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Volumn 102, Issue 5, 2003, Pages 1601-1605

Sirolimus, tacrolimus, and low-dose methotrexate for gaft-versus-host disease prophylaxis in mismatched related donor or unrelated donor transplantation

Author keywords

[No Author keywords available]

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; RAPAMYCIN; TACROLIMUS;

EID: 0041941520     PISSN: 00064971     EISSN: None     Source Type: Journal    
DOI: 10.1182/blood-2003-02-0489     Document Type: Article
Times cited : (147)

References (41)
  • 1
    • 0345161813 scopus 로고    scopus 로고
    • Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with cyclosporine
    • Sirolimus European Renal Transplant Study Group
    • Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation. 1999;67:1036-1042.
    • (1999) Transplantation , vol.67 , pp. 1036-1042
    • Groth, C.G.1    Backman, L.2    Morales, J.M.3
  • 2
    • 33746530366 scopus 로고    scopus 로고
    • Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: A randomised multicentre study
    • The Rapamune US Study Group
    • Kahan BD. Efficacy of sirolimus compared with azathioprine for reduction of acute renal allograft rejection: a randomised multicentre study. The Rapamune US Study Group. Lancet. 2000;356:194-202.
    • (2000) Lancet , vol.356 , pp. 194-202
    • Kahan, B.D.1
  • 3
    • 0034721255 scopus 로고    scopus 로고
    • Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen
    • Shapiro AM, Lakey JR, Ryan EA, et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000;343:230-238.
    • (2000) N Engl J Med , vol.343 , pp. 230-238
    • Shapiro, A.M.1    Lakey, J.R.2    Ryan, E.A.3
  • 5
    • 0029872662 scopus 로고    scopus 로고
    • In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A
    • Blazar BR, Taylor PA, Panoskaltsis-Mortari A, Sehgal S, Vallera DA. In vivo inhibition of cytokine responsiveness and graft-versus-host disease mortality by rapamycin leads to a clinical-pathological syndrome discrete from that observed with cyclosporin A. Blood. 1996;87:4001-4009.
    • (1996) Blood , vol.87 , pp. 4001-4009
    • Blazar, B.R.1    Taylor, P.A.2    Panoskaltsis-Mortari, A.3    Sehgal, S.4    Vallera, D.A.5
  • 6
    • 0030984020 scopus 로고    scopus 로고
    • + T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients
    • + T cells each can utilize a perforin-dependent pathway to mediate lethal graft-versus-host disease in major histocompatibility complex-disparate recipients. Transplantation. 1997;64:571-576.
    • (1997) Transplantation , vol.64 , pp. 571-576
    • Blazar, B.R.1    Taylor, P.A.2    Vallera, D.A.3
  • 7
    • 0035660613 scopus 로고    scopus 로고
    • Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease
    • Benito AI, Furlong T, Martin PJ, et al. Sirolimus (rapamycin) for the treatment of steroid-refractory acute graft-versus-host disease. Transplantation. 2001;72:1924-1929.
    • (2001) Transplantation , vol.72 , pp. 1924-1929
    • Benito, A.I.1    Furlong, T.2    Martin, P.J.3
  • 8
    • 0030894459 scopus 로고    scopus 로고
    • Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection
    • Stepkowski SM, Tian L, Napoli KL, et al. Synergistic mechanisms by which sirolimus and cyclosporin inhibit rat heart and kidney allograft rejection. Clin Exp Immunol. 1997;108:63-68.
    • (1997) Clin Exp Immunol , vol.108 , pp. 63-68
    • Stepkowski, S.M.1    Tian, L.2    Napoli, K.L.3
  • 9
    • 0031700919 scopus 로고    scopus 로고
    • Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse
    • Chen H, Qi S, Xu D, et al. Combined effect of rapamycin and FK 506 in prolongation of small bowel graft survival in the mouse. Transplant Proc. 1998;30:2579-2581.
    • (1998) Transplant Proc , vol.30 , pp. 2579-2581
    • Chen, H.1    Qi, S.2    Xu, D.3
  • 10
    • 0033428489 scopus 로고    scopus 로고
    • Synergistic effect of rapamycin and cyclosporine in prevention of acute kidney allograft rejection in the mouse
    • Qi S, Xu D, Peng J, Liu D, Chen H. Synergistic effect of rapamycin and cyclosporine in prevention of acute kidney allograft rejection in the mouse. Microsurgery. 1999;19:344-347.
    • (1999) Microsurgery , vol.19 , pp. 344-347
    • Qi, S.1    Xu, D.2    Peng, J.3    Liu, D.4    Chen, H.5
  • 11
    • 18244423842 scopus 로고    scopus 로고
    • Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey
    • Qi S, Xu D, Peng J, et al. Effect of tacrolimus (FK506) and sirolimus (rapamycin) mono- and combination therapy in prolongation of renal allograft survival in the monkey. Transplantation. 2000;69:1275-1283.
    • (2000) Transplantation , vol.69 , pp. 1275-1283
    • Qi, S.1    Xu, D.2    Peng, J.3
  • 12
    • 0031113473 scopus 로고    scopus 로고
    • The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host disease prophylaxis
    • Devine SM, Geller RB, Lin LB, et al. The outcome of unrelated donor bone marrow transplantation in patients with hematologic malignancies using tacrolimus (FK506) and low dose methotrexate for graft-versus-host disease prophylaxis. Biol Blood Marrow Transplant. 1997;3:25-33.
    • (1997) Biol Blood Marrow Transplant , vol.3 , pp. 25-33
    • Devine, S.M.1    Geller, R.B.2    Lin, L.B.3
  • 13
    • 0032884873 scopus 로고    scopus 로고
    • Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease aiter HLA-mismatched marrow or blood stem cell transplantation
    • Przepiorka D, Khouri I, Ippoliti C, et al. Tacrolimus and minidose methotrexate for prevention of acute graft-versus-host disease aiter HLA-mismatched marrow or blood stem cell transplantation. Bone Marrow Transplant. 1999;24:763-768.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 763-768
    • Przepiorka, D.1    Khouri, I.2    Ippoliti, C.3
  • 14
    • 0034665674 scopus 로고    scopus 로고
    • A phase III study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors
    • Nash R, Antin J, Karanes C, et al. A phase III study comparing methotrexate and tacrolimus with methotrexate and cyclosporine for prophylaxis of acute graft-versus-host disease after marrow transplantation from unrelated donors. Blood. 2000;96:2062-2068.
    • (2000) Blood , vol.96 , pp. 2062-2068
    • Nash, R.1    Antin, J.2    Karanes, C.3
  • 15
    • 0008947293 scopus 로고    scopus 로고
    • Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia
    • Hansen JA, Gooley TA, Martin PJ, et al. Bone marrow transplants from unrelated donors for patients with chronic myeloid leukemia. N Engl J Med. 1998;338:962-968.
    • (1998) N Engl J Med , vol.338 , pp. 962-968
    • Hansen, J.A.1    Gooley, T.A.2    Martin, P.J.3
  • 17
    • 0000120995 scopus 로고
    • A class of K-sample tests for comparing the cumulative incidence of a competing risk
    • Gray R. A class of K-sample tests for comparing the cumulative incidence of a competing risk. Annals of Statistics. 1988;16:1141-1154.
    • (1988) Annals of Statistics , vol.16 , pp. 1141-1154
    • Gray, R.1
  • 18
    • 0032188990 scopus 로고    scopus 로고
    • Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation
    • Ratanatharathorn V, Nash RA, Przepiorka D, et al. Phase III study comparing methotrexate and tacrolimus (prograf, FK506) with methotrexate and cyclosporine for graft-versus-host disease prophylaxis after HLA-identical sibling bone marrow transplantation. Blood. 1998;92:2303-2314.
    • (1998) Blood , vol.92 , pp. 2303-2314
    • Ratanatharathorn, V.1    Nash, R.A.2    Przepiorka, D.3
  • 19
    • 0037085807 scopus 로고    scopus 로고
    • Allogeneic bone marrow transplantation for chronic myelogenous leukemia: Comparative analysis of unrelated versus matched sibling donor transplantation
    • Weisdorf DJ, Anasetti C, Antin JH, et al. Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation. Blood. 2002;99:1971-1977.
    • (2002) Blood , vol.99 , pp. 1971-1977
    • Weisdorf, D.J.1    Anasetti, C.2    Antin, J.H.3
  • 20
    • 12944309759 scopus 로고    scopus 로고
    • Unrelated donor marrow transplantation for chronic myelogenous leukemia: 9 Years' experience of the national marrow donor program
    • McGlave PB, Shu XO, Wen W, et al. Unrelated donor marrow transplantation for chronic myelogenous leukemia: 9 years' experience of the national marrow donor program. Blood. 2000;95:2219-2225.
    • (2000) Blood , vol.95 , pp. 2219-2225
    • McGlave, P.B.1    Shu, X.O.2    Wen, W.3
  • 21
    • 0035496909 scopus 로고    scopus 로고
    • Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: The effect of donor age
    • Kollman C, Howe CW, Anasetti C, et al. Donor characteristics as risk factors in recipients after transplantation of bone marrow from unrelated donors: the effect of donor age. Blood. 2001;98:2043-2051.
    • (2001) Blood , vol.98 , pp. 2043-2051
    • Kollman, C.1    Howe, C.W.2    Anasetti, C.3
  • 22
    • 0031951281 scopus 로고    scopus 로고
    • Effect of HLA matching on outcome of related and unrelated donor transplantation therapy for chronic myelogenous leukemia
    • Petersdorf E, Anasetti C, Servida P, Martin P, Hansen J. Effect of HLA matching on outcome of related and unrelated donor transplantation therapy for chronic myelogenous leukemia. Hematol Oncol Clin North Am. 1998;12:107-121.
    • (1998) Hematol Oncol Clin North Am , vol.12 , pp. 107-121
    • Petersdorf, E.1    Anasetti, C.2    Servida, P.3    Martin, P.4    Hansen, J.5
  • 23
    • 0035892132 scopus 로고    scopus 로고
    • Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: The US National Marrow Donor Program Experience
    • Petersdorf EW, Kollman C, Hurley CK, et al. Effect of HLA class II gene disparity on clinical outcome in unrelated donor hematopoietic cell transplantation for chronic myeloid leukemia: the US National Marrow Donor Program Experience. Blood. 2001;98:2922-2929,
    • (2001) Blood , vol.98 , pp. 2922-2929
    • Petersdorf, E.W.1    Kollman, C.2    Hurley, C.K.3
  • 24
    • 0037085746 scopus 로고    scopus 로고
    • Unrelated donor marrow transplantation for myelodysplastic syndromes: Outcome analysis in 510 transplants facilitated by the National Marrow Donor Program
    • Castro-Malaspina H, Harris RE, Gajewski J, et al. Unrelated donor marrow transplantation for myelodysplastic syndromes: outcome analysis in 510 transplants facilitated by the National Marrow Donor Program. Blood. 2002;99:1943-1951.
    • (2002) Blood , vol.99 , pp. 1943-1951
    • Castro-Malaspina, H.1    Harris, R.E.2    Gajewski, J.3
  • 25
    • 0032105481 scopus 로고    scopus 로고
    • Rapamune (RAPA), rapamycin, sirolimus: Mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression
    • Sehgal S. Rapamune (RAPA), rapamycin, sirolimus: mechanism of action immunosuppressive effect results from blockade of signal transduction and inhibition of cell cycle progression. Clin Biochem. 1998;31:335-340.
    • (1998) Clin Biochem , vol.31 , pp. 335-340
    • Sehgal, S.1
  • 26
    • 0027970168 scopus 로고
    • CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin
    • Lai JH, Tan TH. CD28 signaling causes a sustained down-regulation of I kappa B alpha which can be prevented by the immunosuppressant rapamycin. J Biol Chem. 1994;269:30077-30080.
    • (1994) J Biol Chem , vol.269 , pp. 30077-30080
    • Lai, J.H.1    Tan, T.H.2
  • 27
    • 0345164351 scopus 로고    scopus 로고
    • Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment
    • Li Y, Zheng XX, Li XC, Zand MS, Strom TB. Combined costimulation blockade plus rapamycin but not cyclosporine produces permanent engraftment. Transplantation. 1998;66:1387-1388.
    • (1998) Transplantation , vol.66 , pp. 1387-1388
    • Li, Y.1    Zheng, X.X.2    Li, X.C.3    Zand, M.S.4    Strom, T.B.5
  • 28
    • 0344613988 scopus 로고    scopus 로고
    • Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance
    • Li Y, Li XC, Zheng XX, Wells AD, Turka LA, Strom TB. Blocking both signal 1 and signal 2 of T-cell activation prevents apoptosis of alloreactive T cells and induction of peripheral allograft tolerance. Nat Med. 1999;5:1298-1302.
    • (1999) Nat Med , vol.5 , pp. 1298-1302
    • Li, Y.1    Li, X.C.2    Zheng, X.X.3    Wells, A.D.4    Turka, L.A.5    Strom, T.B.6
  • 30
    • 0029054455 scopus 로고
    • Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation
    • Miyazaki T, Liu ZJ, Kawahara A, et al. Three distinct IL-2 signaling pathways mediated by bcl-2, c-myc, and lck cooperate in hematopoietic cell proliferation. Cell. 1995;81:223-231.
    • (1995) Cell , vol.81 , pp. 223-231
    • Miyazaki, T.1    Liu, Z.J.2    Kawahara, A.3
  • 31
    • 0033575383 scopus 로고    scopus 로고
    • Prevention of graft versus host disease by inactivation of host antigen-presenting cells
    • Shlomchik WD, Couzens MS, Tang CB, et al. Prevention of graft versus host disease by inactivation of host antigen-presenting cells. Science. 1999;285:412-415.
    • (1999) Science , vol.285 , pp. 412-415
    • Shlomchik, W.D.1    Couzens, M.S.2    Tang, C.B.3
  • 32
    • 0037114157 scopus 로고    scopus 로고
    • - T cells to elicit hepatic graft-versus-host disease
    • - T cells to elicit hepatic graft-versus-host disease. J Immunol. 2002;169:7111-7118.
    • (2002) J Immunol , vol.169 , pp. 7111-7118
    • Zhang, Y.1    Shlomchik, W.D.2    Joe, G.3
  • 34
    • 0038036797 scopus 로고    scopus 로고
    • Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo
    • Hackstein H, Taner T, Zahorchak AF, et al. Rapamycin inhibits IL-4-induced dendritic cell maturation in vitro and dendritic cell mobilization and function in vivo. Blood. 2003;101:4457-4463.
    • (2003) Blood , vol.101 , pp. 4457-4463
    • Hackstein, H.1    Taner, T.2    Zahorchak, A.F.3
  • 35
    • 0037441902 scopus 로고    scopus 로고
    • Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression
    • Woltman AM, Van Der Kooij SW, Coffer PJ, Offringa R, Daha MR, Van Kooten C. Rapamycin specifically interferes with GM-CSF signaling in human dendritic cells, leading to apoptosis via increased p27KIP1 expression. Blood. 2003;101:1439-1445.
    • (2003) Blood , vol.101 , pp. 1439-1445
    • Woltman, A.M.1    Van Der Kooij, S.W.2    Coffer, P.J.3    Offringa, R.4    Daha, M.R.5    Van Kooten, C.6
  • 36
    • 0036784638 scopus 로고    scopus 로고
    • Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T-cell interaction during antigen presentation
    • Matsue H, Yang C, Matsue K, Edelbaum D, Mummert M, Takashima A. Contrasting impacts of immunosuppressive agents (rapamycin, FK506, cyclosporin A, and dexamethasone) on bidirectional dendritic cell-T-cell interaction during antigen presentation. J Immunol. 2002;169:3555-3564.
    • (2002) J Immunol , vol.169 , pp. 3555-3564
    • Matsue, H.1    Yang, C.2    Matsue, K.3    Edelbaum, D.4    Mummert, M.5    Takashima, A.6
  • 37
    • 0030064388 scopus 로고    scopus 로고
    • The side effect profile of sirolimus: A phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients
    • Murgia MG, Jordan S, Kahan BD. The side effect profile of sirolimus: a phase I study in quiescent cyclosporine-prednisone-treated renal transplant patients. Kidney Int. 1996;49:209-216.
    • (1996) Kidney Int , vol.49 , pp. 209-216
    • Murgia, M.G.1    Jordan, S.2    Kahan, B.D.3
  • 38
    • 0345161813 scopus 로고    scopus 로고
    • Sirolimus (rapamycin)-based therapy in human renal transplantation: Similar efficacy and different toxicity compared with cyclosporine
    • Sirolimus European Renal Transplant Study Group
    • Groth CG, Backman L, Morales JM, et al. Sirolimus (rapamycin)-based therapy in human renal transplantation: similar efficacy and different toxicity compared with cyclosporine. Sirolimus European Renal Transplant Study Group. Transplantation. 1999;67:1036-1042.
    • (1999) Transplantation , vol.67 , pp. 1036-1042
    • Groth, C.G.1    Backman, L.2    Morales, J.M.3
  • 39
    • 0034786155 scopus 로고    scopus 로고
    • Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: A randomized controlled trial
    • Reitamo S, Spuls P, Sassolas B, Lahfa M, Claudy A, Griffiths CE. Efficacy of sirolimus (rapamycin) administered concomitantly with a subtherapeutic dose of cyclosporin in the treatment of severe psoriasis: a randomized controlled trial. Br J Dermatol. 2001;145:438-445.
    • (2001) Br J Dermatol , vol.145 , pp. 438-445
    • Reitamo, S.1    Spuls, P.2    Sassolas, B.3    Lahfa, M.4    Claudy, A.5    Griffiths, C.E.6
  • 40
    • 0037111657 scopus 로고    scopus 로고
    • Interleukin-1 blockade does not prevent acute graft-versus-host disease: Results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation
    • Antin JH, Weisdorf D, Neuberg D, et al. Interleukin-1 blockade does not prevent acute graft-versus-host disease: results of a randomized, double-blind, placebo-controlled trial of interleukin-1 receptor antagonist in allogeneic bone marrow transplantation. Blood. 2002;100:3479-3482.
    • (2002) Blood , vol.100 , pp. 3479-3482
    • Antin, J.H.1    Weisdorf, D.2    Neuberg, D.3
  • 41
    • 0037087662 scopus 로고    scopus 로고
    • De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine-sirolimus combination
    • Langer RM, Van Buren CT, Katz SM, Kahan BD. De novo hemolytic uremic syndrome after kidney transplantation in patients treated with cyclosporine-sirolimus combination. Transplantation. 2002;73:756-760.
    • (2002) Transplantation , vol.73 , pp. 756-760
    • Langer, R.M.1    Van Buren, C.T.2    Katz, S.M.3    Kahan, B.D.4


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