Natural course of metabolically healthy abdominal obese adults after 10 years of follow-up: The Tehran Lipid and Glucose Study

International Journal of Obesity

Volumn 39, Issue 3, 2015, Pages 514-519

  Eshtiaghi, R ^a   Keihani, S ^b   Hosseinpanah, F ^b   Barzin, M ^b   Azizi, F ^c  

^a AJA UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; GLUCOSE BLOOD LEVEL; HIGH DENSITY LIPOPROTEIN; LIPID; TRIACYLGLYCEROL;

ABDOMINAL OBESITY; ADULT; ANTHROPOMETRIC PARAMETERS; ARTICLE; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; COMPARATIVE STUDY; FEMALE; FOLLOW UP; HUMAN; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC PARAMETERS; METABOLIC SYNDROME X; METABOLICALLY HEALTHY ABDOMINAL OBESE; PHENOTYPE; PRIORITY JOURNAL; PROSPECTIVE STUDY; BLOOD; BODY MASS; GLUCOSE BLOOD LEVEL; IRAN; METABOLISM; OBESITY, ABDOMINAL; PATHOPHYSIOLOGY; PREVALENCE;

ADULT; BLOOD GLUCOSE; BODY MASS INDEX; CHOLESTEROL, HDL; FEMALE; FOLLOW-UP STUDIES; HUMANS; HYPERTRIGLYCERIDEMIA; INSULIN RESISTANCE; IRAN; LIPIDS; LIPOPROTEINS, HDL; MALE; OBESITY, ABDOMINAL; PHENOTYPE; PREVALENCE; PROSPECTIVE STUDIES; TRIGLYCERIDES;

EID: 84924700304     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2014.176     Document Type: Article

References (44)

1. World Health Organization. Global health risks: mortality and burden of disease attributable to selected major risks. World Health Organization: Geneva, 2009
2. Guh DP, Zhang W, Bansback N, Amarsi Z, Birmingham CL, Anis AH. The incidence of co-morbidities related to obesity and overweight: a systematic review and meta-Analysis. BMC Public Health 2009; 9: 88
3. Ruderman NB, Schneider SH, Berchtold P. The "metabolically-obese, " normalweight individual. Am J Clin Nutr 1981; 34: 1617-1621
4. Sims EA. Are there persons who are obese, but metabolically healthy? Metabolism 2001; 50: 1499-1504
5. Karelis AD, Brochu M, Rabasa-Lhoret R. Can we identify metabolically healthy but obese individuals (MHO)? Diabetes Metab 2004; 30: 569-572
6. Meigs JB, Wilson PW, Fox CS, Vasan RS, Nathan DM, Sullivan LM, et al. Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab 2006; 91: 2906-2912
7. Hamer M, Stamatakis E. Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality. J Clin Endocrinol Metab 2012; 97: 2482-2488
8. Kramer CK, Zinman B, Retnakaran R. Are metabolically healthy overweight and obesity benign conditions?: a systematic review and meta-Analysis. Ann Intern Med 2013; 159: 758-769
9. Aung K, Lorenzo C, Hinojosa MA, Haffner SM. Risk of developing diabetes and cardiovascular disease in metabolically unhealthy normal-weight and metabolically healthy obese individuals. J Clin Endocrinol Metab 2013; 99: 462-468
10. Bluher M. Are there still healthy obese patients? Curr Opin Endocrinol Diabetes Obes 2012; 19: 341-346
11. Despres JP. Health consequences of visceral obesity. Ann Med 2001; 33: 534-541
12. Brenner DR, Tepylo K, Eny KM, Cahill LE, El-Sohemy A. Comparison of body mass index and waist circumference as predictors of cardiometabolic health in a population of young Canadian adults. Diabetol Metab Syndr 2010; 2: 28
13. Janiszewski PM, Janssen I, Ross R. Does waist circumference predict diabetes and cardiovascular disease beyond commonly evaluated cardiometabolic risk factors? Diabetes Care 2007; 30: 3105-3109
14. van der AD, Nooyens AC, van Duijnhoven FJ, Verschuren WM, Boer JM. All-cause mortality risk of metabolically healthy abdominal obese individuals: The EPIC-MORGEN study. Obesity (Silver Spring) 2013; 22: 557-564
15. Appleton SL, Seaborn CJ, Visvanathan R, Hill CL, Gill TK, Taylor AW, et al. Diabetes and cardiovascular disease outcomes in the metabolically healthy obese phenotype: a cohort study. Diabetes Care 2013; 36: 2388-2394
16. Soriguer F, Gutierrez-Repiso C, Rubio-Martin E, Garcia-Fuentes E, Almaraz MC, Colomo N, et al. Metabolically healthy but obese, a matter of time? Findings from the prospective Pizarra study. J Clin Endocrinol Metab 2013; 98: 2318-2325
17. Hosseinpanah F, Nazeri P, Ghareh S, Tohidi M, Azizi F. Predictors of the incident metabolic syndrome in healthy obese subjects: a decade of follow-up from the Tehran Lipid and Glucose Study. Eur J Clin Nutr 2013; 68: 295-299
18. Cheung BM, Wat NM, Tam S, Thomas GN, Leung GM, Cheng CH, et al. Components of the metabolic syndrome predictive of its development: a 6-year longitudinal study in Hong Kong Chinese. Clin Endocrinol 2008; 68: 730-737
19. Heidari Z, Hosseinpanah F, Mehrabi Y, Safarkhani M, Azizi F. Predictive power of the components of metabolic syndrome in its development: a 6.5-year follow-up in the Tehran Lipid and Glucose Study (TLGS). Eur J Clin Nutr 2010; 64: 1207-1214
20. Azizi F, Rahmani M, Emami H, Madjid M. Tehran lipid and glucose study: rationale and design. CVD Prevention 2000; 3: 242-247
21. Ainsworth BE, Jacobs Jr. DR, Leon AS. Validity and reliability of self-reported physical activity status: the Lipid Research Clinics questionnaire. Med Sci Sports Exerc 1993; 25: 92-98
22. Azizi F, Ghanbarian A, Momenan AA, Hadaegh F, Mirmiran P, Hedayati M, et al. Prevention of non-communicable disease in a population in nutrition transition: Tehran Lipid and Glucose Study phase II. Trials 2009; 10: 5
23. Alberti KG, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, et al. Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 2009; 120: 1640-1645
24. Delavari A, Forouzanfar MH, Alikhani S, Sharifian A, Kelishadi R. First nationwide study of the prevalence of the metabolic syndrome and optimal cutoff points of waist circumference in the Middle East: the national survey of risk factors for noncommunicable diseases of Iran. Diabetes Care 2009; 32: 1092-1097
25. Hosseinpanah F, Borzooei S, Barzin M, Farshadi M, Sarvghadi F, Azizi F. Diagnostic values of metabolic syndrome definitions for detection of insulin resistance: Tehran Lipid and Glucose Study (TLGS). Arch Iran Med 2012; 15: 606-610
26. Carmienke S, Freitag MH, Pischon T, Schlattmann P, Fankhaenel T, Goebel H, et al. General and abdominal obesity parameters and their combination in relation to mortality: a systematic review and meta-regression analysis. Eur J Clin Nutr 2013; 67: 573-585
27. Whitlock G, Lewington S, Sherliker P, Clarke R, Emberson J, Halsey J, et al. Bodymass index and cause-specific mortality in 900 000 adults: collaborative analyses of 57 prospective studies. Lancet 2009; 373: 1083-1096
28. Wormser D, Kaptoge S, Di Angelantonio E, Wood AM, Pennells L, Thompson A, et al. Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies. Lancet 2011; 377: 1085-1095
29. Matsuzawa Y, Funahashi T, Nakamura T. The concept of metabolic syndrome: contribution of visceral fat accumulation and its molecular mechanism. J Atheroscler Thromb 2011; 18: 629-639
30. de Koning L, Merchant AT, Pogue J, Anand SS. Waist circumference and waist-Tohip ratio as predictors of cardiovascular events: meta-regression analysis of prospective studies. Eur Heart J 2007; 28: 850-856
31. Janssen I, Katzmarzyk PT, Ross R. Waist circumference and not body mass index explains obesity-related health risk. Am J Clin Nutr 2004; 79: 379-384
32. van Dijk SB, Takken T, Prinsen EC, Wittink H. Different anthropometric adiposity measures and their association with cardiovascular disease risk factors: a meta-Analysis. Neth Heart J 2012; 20: 208-218
33. Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, Rittig K, et al. Identification and characterization of metabolically benign obesity in humans. Arch Int Med 2008; 168: 1609-1616
34. Voulgari C, Tentolouris N, Dilaveris P, Tousoulis D, Katsilambros N, Stefanadis C. Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals. J Am Coll Cardiol 2011; 58: 1343-1350
35. Ortega FB, Lee DC, Katzmarzyk PT, Ruiz JR, Sui X, Church TS, et al. The intriguing metabolically healthy but obese phenotype: cardiovascular prognosis and role of fitness. Eur Heart J 2013; 34: 389-397
36. Arnlov J, Ingelsson E, Sundstrom J, Lind L. Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middleaged men. Circulation 2010; 121: 230-236
37. den Engelsen C, Gorter KJ, Salome PL, Rutten GE. Development of metabolic syndrome components in adults with a healthy obese phenotype: a 3-year follow-up. Obesity (Silver Spring) 2013; 21: 1025-1030
38. Achilike I, Hazuda HP, Fowler SP, Aung K, Lorenzo C. Predicting the development of the metabolically healthy obese phenotype. Int J Obes (Lond) 2014
39. Karelis AD, Faraj M, Bastard JP, St-Pierre DH, Brochu M, PruD'homme D, et al. The metabolically healthy but obese individual presents a favorable inflammation profile. J Clin Endocrinol Metab 2005; 90: 4145-4150
40. Phillips CM, Perry IJ. Does inflammation determine metabolic health status in obese and nonobese adults? J Clin Endocrinol Metab 2013; 98: E1610-E1619
41. Wildman RP, Kaplan R, Manson JE, Rajkovic A, Connelly SA, Mackey RH, et al. Body size phenotypes and inflammation in the Women"s Health Initiative Observational Study. Obesity (Silver Spring) 2011; 19: 1482-1491
42. Hwang LC, Bai CH, You SL, Sun CA, Chen CJ. Description and prediction of the development of metabolic syndrome: a longitudinal analysis using a markov model approach. PLoS One 2013; 8: e67436
43. Pataky Z, Makoundou V, Nilsson P, Gabriel RS, Lalic K, Muscelli E, et al. Metabolic normality in overweight and obese subjects. Which parameters? Which risks? Int J Obes (Lond) 2011; 35: 1208-1215
44. Eckel RH, Alberti KG, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2010; 375: 181-183