: 14714922     EISSN: 14715007     Source Type: Journal    
DOI: 10.1016/j.pt.2014.12.012     Document Type: Review
Times cited : (79)

References (71)
  • 1
    • 84861665791 scopus 로고    scopus 로고
    • Leishmaniasis worldwide and global estimates of its incidence
    • Alvar J., et al. Leishmaniasis worldwide and global estimates of its incidence. PLoS ONE 2012, 7:e35671.
    • (2012) PLoS ONE , vol.7 , pp. e35671
    • Alvar, J.1
  • 2
    • 84873811150 scopus 로고    scopus 로고
    • Biology of phlebotomine sand flies as vectors of disease agents
    • Ready P.D. Biology of phlebotomine sand flies as vectors of disease agents. Annu. Rev. Entomol. 2013, 58:227-250.
    • (2013) Annu. Rev. Entomol. , vol.58 , pp. 227-250
    • Ready, P.D.1
  • 3
    • 84879463480 scopus 로고    scopus 로고
    • The prevention of canine leishmaniasis and its impact on public health
    • Otranto D., Dantas-Torres F. The prevention of canine leishmaniasis and its impact on public health. Trends Parasitol. 2013, 29:339-345.
    • (2013) Trends Parasitol. , vol.29 , pp. 339-345
    • Otranto, D.1    Dantas-Torres, F.2
  • 4
    • 84903464772 scopus 로고    scopus 로고
    • Determinants of disease phenotype in trypanosomatid parasites
    • McCall L.I., McKerrow J.H. Determinants of disease phenotype in trypanosomatid parasites. Trends Parasitol. 2014, 30:342-349.
    • (2014) Trends Parasitol. , vol.30 , pp. 342-349
    • McCall, L.I.1    McKerrow, J.H.2
  • 5
    • 84901805285 scopus 로고    scopus 로고
    • Comparative analysis of the omics technologies used to study antimonial, amphotericin B, and pentamidine resistance in Leishmania
    • Kaur G., Rajput B. Comparative analysis of the omics technologies used to study antimonial, amphotericin B, and pentamidine resistance in Leishmania. J. Parasitol. Res. 2014, 2014:726328.
    • (2014) J. Parasitol. Res. , vol.2014 , pp. 726328
    • Kaur, G.1    Rajput, B.2
  • 6
    • 84904999159 scopus 로고    scopus 로고
    • Neglected tropical diseases and omics science: proteogenomics analysis of the promastigote stage of Leishmania major parasite
    • Pawar H., et al. Neglected tropical diseases and omics science: proteogenomics analysis of the promastigote stage of Leishmania major parasite. OMICS 2014, 18:499-512.
    • (2014) OMICS , vol.18 , pp. 499-512
    • Pawar, H.1
  • 7
    • 84924723054 scopus 로고    scopus 로고
    • Leishmania genomics: where do we stand?
    • National Library of Medicine, National Center for Biotechnology Information, Chapter B02, A. Gruber (Ed.)
    • Uliana S.R.B., et al. Leishmania genomics: where do we stand?. Bioinformatics in Tropical Disease Research: A Practical and Case-Study Approach 2008, National Library of Medicine, National Center for Biotechnology Information, Chapter B02. A. Gruber (Ed.).
    • (2008) Bioinformatics in Tropical Disease Research: A Practical and Case-Study Approach
    • Uliana, S.R.B.1
  • 8
    • 22244437571 scopus 로고    scopus 로고
    • The genome of the kinetoplastid parasite, Leishmania major
    • Ivens A.C., et al. The genome of the kinetoplastid parasite, Leishmania major. Science 2005, 309:436-442.
    • (2005) Science , vol.309 , pp. 436-442
    • Ivens, A.C.1
  • 9
    • 34347339518 scopus 로고    scopus 로고
    • Comparative genomic analysis of three Leishmania species that cause diverse human disease
    • Peacock C.S., et al. Comparative genomic analysis of three Leishmania species that cause diverse human disease. Nat. Genet. 2007, 39:839-847.
    • (2007) Nat. Genet. , vol.39 , pp. 839-847
    • Peacock, C.S.1
  • 10
    • 83055181962 scopus 로고    scopus 로고
    • Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania
    • Rogers M.B., et al. Chromosome and gene copy number variation allow major structural change between species and strains of Leishmania. Genome Res. 2011, 21:2129-2142.
    • (2011) Genome Res. , vol.21 , pp. 2129-2142
    • Rogers, M.B.1
  • 11
    • 83055168329 scopus 로고    scopus 로고
    • Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance
    • Downing T., et al. Whole genome sequencing of multiple Leishmania donovani clinical isolates provides insights into population structure and mechanisms of drug resistance. Genome Res. 2011, 21:2143-2156.
    • (2011) Genome Res. , vol.21 , pp. 2143-2156
    • Downing, T.1
  • 12
    • 84890466311 scopus 로고    scopus 로고
    • The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene models
    • Real F., et al. The genome sequence of Leishmania (Leishmania) amazonensis: functional annotation and extended analysis of gene models. DNA Res. 2013, 20:567-581.
    • (2013) DNA Res. , vol.20 , pp. 567-581
    • Real, F.1
  • 13
    • 77954375566 scopus 로고    scopus 로고
    • Screening Leishmania donovani-specific genes required for visceral infection
    • Zhang W.W., Matlashewski G. Screening Leishmania donovani-specific genes required for visceral infection. Mol. Microbiol. 2010, 77:505-517.
    • (2010) Mol. Microbiol. , vol.77 , pp. 505-517
    • Zhang, W.W.1    Matlashewski, G.2
  • 14
    • 0041315545 scopus 로고    scopus 로고
    • Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection
    • Zhang W.W., et al. Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection. J. Biol. Chem. 2003, 35508-35515.
    • (2003) J. Biol. Chem. , pp. 35508-35515
    • Zhang, W.W.1
  • 15
    • 84905365168 scopus 로고    scopus 로고
    • Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain
    • Zhang W.W., et al. Genetic analysis of Leishmania donovani tropism using a naturally attenuated cutaneous strain. PLoS Pathog. 2014, 10:e1004244.
    • (2014) PLoS Pathog. , vol.10 , pp. e1004244
    • Zhang, W.W.1
  • 16
    • 34447271391 scopus 로고    scopus 로고
    • Global gene expression in Leishmania
    • Cohen-Freue G., et al. Global gene expression in Leishmania. Int. J. Parasitol. 2007, 37:1077-1086.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 1077-1086
    • Cohen-Freue, G.1
  • 17
    • 0037836064 scopus 로고    scopus 로고
    • Evaluation of differential gene expression in Leishmania major Friedlin procyclics and metacyclics using DNA microarray analysis
    • Saxena A., et al. Evaluation of differential gene expression in Leishmania major Friedlin procyclics and metacyclics using DNA microarray analysis. Mol. Biochem. Parasitol. 2007, 129:103-114.
    • (2007) Mol. Biochem. Parasitol. , vol.129 , pp. 103-114
    • Saxena, A.1
  • 18
    • 77957751346 scopus 로고    scopus 로고
    • Transcriptomics throughout the life cycle of Leishmania infantum: high down-regulation rate in the amastigote stage
    • Alcolea P.J., et al. Transcriptomics throughout the life cycle of Leishmania infantum: high down-regulation rate in the amastigote stage. Int. J. Parasitol. 2010, 40:1497-1516.
    • (2010) Int. J. Parasitol. , vol.40 , pp. 1497-1516
    • Alcolea, P.J.1
  • 19
    • 84875689170 scopus 로고    scopus 로고
    • The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-Seq
    • Rastrojo A., et al. The transcriptome of Leishmania major in the axenic promastigote stage: transcript annotation and relative expression levels by RNA-Seq. BMC Genomics 2013, 14:223.
    • (2013) BMC Genomics , vol.14 , pp. 223
    • Rastrojo, A.1
  • 20
    • 84902033196 scopus 로고    scopus 로고
    • A dual luciferase system for analysis of post-transcriptional regulation of gene expression in Leishmania
    • Soysa R., et al. A dual luciferase system for analysis of post-transcriptional regulation of gene expression in Leishmania. Mol. Biochem. Parasitol. 2014, 195:1-5.
    • (2014) Mol. Biochem. Parasitol. , vol.195 , pp. 1-5
    • Soysa, R.1
  • 21
    • 79959747779 scopus 로고    scopus 로고
    • Lights and shadows on gene organization and regulation of gene expression in Leishmania
    • Requena J.M. Lights and shadows on gene organization and regulation of gene expression in Leishmania. Front. Biosci. 2011, 16:2069-2085.
    • (2011) Front. Biosci. , vol.16 , pp. 2069-2085
    • Requena, J.M.1
  • 22
    • 84867077750 scopus 로고    scopus 로고
    • Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania
    • Sterkers Y., et al. Novel insights into genome plasticity in Eukaryotes: mosaic aneuploidy in Leishmania. Mol. Microbiol. 2012, 86:15-23.
    • (2012) Mol. Microbiol. , vol.86 , pp. 15-23
    • Sterkers, Y.1
  • 23
    • 84883896199 scopus 로고    scopus 로고
    • A transcriptomic network identified in uninfected macrophages responding to inflammation control intracellular pathogen survival
    • Beattie L., et al. A transcriptomic network identified in uninfected macrophages responding to inflammation control intracellular pathogen survival. Cell Host Microbe 2013, 14:357-368.
    • (2013) Cell Host Microbe , vol.14 , pp. 357-368
    • Beattie, L.1
  • 24
    • 84866946835 scopus 로고    scopus 로고
    • Transcriptome patterns from primary cutaneous Leishmania braziliensis infections associated with eventual development of mucosal disease in humans
    • Maretti-Mira A.C., et al. Transcriptome patterns from primary cutaneous Leishmania braziliensis infections associated with eventual development of mucosal disease in humans. PLoS Negl. Trop. Dis. 2012, 6:e1816.
    • (2012) PLoS Negl. Trop. Dis. , vol.6 , pp. e1816
    • Maretti-Mira, A.C.1
  • 25
    • 40749112352 scopus 로고    scopus 로고
    • Comparison of the effects of Leishmania major or Leishmania donovani infection on macrophage gene expression
    • Gregory D.J., et al. Comparison of the effects of Leishmania major or Leishmania donovani infection on macrophage gene expression. Infect. Immun. 2008, 76:1186-1192.
    • (2008) Infect. Immun. , vol.76 , pp. 1186-1192
    • Gregory, D.J.1
  • 26
    • 84908158281 scopus 로고    scopus 로고
    • Leishmania molecules that mediate intracellular pathogenesis
    • Kima P.E. Leishmania molecules that mediate intracellular pathogenesis. Microbes Infect. 2014, 16:721-726.
    • (2014) Microbes Infect. , vol.16 , pp. 721-726
    • Kima, P.E.1
  • 27
    • 59249089702 scopus 로고    scopus 로고
    • Sand flies, Leishmania, and transcriptome-borne solutions
    • Oliveira F., et al. Sand flies, Leishmania, and transcriptome-borne solutions. Parasitol. Int. 2009, 58:1-5.
    • (2009) Parasitol. Int. , vol.58 , pp. 1-5
    • Oliveira, F.1
  • 28
    • 64849083163 scopus 로고    scopus 로고
    • Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector
    • Akopyants N.S., et al. Demonstration of genetic exchange during cyclical development of Leishmania in the sand fly vector. Science 2009, 324:265-268.
    • (2009) Science , vol.324 , pp. 265-268
    • Akopyants, N.S.1
  • 29
    • 84880764832 scopus 로고    scopus 로고
    • The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectors
    • Inbar E., et al. The mating competence of geographically diverse Leishmania major strains in their natural and unnatural sand fly vectors. PLoS Genet. 2013, 9:e1003672.
    • (2013) PLoS Genet. , vol.9 , pp. e1003672
    • Inbar, E.1
  • 30
    • 84907584462 scopus 로고    scopus 로고
    • First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones
    • Calvo-Alvarez E., et al. First evidence of intraclonal genetic exchange in trypanosomatids using two Leishmania infantum fluorescent transgenic clones. PLoS Negl. Trop. Dis. 2014, 8:e3075.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , pp. e3075
    • Calvo-Alvarez, E.1
  • 31
    • 33749257454 scopus 로고    scopus 로고
    • First report of genetic hybrids between two very divergent Leishmania species: Leishmania infantum and Leishmania major
    • Ravel C., et al. First report of genetic hybrids between two very divergent Leishmania species: Leishmania infantum and Leishmania major. Int. J. Parasitol. 2006, 36:1383-1388.
    • (2006) Int. J. Parasitol. , vol.36 , pp. 1383-1388
    • Ravel, C.1
  • 32
    • 33947304638 scopus 로고    scopus 로고
    • Increased transmission potential of Leishmania major/Leishmania infantum hybrids
    • Volf P., et al. Increased transmission potential of Leishmania major/Leishmania infantum hybrids. Int. J. Parasitol. 2007, 37:589-593.
    • (2007) Int. J. Parasitol. , vol.37 , pp. 589-593
    • Volf, P.1
  • 33
    • 35349003712 scopus 로고    scopus 로고
    • Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected sandflies
    • Ramalho-Ortigao M., et al. Exploring the midgut transcriptome of Phlebotomus papatasi: comparative analysis of expression profiles of sugar-fed, blood-fed and Leishmania major-infected sandflies. BMC Genomics 2007, 8:300.
    • (2007) BMC Genomics , vol.8 , pp. 300
    • Ramalho-Ortigao, M.1
  • 34
    • 39749132941 scopus 로고    scopus 로고
    • The midgut transcriptome of Lutzomyia longipalpis: comparative analysis of cDNA libraries from sugar-fed, blood-fed, post-digested and Leishmania infantum-chagasi-infected sand flies
    • Jochim R.C., et al. The midgut transcriptome of Lutzomyia longipalpis: comparative analysis of cDNA libraries from sugar-fed, blood-fed, post-digested and Leishmania infantum-chagasi-infected sand flies. BMC Genomics 2008, 9:15.
    • (2008) BMC Genomics , vol.9 , pp. 15
    • Jochim, R.C.1
  • 35
    • 0030756551 scopus 로고    scopus 로고
    • A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut
    • Pimenta P.F., et al. A novel role for the peritrophic matrix in protecting Leishmania from the hydrolytic activities of the sand fly midgut. Parasitology 1997, 115:359-369.
    • (1997) Parasitology , vol.115 , pp. 359-369
    • Pimenta, P.F.1
  • 36
    • 68449094959 scopus 로고    scopus 로고
    • Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development
    • Sadlova J., Volf P. Peritrophic matrix of Phlebotomus duboscqi and its kinetics during Leishmania major development. Cell Tissue Res. 2009, 337:313-325.
    • (2009) Cell Tissue Res. , vol.337 , pp. 313-325
    • Sadlova, J.1    Volf, P.2
  • 37
    • 84871772197 scopus 로고    scopus 로고
    • Leishmania development in sand flies: parasites-vector interactions overview
    • Dostalova A., Volf P. Leishmania development in sand flies: parasites-vector interactions overview. Parasit. Vectors 2012, 5:276.
    • (2012) Parasit. Vectors , vol.5 , pp. 276
    • Dostalova, A.1    Volf, P.2
  • 38
    • 78149231890 scopus 로고    scopus 로고
    • The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi
    • Sadlova J., et al. The stage-regulated HASPB and SHERP proteins are essential for differentiation of the protozoan parasite Leishmania major in its sand fly vector, Phlebotomus papatasi. Cell Microbiol. 2010, 12:1765-1779.
    • (2010) Cell Microbiol. , vol.12 , pp. 1765-1779
    • Sadlova, J.1
  • 39
    • 84876666678 scopus 로고    scopus 로고
    • Characterization of the biology and infectivity of Leishmania infantum viscerotropic and dermotropic strains isolated from HIV+ and HIV- patients in the murine model of visceral leishmaniasis
    • Cunha J., et al. Characterization of the biology and infectivity of Leishmania infantum viscerotropic and dermotropic strains isolated from HIV+ and HIV- patients in the murine model of visceral leishmaniasis. Parasit. Vectors 2013, 6:122.
    • (2013) Parasit. Vectors , vol.6 , pp. 122
    • Cunha, J.1
  • 40
    • 84903468974 scopus 로고    scopus 로고
    • Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses
    • Dacher M., et al. Probing druggability and biological function of essential proteins in Leishmania combining facilitated null mutant and plasmid shuffle analyses. Mol. Microbiol. 2014, 93:146-166.
    • (2014) Mol. Microbiol. , vol.93 , pp. 146-166
    • Dacher, M.1
  • 41
    • 84893803160 scopus 로고    scopus 로고
    • LmaPA2G4, a homolog of human Ebp1, is an essential gene and inhibits cell proliferation in L. major
    • Norris-Mullins B., et al. LmaPA2G4, a homolog of human Ebp1, is an essential gene and inhibits cell proliferation in L. major. PLoS Negl. Trop. Dis. 2014, 8:e2646.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , pp. e2646
    • Norris-Mullins, B.1
  • 42
    • 79955721624 scopus 로고    scopus 로고
    • The midgut transcriptome of Phlebotomus (Larroussius) perniciosus, a vector of Leishmania infantum: comparison of sugar fed and blood fed sand flies
    • Dostalova A., et al. The midgut transcriptome of Phlebotomus (Larroussius) perniciosus, a vector of Leishmania infantum: comparison of sugar fed and blood fed sand flies. BMC Genomics 2011, 12:223.
    • (2011) BMC Genomics , vol.12 , pp. 223
    • Dostalova, A.1
  • 43
    • 84863648527 scopus 로고    scopus 로고
    • Salivary gland transcriptomes and proteomes of Phlebotomus tobbi and Phlebotomus sergenti, vectors of leishmaniasis
    • Rohousova I., et al. Salivary gland transcriptomes and proteomes of Phlebotomus tobbi and Phlebotomus sergenti, vectors of leishmaniasis. PLoS Negl. Trop. Dis. 2012, 6:e1660.
    • (2012) PLoS Negl. Trop. Dis. , vol.6 , pp. e1660
    • Rohousova, I.1
  • 44
    • 84870289003 scopus 로고    scopus 로고
    • Analysis of salivary gland transcripts of the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis
    • Kato H., et al. Analysis of salivary gland transcripts of the sand fly Lutzomyia ayacuchensis, a vector of Andean-type cutaneous leishmaniasis. Infect. Genet. Evol. 2013, 13:56-66.
    • (2013) Infect. Genet. Evol. , vol.13 , pp. 56-66
    • Kato, H.1
  • 45
    • 84895772502 scopus 로고    scopus 로고
    • Comparative analysis of salivary gland transcriptomes of Phlebotomus orientalis sand flies from endemic and non-endemic foci of visceral leishmaniosis
    • Vlkova M., et al. Comparative analysis of salivary gland transcriptomes of Phlebotomus orientalis sand flies from endemic and non-endemic foci of visceral leishmaniosis. PLoS Negl. Trop. Dis. 2014, 8:e2709.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , pp. e2709
    • Vlkova, M.1
  • 46
    • 67949089655 scopus 로고    scopus 로고
    • Analysis of salivary transcripts and antigens of the sand fly Phlebotomus arabicus
    • Hostomska J., et al. Analysis of salivary transcripts and antigens of the sand fly Phlebotomus arabicus. BMC Genomics 2009, 10:282.
    • (2009) BMC Genomics , vol.10 , pp. 282
    • Hostomska, J.1
  • 47
    • 84895729395 scopus 로고    scopus 로고
    • Lundep, a sand fly salivary endonuclease increases Leishmania parasite survival in neutrophils and inhibits XIIa contact activation in human plasma
    • Chagas A.C., et al. Lundep, a sand fly salivary endonuclease increases Leishmania parasite survival in neutrophils and inhibits XIIa contact activation in human plasma. PLoS Pathog. 2014, 10:e1003923.
    • (2014) PLoS Pathog. , vol.10 , pp. e1003923
    • Chagas, A.C.1
  • 48
    • 84876438840 scopus 로고    scopus 로고
    • Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans
    • Abdeladhim M., et al. Updating the salivary gland transcriptome of Phlebotomus papatasi (Tunisian strain): the search for sand fly-secreted immunogenic proteins for humans. PLoS ONE 2012, 7:e47347.
    • (2012) PLoS ONE , vol.7 , pp. e47347
    • Abdeladhim, M.1
  • 49
    • 84874649867 scopus 로고    scopus 로고
    • The characterisation of the Phlebotomus papatasi transcriptome
    • Abrudan J., et al. The characterisation of the Phlebotomus papatasi transcriptome. Insect Mol. Biol. 2013, 22:211-232.
    • (2013) Insect Mol. Biol. , vol.22 , pp. 211-232
    • Abrudan, J.1
  • 50
    • 84878519442 scopus 로고    scopus 로고
    • Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection
    • de Moura T.R., et al. Functional transcriptomics of wild-caught Lutzomyia intermedia salivary glands: identification of a protective salivary protein against Leishmania braziliensis infection. PLoS Negl. Trop. Dis. 2013, 7:e2242.
    • (2013) PLoS Negl. Trop. Dis. , vol.7 , pp. e2242
    • de Moura, T.R.1
  • 51
    • 84890392430 scopus 로고    scopus 로고
    • Sand-fly saliva-Leishmania-man: the trigger trio
    • Oliveira F., et al. Sand-fly saliva-Leishmania-man: the trigger trio. Front. Immunol. 2013, 4:375.
    • (2013) Front. Immunol. , vol.4 , pp. 375
    • Oliveira, F.1
  • 52
    • 80052355010 scopus 로고    scopus 로고
    • Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burdens in neutrophils
    • Prates D.B., et al. Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burdens in neutrophils. J. Leukoc. Biol. 2011, 90:575-582.
    • (2011) J. Leukoc. Biol. , vol.90 , pp. 575-582
    • Prates, D.B.1
  • 53
    • 8444241618 scopus 로고    scopus 로고
    • Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi
    • Valenzuela J.G., et al. Identification of the most abundant secreted proteins from the salivary glands of the sand fly Lutzomyia longipalpis, vector of Leishmania chagasi. J. Exp. Biol. 2004, 207:3717-3729.
    • (2004) J. Exp. Biol. , vol.207 , pp. 3717-3729
    • Valenzuela, J.G.1
  • 54
    • 84869155767 scopus 로고    scopus 로고
    • Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences
    • Dantas-Torres F., et al. Canine leishmaniosis in the Old and New Worlds: unveiled similarities and differences. Trends Parasitol. 2012, 28:531-538.
    • (2012) Trends Parasitol. , vol.28 , pp. 531-538
    • Dantas-Torres, F.1
  • 55
    • 0028782112 scopus 로고
    • Saliva of Lutzomyia longipalpis sibling species differs in its composition and capacity to enhance leishmaniasis
    • Warburg A., et al. Saliva of Lutzomyia longipalpis sibling species differs in its composition and capacity to enhance leishmaniasis. Philos. Trans. R. Soc. Lond. B: Biol. Sci. 1994, 345:223-230.
    • (1994) Philos. Trans. R. Soc. Lond. B: Biol. Sci. , vol.345 , pp. 223-230
    • Warburg, A.1
  • 56
    • 80055067850 scopus 로고    scopus 로고
    • Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission
    • Vlkova M., et al. Canine antibody response to Phlebotomus perniciosus bites negatively correlates with the risk of Leishmania infantum transmission. PLoS Negl. Trop. Dis. 2011, 5:e1344.
    • (2011) PLoS Negl. Trop. Dis. , vol.5 , pp. e1344
    • Vlkova, M.1
  • 57
    • 84893773834 scopus 로고    scopus 로고
    • Recombinant antigens from Phlebotomus perniciosus saliva as markers of canine exposure to visceral leishmaniases vector
    • Drahota J., et al. Recombinant antigens from Phlebotomus perniciosus saliva as markers of canine exposure to visceral leishmaniases vector. PLoS Negl. Trop. Dis. 2014, 8:e2597.
    • (2014) PLoS Negl. Trop. Dis. , vol.8 , pp. e2597
    • Drahota, J.1
  • 58
    • 84857506160 scopus 로고    scopus 로고
    • Key strongylid nematodes of animals: impact of next-generation transcriptomics on systems biology and biotechnology
    • Cantacessi C., et al. Key strongylid nematodes of animals: impact of next-generation transcriptomics on systems biology and biotechnology. Biotechnol. Adv. 2012, 30:469-488.
    • (2012) Biotechnol. Adv. , vol.30 , pp. 469-488
    • Cantacessi, C.1
  • 59
    • 83455205862 scopus 로고    scopus 로고
    • Mosquito genomics: progress and challenges
    • Severson D.W., Behura S.K. Mosquito genomics: progress and challenges. Annu. Rev. Entomol. 2012, 57:143-166.
    • (2012) Annu. Rev. Entomol. , vol.57 , pp. 143-166
    • Severson, D.W.1    Behura, S.K.2
  • 60
    • 0034176536 scopus 로고    scopus 로고
    • Phylogenetic relationships of phlebotomine sandflies inferred from small subunit nuclear ribosomal DNA
    • Aransay A.M., et al. Phylogenetic relationships of phlebotomine sandflies inferred from small subunit nuclear ribosomal DNA. Insect Mol. Biol. 2000, 9:157-168.
    • (2000) Insect Mol. Biol. , vol.9 , pp. 157-168
    • Aransay, A.M.1
  • 62
    • 84875965986 scopus 로고    scopus 로고
    • Experimental infection of dogs with Leishmania and saliva as a model to study canine visceral leishmaniasis
    • Costa D.J., et al. Experimental infection of dogs with Leishmania and saliva as a model to study canine visceral leishmaniasis. PLoS ONE 2013, 8:e60535.
    • (2013) PLoS ONE , vol.8 , pp. e60535
    • Costa, D.J.1
  • 64
    • 84876071713 scopus 로고    scopus 로고
    • Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains
    • Pratlong F., et al. Geographical distribution and epidemiological features of Old World Leishmania infantum and Leishmania donovani foci, based on the isoenzyme analysis of 2277 strains. Parasitology 2013, 140:423-434.
    • (2013) Parasitology , vol.140 , pp. 423-434
    • Pratlong, F.1
  • 65
    • 65949084697 scopus 로고    scopus 로고
    • Canine leishmaniosis in South America
    • Dantas-Torres F. Canine leishmaniosis in South America. Parasit. Vectors 2009, 2(Suppl. 1):S1.
    • (2009) Parasit. Vectors , vol.2 , pp. S1
    • Dantas-Torres, F.1
  • 66
    • 84902155712 scopus 로고    scopus 로고
    • Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus
    • Baneth G., et al. Mucocutaneous Leishmania tropica infection in a dog from a human cutaneous leishmaniasis focus. Parasit. Vectors 2014, 7:118.
    • (2014) Parasit. Vectors , vol.7 , pp. 118
    • Baneth, G.1
  • 67
    • 0023020425 scopus 로고
    • Leishmania infecting man and wild animals in Saudi Arabia. 2. Leishmania arabica n. sp
    • Peters W., et al. Leishmania infecting man and wild animals in Saudi Arabia. 2. Leishmania arabica n. sp. Trans. R. Soc. Trop. Med. Hyg. 1986, 80:497-502.
    • (1986) Trans. R. Soc. Trop. Med. Hyg. , vol.80 , pp. 497-502
    • Peters, W.1
  • 68
    • 0026851667 scopus 로고
    • Description of Leishmania equatorensis sp. n (Kinetoplastida: Trypanosomatidae), a new parasite infecting arboreal mammals in Ecuador
    • Grimaldi Júnior G., et al. Description of Leishmania equatorensis sp. n (Kinetoplastida: Trypanosomatidae), a new parasite infecting arboreal mammals in Ecuador. Mem. Inst. Oswaldo Cruz 1992, 87:221-228.
    • (1992) Mem. Inst. Oswaldo Cruz , vol.87 , pp. 221-228
    • Grimaldi Júnior, G.1
  • 69
    • 0242271971 scopus 로고    scopus 로고
    • Leishmania (Viannia) utingensis n. sp., a parasite from the sandfly Lutzomyia (Viannamyia) tuberculata in Amazonian Brazil
    • Braga R.R., et al. Leishmania (Viannia) utingensis n. sp., a parasite from the sandfly Lutzomyia (Viannamyia) tuberculata in Amazonian Brazil. Parasite 2003, 10:111-118.
    • (2003) Parasite , vol.10 , pp. 111-118
    • Braga, R.R.1
  • 70
    • 84879545389 scopus 로고    scopus 로고
    • Genetic structure and evolution of the Leishmania genus in Africa and Eurasia: what does MLSA tell us
    • El Baidouri F., et al. Genetic structure and evolution of the Leishmania genus in Africa and Eurasia: what does MLSA tell us. PLoS Negl. Trop. Dis. 2013, 7:e2255.
    • (2013) PLoS Negl. Trop. Dis. , vol.7 , pp. e2255
    • El Baidouri, F.1
  • 71
    • 56149104883 scopus 로고    scopus 로고
    • Hyaluronidase of bloodsucking insects and its enhancing effect on Leishmania infection in mice
    • Volfova V., et al. Hyaluronidase of bloodsucking insects and its enhancing effect on Leishmania infection in mice. PLoS Negl. Trop. Dis. 2008, 2:e294.
    • (2008) PLoS Negl. Trop. Dis. , vol.2 , pp. e294
    • Volfova, V.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.