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Volumn 46, Issue , 2015, Pages 25-31

H2S-releasing drugs: Anti-inflammatory, cytoprotective and chemopreventative potential

Author keywords

Cytoprotection; Drug development; Gastrointestinal; Hydrogen sulfide; Inflammation

Indexed keywords

ANTIINFLAMMATORY AGENT; ANTINEOPLASTIC AGENT; CYTOPROTECTIVE AGENT; HYDROGEN SULFIDE; NONSTEROID ANTIINFLAMMATORY AGENT; PROTECTIVE AGENT;

EID: 84924709971     PISSN: 10898603     EISSN: 10898611     Source Type: Journal    
DOI: 10.1016/j.niox.2014.11.010     Document Type: Review
Times cited : (78)

References (56)
  • 1
    • 84884965963 scopus 로고    scopus 로고
    • Hydrogen sulfide-based therapeutics and gastrointestinal diseases: Translating physiology to treatments
    • M.V. Chan, and J.L. Wallace Hydrogen sulfide-based therapeutics and gastrointestinal diseases: translating physiology to treatments Am. J. Physiol. Gastrointest. Liver Physiol 305 2013 G467 G473
    • (2013) Am. J. Physiol. Gastrointest. Liver Physiol , vol.305 , pp. G467-G473
    • Chan, M.V.1    Wallace, J.L.2
  • 4
    • 84891795464 scopus 로고    scopus 로고
    • Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells
    • H.B. Ma, S. Huang, X.R. Yin, Y. Zhang, and Z.L. Di Apoptotic pathway induced by diallyl trisulfide in pancreatic cancer cells World J. Gastroenterol 20 2014 193 203
    • (2014) World J. Gastroenterol , vol.20 , pp. 193-203
    • Ma, H.B.1    Huang, S.2    Yin, X.R.3    Zhang, Y.4    Di, Z.L.5
  • 5
    • 84930223471 scopus 로고    scopus 로고
    • Utilizing hydrogen sulfide as a novel anti-cancer agent by targeting cancer glycolysis and pH imbalance
    • Z.W. Lee, X.Y. Teo, E.Y. Tay, C.H. Tan, T. Hagen, and P.K. Moore Utilizing hydrogen sulfide as a novel anti-cancer agent by targeting cancer glycolysis and pH imbalance Br. J. Pharmacol 171 2014 4322 4336
    • (2014) Br. J. Pharmacol , vol.171 , pp. 4322-4336
    • Lee, Z.W.1    Teo, X.Y.2    Tay, E.Y.3    Tan, C.H.4    Hagen, T.5    Moore, P.K.6
  • 6
    • 26844568431 scopus 로고    scopus 로고
    • Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs
    • S. Fiorucci, E. Antonelli, E. Distrutti, G. Rizzo, A. Mencarelli, and S. Orlandi Inhibition of hydrogen sulfide generation contributes to gastric injury caused by anti-inflammatory nonsteroidal drugs Gastroenterology 129 2005 1210 1224
    • (2005) Gastroenterology , vol.129 , pp. 1210-1224
    • Fiorucci, S.1    Antonelli, E.2    Distrutti, E.3    Rizzo, G.4    Mencarelli, A.5    Orlandi, S.6
  • 7
    • 84907201013 scopus 로고    scopus 로고
    • Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis
    • K.L. Flannigan, T.A. Agbor, R.W. Blackler, J.J. Kim, W.I. Khan, and E.F. Verdu Impaired hydrogen sulfide synthesis and IL-10 signaling underlie hyperhomocysteinemia-associated exacerbation of colitis Proc. Natl Acad. Sci. U.S.A. 111 2014 13559 13564
    • (2014) Proc. Natl Acad. Sci. U.S.A. , vol.111 , pp. 13559-13564
    • Flannigan, K.L.1    Agbor, T.A.2    Blackler, R.W.3    Kim, J.J.4    Khan, W.I.5    Verdu, E.F.6
  • 8
    • 30744450012 scopus 로고    scopus 로고
    • Elevated levels of homocysteine compromise blood-brain barrier integrity in mice
    • s
    • A.F. Kamath, A.K. Chauhan, J. Kisucka, V.S. Dole, J. Loscalzo, and D.E. Handy Elevated levels of homocysteine compromise blood-brain barrier integrity in mice Blood 107 2006 591 593 s
    • (2006) Blood , vol.107 , pp. 591-593
    • Kamath, A.F.1    Chauhan, A.K.2    Kisucka, J.3    Dole, V.S.4    Loscalzo, J.5    Handy, D.E.6
  • 9
    • 84884675341 scopus 로고    scopus 로고
    • Hydrogen sulfide suppresses high glucose-induced expression of intercellular adhesion molecule-1 in endothelial cells
    • Q. Guan, X. Wang, L. Gao, J. Chen, Y. Liu, and C. Yu Hydrogen sulfide suppresses high glucose-induced expression of intercellular adhesion molecule-1 in endothelial cells J. Cardiovasc. Pharmacol 62 2013 278 284
    • (2013) J. Cardiovasc. Pharmacol , vol.62 , pp. 278-284
    • Guan, Q.1    Wang, X.2    Gao, L.3    Chen, J.4    Liu, Y.5    Yu, C.6
  • 10
    • 34247209138 scopus 로고    scopus 로고
    • Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis
    • S. Fiorucci, S. Orlandi, A. Mencarelli, G. Caliendo, V. Santagada, and E. Distrutti Enhanced activity of a hydrogen sulphide-releasing derivative of mesalamine (ATB-429) in a mouse model of colitis Br. J. Pharmacol 150 2007 996 1002
    • (2007) Br. J. Pharmacol , vol.150 , pp. 996-1002
    • Fiorucci, S.1    Orlandi, S.2    Mencarelli, A.3    Caliendo, G.4    Santagada, V.5    Distrutti, E.6
  • 14
    • 84863819676 scopus 로고    scopus 로고
    • Hydrogen sulfide and resolution of acute inflammation: A comparative study utilizing a novel fluorescent probe
    • N. Dufton, J. Natividad, E.F. Verdu, and J.L. Wallace Hydrogen sulfide and resolution of acute inflammation: a comparative study utilizing a novel fluorescent probe Scientific Rep 2 2012 499
    • (2012) Scientific Rep , vol.2 , pp. 499
    • Dufton, N.1    Natividad, J.2    Verdu, E.F.3    Wallace, J.L.4
  • 15
    • 84908180956 scopus 로고    scopus 로고
    • Cytoprotective effects of hydrogen sulfide in novel rat models of non-erosive esophagitis
    • O. Zayachkivska, O. Havryluk, N. Hrycevych, N. Bula, O. Grushka, and J.L. Wallace Cytoprotective effects of hydrogen sulfide in novel rat models of non-erosive esophagitis PLoS ONE 9 2014 e110688
    • (2014) PLoS ONE , vol.9 , pp. e110688
    • Zayachkivska, O.1    Havryluk, O.2    Hrycevych, N.3    Bula, N.4    Grushka, O.5    Wallace, J.L.6
  • 16
    • 84862909327 scopus 로고    scopus 로고
    • Hydrogen sulfide-linked sulfhydration of NFkB mediates its antiapoptotic actions
    • N. Sen, B.D. Paul, M.M. Gadalla, A.K. Mustafa, T. Sen, and R. Xu Hydrogen sulfide-linked sulfhydration of NFkB mediates its antiapoptotic actions Mol. Cell 45 2012 13 24
    • (2012) Mol. Cell , vol.45 , pp. 13-24
    • Sen, N.1    Paul, B.D.2    Gadalla, M.M.3    Mustafa, A.K.4    Sen, T.5    Xu, R.6
  • 17
    • 0030018186 scopus 로고    scopus 로고
    • T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice
    • N.J. Davidson, M.W. Leach, M.M. Fort, L. Thompson-Snipes, R. Kühn, and W. Müller T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice J. Exp. Med 184 1996 241 251
    • (1996) J. Exp. Med , vol.184 , pp. 241-251
    • Davidson, N.J.1    Leach, M.W.2    Fort, M.M.3    Thompson-Snipes, L.4    Kühn, R.5    Müller, W.6
  • 18
    • 77950792008 scopus 로고    scopus 로고
    • Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract
    • J.L. Wallace Physiological and pathophysiological roles of hydrogen sulfide in the gastrointestinal tract Antiox. Redox Signal 12 2010 1125 1133
    • (2010) Antiox. Redox Signal , vol.12 , pp. 1125-1133
    • Wallace, J.L.1
  • 20
    • 36849017354 scopus 로고    scopus 로고
    • Hydrogen sulfide enhances ulcer healing in rats
    • J.L. Wallace, M. Dicay, W. McKnight, and G.R. Martin Hydrogen sulfide enhances ulcer healing in rats FASEB J. 21 2007 4070 4076
    • (2007) FASEB J. , vol.21 , pp. 4070-4076
    • Wallace, J.L.1    Dicay, M.2    McKnight, W.3    Martin, G.R.4
  • 21
    • 67651001726 scopus 로고    scopus 로고
    • Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats
    • J.L. Wallace, L. Vong, W. McKnight, M. Dicay, and G.R. Martin Endogenous and exogenous hydrogen sulfide promotes resolution of colitis in rats Gastroenterology 137 2009 569 578
    • (2009) Gastroenterology , vol.137 , pp. 569-578
    • Wallace, J.L.1    Vong, L.2    McKnight, W.3    Dicay, M.4    Martin, G.R.5
  • 24
  • 25
    • 33846184714 scopus 로고    scopus 로고
    • Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulphide-releasing diclofenac derivative in the rat
    • J.L. Wallace, G. Caliendo, V. Santagada, G. Cirino, and S. Fiorucci Gastrointestinal safety and anti-inflammatory effects of a hydrogen sulphide-releasing diclofenac derivative in the rat Gastroenterology 132 2007 261 271
    • (2007) Gastroenterology , vol.132 , pp. 261-271
    • Wallace, J.L.1    Caliendo, G.2    Santagada, V.3    Cirino, G.4    Fiorucci, S.5
  • 26
    • 77949379109 scopus 로고    scopus 로고
    • Markedly reduced toxicity of a hydrogen sulfide-releasing derivative of naproxen (ATB-346)
    • J.L. Wallace, G. Caliendo, V. Santagada, and G. Cirino Markedly reduced toxicity of a hydrogen sulfide-releasing derivative of naproxen (ATB-346) Br. J. Pharmacol 159 2010 1236 1246
    • (2010) Br. J. Pharmacol , vol.159 , pp. 1236-1246
    • Wallace, J.L.1    Caliendo, G.2    Santagada, V.3    Cirino, G.4
  • 27
    • 55949135789 scopus 로고    scopus 로고
    • Prostaglandins, NSAIDs, and gastric mucosal protection: Why doesn't the stomach digest itself?
    • J.L. Wallace Prostaglandins, NSAIDs, and gastric mucosal protection: why doesn't the stomach digest itself? Physiol. Rev 88 2008 1547 1565
    • (2008) Physiol. Rev , vol.88 , pp. 1547-1565
    • Wallace, J.L.1
  • 29
    • 84897855654 scopus 로고    scopus 로고
    • Antisecretory effect of hydrogen sulfide on gastric acid secretion and the involvement of nitric oxide
    • S.A. Mard, H. Askari, N. Neisi, and A. Veisi Antisecretory effect of hydrogen sulfide on gastric acid secretion and the involvement of nitric oxide BioMed Res. Int 2014 2014 480921 10.1155/2014/480921
    • (2014) BioMed Res. Int , vol.2014 , pp. 480921
    • Mard, S.A.1    Askari, H.2    Neisi, N.3    Veisi, A.4
  • 30
    • 0025078185 scopus 로고
    • Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process
    • J.L. Wallace, C.M. Keenan, and D.N. Granger Gastric ulceration induced by nonsteroidal anti-inflammatory drugs is a neutrophil-dependent process Am. J. Physiol 259 1990 G462 G467
    • (1990) Am. J. Physiol , vol.259 , pp. G462-G467
    • Wallace, J.L.1    Keenan, C.M.2    Granger, D.N.3
  • 31
    • 82955184551 scopus 로고    scopus 로고
    • NSAID gastropathy and enteropathy: Distinct pathogenesis likely necessitates distinct prevention strategies
    • J.L. Wallace NSAID gastropathy and enteropathy: distinct pathogenesis likely necessitates distinct prevention strategies Br. J. Pharmacol 165 2012 67 74
    • (2012) Br. J. Pharmacol , vol.165 , pp. 67-74
    • Wallace, J.L.1
  • 32
    • 84875621014 scopus 로고    scopus 로고
    • Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy
    • J.L. Wallace Mechanisms, prevention and clinical implications of nonsteroidal anti-inflammatory drug-enteropathy World J. Gastroenterol 19 2013 1861 1876
    • (2013) World J. Gastroenterol , vol.19 , pp. 1861-1876
    • Wallace, J.L.1
  • 33
    • 80053596796 scopus 로고    scopus 로고
    • Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis
    • J.L. Wallace, S. Syer, E. Denou, G. de Palma, L. Vong, and W. McKnight Proton pump inhibitors exacerbate NSAID-induced small intestinal injury by inducing dysbiosis Gastroenterology 141 2011 1314 1322
    • (2011) Gastroenterology , vol.141 , pp. 1314-1322
    • Wallace, J.L.1    Syer, S.2    Denou, E.3    De Palma, G.4    Vong, L.5    McKnight, W.6
  • 34
    • 84859509888 scopus 로고    scopus 로고
    • Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence
    • R. Blackler, S. Syer, M. Bolla, E. Ongini, and J.L. Wallace Gastrointestinal-sparing effects of novel NSAIDs in rats with compromised mucosal defence PLoS ONE 7 2012 e35196
    • (2012) PLoS ONE , vol.7 , pp. e35196
    • Blackler, R.1    Syer, S.2    Bolla, M.3    Ongini, E.4    Wallace, J.L.5
  • 36
    • 33744976771 scopus 로고    scopus 로고
    • Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials
    • P.M. Kearney, C. Baigent, J. Godwin, H. Halls, J.R. Emberson, and C. Patrono Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised trials BMJ 332 2006 1302 1308
    • (2006) BMJ , vol.332 , pp. 1302-1308
    • Kearney, P.M.1    Baigent, C.2    Godwin, J.3    Halls, H.4    Emberson, J.R.5    Patrono, C.6
  • 37
    • 0029127773 scopus 로고
    • Indomethacin-induced gastric injury and leukocyte adherence in arthritic versus healthy rats
    • D.M. McCafferty, D.N. Granger, and J.L. Wallace Indomethacin-induced gastric injury and leukocyte adherence in arthritic versus healthy rats Gastroenterology 109 1995 1173 1180
    • (1995) Gastroenterology , vol.109 , pp. 1173-1180
    • McCafferty, D.M.1    Granger, D.N.2    Wallace, J.L.3
  • 40
    • 84889578648 scopus 로고    scopus 로고
    • Polypharmacy of osteoarthritis: The perfect intestinal storm
    • J.L. Wallace Polypharmacy of osteoarthritis: the perfect intestinal storm Dig. Dis. Sci 58 2013 3088 3093
    • (2013) Dig. Dis. Sci , vol.58 , pp. 3088-3093
    • Wallace, J.L.1
  • 41
    • 84924668946 scopus 로고    scopus 로고
    • Hydrogen sulfide derivatives of nonsteroidal anti-inflammatory drugs
    • J.L. Wallace, G. Cirino, V. Santagada, G. Caliendo, Hydrogen sulfide derivatives of nonsteroidal anti-inflammatory drugs, United States Patent Application No. WO/2008/009127 (2008).
    • (2008)
    • Wallace, J.L.1    Cirino, G.2    Santagada, V.3    Caliendo, G.4
  • 42
    • 84859987078 scopus 로고    scopus 로고
    • Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice
    • A. LoGuidice, B.D. Wallace, L. Bendel, M.R. Redinbo, and U.A. Boelsterli Pharmacologic targeting of bacterial β-glucuronidase alleviates nonsteroidal anti-inflammatory drug-induced enteropathy in mice J. Pharmacol. Exp. Ther 341 2012 447 454
    • (2012) J. Pharmacol. Exp. Ther , vol.341 , pp. 447-454
    • Loguidice, A.1    Wallace, B.D.2    Bendel, L.3    Redinbo, M.R.4    Boelsterli, U.A.5
  • 43
    • 40749097319 scopus 로고    scopus 로고
    • Aspirin: Promise and resistance in the new millennium
    • C. Patrono, and B. Rocca Aspirin: promise and resistance in the new millennium Arteriosclerosis Thromb. Vasc. Biol 28 2008 S25 S32
    • (2008) Arteriosclerosis Thromb. Vasc. Biol , vol.28 , pp. S25-S32
    • Patrono, C.1    Rocca, B.2
  • 44
    • 0037421984 scopus 로고    scopus 로고
    • A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer
    • R.S. Sandler, S. Halabi, J.A. Baron, S. Budinger, E. Paskett, and R. Keresztes A randomized trial of aspirin to prevent colorectal adenomas in patients with previous colorectal cancer N. Engl. J. Med 348 2003 883 890
    • (2003) N. Engl. J. Med , vol.348 , pp. 883-890
    • Sandler, R.S.1    Halabi, S.2    Baron, J.A.3    Budinger, S.4    Paskett, E.5    Keresztes, R.6
  • 45
    • 0027237664 scopus 로고
    • Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: Case-control study of subjects participating in the Nottingham faecal occult blood screening programme
    • R.F. Logan, J. Little, P.G. Hawtin, and J.D. Hardcastle Effect of aspirin and non-steroidal anti-inflammatory drugs on colorectal adenomas: case-control study of subjects participating in the Nottingham faecal occult blood screening programme BMJ 307 1993 285 289
    • (1993) BMJ , vol.307 , pp. 285-289
    • Logan, R.F.1    Little, J.2    Hawtin, P.G.3    Hardcastle, J.D.4
  • 46
    • 84903513284 scopus 로고    scopus 로고
    • Aspirin and other NSAIDs as chemoprevention agents in melanoma
    • J.R. Goodman, and D. Grossman Aspirin and other NSAIDs as chemoprevention agents in melanoma Cancer Prev. Res 7 2014 557 564
    • (2014) Cancer Prev. Res , vol.7 , pp. 557-564
    • Goodman, J.R.1    Grossman, D.2
  • 47
    • 84906938826 scopus 로고    scopus 로고
    • Targeting epigenetic mechanisms and microRNAs by aspirin and other nonsteroidal anti-inflammatory agents - Implications for cancer treatment and chemoprevention
    • E. Yiannakopoulou Targeting epigenetic mechanisms and microRNAs by aspirin and other nonsteroidal anti-inflammatory agents - implications for cancer treatment and chemoprevention Cell. Oncol 37 2014 167 178
    • (2014) Cell. Oncol , vol.37 , pp. 167-178
    • Yiannakopoulou, E.1
  • 48
    • 0031749806 scopus 로고    scopus 로고
    • Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: Implications for gastrointestinal toxicity
    • J.L. Wallace, A. Bak, G.W. McKnight, S. Asfaha, K.A. Sharkey, and W.K. MacNaughton Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity Gastroenterology 115 1998 101 109
    • (1998) Gastroenterology , vol.115 , pp. 101-109
    • Wallace, J.L.1    Bak, A.2    McKnight, G.W.3    Asfaha, S.4    Sharkey, K.A.5    Macnaughton, W.K.6
  • 49
    • 84893465586 scopus 로고    scopus 로고
    • Anti-cancer activity of new designer hydrogen sulfide-donating hybrids
    • K. Kashfi Anti-cancer activity of new designer hydrogen sulfide-donating hybrids Antioxid. Redox Signal 20 2014 831 846
    • (2014) Antioxid. Redox Signal , vol.20 , pp. 831-846
    • Kashfi, K.1
  • 50
    • 84907599036 scopus 로고    scopus 로고
    • Enhanced chemopreventative effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer
    • W. Elsheikh, R.W. Blackler, K.L. Flannigan, and J.L. Wallace Enhanced chemopreventative effects of a hydrogen sulfide-releasing anti-inflammatory drug (ATB-346) in experimental colorectal cancer Nitric Oxide 41 2014 131 137
    • (2014) Nitric Oxide , vol.41 , pp. 131-137
    • Elsheikh, W.1    Blackler, R.W.2    Flannigan, K.L.3    Wallace, J.L.4
  • 51
    • 0015908975 scopus 로고
    • Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane
    • J.M. Ward, R.S. Yamamoto, and C.A. Brown Pathology of intestinal neoplasms and other lesions in rats exposed to azoxymethane J. Nat. Cancer Inst 51 1973 1029 1039
    • (1973) J. Nat. Cancer Inst , vol.51 , pp. 1029-1039
    • Ward, J.M.1    Yamamoto, R.S.2    Brown, C.A.3
  • 52
    • 0023815324 scopus 로고
    • Specificity study to evaluate induction of aberrant crypts in murine colons
    • E.A. McLellan, and R.P. Bird Specificity study to evaluate induction of aberrant crypts in murine colons Cancer Res 48 1988 6183 6186
    • (1988) Cancer Res , vol.48 , pp. 6183-6186
    • McLellan, E.A.1    Bird, R.P.2
  • 54
    • 33750736082 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia
    • S.J. Baek, R. Okazaki, S.H. Lee, J. Martinez, J.S. Kim, and K. Yamaguchi Nonsteroidal anti-inflammatory drug-activated gene-1 over expression in transgenic mice suppresses intestinal neoplasia Gastroenterology 131 2006 1553 1560
    • (2006) Gastroenterology , vol.131 , pp. 1553-1560
    • Baek, S.J.1    Okazaki, R.2    Lee, S.H.3    Martinez, J.4    Kim, J.S.5    Yamaguchi, K.6
  • 55
    • 84876135908 scopus 로고    scopus 로고
    • Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2
    • G. Yang, K. Zhao, Y. Ju, S. Mani, Q. Cao, and S. Puukila Hydrogen sulfide protects against cellular senescence via S-sulfhydration of Keap1 and activation of Nrf2 Antiox. Redox Signal 18 2013 1906 1919
    • (2013) Antiox. Redox Signal , vol.18 , pp. 1906-1919
    • Yang, G.1    Zhao, K.2    Ju, Y.3    Mani, S.4    Cao, Q.5    Puukila, S.6
  • 56
    • 84891795464 scopus 로고    scopus 로고
    • Apoptotic pathway induced by diallyl trisulfide in pancreatic cells
    • H.B. Ma, S. Huang, X.R. Yin, Y. Zhang, and Z.L. Di Apoptotic pathway induced by diallyl trisulfide in pancreatic cells World J. Gastroenterol 20 2014 193 203
    • (2014) World J. Gastroenterol , vol.20 , pp. 193-203
    • Ma, H.B.1    Huang, S.2    Yin, X.R.3    Zhang, Y.4    Di, Z.L.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.