메뉴 건너뛰기




Volumn 77, Issue 3, 2015, Pages 295-303

Type 2 diabetes mellitus: A potentially modifiable risk factor for neurochemical brain changes in bipolar disorders

Author keywords

Bipolar disorder; Global assessment of functioning; N acetylaspartate; Prefrontal cortex; Total creatine; Type 2 diabetes mellitus

Indexed keywords

CREATINE; CREATINE PHOSPHATE; GLUCOSE; INSULIN; N ACETYLASPARTIC ACID; ASPARTIC ACID; N-ACETYLASPARTATE;

EID: 84924667663     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.11.007     Document Type: Article
Times cited : (40)

References (81)
  • 1
    • 50949102049 scopus 로고    scopus 로고
    • Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder
    • Kempton MJ, Geddes JR, Ettinger U, Williams SC, Grasby PM (2008): Meta-analysis, database, and meta-regression of 98 structural imaging studies in bipolar disorder. Arch Gen Psychiatry 65:1017-1032.
    • (2008) Arch Gen Psychiatry , vol.65 , pp. 1017-1032
    • Kempton, M.J.1    Geddes, J.R.2    Ettinger, U.3    Williams, S.C.4    Grasby, P.M.5
  • 2
    • 67349230296 scopus 로고    scopus 로고
    • Amygdala volumes in mood disorders-meta-analysis of magnetic resonance volumetry studies
    • Hajek T, Kopecek M, Kozeny J, Gunde E, Alda M, Hoschl C (2009): Amygdala volumes in mood disorders-meta-analysis of magnetic resonance volumetry studies. J Affect Disord 115:395-410.
    • (2009) J Affect Disord , vol.115 , pp. 395-410
    • Hajek, T.1    Kopecek, M.2    Kozeny, J.3    Gunde, E.4    Alda, M.5    Hoschl, C.6
  • 4
    • 33745264436 scopus 로고    scopus 로고
    • Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: A systematic review of the in vivo proton magnetic resonance spectroscopy findings
    • Yildiz-Yesiloglu A, Ankerst DP (2006): Neurochemical alterations of the brain in bipolar disorder and their implications for pathophysiology: A systematic review of the in vivo proton magnetic resonance spectroscopy findings. Prog Neuropsychopharmacol Biol Psychiatry 30:969-995.
    • (2006) Prog Neuropsychopharmacol Biol Psychiatry , vol.30 , pp. 969-995
    • Yildiz-Yesiloglu, A.1    Ankerst, D.P.2
  • 6
    • 0019303776 scopus 로고
    • Prevalence of diabetes in a manic-depressive population
    • Lilliker SL (1980): Prevalence of diabetes in a manic-depressive population. Compr Psychiatry 21:270-275.
    • (1980) Compr Psychiatry , vol.21 , pp. 270-275
    • Lilliker, S.L.1
  • 7
    • 0032833128 scopus 로고    scopus 로고
    • Elevated frequency of diabetes mellitus in hospitalized manic-depressive patients
    • Cassidy F, Ahearn E, Carrol BJ (1999): Elevated frequency of diabetes mellitus in hospitalized manic-depressive patients. Am J Psychiatry 156:1417-1420.
    • (1999) Am J Psychiatry , vol.156 , pp. 1417-1420
    • Cassidy, F.1    Ahearn, E.2    Carrol, B.J.3
  • 9
    • 84883548037 scopus 로고    scopus 로고
    • Comorbidities and mortality in bipolar disorder: A Swedish National Cohort Study
    • Crump C, Sundquist K, Winkleby MA, Sundquist J (2013): Comorbidities and mortality in bipolar disorder: A Swedish National Cohort Study. JAMA Psychiatry 70:931-939.
    • (2013) JAMA Psychiatry , vol.70 , pp. 931-939
    • Crump, C.1    Sundquist, K.2    Winkleby, M.A.3    Sundquist, J.4
  • 10
    • 22044436909 scopus 로고    scopus 로고
    • Bipolar disorder and diabetes mellitus: Epidemiology, etiology, and treatment implications
    • McIntyre RS, Konarski JZ, Misener VL, Kennedy SH (2005): Bipolar disorder and diabetes mellitus: Epidemiology, etiology, and treatment implications. Ann Clin Psychiatry 17:83-93.
    • (2005) Ann Clin Psychiatry , vol.17 , pp. 83-93
    • McIntyre, R.S.1    Konarski, J.Z.2    Misener, V.L.3    Kennedy, S.H.4
  • 11
    • 20344401107 scopus 로고    scopus 로고
    • Clinical correlates of current level of functioning in primary care-treated bipolar patients
    • Hajek T, Slaney C, Garnham J, Ruzickova M, Passmore M, Alda M (2005): Clinical correlates of current level of functioning in primary care-treated bipolar patients. Bipolar Disord 7:286-291.
    • (2005) Bipolar Disord , vol.7 , pp. 286-291
    • Hajek, T.1    Slaney, C.2    Garnham, J.3    Ruzickova, M.4    Passmore, M.5    Alda, M.6
  • 12
    • 42949119173 scopus 로고    scopus 로고
    • Rapid cycling bipolar disorders in primary and tertiary care treated patients
    • Hajek T, Hahn M, Slaney C, Garnham J, Green J, Ruzickova M, et al. (2008): Rapid cycling bipolar disorders in primary and tertiary care treated patients. Bipolar Disord 10:495-502.
    • (2008) Bipolar Disord , vol.10 , pp. 495-502
    • Hajek, T.1    Hahn, M.2    Slaney, C.3    Garnham, J.4    Green, J.5    Ruzickova, M.6
  • 13
    • 0142090422 scopus 로고    scopus 로고
    • Clinical features of bipolar disorder with and without comorbid diabetes mellitus
    • Ruzickova M, Slaney C, Garnham J, Alda M (2003): Clinical features of bipolar disorder with and without comorbid diabetes mellitus. Can J Psychiatry 48:458-461.
    • (2003) Can J Psychiatry , vol.48 , pp. 458-461
    • Ruzickova, M.1    Slaney, C.2    Garnham, J.3    Alda, M.4
  • 15
    • 67650466009 scopus 로고    scopus 로고
    • Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder
    • Laursen TM, Munk-Olsen T, Agerbo E, Gasse C, Mortensen PB (2009): Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder. Arch Gen Psychiatry 66:713-720.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 713-720
    • Laursen, T.M.1    Munk-Olsen, T.2    Agerbo, E.3    Gasse, C.4    Mortensen, P.B.5
  • 18
    • 33745268502 scopus 로고    scopus 로고
    • Extent and management of cardiovascular risk factors in patients with type 2 diabetes and serious mental illness
    • Kreyenbuhl J, Dickerson FB, Medoff DR, Brown CH, Goldberg RW, Fang L, et al. (2006): Extent and management of cardiovascular risk factors in patients with type 2 diabetes and serious mental illness. J Nerv Ment Dis 194:404-410.
    • (2006) J Nerv Ment Dis , vol.194 , pp. 404-410
    • Kreyenbuhl, J.1    Dickerson, F.B.2    Medoff, D.R.3    Brown, C.H.4    Goldberg, R.W.5    Fang, L.6
  • 20
    • 70349581633 scopus 로고    scopus 로고
    • Insulin resistance and Alzheimer's disease
    • de la Monte SM (2009): Insulin resistance and Alzheimer's disease. BMB Rep 42:475-481.
    • (2009) BMB Rep , vol.42 , pp. 475-481
    • De La Monte, S.M.1
  • 22
    • 4143110556 scopus 로고    scopus 로고
    • Oxidative stress in the pathogenesis of diabetic neuropathy
    • Vincent AM, Russell JW, Low P, Feldman EL (2004): Oxidative stress in the pathogenesis of diabetic neuropathy. Endocr Rev 25:612-628.
    • (2004) Endocr Rev , vol.25 , pp. 612-628
    • Vincent, A.M.1    Russell, J.W.2    Low, P.3    Feldman, E.L.4
  • 23
    • 41949114990 scopus 로고    scopus 로고
    • Role of mitochondrial dysfunction in insulin resistance
    • Kim JA, Wei Y, Sowers JR (2008): Role of mitochondrial dysfunction in insulin resistance. Circ Res 102:401-414.
    • (2008) Circ Res , vol.102 , pp. 401-414
    • Kim, J.A.1    Wei, Y.2    Sowers, J.R.3
  • 25
    • 84874070358 scopus 로고    scopus 로고
    • Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy
    • Liu Q, Li J, Cheng R, Chen Y, Lee K, Hu Y, et al. (2013): Nitrosative stress plays an important role in Wnt pathway activation in diabetic retinopathy. Antioxid Redox Signal 18:1141-1153.
    • (2013) Antioxid Redox Signal , vol.18 , pp. 1141-1153
    • Liu, Q.1    Li, J.2    Cheng, R.3    Chen, Y.4    Lee, K.5    Hu, Y.6
  • 26
    • 44449131492 scopus 로고    scopus 로고
    • Diabetes increases atrophy and vascular lesions on brain MRI in patients with symptomatic arterial disease
    • Tiehuis AM, van der GY, Visseren FL, Vincken KL, Biessels GJ, Appelman AP, et al. (2008): Diabetes increases atrophy and vascular lesions on brain MRI in patients with symptomatic arterial disease. Stroke 39:1600-1603.
    • (2008) Stroke , vol.39 , pp. 1600-1603
    • Tiehuis, A.M.1    Van Der, G.Y.2    Visseren, F.L.3    Vincken, K.L.4    Biessels, G.J.5    Appelman, A.P.6
  • 27
    • 67650138159 scopus 로고    scopus 로고
    • Cognitive dysfunction and its clinical and radiological determinants in patients with symptomatic arterial disease and diabetes
    • Tiehuis AM, Mali WP, van Raamt AF, Visseren FL, Biessels GJ, van Zandvoort MJ, et al. (2009): Cognitive dysfunction and its clinical and radiological determinants in patients with symptomatic arterial disease and diabetes. J Neurol Sci 283:170-174.
    • (2009) J Neurol Sci , vol.283 , pp. 170-174
    • Tiehuis, A.M.1    Mali, W.P.2    Van Raamt, A.F.3    Visseren, F.L.4    Biessels, G.J.5    Van Zandvoort, M.J.6
  • 28
    • 67649421600 scopus 로고    scopus 로고
    • Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus
    • Bruehl H, Wolf OT, Sweat V, Tirsi A, Richardson S, Convit A (2009): Modifiers of cognitive function and brain structure in middle-aged and elderly individuals with type 2 diabetes mellitus. Brain Res 1280:186-194.
    • (2009) Brain Res , vol.1280 , pp. 186-194
    • Bruehl, H.1    Wolf, O.T.2    Sweat, V.3    Tirsi, A.4    Richardson, S.5    Convit, A.6
  • 30
    • 33847652525 scopus 로고    scopus 로고
    • Hippocampal damage and memory impairments as possible early brain complications of type 2 diabetes
    • Gold SM, Dziobek I, Sweat V, Tirsi A, Rogers K, Bruehl H, et al. (2007): Hippocampal damage and memory impairments as possible early brain complications of type 2 diabetes. Diabetologia 50:711-719.
    • (2007) Diabetologia , vol.50 , pp. 711-719
    • Gold, S.M.1    Dziobek, I.2    Sweat, V.3    Tirsi, A.4    Rogers, K.5    Bruehl, H.6
  • 31
    • 33845462866 scopus 로고    scopus 로고
    • Brain aging in very old men with type 2 diabetes: The Honolulu-Asia Aging Study
    • Korf ES, White LR, Scheltens P, Launer LJ (2006): Brain aging in very old men with type 2 diabetes: The Honolulu-Asia Aging Study. Diabetes Care 29:2268-2274.
    • (2006) Diabetes Care , vol.29 , pp. 2268-2274
    • Korf, E.S.1    White, L.R.2    Scheltens, P.3    Launer, L.J.4
  • 32
    • 64249121164 scopus 로고    scopus 로고
    • A look inside the diabetic brain: Contributors to diabetes-induced brain aging
    • Wrighten SA, Piroli GG, Grillo CA, Reagan LP (2009): A look inside the diabetic brain: Contributors to diabetes-induced brain aging. Biochim Biophys Acta 1792:444-453.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 444-453
    • Wrighten, S.A.1    Piroli, G.G.2    Grillo, C.A.3    Reagan, L.P.4
  • 33
    • 0026773392 scopus 로고
    • Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: Detection with proton MR spectroscopy
    • Kreis R, Ross BD (1992): Cerebral metabolic disturbances in patients with subacute and chronic diabetes mellitus: Detection with proton MR spectroscopy. Radiology 184:123-130.
    • (1992) Radiology , vol.184 , pp. 123-130
    • Kreis, R.1    Ross, B.D.2
  • 34
    • 0034923254 scopus 로고    scopus 로고
    • In vivo proton MR spectroscopy of chorea-ballismus in diabetes mellitus
    • Lai PH, Chen PC, Chang MH, Pan HB, Yang CF, Wu MT, et al. (2001): In vivo proton MR spectroscopy of chorea-ballismus in diabetes mellitus. Neuroradiology 43:525-531.
    • (2001) Neuroradiology , vol.43 , pp. 525-531
    • Lai, P.H.1    Chen, P.C.2    Chang, M.H.3    Pan, H.B.4    Yang, C.F.5    Wu, M.T.6
  • 36
    • 23144432419 scopus 로고    scopus 로고
    • Brain metabolite changes on proton magnetic resonance spectroscopy in children with poorly controlled type 1 diabetes mellitus
    • Sarac K, Akinci A, Alkan A, Aslan M, Baysal T, Ozcan C (2005): Brain metabolite changes on proton magnetic resonance spectroscopy in children with poorly controlled type 1 diabetes mellitus. Neuroradiology 47:562-565.
    • (2005) Neuroradiology , vol.47 , pp. 562-565
    • Sarac, K.1    Akinci, A.2    Alkan, A.3    Aslan, M.4    Baysal, T.5    Ozcan, C.6
  • 37
    • 84861642044 scopus 로고    scopus 로고
    • Evaluation of metabolite changes in visual cortex in diabetic retinopathy by MRspectroscopy
    • Ozsoy E, Doganay S, Dogan M, Alkan A, Firat PG (2012): Evaluation of metabolite changes in visual cortex in diabetic retinopathy by MRspectroscopy. J Diabetes Complications 26:241-245.
    • (2012) J Diabetes Complications , vol.26 , pp. 241-245
    • Ozsoy, E.1    Doganay, S.2    Dogan, M.3    Alkan, A.4    Firat, P.G.5
  • 38
    • 45849119076 scopus 로고    scopus 로고
    • Evaluation of in vivo cerebral metabolism on proton magnetic resonance spectroscopy in patients with impaired glucose tolerance and type 2 diabetes mellitus
    • Sahin I, Alkan A, Keskin L, Cikim A, Karakas HM, Firat AK, Sigirci A (2008): Evaluation of in vivo cerebral metabolism on proton magnetic resonance spectroscopy in patients with impaired glucose tolerance and type 2 diabetes mellitus. J Diabetes Complications 22:254-260.
    • (2008) J Diabetes Complications , vol.22 , pp. 254-260
    • Sahin, I.1    Alkan, A.2    Keskin, L.3    Cikim, A.4    Karakas, H.M.5    Firat, A.K.6    Sigirci, A.7
  • 39
    • 0018119373 scopus 로고
    • A diagnostic interview: The schedule for affective disorders and schizophrenia
    • Endicott J, Spitzer RL (1978): A diagnostic interview: The schedule for affective disorders and schizophrenia. Arch Gen Psychiatry 35:837-844.
    • (1978) Arch Gen Psychiatry , vol.35 , pp. 837-844
    • Endicott, J.1    Spitzer, R.L.2
  • 40
    • 0022391220 scopus 로고
    • The longitudinal course of recurrent affective illness: Life chart data from research patients at the NIMH
    • Roy-Byrne P, Post RM, Uhde TW, Porcu T, Davis D (1985): The longitudinal course of recurrent affective illness: Life chart data from research patients at the NIMH. Acta Psychiatr Scand Suppl 317:1-34.
    • (1985) Acta Psychiatr Scand Suppl , vol.317 , pp. 1-34
    • Roy-Byrne, P.1    Post, R.M.2    Uhde, T.W.3    Porcu, T.4    Davis, D.5
  • 41
    • 0016970988 scopus 로고
    • The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance
    • Endicott J, Spitzer RL, Fleiss JL, Cohen J (1976): The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance. Arch Gen Psychiatry 33:766-771.
    • (1976) Arch Gen Psychiatry , vol.33 , pp. 766-771
    • Endicott, J.1    Spitzer, R.L.2    Fleiss, J.L.3    Cohen, J.4
  • 42
    • 28444489368 scopus 로고    scopus 로고
    • The childhood experience of care and abuse questionnaire (CECA.Q): Validation in a community series
    • Bifulco A, Bernazzani O, Moran PM, Jacobs C (2005): The childhood experience of care and abuse questionnaire (CECA.Q): Validation in a community series. Br J Clin Psychol 44:563-581.
    • (2005) Br J Clin Psychol , vol.44 , pp. 563-581
    • Bifulco, A.1    Bernazzani, O.2    Moran, P.M.3    Jacobs, C.4
  • 43
    • 75149130955 scopus 로고    scopus 로고
    • Diagnosis and classification of diabetes mellitus
    • American Diabetes Association (2010): Diagnosis and classification of diabetes mellitus. Diabetes Care 33(suppl 1):S62-S69.
    • (2010) Diabetes Care , vol.33 , pp. S62-S69
    • American Diabetes Association1
  • 45
    • 0035142725 scopus 로고    scopus 로고
    • Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes
    • Katsuki A, Sumida Y, Gabazza EC, Murashima S, Furuta M, Araki-Sasaki R, et al. (2001): Homeostasis model assessment is a reliable indicator of insulin resistance during follow-up of patients with type 2 diabetes. Diabetes Care 24:362-365.
    • (2001) Diabetes Care , vol.24 , pp. 362-365
    • Katsuki, A.1    Sumida, Y.2    Gabazza, E.C.3    Murashima, S.4    Furuta, M.5    Araki-Sasaki, R.6
  • 46
    • 66949167449 scopus 로고    scopus 로고
    • Significance of an index of insulin resistance in non-diabetic patients with impaired fasting glucose with acute myocardial infarction and its correlation to short term outcome
    • Sinha DP, Ahmed S, Baneerjee AK, Das M, Hassan H (2009): Significance of an index of insulin resistance in non-diabetic patients with impaired fasting glucose with acute myocardial infarction and its correlation to short term outcome. Indian Heart J 61:40-43.
    • (2009) Indian Heart J , vol.61 , pp. 40-43
    • Sinha, D.P.1    Ahmed, S.2    Baneerjee, A.K.3    Das, M.4    Hassan, H.5
  • 47
    • 56349170832 scopus 로고    scopus 로고
    • A comparison of affected and unaffected relatives of patients with bipolar disorder using proton magnetic resonance spectroscopy
    • Hajek T, Bernier D, Slaney C, Propper L, Schmidt M, Carrey N, et al. (2008): A comparison of affected and unaffected relatives of patients with bipolar disorder using proton magnetic resonance spectroscopy. J Psychiatry Neurosci 33:531-540.
    • (2008) J Psychiatry Neurosci , vol.33 , pp. 531-540
    • Hajek, T.1    Bernier, D.2    Slaney, C.3    Propper, L.4    Schmidt, M.5    Carrey, N.6
  • 48
    • 84860515845 scopus 로고    scopus 로고
    • Large positive effect of lithium on prefrontal cortex Nacetylaspartate in patients with bipolar disorder: 2-centre study
    • Hajek T, Bauer M, Pfennig A, Cullis J, Ploch J, O'Donovan C, et al. (2012): Large positive effect of lithium on prefrontal cortex Nacetylaspartate in patients with bipolar disorder: 2-centre study. J Psychiatry Neurosci 37:185-192.
    • (2012) J Psychiatry Neurosci , vol.37 , pp. 185-192
    • Hajek, T.1    Bauer, M.2    Pfennig, A.3    Cullis, J.4    Ploch, J.5    O'Donovan, C.6
  • 49
    • 0142042993 scopus 로고    scopus 로고
    • Neurobiology of emotion perception II: Implications for major psychiatric disorders
    • Phillips ML, Drevets WC, Rauch SL, Lane R (2003): Neurobiology of emotion perception II: Implications for major psychiatric disorders. Biol Psychiatry 54:515-528.
    • (2003) Biol Psychiatry , vol.54 , pp. 515-528
    • Phillips, M.L.1    Drevets, W.C.2    Rauch, S.L.3    Lane, R.4
  • 50
    • 84865334768 scopus 로고    scopus 로고
    • Overlapping prefrontal systems involved in cognitive and emotional processing in euthymic bipolar disorder and following sleep deprivation: A review of functional neuroimaging studies
    • McKenna BS, Eyler LT (2012): Overlapping prefrontal systems involved in cognitive and emotional processing in euthymic bipolar disorder and following sleep deprivation: A review of functional neuroimaging studies. Clin Psychol Rev 32:650-663.
    • (2012) Clin Psychol Rev , vol.32 , pp. 650-663
    • McKenna, B.S.1    Eyler, L.T.2
  • 51
    • 0037250207 scopus 로고    scopus 로고
    • Modulating dysfunctional limbic-cortical circuits in depression: Towards development of brain-based algorithms for diagnosis and optimised treatment
    • Mayberg HS (2003): Modulating dysfunctional limbic-cortical circuits in depression: Towards development of brain-based algorithms for diagnosis and optimised treatment. Br Med Bull 65:193-207.
    • (2003) Br Med Bull , vol.65 , pp. 193-207
    • Mayberg, H.S.1
  • 52
    • 34247620292 scopus 로고    scopus 로고
    • Neurocognitive test performance predicts functional recovery from acute exacerbation leading to hospitalization in bipolar disorder
    • Jaeger J, Berns S, Loftus S, Gonzalez C, Czobor P (2007): Neurocognitive test performance predicts functional recovery from acute exacerbation leading to hospitalization in bipolar disorder. Bipolar Disord 9:93-102.
    • (2007) Bipolar Disord , vol.9 , pp. 93-102
    • Jaeger, J.1    Berns, S.2    Loftus, S.3    Gonzalez, C.4    Czobor, P.5
  • 53
    • 0034959727 scopus 로고    scopus 로고
    • Automatic quantitation of localized in vivo 1H spectra with LCModel
    • Provencher SW (2001): Automatic quantitation of localized in vivo 1H spectra with LCModel. NMR Biomed 14:260-264.
    • (2001) NMR Biomed , vol.14 , pp. 260-264
    • Provencher, S.W.1
  • 54
    • 0037561211 scopus 로고    scopus 로고
    • Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla
    • Gruber S, Frey R, Mlynarik V, Stadlbauer A, Heiden A, Kasper S, et al. (2003): Quantification of metabolic differences in the frontal brain of depressive patients and controls obtained by 1H-MRS at 3 Tesla. Invest Radiol 38:403-408.
    • (2003) Invest Radiol , vol.38 , pp. 403-408
    • Gruber, S.1    Frey, R.2    Mlynarik, V.3    Stadlbauer, A.4    Heiden, A.5    Kasper, S.6
  • 56
    • 84890108686 scopus 로고    scopus 로고
    • Making progress with magnetic resonance spectroscopy
    • published online ahead of print October 9
    • Ongur D (2013): Making progress with magnetic resonance spectroscopy [published online ahead of print October 9]. JAMA Psychiatry.
    • (2013) JAMA Psychiatry
    • Ongur, D.1
  • 57
    • 27144492384 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder: Evidence from magnetic resonance spectroscopy research
    • Stork C, Renshaw PF (2005): Mitochondrial dysfunction in bipolar disorder: Evidence from magnetic resonance spectroscopy research. Mol Psychiatry 10:900-919.
    • (2005) Mol Psychiatry , vol.10 , pp. 900-919
    • Stork, C.1    Renshaw, P.F.2
  • 58
    • 34548621218 scopus 로고    scopus 로고
    • Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: An in vivo 1H MRS study
    • Frey BN, Stanley JA, Nery FG, Monkul ES, Nicoletti MA, Chen HH, et al. (2007): Abnormal cellular energy and phospholipid metabolism in the left dorsolateral prefrontal cortex of medication-free individuals with bipolar disorder: An in vivo 1H MRS study. Bipolar Disord 9(suppl 1):119-127.
    • (2007) Bipolar Disord , vol.9 , pp. 119-127
    • Frey, B.N.1    Stanley, J.A.2    Nery, F.G.3    Monkul, E.S.4    Nicoletti, M.A.5    Chen, H.H.6
  • 59
    • 0032977724 scopus 로고    scopus 로고
    • Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder
    • Hamakawa H, Kato T, Shioiri T, Inubushi T, Kato N (1999): Quantitative proton magnetic resonance spectroscopy of the bilateral frontal lobes in patients with bipolar disorder. Psychol Med 29:639-644.
    • (1999) Psychol Med , vol.29 , pp. 639-644
    • Hamakawa, H.1    Kato, T.2    Shioiri, T.3    Inubushi, T.4    Kato, N.5
  • 60
    • 0038521214 scopus 로고    scopus 로고
    • Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder
    • Deicken RF, Pegues MP, Anzalone S, Feiwell R, Soher B (2003): Lower concentration of hippocampal N-acetylaspartate in familial bipolar I disorder. Am J Psychiatry 160:873-882.
    • (2003) Am J Psychiatry , vol.160 , pp. 873-882
    • Deicken, R.F.1    Pegues, M.P.2    Anzalone, S.3    Feiwell, R.4    Soher, B.5
  • 62
    • 84883733870 scopus 로고    scopus 로고
    • Molecular links between Alzheimer's disease and diabetes mellitus
    • Yang Y, Song W (2013): Molecular links between Alzheimer's disease and diabetes mellitus. Neuroscience 250C:140-150.
    • (2013) Neuroscience , vol.250 C , pp. 140-150
    • Yang, Y.1    Song, W.2
  • 64
    • 0034280096 scopus 로고    scopus 로고
    • Mitochondrial dysfunction in bipolar disorder
    • Kato T, Kato N (2000): Mitochondrial dysfunction in bipolar disorder. Bipolar Disord 2:180-190.
    • (2000) Bipolar Disord , vol.2 , pp. 180-190
    • Kato, T.1    Kato, N.2
  • 65
    • 77950575478 scopus 로고    scopus 로고
    • Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder
    • Andreazza AC, Shao L, Wang JF, Young LT (2010): Mitochondrial complex I activity and oxidative damage to mitochondrial proteins in the prefrontal cortex of patients with bipolar disorder. Arch Gen Psychiatry 67:360-368.
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 360-368
    • Andreazza, A.C.1    Shao, L.2    Wang, J.F.3    Young, L.T.4
  • 66
    • 82455162414 scopus 로고    scopus 로고
    • Decreased mRNA expression of uncoupling protein 2, a mitochondrial proton transporter, in post-mortem prefrontal cortex from patients with bipolar disorder and schizophrenia
    • Gigante AD, Andreazza AC, Lafer B, Yatham LN, Beasley CL, Young LT (2011): Decreased mRNA expression of uncoupling protein 2, a mitochondrial proton transporter, in post-mortem prefrontal cortex from patients with bipolar disorder and schizophrenia. Neurosci Lett 505:47-51.
    • (2011) Neurosci Lett , vol.505 , pp. 47-51
    • Gigante, A.D.1    Andreazza, A.C.2    Lafer, B.3    Yatham, L.N.4    Beasley, C.L.5    Young, L.T.6
  • 68
    • 0033667655 scopus 로고    scopus 로고
    • Non-invasive methods for studying brain energy metabolism: What they show and what it means
    • Kemp GJ (2000): Non-invasive methods for studying brain energy metabolism: What they show and what it means. Dev Neurosci 22:418-428.
    • (2000) Dev Neurosci , vol.22 , pp. 418-428
    • Kemp, G.J.1
  • 70
    • 84874535427 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, pandemic in 21st century
    • Ginter E, Simko V (2012): Type 2 diabetes mellitus, pandemic in 21st century. Adv Exp Med Biol 771:42-50.
    • (2012) Adv Exp Med Biol , vol.771 , pp. 42-50
    • Ginter, E.1    Simko, V.2
  • 71
    • 44849127652 scopus 로고    scopus 로고
    • Body mass index and magnetic resonance markers of brain integrity in adults
    • Gazdzinski S, Kornak J, Weiner MW, Meyerhoff DJ (2008): Body mass index and magnetic resonance markers of brain integrity in adults. Ann Neurol 63:652-657.
    • (2008) Ann Neurol , vol.63 , pp. 652-657
    • Gazdzinski, S.1    Kornak, J.2    Weiner, M.W.3    Meyerhoff, D.J.4
  • 73
    • 79960847095 scopus 로고    scopus 로고
    • The association of elevated body mass index with reduced brain volumes in first-episode mania
    • Bond DJ, Lang DJ, Noronha MM, Kunz M, Torres IJ, Su W, et al. (2011): The association of elevated body mass index with reduced brain volumes in first-episode mania. Biol Psychiatry 70:381-387.
    • (2011) Biol Psychiatry , vol.70 , pp. 381-387
    • Bond, D.J.1    Lang, D.J.2    Noronha, M.M.3    Kunz, M.4    Torres, I.J.5    Su, W.6
  • 74
    • 80052829864 scopus 로고    scopus 로고
    • Chronic somatic comorbidity and excess mortality due to natural causes in persons with schizophrenia or bipolar affective disorder
    • Laursen TM, Munk-Olsen T, Gasse C (2011): Chronic somatic comorbidity and excess mortality due to natural causes in persons with schizophrenia or bipolar affective disorder. PLoS One 6:e24597.
    • (2011) PLoS One , vol.6 , pp. e24597
    • Laursen, T.M.1    Munk-Olsen, T.2    Gasse, C.3
  • 75
    • 75749148025 scopus 로고    scopus 로고
    • A randomized trial of medical care management for community mental health settings: The Primary Care Access, Referral, and Evaluation (PCARE) study
    • Druss BG, von Esenwein SA, Compton MT, Rask KJ, Zhao L, Parker RM (2010): A randomized trial of medical care management for community mental health settings: The Primary Care Access, Referral, and Evaluation (PCARE) study. Am J Psychiatry 167:151-159.
    • (2010) Am J Psychiatry , vol.167 , pp. 151-159
    • Druss, B.G.1    Von Esenwein, S.A.2    Compton, M.T.3    Rask, K.J.4    Zhao, L.5    Parker, R.M.6
  • 76
    • 80053087842 scopus 로고    scopus 로고
    • Management of patients with type 2 diabetes
    • Nelson SE (2011): Management of patients with type 2 diabetes. Curr Med Res Opin 27:1931-1947.
    • (2011) Curr Med Res Opin , vol.27 , pp. 1931-1947
    • Nelson, S.E.1
  • 77
    • 32844472127 scopus 로고    scopus 로고
    • Cure therapeutics and strategic prevention: Raising the bar for mental health research
    • Insel TR, Scolnick EM (2006): Cure therapeutics and strategic prevention: Raising the bar for mental health research. Mol Psychiatry 11:11-17.
    • (2006) Mol Psychiatry , vol.11 , pp. 11-17
    • Insel, T.R.1    Scolnick, E.M.2
  • 79
    • 34249079805 scopus 로고    scopus 로고
    • Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy
    • Ajilore O, Haroon E, Kumaran S, Darwin C, Binesh N, Mintz J, et al. (2007): Measurement of brain metabolites in patients with type 2 diabetes and major depression using proton magnetic resonance spectroscopy. Neuropsychopharmacology 32:1224-1231.
    • (2007) Neuropsychopharmacology , vol.32 , pp. 1224-1231
    • Ajilore, O.1    Haroon, E.2    Kumaran, S.3    Darwin, C.4    Binesh, N.5    Mintz, J.6
  • 80
    • 0027450301 scopus 로고
    • Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types
    • Urenjak J, Williams SR, Gadian DG, Noble M (1993): Proton nuclear magnetic resonance spectroscopy unambiguously identifies different neural cell types. J Neurosci 13:981-989.
    • (1993) J Neurosci , vol.13 , pp. 981-989
    • Urenjak, J.1    Williams, S.R.2    Gadian, D.G.3    Noble, M.4
  • 81
    • 33745643161 scopus 로고    scopus 로고
    • Neurochemical effects of olanzapine in first-hospitalization manic adolescents: A proton magnetic resonance spectroscopy study
    • DelBello MP, Cecil KM, Adler CM, Daniels JP, Strakowski SM (2006): Neurochemical effects of olanzapine in first-hospitalization manic adolescents: A proton magnetic resonance spectroscopy study. Neuropsychopharmacology 31:1264-1273.
    • (2006) Neuropsychopharmacology , vol.31 , pp. 1264-1273
    • DelBello, M.P.1    Cecil, K.M.2    Adler, C.M.3    Daniels, J.P.4    Strakowski, S.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.