Increased heart failure risk in normal-weight people with metabolic syndrome compared with metabolically healthy obese individuals

Journal of the American College of Cardiology

Volumn 58, Issue 13, 2011, Pages 1343-1350

  Voulgari, Christina ^a   Tentolouris, Nicholas ^a   Dilaveris, Polychronis ^a   Tousoulis, Dimitris ^a   Katsilambros, Nicholas ^a   Stefanadis, Christodoulos ^a  

^a UNIVERSITY OF ATHENS MEDICAL SCHOOL   (Greece)

Author keywords

heart failure; inflammation; lifestyle; metabolic syndrome; obesity

Indexed keywords

C REACTIVE PROTEIN; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL;

ADULT; ARTICLE; BODY MASS; CARDIOVASCULAR RISK; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DISEASE ASSOCIATION; ECHOCARDIOGRAPHY; FEMALE; GLUCOSE BLOOD LEVEL; HEART FAILURE; HEART LEFT VENTRICLE FUNCTION; HEART MUSCLE; HEART PERFORMANCE; HIGH RISK PATIENT; HUMAN; HYPERTENSION; INCIDENCE; INFLAMMATION; INSULIN RESISTANCE; MAJOR CLINICAL STUDY; MALE; METABOLIC SYNDROME X; MICROALBUMINURIA; OBESITY; PRIORITY JOURNAL; RISK FACTOR;

BIOLOGICAL MARKERS; BODY MASS INDEX; CHOLESTEROL; DISEASE PROGRESSION; ECHOCARDIOGRAPHY; FEMALE; FOLLOW-UP STUDIES; GREECE; HEART FAILURE; HEART VENTRICLES; HUMANS; INSULIN; INSULIN RESISTANCE; LIFE STYLE; MALE; METABOLIC SYNDROME X; MIDDLE AGED; MORBIDITY; OBESITY; PROSPECTIVE STUDIES; QUESTIONNAIRES; RISK ASSESSMENT; RISK FACTORS; STROKE VOLUME; TIME FACTORS;

EID: 80053018598     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2011.04.047     Document Type: Article

References (27)

1. R.S. Vasan, and W.B. Kannel Strategies for cardiovascular risk assessment and prevention over the life course: progress amid imperfections Circulation 120 2009 360 363
2. J. Arnlöv, E. Ingelsson, and J. Sundström Impact of body mass index and the metabolic syndrome on the risk of cardiovascular disease and death in middle-aged men Circulation 121 2010 230 236
3. V. Primeau, L. Coderre, and A.D. Karelis Characterizing the profile of obese patients who are metabolically healthy Int J Obes (Lond) 35 2011 971 981
4. G. Calori, G. Lattuada, and L. Piemonti Prevalence, metabolic features and prognosis of metabolically healthy obese Italian individuals: the Cremona Study Diabetes Care 34 2011 210 215
5. I.M. Lee, and R.S. Paffenbarger Jr Design of present day epidemiologic studies of physical activity and health I.M. Lee, Epidemiologic Methods in Physical Activity Studies 2009 Oxford University Press New York, NY 100 123
6. W.L. Haskell, I.M. Lee, R.R. Pate American College of Sports Medicine, American Heart Association Physical activity and public health: updated recommendation for adults from the American College of Sports Medicine and the American Heart Association Circulation 116 2007 1081 1093 (Pubitemid 47329572)
7. D.R. Matthews, J.P. Hosker, and A.S. Rudenski Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man Diabetologia 28 1985 412 419 (Pubitemid 15018832)
8. American Diabetes Association Diabetic nephropathy Diabetes Care 20 Suppl 1 1997 S24 S27
9. Third Report of the National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III) Final Report Circulation 106 2002 3143 3421
10. L.A. Allen, A.F. Hernandez, C.M. O'Connor, and G.M. Felker End points for clinical trials in acute heart failure syndromes J Am Coll Cardiol 53 2009 2248 2258
11. C. Voulgari, I. Moyssakis, and A. Papazafiropoulou The impact of metabolic syndrome on left ventricular myocardial performance Diabetes Metab Res Rev 26 2010 121 127
12. G. Iacobellis, M.C. Ribaudo, and A. Zappaterreno Prevalence of uncomplicated obesity in an Italian obese population Obes Res 13 2005 116 122
13. R.P. Wildman, P. Muntner, and K. Reynolds The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 19992004) Arch Intern Med 168 2008 1617 1624
14. J. Butler, N. Rodondi, Y. Zhu Health ABC Study Metabolic syndrome and the risk of cardiovascular disease in older adults J Am Coll Cardiol 47 2006 1595 1602
15. E. Ingelsson, J. Arnlöv, and L. Lind Metabolic syndrome and risk for heart failure in middle-aged men Heart 92 2006 1409 1413 (Pubitemid 44578829)
16. H. Bahrami, D.A. Bluemke, and R. Kronmal Novel metabolic risk factors for incident heart failure and their relationship with obesity: the MESA (Multi-Ethnic Study of Atherosclerosis) study J Am Coll Cardiol 51 2008 1775 1783 (Pubitemid 351608497)
17. T.B. Horwich, and G.C. Fonarow Glucose, obesity, metabolic syndrome, and diabetes relevance to incidence of heart failure J Am Coll Cardiol 55 2010 283 293
18. C. Voulgari, D. Papadogiannis, and N. Tentolouris Diabetic cardiomyopathy: from the pathophysiology of the cardiac myocytes to current diagnosis and management strategies Vasc Health Risk Manag 6 2010 883 903
19. C. Li, E.S. Ford, and L.C. McGuire Association of metabolic syndrome and insulin resistance with congestive heart failure: findings from the Third National Health and Nutrition Examination Survey J Epidemiol Community Health 61 2007 67 73 (Pubitemid 46114592)
20. J. Arnlöv, L. Lind, and J. Sundström Insulin resistance, dietary fat intake and blood pressure predict left ventricular diastolic function 20 years later Nutr Metab Cardiovasc Dis 15 2005 242 249 (Pubitemid 41190980)
21. R.M. Witteles, and M.B. Fowler Insulin-resistant cardiomyopathy: clinical evidence, mechanisms, and treatment options J Am Coll Cardiol 51 2008 93 102
22. L. van Heerebeek, N. Hamdani, and M.L. Handoko Diastolic stiffness of the failing diabetic heart: importance of fibrosis, advanced glycation end products, and myocyte resting tension Circulation 117 2008 43 51 (Pubitemid 350291180)
23. K.M. Mellor, R.H. Ritchie, and L.M. Delbridge Reactive oxygen species and insulin-resistant cardiomyopathy Clin Exp Pharmacol Physiol 37 2010 222 228
24. N. Tentolouris, S. Liatis, and N. Katsilambros Sympathetic system activity in obesity and metabolic syndrome Ann N Y Acad Sci 1083 2006 129 152 (Pubitemid 44955470)
25. L.S. Szczepaniak, R.G. Victor, and L. Orci Forgotten but not gone: the rediscovery of fatty heart, the most common unrecognized disease in America Circ Res 101 2007 759 767 (Pubitemid 350287190)
26. M. Gentile, S. Panico, and F. Rubba Obesity, overweight, and weight gain over adult life are main determinants of elevated hs-CRP in a cohort of Mediterranean women Eur J Clin Nutr 64 2010 873 878
27. D.S. Frankel, R.S. Vasan, and R.B. D'Agostino Sr. Resistin, adiponectin, and risk of heart failure: the Framingham Offspring study J Am Coll Cardiol 53 2009 754 762