메뉴 건너뛰기




Volumn 98, Issue 10, 2013, Pages

Does inflammation determine metabolic health status in obese and nonobese adults?

Author keywords

[No Author keywords available]

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; COMPLEMENT COMPONENT C3; CYTOKINE; DNA FORMAMIDOPYRIMIDINE GLYCOSYLASE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLASMINOGEN ACTIVATOR INHIBITOR 1; RESISTIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA;

EID: 84885206610     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2013-2038     Document Type: Article
Times cited : (231)

References (46)
  • 1
    • 0037223174 scopus 로고    scopus 로고
    • Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001
    • Mokdad AH, Ford ES, Bowman B.A., et al Prevalence of obesity, diabetes, and obesity-related health risk factors, 2001. JAMA. 2003; 289: 76-79.
    • (2003) JAMA , vol.289 , pp. 76-79
    • Mokdad, A.H.1    Ford, E.S.2    Bowman, B.A.3
  • 2
    • 33845914986 scopus 로고    scopus 로고
    • Mechanisms linking obesity with cardiovascular disease
    • Van GaalLF, Mertens IL, De Block CE. Mechanisms linking obesity with cardiovascular disease. Nature. 2006; 444: 875-880.
    • (2006) Nature , vol.444 , pp. 875-880
    • Van Gaal, L.F.1    Mertens, I.L.2    De Block, C.E.3
  • 3
    • 0019603446 scopus 로고
    • The "metabolically-obese," normal-weight individual
    • Ruderman NB, Schneider SH, Berchtold P. The "metabolically-obese, " normal-weight individual. Am J Clin Nutr. 1981; 34: 1617-1621.
    • (1981) Am J Clin Nutr , vol.34 , pp. 1617-1621
    • Ruderman, N.B.1    Schneider, S.H.2    Berchtold, P.3
  • 4
    • 49449106657 scopus 로고    scopus 로고
    • The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: Prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004)
    • Wildman RP, Muntner P, Reynolds K., et al The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004). Arch Intern Med. 2008; 168: 1617-1624.
    • (2008) Arch Intern Med. , vol.168 , pp. 1617-1624
    • Wildman, R.P.1    Muntner, P.2    Reynolds, K.3
  • 5
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • Hotamisligil GS. Inflammation and metabolic disorders. Nature. 2006; 444: 860-867.
    • (2006) Nature , vol.444 , pp. 860-867
    • Hotamisligil, G.S.1
  • 6
    • 53249149870 scopus 로고    scopus 로고
    • High adiponectin concentrations are associated with the metabolically healthy obese phenotype
    • Aguilar-Salinas C.A., Garcia EG, Robles L, et al High adiponectin concentrations are associated with the metabolically healthy obese phenotype. J Clin Endocrinol Metab. 2008; 93: 4075-4079.
    • (2008) J Clin Endocrinol Metab. , vol.93 , pp. 4075-4079
    • Aguilar-Salinas, C.A.1    Garcia, E.G.2    Robles, L.3
  • 7
    • 84883636935 scopus 로고    scopus 로고
    • Paradoxical hyperadiponectinemia is associated with the metabolically healthy obese (MHO) phenotype in african Americans
    • Doumatey AP, Bentley AR, Zhou J, Huang H., Adeyemo A, Rotimi CN Paradoxical hyperadiponectinemia is associated with the metabolically healthy obese (MHO) phenotype in African Americans. J Endocrinol Metab. 2012; 2: 51-65.
    • (2012) J Endocrinol Metab. , vol.2 , pp. 51-65
    • Doumatey, A.P.1    Bentley, A.R.2    Zhou, J.3    Huang, H.4    Adeyemo, A.5    Rotimi, C.N.6
  • 8
    • 23044454515 scopus 로고    scopus 로고
    • The metabolically healthy but obese individual presents a favorable inflammation profile
    • Karelis AD, Faraj M, Bastard J.P., et al. The metabolically healthy but obese individual presents a favorable inflammation profile. J Clin Endocrinol Metab. 2005; 90: 4145-4150.
    • (2005) J Clin Endocrinol Metab. , vol.90 , pp. 4145-4150
    • Karelis, A.D.1    Faraj, M.2    Bastard, J.P.3
  • 9
    • 78649955475 scopus 로고    scopus 로고
    • Body fat distribution and inflammation among obese older adults with and without metabolic syndrome
    • Koster A, Stenholm S, Alley D.E., et al Body fat distribution and inflammation among obese older adults with and without metabolic syndrome. Obesity (Silver Spring). 2010; 18: 2354-2361.
    • (2010) Obesity (Silver Spring) , vol.18 , pp. 2354-2361
    • Koster, A.1    Stenholm, S.2    Alley, D.E.3
  • 10
    • 33749126980 scopus 로고    scopus 로고
    • Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: Low inflammation and LDL oxidation in MHO women
    • Shin MJ, Hyun YJ, Kim O.Y., Kim JY, Jang Y, Lee JH Weight loss effect on inflammation and LDL oxidation in metabolically healthy but obese (MHO) individuals: low inflammation and LDL oxidation in MHO women. Int J Obes (Lond). 2006; 30: 1529-1534.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 1529-1534
    • Shin, M.J.1    Hyun, Y.J.2    Kim, O.Y.3    Kim, J.Y.4    Jang, Y.5    Lee, J.H.6
  • 11
    • 79959637527 scopus 로고    scopus 로고
    • Body size phenotypes and inflammation in the women's health initiative observational study
    • Wildman RP, Kaplan R, Manson J.E., et al. Body size phenotypes and inflammation in the Women's Health Initiative Observational Study. Obesity (Silver Spring). 2011; 19: 1482-1491.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 1482-1491
    • Wildman, R.P.1    Kaplan, R.2    Manson, J.E.3
  • 12
    • 78650128005 scopus 로고    scopus 로고
    • Open questions about metabolically normal obesity
    • Pataky Z, Bobbioni-Harsch E, Golay A. Open questions about metabolically normal obesity. Int J Obes (Lond). 2010; 34(SUPPL. 2): S18-S23.
    • (2010) Int J Obes (Lond) , vol.34 , Issue.SUPPL. 2
    • Pataky, Z.1    Bobbioni-Harsch, E.2    Golay, A.3
  • 14
  • 15
    • 84880791429 scopus 로고    scopus 로고
    • It is time to define metabolically obese but normal-weight (MONW) individuals
    • Lopez-Miranda J., Perez-Martinez P. It is time to define metabolically obese but normal-weight (MONW) individuals. Clin Endocrinol (Oxf). 2013; 79: 314-315.
    • (2013) Clin Endocrinol (Oxf) , vol.79 , pp. 314-315
    • Lopez-Miranda, J.1    Perez-Martinez, P.2
  • 16
    • 33747739430 scopus 로고    scopus 로고
    • Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease
    • Meigs JB, Wilson PW, Fox C.S., et al Body mass index, metabolic syndrome, and risk of type 2 diabetes or cardiovascular disease. J Clin Endocrinol Metab. 2006; 91: 2906-2912.
    • (2006) J Clin Endocrinol Metab. , vol.91 , pp. 2906-2912
    • Meigs, J.B.1    Wilson, P.W.2    Fox, C.S.3
  • 17
    • 84859447792 scopus 로고    scopus 로고
    • The association between inflammatory biomarkers and metabolically healthy obesity depends of the definition used
    • Marques-Vidal P, Velho S, Waterworth D, Waeber G, von Kanel R, Vollenweider P. The association between inflammatory biomarkers and metabolically healthy obesity depends of the definition used. Eur J Clin Nutr. 2012; 66: 426-435.
    • (2012) Eur J Clin Nutr , vol.66 , pp. 426-435
    • Marques-Vidal, P.1    Velho, S.2    Waterworth, D.3    Waeber, G.4    Von Kanel, R.5    Vollenweider, P.6
  • 18
    • 84886384928 scopus 로고    scopus 로고
    • Cohort profile: The cork and kerry diabetes and heart disease study
    • [published online ahead of print September 24, 2012] doi:10.1093/ije/ dys131
    • Kearney PM, Harrington JM, McCarthy V.J., Fitzgerald AP, Perry IJ Cohort profile: the Cork and Kerry Diabetes and Heart Disease Study [published online ahead of print September 24, 2012]. Int J Epidemiol. doi:10.1093/ije/dys131.
    • Int J Epidemiol
    • Kearney, P.M.1    Harrington, J.M.2    McCarthy, V.J.3    Fitzgerald, A.P.4    Perry, I.J.5
  • 19
    • 0042855872 scopus 로고    scopus 로고
    • International physical activity questionnaire: 12-country reliability and validity
    • Craig CL, Marshall AL, Sjostrom M, et al International physical activity questionnaire: 12-country reliability and validity. Med Sci Sports Exerc. 2003; 35: 1381-1395.
    • (2003) Med Sci Sports Exerc , vol.35 , pp. 1381-1395
    • Craig, C.L.1    Marshall, A.L.2    Sjostrom, M.3
  • 20
    • 10944263502 scopus 로고    scopus 로고
    • Dietary patterns in middleaged irish men and women defined by cluster analysis
    • Villegas R, Salim A, Collins M.M., Flynn A., Perry IJ. Dietary patterns in middle-aged Irish men and women defined by cluster analysis. Public Health Nutr. 2004; 7: 1017-1024.
    • (2004) Public Health Nutr , vol.7 , pp. 1017-1024
    • Villegas, R.1    Salim, A.2    Collins, M.M.3    Flynn, A.4    Perry, I.J.5
  • 21
    • 11244269558 scopus 로고    scopus 로고
    • Can we identify metabolically healthy but obese individuals (MHO)?
    • Karelis AD, Brochu M, Rabasa-Lhoret R. Can we identify meta-bolically healthy but obese individuals (MHO)? Diabetes Metab. 2004; 30: 569-572.
    • (2004) Diabetes Metab. , vol.30 , pp. 569-572
    • Karelis, A.D.1    Brochu, M.2    Rabasa-Lhoret, R.3
  • 22
    • 84862581059 scopus 로고    scopus 로고
    • Complement C3: An emerging risk factor in cardiometabolic disease
    • Hertle E, van Greevenbroek MM, Stehouwer CD. Complement C3: an emerging risk factor in cardiometabolic disease. Diabetologia. 2012; 55: 881-884.
    • (2012) Diabetologia , vol.55 , pp. 881-884
    • Hertle, E.1    Van Greevenbroek, M.M.2    Stehouwer, C.D.3
  • 23
    • 33644631393 scopus 로고    scopus 로고
    • Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs obese type 2 diabetes
    • Yang Y, Lu HL, Zhang J, et al. Relationships among acylation stimulating protein, adiponectin and complement C3 in lean vs obese type 2 diabetes. Int J Obes (Lond). 2006; 30: 439-446.
    • (2006) Int J Obes (Lond) , vol.30 , pp. 439-446
    • Yang, Y.1    Lu, H.L.2    Zhang, J.3
  • 24
    • 79955880176 scopus 로고    scopus 로고
    • Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle
    • Masharani UB, Maddux BA, Li X, et al Insulin resistance in non-obese subjects is associated with activation of the JNK pathway and impaired insulin signaling in skeletal muscle. PloS One. 2011; 6: e19878.
    • (2011) PloS One , vol.6
    • Masharani, U.B.1    Maddux, B.A.2    Li, X.3
  • 25
    • 72749099788 scopus 로고    scopus 로고
    • Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome
    • Phillips CM, Goumidi L, Bertrais S., et al Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome. Am J Clin Nutr. 2009; 90: 1665-1673.
    • (2009) Am J Clin Nutr , vol.90 , pp. 1665-1673
    • Phillips, C.M.1    Goumidi, L.2    Bertrais, S.3
  • 26
    • 84855978209 scopus 로고    scopus 로고
    • Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk
    • Phillips CM, Kesse-Guyot E, Ahluwalia N., et al Dietary fat, abdominal obesity and smoking modulate the relationship between plasma complement component 3 concentrations and metabolic syndrome risk. Atherosclerosis. 2012; 220: 513-519.
    • (2012) Atherosclerosis , vol.220 , pp. 513-519
    • Phillips, C.M.1    Kesse-Guyot, E.2    Ahluwalia, N.3
  • 27
    • 0028930107 scopus 로고
    • Association of serum C3 levels with the risk of myocardial infarction
    • Muscari A, Bozzoli C, Puddu G.M., et al Association of serum C3 levels with the risk of myocardial infarction. Am J Med. 1995; 98: 357-364.
    • (1995) Am J Med. , vol.98 , pp. 357-364
    • Muscari, A.1    Bozzoli, C.2    Puddu, G.M.3
  • 28
    • 84855841156 scopus 로고    scopus 로고
    • Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study)
    • van Greevenbroek M.M., Jacobs M, van der Kallen CJ, et al. Human plasma complement C3 is independently associated with coronary heart disease, but only in heavy smokers (the CODAM study). Int J Cardiol. 2012; 154: 158-162.
    • (2012) Int J Cardiol , vol.154 , pp. 158-162
    • Van Greevenbroek, M.M.1    Jacobs, M.2    Van Der Kallen, C.J.3
  • 29
    • 84863101444 scopus 로고    scopus 로고
    • Serum 25-hydroxyvita-min D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years
    • Deleskog A, Piksasova O, Silveira A., et al Serum 25-hydroxyvitamin D concentration, established and emerging cardiovascular risk factors and risk of myocardial infarction before the age of 60 years. Atherosclerosis. 2012; 223: 223-229.
    • (2012) Atherosclerosis , vol.223 , pp. 223-229
    • Deleskog, A.1    Piksasova, O.2    Silveira, A.3
  • 30
    • 77950020199 scopus 로고    scopus 로고
    • The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: The caerphilly study
    • Patterson CC, Smith AE, Yarnell J.W., Rumley A., Ben-Shlomo Y, Lowe GD. The associations of interleukin-6 (IL-6) and downstream inflammatory markers with risk of cardiovascular disease: the Caer-philly Study. Atherosclerosis. 2010; 209: 551-557.
    • (2010) Atherosclerosis , vol.209 , pp. 551-557
    • Patterson, C.C.1    Smith, A.E.2    Yarnell, J.W.3    Rumley, A.4    Ben-Shlomo, Y.5    Lowe, G.D.6
  • 32
    • 84871337477 scopus 로고    scopus 로고
    • Associations of total and high-molecular-weight adiponectin with allcause and cardiovascular mortality in older persons: The cardiovascular health study
    • Kizer JR, Benkeser D, Arnold A.M., et al Associations of total and high-molecular-weight adiponectin with all-cause and cardiovascular mortality in older persons: the Cardiovascular Health Study. Circulation. 2012; 126: 2951-2961.
    • (2012) Circulation , vol.126 , pp. 2951-2961
    • Kizer, J.R.1    Benkeser, D.2    Arnold, A.M.3
  • 33
    • 34547179430 scopus 로고    scopus 로고
    • Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure
    • Wannamethee SG, Whincup PH, Lennon L, Sattar N. Circulating adiponectin levels and mortality in elderly men with and without cardiovascular disease and heart failure. Arch Intern Med. 2007; 167: 1510-1517.
    • (2007) Arch Intern Med. , vol.167 , pp. 1510-1517
    • Wannamethee, S.G.1    Whincup, P.H.2    Lennon, L.3    Sattar, N.4
  • 34
    • 77749242629 scopus 로고    scopus 로고
    • Enhanced metabolic flexibility associated with elevated adiponectin levels
    • Asterholm IW, Scherer PE Enhanced metabolic flexibility associated with elevated adiponectin levels. AmJPathol. 2010; 176: 1364-1376.
    • (2010) AmJPathol , vol.176 , pp. 1364-1376
    • Asterholm, I.W.1    Scherer, P.E.2
  • 36
    • 77956022279 scopus 로고    scopus 로고
    • Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men
    • Meltzer ME, Doggen CJ, de Groot PG, Rosendaal FR, Lisman T. Plasma levels of fibrinolytic proteins and the risk of myocardial infarction in men. Blood. 2010; 116: 529-536.
    • (2010) Blood , vol.116 , pp. 529-536
    • Meltzer, M.E.1    Doggen, C.J.2    De Groot, P.G.3    Rosendaal, F.R.4    Lisman, T.5
  • 37
    • 0032974070 scopus 로고    scopus 로고
    • Fibrinolytic activation markers predict myocardial infarction in the elderly. The cardiovascular health study
    • Cushman M, Lemaitre RN, Kuller L.H., et al Fibrinolytic activation markers predict myocardial infarction in the elderly. The Cardiovascular Health Study. Arterioscler Thromb Vasc Biol. 1999; 19: 493-498.
    • (1999) Arterioscler Thromb Vasc Biol. , vol.19 , pp. 493-498
    • Cushman, M.1    Lemaitre, R.N.2    Kuller, L.H.3
  • 38
    • 79952006216 scopus 로고    scopus 로고
    • The prevalence of metabolically healthy obese subjects defined by BMI and dual-energy x-ray absorptiometry
    • Shea JL, Randell EW, Sun G. The prevalence of metabolically healthy obese subjects defined by BMI and dual-energy x-ray absorptiometry. Obesity (Silver Spring). 2011; 19: 624-630.
    • (2011) Obesity (Silver Spring) , vol.19 , pp. 624-630
    • Shea, J.L.1    Randell, E.W.2    Sun, G.3
  • 39
    • 79951690905 scopus 로고    scopus 로고
    • Impact of BMI and the metabolic syndrome on the risk of diabetes in middleaged men
    • Arnlov J, Sundstrom J, Ingelsson E., Lind L. Impact of BMI and the metabolic syndrome on the risk of diabetes in middleaged men. Diabetes Care. 2011; 34: 61-65.
    • (2011) Diabetes Care , vol.34 , pp. 61-65
    • Arnlov, J.1    Sundstrom, J.2    Ingelsson, E.3    Lind, L.4
  • 40
    • 84863586953 scopus 로고    scopus 로고
    • Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality
    • Hamer M, Stamatakis E. Metabolically healthy obesity and risk of all-cause and cardiovascular disease mortality. J Clin Endocrinol Metab. 2012; 97: 2482-2488.
    • (2012) J Clin Endocrinol Metab. , vol.97 , pp. 2482-2488
    • Hamer, M.1    Stamatakis, E.2
  • 41
    • 84884500573 scopus 로고    scopus 로고
    • Diabetes and cardiovascular disease outcomes in the metabolically healthy obese phenotype: A cohort study
    • Appleton SL, Seaborn CJ, Visvanathan R, et al Diabetes and cardiovascular disease outcomes in the metabolically healthy obese phenotype: a cohort study. Diabetes Care. 2013; 36: 2388-2394.
    • (2013) Diabetes Care , vol.36 , pp. 2388-2394
    • Appleton, S.L.1    Seaborn, C.J.2    Visvanathan, R.3
  • 42
    • 84878490169 scopus 로고    scopus 로고
    • Metabolically healthy but obese, a matter of time? Findings from the prospective pizarra study
    • Soriguer F, Gutierrez-Repiso C, Rubio-Martin E, et al Metabolically healthy but obese, a matter of time? Findings from the prospective Pizarra study. J Clin Endocrinol Metab. 2013; 98: 2318-2325.
    • (2013) J Clin Endocrinol Metab. , vol.98 , pp. 2318-2325
    • Soriguer, F.1    Gutierrez-Repiso, C.2    Rubio-Martin, E.3
  • 43
    • 79953807628 scopus 로고    scopus 로고
    • Effects of a lifestyle intervention in metabolically benign and malign obesity
    • Kantartzis K, Machann J, Schick F., et al Effects of a lifestyle intervention in metabolically benign and malign obesity. Diabetologia. 2011; 54: 864-868.
    • (2011) Diabetologia , vol.54 , pp. 864-868
    • Kantartzis, K.1    Machann, J.2    Schick, F.3
  • 44
    • 84876288287 scopus 로고    scopus 로고
    • Obesity and body fat classification in the metabolic syndrome: Impact on cardiometabolic risk metabotype
    • Phillips CM, Tierney AC, Perez-Martinez P, et al Obesity and body fat classification in the metabolic syndrome: impact on cardiometabolic risk metabotype. Obesity (Silver Spring). 2013; 21: E154-E161.
    • (2013) Obesity (Silver Spring) , vol.21
    • Phillips, C.M.1    Tierney, A.C.2    Perez-Martinez, P.3
  • 45
    • 84876286659 scopus 로고    scopus 로고
    • N-3 polyunsaturated fatty acids: Relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome
    • Robinson LE, Mazurak VC N-3 polyunsaturated fatty acids: relationship to inflammation in healthy adults and adults exhibiting features of metabolic syndrome. Lipids. 2013; 48: 319-332.
    • (2013) Lipids , vol.48 , pp. 319-332
    • Robinson, L.E.1    Mazurak, V.C.2
  • 46
    • 84865086635 scopus 로고    scopus 로고
    • Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA
    • Oliver E, McGillicuddy FC, Harford K.A., et al Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA. J Nutr Biochem. 2012; 23: 1192-1200.
    • (2012) J Nutr Biochem , vol.23 , pp. 1192-1200
    • Oliver, E.1    McGillicuddy, F.C.2    Harford, K.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.