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Volumn 9, Issue 8, 2014, Pages

Psychedelic N,N-dimethyltryptamine and 5-methoxy-N,N-dimethyltryptamine modulate innate and adaptive inflammatory responses through the sigma-1 receptor of human monocyte-derived dendritic cells

Author keywords

[No Author keywords available]

Indexed keywords

1 PHENYLCYCLOHEXANECARBOXYLIC ACID 2 MORPHOLINOETHYL ESTER; 5 METHOXY N,N DIMETHYLTRYPTAMINE; INTERLEUKIN 10; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPOLYSACCHARIDE; N,N DIMETHYLTRYPTAMINE; POLYINOSINIC POLYCYTIDYLIC ACID; PSYCHEDELIC AGENT; SIGMA 1 OPIATE RECEPTOR; TUMOR NECROSIS FACTOR ALPHA; 2-(4-MORPHOLINO)ETHYL-1-PHENYLCYCLOHEXANE-1-CARBOXYLATE; MORPHOLINE DERIVATIVE; SIGMA OPIATE RECEPTOR; SIGMA-1 RECEPTOR;

EID: 84924711991     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0106533     Document Type: Article
Times cited : (116)

References (48)
  • 1
    • 0017064976 scopus 로고
    • The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog
    • Martin WR, Eades CG, Thompson JA, Huppler RE, Gilbert PE (1976) The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog. J Pharmacol Exp Ther 197: 517-532.
    • (1976) J Pharmacol Exp Ther , vol.197 , pp. 517-532
    • Martin, W.R.1    Eades, C.G.2    Thompson, J.A.3    Huppler, R.E.4    Gilbert, P.E.5
  • 2
    • 70349116879 scopus 로고    scopus 로고
    • The pharmacology of sigma-1 receptors
    • Maurice T, Su TP (2009) The pharmacology of sigma-1 receptors. Pharmacol Ther 124: 195-206.
    • (2009) Pharmacol Ther , vol.124 , pp. 195-206
    • Maurice, T.1    Su, T.P.2
  • 3
    • 0019935002 scopus 로고
    • Evidence for sigma opioid receptor: Binding of [3H] SKF-10047 to etorphine-inaccessible sites in guinea-pig brain
    • Su TP (1982) Evidence for sigma opioid receptor: binding of [3H] SKF-10047 to etorphine-inaccessible sites in guinea-pig brain. J Pharmacol Exp Ther 223: 284-290.
    • (1982) J Pharmacol Exp Ther , vol.223 , pp. 284-290
    • Su, T.P.1
  • 4
    • 0024281403 scopus 로고
    • Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems
    • Su TP, London ED, Jaffe JH (1988) Steroid binding at sigma receptors suggests a link between endocrine, nervous, and immune systems. Science 240: 219-221.
    • (1988) Science , vol.240 , pp. 219-221
    • Su, T.P.1    London, E.D.2    Jaffe, J.H.3
  • 5
    • 0028180570 scopus 로고
    • Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: Characterization by ligand binding and photoaffinity labeling
    • Hellewell SB, Bruce A, Feinstein G, Orringer J, Williams W, et al. (1994) Rat liver and kidney contain high densities of sigma 1 and sigma 2 receptors: characterization by ligand binding and photoaffinity labeling. Eur J Pharmacol 268: 9-18.
    • (1994) Eur J Pharmacol , vol.268 , pp. 9-18
    • Hellewell, S.B.1    Bruce, A.2    Feinstein, G.3    Orringer, J.4    Williams, W.5
  • 7
    • 35549006797 scopus 로고    scopus 로고
    • Sigma-1 Receptor Chaperones at the ER- Mitochondrion Interface Regulate Ca2+ Signaling and Cell Survival
    • DOI 10.1016/j.cell.2007.08.036, PII S0092867407010999
    • Hayashi T, Su TP (2007) Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2+) signaling and cell survival. Cell 131: 596-610. (Pubitemid 350017760)
    • (2007) Cell , vol.131 , Issue.3 , pp. 596-610
    • Hayashi, T.1    Su, T.-P.2
  • 8
    • 84885817275 scopus 로고    scopus 로고
    • Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival
    • Mori T, Hayashi T, Hayashi E, Su TP (2013) Sigma-1 receptor chaperone at the ER-mitochondrion interface mediates the mitochondrion-ER-nucleus signaling for cellular survival. PLoS One 8: e76941.
    • (2013) PLoS One , vol.8
    • Mori, T.1    Hayashi, T.2    Hayashi, E.3    Su, T.P.4
  • 10
    • 0028822294 scopus 로고
    • The sigma ligand SR 31747 prevents the development of acute graft-versus-host disease in mice by blocking IFN-gamma and GM-CSF mRNA expression
    • Carayon P, Bouaboula M, Loubet JF, Bourrie B, Petitpretre G, et al. (1995) The sigma ligand SR 31747 prevents the development of acute graft-versus-host disease in mice by blocking IFN-gamma and GM-CSF mRNA expression. Int J Immunopharmacol 17: 753-761.
    • (1995) Int J Immunopharmacol , vol.17 , pp. 753-761
    • Carayon, P.1    Bouaboula, M.2    Loubet, J.F.3    Bourrie, B.4    Petitpretre, G.5
  • 11
    • 0028818066 scopus 로고
    • Enhancement of endotoxin-induced interleukin-10 production by SR 31747A, a sigma ligand
    • Bourrie B, Bouaboula M, Benoit JM, Derocq JM, Esclangon M, et al. (1995) Enhancement of endotoxin-induced interleukin-10 production by SR 31747A, a sigma ligand. Eur J Immunol 25: 2882-2887.
    • (1995) Eur J Immunol , vol.25 , pp. 2882-2887
    • Bourrie, B.1    Bouaboula, M.2    Benoit, J.M.3    Derocq, J.M.4    Esclangon, M.5
  • 12
    • 84883466296 scopus 로고    scopus 로고
    • A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity
    • Frecska E, Szabo A, Winkelman MJ, Luna LE, McKenna DJ (2013) A possibly sigma-1 receptor mediated role of dimethyltryptamine in tissue protection, regeneration, and immunity. J Neural Transm 120: 1295-1303.
    • (2013) J Neural Transm , vol.120 , pp. 1295-1303
    • Frecska, E.1    Szabo, A.2    Winkelman, M.J.3    Luna, L.E.4    McKenna, D.J.5
  • 13
    • 66149131076 scopus 로고    scopus 로고
    • When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor
    • Su TP, Hayashi T, Vaupel DB (2009) When the endogenous hallucinogenic trace amine N,N-dimethyltryptamine meets the sigma-1 receptor. Sci Signal 2: pe12.
    • (2009) Sci Signal , vol.2
    • Su, T.P.1    Hayashi, T.2    Vaupel, D.B.3
  • 14
    • 79952354609 scopus 로고    scopus 로고
    • Psychedelic 5-methoxy-N,N-dimethyltryptamine: Metabolism, pharmacokinetics, drug interactions, and pharmacological actions
    • Shen HW, Jiang XL, Winter JC, Yu AM (2010) Psychedelic 5-methoxy-N,N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions. Curr Drug Metab 11: 659-666.
    • (2010) Curr Drug Metab , vol.11 , pp. 659-666
    • Shen, H.W.1    Jiang, X.L.2    Winter, J.C.3    Yu, A.M.4
  • 15
    • 56549112734 scopus 로고    scopus 로고
    • Endogenous hallucinogens as ligands of the trace amine receptors: A possible role in sensory perception
    • Wallach JV (2009) Endogenous hallucinogens as ligands of the trace amine receptors: a possible role in sensory perception. Med Hypotheses 72: 91-94.
    • (2009) Med Hypotheses , vol.72 , pp. 91-94
    • Wallach, J.V.1
  • 16
    • 60149107790 scopus 로고    scopus 로고
    • The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator
    • Fontanilla D, Johannessen M, Hajipour AR, Cozzi NV, Jackson MB, et al. (2009) The hallucinogen N,N-dimethyltryptamine (DMT) is an endogenous sigma-1 receptor regulator. Science 323: 934-937.
    • (2009) Science , vol.323 , pp. 934-937
    • Fontanilla, D.1    Johannessen, M.2    Hajipour, A.R.3    Cozzi, N.V.4    Jackson, M.B.5
  • 17
    • 80755129122 scopus 로고    scopus 로고
    • Autonomic, neuroendocrine, and immunological effects of ayahuasca: A comparative study with d-amphetamine
    • Dos Santos RG, Valle M, Bouso JC, Nomdedeu JF, Rodriguez-Espinosa J, et al. (2011) Autonomic, neuroendocrine, and immunological effects of ayahuasca: a comparative study with d-amphetamine. J Clin Psychopharmacol 31: 717-726.
    • (2011) J Clin Psychopharmacol , vol.31 , pp. 717-726
    • Dos Santos, R.G.1    Valle, M.2    Bouso, J.C.3    Nomdedeu, J.F.4    Rodriguez-Espinosa, J.5
  • 18
    • 84899133066 scopus 로고    scopus 로고
    • Collaboration of Toll-like and RIG-I-like receptors in human dendritic cells: TRIGgering antiviral innate immune responses
    • Szabo A, Rajnavolgyi E (2013) Collaboration of Toll-like and RIG-I-like receptors in human dendritic cells: tRIGgering antiviral innate immune responses. Am J Clin Exp Immunol 2: 195-207.
    • (2013) Am J Clin Exp Immunol , vol.2 , pp. 195-207
    • Szabo, A.1    Rajnavolgyi, E.2
  • 19
    • 34848837386 scopus 로고    scopus 로고
    • Taking dendritic cells into medicine
    • DOI 10.1038/nature06175, PII NATURE06175
    • Steinman RM, Banchereau J (2007) Taking dendritic cells into medicine. Nature 449: 419-426. (Pubitemid 47509552)
    • (2007) Nature , vol.449 , Issue.7161 , pp. 419-426
    • Steinman, R.M.1    Banchereau, J.2
  • 20
    • 84856159067 scopus 로고    scopus 로고
    • Transcriptional programming of the dendritic cell network
    • Belz GT, Nutt SL (2012) Transcriptional programming of the dendritic cell network. Nat Rev Immunol 12: 101-113.
    • (2012) Nat Rev Immunol , vol.12 , pp. 101-113
    • Belz, G.T.1    Nutt, S.L.2
  • 21
    • 77958500026 scopus 로고    scopus 로고
    • Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas
    • Cheong C, Matos I, Choi JH, Dandamudi DB, Shrestha E, et al. (2010) Microbial stimulation fully differentiates monocytes to DC-SIGN/CD209(+) dendritic cells for immune T cell areas. Cell 143: 416-429.
    • (2010) Cell , vol.143 , pp. 416-429
    • Cheong, C.1    Matos, I.2    Choi, J.H.3    Dandamudi, D.B.4    Shrestha, E.5
  • 22
    • 84882596593 scopus 로고    scopus 로고
    • Stress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behavior
    • Wohleb ES, Powell ND, Godbout JP, Sheridan JF (2013) Stress-induced recruitment of bone marrow-derived monocytes to the brain promotes anxiety-like behavior. J Neurosci 33: 13820-13833.
    • (2013) J Neurosci , vol.33 , pp. 13820-13833
    • Wohleb, E.S.1    Powell, N.D.2    Godbout, J.P.3    Sheridan, J.F.4
  • 23
    • 84863468916 scopus 로고    scopus 로고
    • RLR-mediated production of interferon-beta by a human dendritic cell subset and its role in virus-specific immunity
    • Szabo A, Bene K, Gogolak P, Rethi B, Lanyi A, et al. (2012) RLR-mediated production of interferon-beta by a human dendritic cell subset and its role in virus-specific immunity. J Leukoc Biol 92: 159-169.
    • (2012) J Leukoc Biol , vol.92 , pp. 159-169
    • Szabo, A.1    Bene, K.2    Gogolak, P.3    Rethi, B.4    Lanyi, A.5
  • 24
    • 84866487963 scopus 로고    scopus 로고
    • Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3- phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke
    • Ruscher K, Inacio AR, Valind K, Rowshan Ravan A, Kuric E, et al. (2012) Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3- phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke. PLoS One 7: e45118.
    • (2012) PLoS One , vol.7
    • Ruscher, K.1    Inacio, A.R.2    Valind, K.3    Rowshan Ravan, A.4    Kuric, E.5
  • 25
    • 84886816838 scopus 로고    scopus 로고
    • Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation
    • Peviani M, Salvaneschi E, Bontempi L, Petese A, Manzo A, et al. (2014) Neuroprotective effects of the Sigma-1 receptor (S1R) agonist PRE-084, in a mouse model of motor neuron disease not linked to SOD1 mutation. Neurobiol Dis 62: 218-232.
    • (2014) Neurobiol Dis , vol.62 , pp. 218-232
    • Peviani, M.1    Salvaneschi, E.2    Bontempi, L.3    Petese, A.4    Manzo, A.5
  • 26
    • 84890873535 scopus 로고    scopus 로고
    • Human T-cell leukemia/lymphoma virus type 1 p30, but not p12/p8, counteracts toll-like receptor 3 (TLR3) and TLR4 signaling in human monocytes and dendritic cells
    • Fenizia C, Fiocchi M, Jones K, Parks RW, Ceribelli M, et al. (2014) Human T-cell leukemia/lymphoma virus type 1 p30, but not p12/p8, counteracts toll-like receptor 3 (TLR3) and TLR4 signaling in human monocytes and dendritic cells. J Virol 88: 393-402.
    • (2014) J Virol , vol.88 , pp. 393-402
    • Fenizia, C.1    Fiocchi, M.2    Jones, K.3    Parks, R.W.4    Ceribelli, M.5
  • 27
    • 0028118371 scopus 로고
    • Dose-response study of N,N-dimethyltryptamine in humans: I. Neuroendocrine, autonomic, and cardiovascular effects
    • Strassman RJ, Qualls CR (1994) Dose-response study of N,N-dimethyltryptamine in humans. I. Neuroendocrine, autonomic, and cardiovascular effects. Arch Gen Psychiatry 51: 85-97. (Pubitemid 24054310)
    • (1994) Archives of General Psychiatry , vol.51 , Issue.2 , pp. 85-97
    • Strassman, R.J.1    Qualls, C.R.2
  • 28
    • 79959479988 scopus 로고    scopus 로고
    • Nonlinear pharmacokinetics of 5-methoxy-N,N-dimethyltryptamine in mice
    • Shen HW, Jiang XL, Yu AM (2011) Nonlinear pharmacokinetics of 5-methoxy-N,N-dimethyltryptamine in mice. Drug Metab Dispos 39: 1227-1234.
    • (2011) Drug Metab Dispos , vol.39 , pp. 1227-1234
    • Shen, H.W.1    Jiang, X.L.2    Yu, A.M.3
  • 29
    • 77952313777 scopus 로고    scopus 로고
    • Differentiation of effector CD4 T cell populations (*)
    • Zhu J, Yamane H, Paul WE (2010) Differentiation of effector CD4 T cell populations (*). Annu Rev Immunol 28: 445-489.
    • (2010) Annu Rev Immunol , vol.28 , pp. 445-489
    • Zhu, J.1    Yamane, H.2    Paul, W.E.3
  • 30
    • 84862736185 scopus 로고    scopus 로고
    • Mechanisms regulating regional localization of inflammation during CNS autoimmunity
    • Pierson E, Simmons SB, Castelli L, Goverman JM (2012) Mechanisms regulating regional localization of inflammation during CNS autoimmunity. Immunol Rev 248: 205-215.
    • (2012) Immunol Rev , vol.248 , pp. 205-215
    • Pierson, E.1    Simmons, S.B.2    Castelli, L.3    Goverman, J.M.4
  • 32
    • 69549120391 scopus 로고    scopus 로고
    • Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration
    • Jang H, Boltz D, Sturm-Ramirez K, Shepherd KR, Jiao Y, et al. (2009) Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration. Proc Natl Acad Sci U S A 106: 14063-14068.
    • (2009) Proc Natl Acad Sci U S a , vol.106 , pp. 14063-14068
    • Jang, H.1    Boltz, D.2    Sturm-Ramirez, K.3    Shepherd, K.R.4    Jiao, Y.5
  • 33
    • 84863389813 scopus 로고    scopus 로고
    • Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice
    • Jurgens HA, Amancherla K, Johnson RW (2012) Influenza infection induces neuroinflammation, alters hippocampal neuron morphology, and impairs cognition in adult mice. J Neurosci 32: 3958-3968.
    • (2012) J Neurosci , vol.32 , pp. 3958-3968
    • Jurgens, H.A.1    Amancherla, K.2    Johnson, R.W.3
  • 36
    • 0345337411 scopus 로고
    • Enzymatic formation of psychotomimetic metabolites from normally occurring compounds
    • Axelrod J (1961) Enzymatic formation of psychotomimetic metabolites from normally occurring compounds. Science 134: 343.
    • (1961) Science , vol.134 , pp. 343
    • Axelrod, J.1
  • 37
    • 0017752753 scopus 로고
    • The in vitro identification of dimethyltryptamine (DMT) in mammalian brain and its characterization as a possible endogenous neuroregulatory agent
    • Christian ST, Harrison R, Quayle E, Pagel J, Monti J (1977) The in vitro identification of dimethyltryptamine (DMT) in mammalian brain and its characterization as a possible endogenous neuroregulatory agent. Biochem Med 18: 164-183. (Pubitemid 8213838)
    • (1977) Biochemical Medicine , vol.18 , Issue.2 , pp. 164-183
    • Christian, S.T.1    Harrison, R.2    Quayle, E.3
  • 38
    • 0036786188 scopus 로고    scopus 로고
    • Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: Mechanisms of action
    • Theodorou V, Chovet M, Eutamene H, Fargeau H, Dassaud M, et al. (2002) Antidiarrhoeal properties of a novel sigma ligand (JO 2871) on toxigenic diarrhoea in mice: mechanisms of action. Gut 51: 522-528.
    • (2002) Gut , vol.51 , pp. 522-528
    • Theodorou, V.1    Chovet, M.2    Eutamene, H.3    Fargeau, H.4    Dassaud, M.5
  • 39
    • 84900803034 scopus 로고    scopus 로고
    • The Brain-Immune-Gut Triangle: Innate Immunity in Psychiatric and Neurological Disorders
    • Szabo A, Rajnavolgyi E (2013) The Brain-Immune-Gut Triangle: Innate Immunity in Psychiatric and Neurological Disorders. Current Immunology Review 9: 241-248.
    • (2013) Current Immunology Review , vol.9 , pp. 241-248
    • Szabo, A.1    Rajnavolgyi, E.2
  • 40
    • 70349558522 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
    • Harold D, Abraham R, Hollingworth P, Sims R, Gerrish A, et al. (2009) Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet 41: 1088-1093.
    • (2009) Nat Genet , vol.41 , pp. 1088-1093
    • Harold, D.1    Abraham, R.2    Hollingworth, P.3    Sims, R.4    Gerrish, A.5
  • 41
    • 78549264026 scopus 로고    scopus 로고
    • Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
    • Lambert JC, Heath S, Even G, Campion D, Sleegers K, et al. (2009) Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet 41: 1094-1099.
    • (2009) Nat Genet , vol.41 , pp. 1094-1099
    • Lambert, J.C.1    Heath, S.2    Even, G.3    Campion, D.4    Sleegers, K.5
  • 42
    • 33646926705 scopus 로고    scopus 로고
    • The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology
    • DOI 10.1523/JNEUROSCI.0099-06.2006
    • Meyer U, Nyffeler M, Engler A, Urwyler A, Schedlowski M, et al. (2006) The time of prenatal immune challenge determines the specificity of inflammation-mediated brain and behavioral pathology. J Neurosci 26: 4752-4762. (Pubitemid 44315314)
    • (2006) Journal of Neuroscience , vol.26 , Issue.18 , pp. 4752-4762
    • Meyer, U.1    Nyffeler, M.2    Engler, A.3    Urwyler, A.4    Schedlowski, M.5    Knuesel, I.6    Yee, B.K.7    Feldon, J.8
  • 43
    • 36949028725 scopus 로고    scopus 로고
    • Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge
    • DOI 10.1038/sj.npp.1301413, PII 1301413
    • Meyer U, Nyffeler M, Schwendener S, Knuesel I, Yee BK, et al. (2008) Relative prenatal and postnatal maternal contributions to schizophrenia-related neurochemical dysfunction after in utero immune challenge. Neuropsychopharmacology 33: 441-456. (Pubitemid 350243354)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.2 , pp. 441-456
    • Meyer, U.1    Nyffeler, M.2    Schwendener, S.3    Knuesel, I.4    Yee, B.K.5    Feldon, J.6
  • 44
    • 33751103938 scopus 로고    scopus 로고
    • The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats
    • DOI 10.1007/s00213-006-0566-1
    • Krebs-Thomson K, Ruiz EM, Masten V, Buell M, Geyer MA (2006) The roles of 5-HT1A and 5-HT2 receptors in the effects of 5-MeO-DMT on locomotor activity and prepulse inhibition in rats. Psychopharmacology (Berl) 189: 319-329. (Pubitemid 44772815)
    • (2006) Psychopharmacology , vol.189 , Issue.3 , pp. 319-329
    • Krebs-Thomson, K.1    Ruiz, E.M.2    Masten, V.3    Buell, M.4    Geyer, M.A.5
  • 45
    • 15244339013 scopus 로고    scopus 로고
    • Endogenous psychoactive tryptamines reconsidered: An anxiolytic role for dimethyltryptamine
    • DOI 10.1016/j.mehy.2004.11.005
    • Jacob MS, Presti DE (2005) Endogenous psychoactive tryptamines reconsidered: an anxiolytic role for dimethyltryptamine. Med Hypotheses 64: 930-937. (Pubitemid 40385946)
    • (2005) Medical Hypotheses , vol.64 , Issue.5 , pp. 930-937
    • Jacob, M.S.1    Presti, D.E.2
  • 47
    • 31544457592 scopus 로고    scopus 로고
    • A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
    • DOI 10.1182/blood-2005-07-2903
    • O'Connell PJ, Wang X, Leon-Ponte M, Griffiths C, Pingle SC, et al. (2006) A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells. Blood 107: 1010-1017. (Pubitemid 43156299)
    • (2006) Blood , vol.107 , Issue.3 , pp. 1010-1017
    • O'Connell, P.J.1    Wang, X.2    Leon-Ponte, M.3    Griffiths, C.4    Pingle, S.C.5    Ahern, G.P.6
  • 48
    • 77954466075 scopus 로고    scopus 로고
    • Serum serotonin levels determine the magnitude and type of bystander effects in medium transfer experiments
    • Mothersill C, Saroya R, Smith RW, Singh H, Seymour CB (2010) Serum serotonin levels determine the magnitude and type of bystander effects in medium transfer experiments. Radiat Res 174: 119-123.
    • (2010) Radiat Res , vol.174 , pp. 119-123
    • Mothersill, C.1    Saroya, R.2    Smith, R.W.3    Singh, H.4    Seymour, C.B.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.