-
1
-
-
0024510510
-
Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: Long-term follow-up of a controlled trial
-
Storb R, Deeg HJ, Pepe M, et al. Methotrexate and cyclosporine versus cyclosporine alone for prophylaxis of graft-versus-host disease in patients given HLA-identical marrow grafts for leukemia: long-term follow-up of a controlled trial. Blood 1989;73:1729-1734.
-
(1989)
Blood
, vol.73
, pp. 1729-1734
-
-
Storb, R.1
Deeg, H.J.2
Pepe, M.3
-
2
-
-
0022470379
-
Marrow transplantation for severe aplastic anemia: Methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of acute graft-versus-host disease
-
Storb R, Deeg HJ, Farewell V, et al. Marrow transplantation for severe aplastic anemia: methotrexate alone compared with a combination of methotrexate and cyclosporine for prevention of acute graft-versus-host disease. Blood 1986;68:119-125.
-
(1986)
Blood
, vol.68
, pp. 119-125
-
-
Storb, R.1
Deeg, H.J.2
Farewell, V.3
-
3
-
-
0034665674
-
Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors
-
Nash RA, Antin JH, Karanes C, et al. Phase 3 study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. Blood 2000;96:2062-2068.
-
(2000)
Blood
, vol.96
, pp. 2062-2068
-
-
Nash, R.A.1
Antin, J.H.2
Karanes, C.3
-
4
-
-
79958724985
-
A retrospective comparison of tacrolimus versus cyclosporine with methotrexate for immunosuppression after allogeneic hematopoietic cell transplantation with mobilized blood cells
-
Inamoto Y, Flowers ME, Appelbaum FR, et al. A retrospective comparison of tacrolimus versus cyclosporine with methotrexate for immunosuppression after allogeneic hematopoietic cell transplantation with mobilized blood cells. Biol Blood Marrow Transplant 2011;17:1088-1092.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 1088-1092
-
-
Inamoto, Y.1
Flowers, M.E.2
Appelbaum, F.R.3
-
5
-
-
20444373376
-
Rapamycin selectively expands CD4 + CD25 + FoxP3 + regulatory T cells
-
Battaglia M, Stabilini A, Roncarolo MG. Rapamycin selectively expands CD4 + CD25 + FoxP3 + regulatory T cells. Blood 2005;105:4743-4748.
-
(2005)
Blood
, vol.105
, pp. 4743-4748
-
-
Battaglia, M.1
Stabilini, A.2
Roncarolo, M.G.3
-
6
-
-
38049177784
-
Differential impact of mammalian target of rapamycin inhibition on CD4 + CD25 + Foxp3 + regulatory T cells compared with conventional CD4 + T cells
-
Zeiser R, Leveson-Gower DB, Zambricki EA, et al. Differential impact of mammalian target of rapamycin inhibition on CD4 + CD25 + Foxp3 + regulatory T cells compared with conventional CD4 + T cells. Blood 2008;111:453-462.
-
(2008)
Blood
, vol.111
, pp. 453-462
-
-
Zeiser, R.1
Leveson-Gower, D.B.2
Zambricki, E.A.3
-
7
-
-
84870455529
-
A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation
-
Pidala J, Kim J, Jim H, et al. A randomized phase II study to evaluate tacrolimus in combination with sirolimus or methotrexate after allogeneic hematopoietic cell transplantation. Haematologica 2012;97:1882-1889.
-
(2012)
Haematologica
, vol.97
, pp. 1882-1889
-
-
Pidala, J.1
Kim, J.2
Jim, H.3
-
8
-
-
84875680385
-
The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate
-
Perez-Simon JA, Martino R, Parody R, et al. The combination of sirolimus plus tacrolimus improves outcome after reduced-intensity conditioning, unrelated donor hematopoietic stem cell transplantation compared with cyclosporine plus mycofenolate. Haematologica 2013;98:526-532.
-
(2013)
Haematologica
, vol.98
, pp. 526-532
-
-
Perez-Simon, J.A.1
Martino, R.2
Parody, R.3
-
9
-
-
20044396552
-
Activity of sirolimus in patients with myelodysplastic syndrome - Results of a pilot study
-
Platzbecker U, Haase M, Herbst R, et al. Activity of sirolimus in patients with myelodysplastic syndrome - results of a pilot study. Br J Haematol 2005;128:625-630.
-
(2005)
Br J Haematol
, vol.128
, pp. 625-630
-
-
Platzbecker, U.1
Haase, M.2
Herbst, R.3
-
10
-
-
20144363954
-
Antileukemic activity of rapamycin in acute myeloid leukemia
-
Recher C, Beyne-Rauzy O, Demur C, et al. Antileukemic activity of rapamycin in acute myeloid leukemia. Blood 2005;105:2527-2534.
-
(2005)
Blood
, vol.105
, pp. 2527-2534
-
-
Recher, C.1
Beyne-Rauzy, O.2
Demur, C.3
-
11
-
-
34347369749
-
Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia
-
Chan SM, Weng AP, Tibshirani R, et al. Notch signals positively regulate activity of the mTOR pathway in T-cell acute lymphoblastic leukemia. Blood 2007;110:278-286.
-
(2007)
Blood
, vol.110
, pp. 278-286
-
-
Chan, S.M.1
Weng, A.P.2
Tibshirani, R.3
-
12
-
-
33745909399
-
Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies
-
Witzig TE, Kaufmann SH. Inhibition of the phosphatidylinositol 3-kinase/mammalian target of rapamycin pathway in hematologic malignancies. Curr Treat Options Oncol 2006;7:285-294.
-
(2006)
Curr Treat Options Oncol
, vol.7
, pp. 285-294
-
-
Witzig, T.E.1
Kaufmann, S.H.2
-
13
-
-
12744279721
-
Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: A new therapeutic option
-
Ringshausen I, Peschel C, Decker T. Mammalian target of rapamycin (mTOR) inhibition in chronic lymphocytic B-cell leukemia: a new therapeutic option. Leuk Lymphoma 2005;46:11-19.
-
(2005)
Leuk Lymphoma
, vol.46
, pp. 11-19
-
-
Ringshausen, I.1
Peschel, C.2
Decker, T.3
-
14
-
-
34547123123
-
Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: A cohort analysis
-
Marty FM, Bryar J, Browne SK, et al. Sirolimus-based graft-versus-host disease prophylaxis protects against cytomegalovirus reactivation after allogeneic hematopoietic stem cell transplantation: a cohort analysis. Blood 2007;110:490-500.
-
(2007)
Blood
, vol.110
, pp. 490-500
-
-
Marty, F.M.1
Bryar, J.2
Browne, S.K.3
-
15
-
-
84862290097
-
Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients
-
Nashan B, Gaston R, Emery V, et al. Review of cytomegalovirus infection findings with mammalian target of rapamycin inhibitor-based immunosuppressive therapy in de novo renal transplant recipients. Transplantation 2012;93:1075-1085.
-
(2012)
Transplantation
, vol.93
, pp. 1075-1085
-
-
Nashan, B.1
Gaston, R.2
Emery, V.3
-
16
-
-
0037910271
-
Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis
-
Koenen HJ, Michielsen EC, Verstappen J, et al. Superior T-cell suppression by rapamycin and FK506 over rapamycin and cyclosporine A because of abrogated cytotoxic T-lymphocyte induction, impaired memory responses, and persistent apoptosis. Transplantation 2003;75:1581-1590.
-
(2003)
Transplantation
, vol.75
, pp. 1581-1590
-
-
Koenen, H.J.1
Michielsen, E.C.2
Verstappen, J.3
-
17
-
-
47249151462
-
Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation
-
Alyea EP, Li S, Kim HT, et al. Sirolimus, tacrolimus, and low-dose methotrexate as graft-versus-host disease prophylaxis in related and unrelated donor reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. Biol Blood Marrow Transplant 2008;14:920-926.
-
(2008)
Biol Blood Marrow Transplant
, vol.14
, pp. 920-926
-
-
Alyea, E.P.1
Li, S.2
Kim, H.T.3
-
18
-
-
66949177968
-
Comparison of tacrolimus and sirolimus (Tac/Sir) versus tacrolimus, sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation
-
Ho VT, Aldridge J, Kim HT, et al. Comparison of tacrolimus and sirolimus (Tac/Sir) versus tacrolimus, sirolimus, and mini-methotrexate (Tac/Sir/MTX) as acute graft-versus-host disease prophylaxis after reduced-intensity conditioning allogeneic peripheral blood stem cell transplantation. Biol Blood Marrow Transplant 2009;15:844-850.
-
(2009)
Biol Blood Marrow Transplant
, vol.15
, pp. 844-850
-
-
Ho, V.T.1
Aldridge, J.2
Kim, H.T.3
-
19
-
-
84863996947
-
Reduced intensity allogeneic hematopoietic stem cell transplantation for MDS using tacrolimus/sirolimus-based GVHD prophylaxis
-
Nakamura R, Palmer JM, O'Donnell MR, et al. Reduced intensity allogeneic hematopoietic stem cell transplantation for MDS using tacrolimus/sirolimus-based GVHD prophylaxis. Leuk Res 2012;36:1152-1156.
-
(2012)
Leuk Res
, vol.36
, pp. 1152-1156
-
-
Nakamura, R.1
Palmer, J.M.2
O'Donnell, M.R.3
-
20
-
-
0041941520
-
Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation
-
Antin JH, Kim HT, Cutler C, et al. Sirolimus, tacrolimus, and low-dose methotrexate for graft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation. Blood 2003;102:1601-1605.
-
(2003)
Blood
, vol.102
, pp. 1601-1605
-
-
Antin, J.H.1
Kim, H.T.2
Cutler, C.3
-
21
-
-
84896846970
-
A phase II study of a nonmyeloablative allogeneic stem cell transplant with peritransplant rituximab in patients with B cell lymphoid malignancies: Favorably durable event-free survival in chemosensitive patients
-
Sauter CS, Barker JN, Lechner L, et al. A phase II study of a nonmyeloablative allogeneic stem cell transplant with peritransplant rituximab in patients with B cell lymphoid malignancies: favorably durable event-free survival in chemosensitive patients. Biol Blood Marrow Transplant 2014;20:354-360.
-
(2014)
Biol Blood Marrow Transplant
, vol.20
, pp. 354-360
-
-
Sauter, C.S.1
Barker, J.N.2
Lechner, L.3
-
22
-
-
70350764819
-
Defining the intensity of conditioning regimens: Working definitions
-
Bacigalupo A, Ballen K, Rizzo D, et al. Defining the intensity of conditioning regimens: working definitions. Biol Blood Marrow Transplant 2009;15:1628-1633.
-
(2009)
Biol Blood Marrow Transplant
, vol.15
, pp. 1628-1633
-
-
Bacigalupo, A.1
Ballen, K.2
Rizzo, D.3
-
23
-
-
79959496711
-
Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies
-
Soiffer RJ, Lerademacher J, Ho V, et al. Impact of immune modulation with anti-T-cell antibodies on the outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation for hematologic malignancies. Blood 2011;117:6963-6970.
-
(2011)
Blood
, vol.117
, pp. 6963-6970
-
-
Soiffer, R.J.1
Lerademacher, J.2
Ho, V.3
-
24
-
-
58849161823
-
Single nucleotide polymorphism-based system improves the applicability of quantitative PCR for chimerism monitoring
-
Gineikiene E, Stoskus M, Griskevicius L. Single nucleotide polymorphism-based system improves the applicability of quantitative PCR for chimerism monitoring. J Mol Diagn 2009;11:66-74.
-
(2009)
J Mol Diagn
, vol.11
, pp. 66-74
-
-
Gineikiene, E.1
Stoskus, M.2
Griskevicius, L.3
-
25
-
-
8544247155
-
IBMTR Severity Index for grading acute graft-versus-host disease: Retrospective comparison with Glucksberg grade
-
Rowlings PA, Przepiorka D, Klein JP, et al. IBMTR Severity Index for grading acute graft-versus-host disease: retrospective comparison with Glucksberg grade. Br J Haematol 1997;97:855-864.
-
(1997)
Br J Haematol
, vol.97
, pp. 855-864
-
-
Rowlings, P.A.1
Przepiorka, D.2
Klein, J.P.3
-
26
-
-
28744444180
-
National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report
-
Filipovich AH, Weisdorf D, Pavletic S, et al. National Institutes of Health consensus development project on criteria for clinical trials in chronic graft-versus-host disease: I. Diagnosis and staging working group report. Biol Blood Marrow Transplant 2005;11:945-956.
-
(2005)
Biol Blood Marrow Transplant
, vol.11
, pp. 945-956
-
-
Filipovich, A.H.1
Weisdorf, D.2
Pavletic, S.3
-
27
-
-
0018973048
-
Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients
-
Shulman HM, Sullivan KM, Weiden PL, et al. Chronic graft-versus-host syndrome in man. A long-term clinicopathologic study of 20 Seattle patients. Am J Med 1980;69:204-217.
-
(1980)
Am J Med
, vol.69
, pp. 204-217
-
-
Shulman, H.M.1
Sullivan, K.M.2
Weiden, P.L.3
-
28
-
-
36048960178
-
A scheme for defining cause of death and its application in the T cell depletion trial
-
Copelan E, Casper JT, Carter SL, et al. A scheme for defining cause of death and its application in the T cell depletion trial. Biol Blood Marrow Transplant 2007;13:1469-1476.
-
(2007)
Biol Blood Marrow Transplant
, vol.13
, pp. 1469-1476
-
-
Copelan, E.1
Casper, J.T.2
Carter, S.L.3
-
29
-
-
0013886333
-
Evaluation of survival data and two new rank order statistics arising in its consideration
-
Mantel N. Evaluation of survival data and two new rank order statistics arising in its consideration. Cancer Chemother Rep 1966;50:163-170.
-
(1966)
Cancer Chemother Rep
, vol.50
, pp. 163-170
-
-
Mantel, N.1
-
30
-
-
0033566990
-
Risk factors for acute graft-versus-host disease after allogeneic blood stem cell transplantation
-
Przepiorka D, Smith TL, Folloder J, et al. Risk factors for acute graft-versus-host disease after allogeneic blood stem cell transplantation. Blood 1999;94:1465-1470.
-
(1999)
Blood
, vol.94
, pp. 1465-1470
-
-
Przepiorka, D.1
Smith, T.L.2
Folloder, J.3
-
31
-
-
0038189636
-
Higher doses of CD34 + peripheral blood stem cells are associated with increased mortality from chronic graft-versus-host disease after allogeneic HLA-identical sibling transplantation
-
Mohty M, Bilger K, Jourdan E, et al. Higher doses of CD34 + peripheral blood stem cells are associated with increased mortality from chronic graft-versus-host disease after allogeneic HLA-identical sibling transplantation. Leukemia 2003;17:869-875.
-
(2003)
Leukemia
, vol.17
, pp. 869-875
-
-
Mohty, M.1
Bilger, K.2
Jourdan, E.3
-
32
-
-
84873457670
-
A phase II study of sirolimus, tacrolimus and rabbit anti-thymocyte globulin as GVHD prophylaxis after unrelated-donor PBSC transplant
-
Khaled SK, Palmer J, Stiller T, et al. A phase II study of sirolimus, tacrolimus and rabbit anti-thymocyte globulin as GVHD prophylaxis after unrelated-donor PBSC transplant. Bone Marrow Transplant 2013;48:278-283.
-
(2013)
Bone Marrow Transplant
, vol.48
, pp. 278-283
-
-
Khaled, S.K.1
Palmer, J.2
Stiller, T.3
-
33
-
-
84919428945
-
A prospective study of an alemtuzumab containing reduced-intensity allogeneic stem cell transplant program in patients with poor-risk and advanced lymphoid malignancies
-
Mar 20. [Epub ahead of print]
-
Sauter CS, Chou JF, Papadopoulos EB, et al. A prospective study of an alemtuzumab containing reduced-intensity allogeneic stem cell transplant program in patients with poor-risk and advanced lymphoid malignancies. Leuk Lymphoma 2014 Mar 20. [Epub ahead of print]
-
(2014)
Leuk Lymphoma
-
-
Sauter, C.S.1
Chou, J.F.2
Papadopoulos, E.B.3
-
34
-
-
77649224551
-
A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens
-
Rodriguez R, Nakamura R, Palmer JM, et al. A phase II pilot study of tacrolimus/sirolimus GVHD prophylaxis for sibling donor hematopoietic stem cell transplantation using 3 conditioning regimens. Blood 2010;115:1098-1105.
-
(2010)
Blood
, vol.115
, pp. 1098-1105
-
-
Rodriguez, R.1
Nakamura, R.2
Palmer, J.M.3
-
35
-
-
41849148993
-
Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors
-
Furlong T, Kiem HP, Appelbaum FR, et al. Sirolimus in combination with cyclosporine or tacrolimus plus methotrexate for prevention of graft-versus-host disease following hematopoietic cell transplantation from unrelated donors. Biol Blood Marrow Transplant 2008;14:531-537.
-
(2008)
Biol Blood Marrow Transplant
, vol.14
, pp. 531-537
-
-
Furlong, T.1
Kiem, H.P.2
Appelbaum, F.R.3
-
36
-
-
58149388343
-
Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation
-
Cutler C, Stevenson K, Kim HT, et al. Sirolimus is associated with veno-occlusive disease of the liver after myeloablative allogeneic stem cell transplantation. Blood 2008;112:4425-4431.
-
(2008)
Blood
, vol.112
, pp. 4425-4431
-
-
Cutler, C.1
Stevenson, K.2
Kim, H.T.3
-
37
-
-
84872609549
-
Thrombotic microangiopathy associated with sirolimus level after allogeneic hematopoietic cell transplantation with tacrolimus/sirolimus-based graft-versus-host disease prophylaxis
-
Shayani S, Palmer J, Stiller T, et al. Thrombotic microangiopathy associated with sirolimus level after allogeneic hematopoietic cell transplantation with tacrolimus/sirolimus-based graft-versus-host disease prophylaxis. Biol Blood Marrow Transplant 2013;19:298-304.
-
(2013)
Biol Blood Marrow Transplant
, vol.19
, pp. 298-304
-
-
Shayani, S.1
Palmer, J.2
Stiller, T.3
-
38
-
-
84889559995
-
Tacrolimus/sirolimus vs. Tacrolimus/methotrexate for graft-vs.-host disease prophylaxis after HLA-matched, related donor hematopoietic stem cell transplantation: Results of Blood and Marrow Transplant Clinical Trials Network Trial 0402
-
Cutler C, Logan BR, Nakamura R, et al. Tacrolimus/sirolimus vs. tacrolimus/methotrexate for graft-vs.-host disease prophylaxis after HLA-matched, related donor hematopoietic stem cell transplantation: results of Blood and Marrow Transplant Clinical Trials Network Trial 0402. Blood 2012;120(Suppl. 1) Abstract 739.
-
(2012)
Blood
, vol.120
-
-
Cutler, C.1
Logan, B.R.2
Nakamura, R.3
-
39
-
-
84859631575
-
Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: A systematic review
-
Kumar A, Mhaskar AR, Reljic T, et al. Antithymocyte globulin for acute-graft-versus-host-disease prophylaxis in patients undergoing allogeneic hematopoietic cell transplantation: a systematic review. Leukemia 2012;26:582-588.
-
(2012)
Leukemia
, vol.26
, pp. 582-588
-
-
Kumar, A.1
Mhaskar, A.R.2
Reljic, T.3
-
40
-
-
73949093279
-
The role of B cells in the pathogenesis of graft-versus-host disease
-
Shimabukuro-Vornhagen A, Hallek MJ, Storb RF, et al. The role of B cells in the pathogenesis of graft-versus-host disease. Blood 2009;114:4919-4927.
-
(2009)
Blood
, vol.114
, pp. 4919-4927
-
-
Shimabukuro-Vornhagen, A.1
Hallek, M.J.2
Storb, R.F.3
-
41
-
-
84862744899
-
Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence
-
Arai S, Sahaf B, Narasimhan B, et al. Prophylactic rituximab after allogeneic transplantation decreases B-cell alloimmunity with low chronic GVHD incidence. Blood 2012;119:6145-6154.
-
(2012)
Blood
, vol.119
, pp. 6145-6154
-
-
Arai, S.1
Sahaf, B.2
Narasimhan, B.3
-
42
-
-
84901615992
-
Rituximab after lymphoma-directed conditioning and allogeneic stem-cell transplantation for relapsed and refractory aggressive non-Hodgkin lymphoma (DSHNHL R3): An open-label, randomised, phase 2 trial
-
Glass B, Hasenkamp J, Wulf G, et al. Rituximab after lymphoma-directed conditioning and allogeneic stem-cell transplantation for relapsed and refractory aggressive non-Hodgkin lymphoma (DSHNHL R3): an open-label, randomised, phase 2 trial. Lancet Oncol 2014;15:757-766.
-
(2014)
Lancet Oncol
, vol.15
, pp. 757-766
-
-
Glass, B.1
Hasenkamp, J.2
Wulf, G.3
-
43
-
-
57449092086
-
Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning
-
Armand P, Gannamaneni S, Kim HT, et al. Improved survival in lymphoma patients receiving sirolimus for graft-versus-host disease prophylaxis after allogeneic hematopoietic stem-cell transplantation with reduced-intensity conditioning. J Clin Oncol 2008;26:5767-5774.
-
(2008)
J Clin Oncol
, vol.26
, pp. 5767-5774
-
-
Armand, P.1
Gannamaneni, S.2
Kim, H.T.3
|