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Volumn 30, Issue 3, 2015, Pages 393-401

A longitudinal study of magnetic resonance spectroscopy Huntington's disease biomarkers

Author keywords

Huntington's disease; MRI; MRS; Myo inositol (MI); N acetyl aspartate (NAA)

Indexed keywords

BIOLOGICAL MARKER; INOSITOL; N ACETYLASPARTIC ACID; ASPARTIC ACID; N-ACETYLASPARTATE;

EID: 84924598441     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.26118     Document Type: Article
Times cited : (46)

References (40)
  • 1
    • 0027480960 scopus 로고
    • A novel gene. containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes
    • Huntington's Disease Collaborative Research Group. A novel gene. containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. Cell 1993;72:971-983.
    • (1993) Cell , vol.72 , pp. 971-983
  • 2
    • 68249113963 scopus 로고    scopus 로고
    • Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data
    • Tabrizi SJ, Langbehn DR, Leavitt BR, et al. Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data. Lancet Neurol 2009;8:791-801.
    • (2009) Lancet Neurol , vol.8 , pp. 791-801
    • Tabrizi, S.J.1    Langbehn, D.R.2    Leavitt, B.R.3
  • 3
    • 78650026297 scopus 로고    scopus 로고
    • Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis
    • Tabrizi SJ, Scahill RI, Durr A, et al. Biological and clinical changes in premanifest and early stage Huntington's disease in the TRACK-HD study: the 12-month longitudinal analysis. Lancet Neurol 2011;10:31-42.
    • (2011) Lancet Neurol , vol.10 , pp. 31-42
    • Tabrizi, S.J.1    Scahill, R.I.2    Durr, A.3
  • 4
    • 48249114740 scopus 로고    scopus 로고
    • Detection of Huntington's disease decades before diagnosis: the Predict-HD study
    • Paulsen JS, Langbehn DR, Stout JC, et al. Detection of Huntington's disease decades before diagnosis: the Predict-HD study. J Neurol Neurosurg Psychiatry 2008;79:874-880.
    • (2008) J Neurol Neurosurg Psychiatry , vol.79 , pp. 874-880
    • Paulsen, J.S.1    Langbehn, D.R.2    Stout, J.C.3
  • 5
    • 78650005406 scopus 로고    scopus 로고
    • Magnetic resonance spectroscopy biomarkers in premanifest and early Huntington disease
    • Sturrock A, Laule C, Decolongon J, et al. Magnetic resonance spectroscopy biomarkers in premanifest and early Huntington disease. Neurology 2010;75:1702-1710.
    • (2010) Neurology , vol.75 , pp. 1702-1710
    • Sturrock, A.1    Laule, C.2    Decolongon, J.3
  • 6
    • 0031035154 scopus 로고    scopus 로고
    • Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study
    • Harms L, Meierkord H, Timm G, Pfeiffer L, Ludolph AC. Decreased N-acetyl-aspartate/choline ratio and increased lactate in the frontal lobe of patients with Huntington's disease: a proton magnetic resonance spectroscopy study. J Neurol Neurosurg Psychiatry 1997;62:27-30.
    • (1997) J Neurol Neurosurg Psychiatry , vol.62 , pp. 27-30
    • Harms, L.1    Meierkord, H.2    Timm, G.3    Pfeiffer, L.4    Ludolph, A.C.5
  • 7
    • 0031900412 scopus 로고    scopus 로고
    • Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases
    • Hoang TQ, Bluml S, Dubowitz DJ, et al. Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology 1998;50:1033-1040.
    • (1998) Neurology , vol.50 , pp. 1033-1040
    • Hoang, T.Q.1    Bluml, S.2    Dubowitz, D.J.3
  • 8
    • 0031596998 scopus 로고    scopus 로고
    • 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers
    • Jenkins BG, Rosas HD, Chen YC, et al. 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers. Neurology 1998;50:1357-1365.
    • (1998) Neurology , vol.50 , pp. 1357-1365
    • Jenkins, B.G.1    Rosas, H.D.2    Chen, Y.C.3
  • 10
    • 11144291556 scopus 로고    scopus 로고
    • Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease
    • Reynolds NC Jr, Prost RW, Mark LP. Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease. Brain Res 2005;1031:82-89.
    • (2005) Brain Res , vol.1031 , pp. 82-89
    • Reynolds Jr, N.C.1    Prost, R.W.2    Mark, L.P.3
  • 11
    • 34247126402 scopus 로고    scopus 로고
    • Decreased frontal choline and neuropsychological performance in preclinical Huntington disease
    • Gómez-Ansón B, Alegret M, Muñoz E, Sainz A, Monte GC, Tolosa E. Decreased frontal choline and neuropsychological performance in preclinical Huntington disease. Neurology 2007;68:906-910.
    • (2007) Neurology , vol.68 , pp. 906-910
    • Gómez-Ansón, B.1    Alegret, M.2    Muñoz, E.3    Sainz, A.4    Monte, G.C.5    Tolosa, E.6
  • 12
    • 34548275049 scopus 로고    scopus 로고
    • 1H magnetic resonance spectroscopy in preclinical Huntington disease
    • van Oostrom JC, Sijens PE, Roos RA, Leenders KL. 1H magnetic resonance spectroscopy in preclinical Huntington disease. Brain Res 2007;1168:67-71.
    • (2007) Brain Res , vol.1168 , pp. 67-71
    • van Oostrom, J.C.1    Sijens, P.E.2    Roos, R.A.3    Leenders, K.L.4
  • 13
    • 37549042776 scopus 로고    scopus 로고
    • Evidence of thalamic dysfunction in Huntington disease by proton magnetic resonance spectroscopy
    • Ruocco HH, Lopes-Cendes I, Li LM, Cendes F. Evidence of thalamic dysfunction in Huntington disease by proton magnetic resonance spectroscopy. Mov Disord 2007;22:2052-2056.
    • (2007) Mov Disord , vol.22 , pp. 2052-2056
    • Ruocco, H.H.1    Lopes-Cendes, I.2    Li, L.M.3    Cendes, F.4
  • 14
    • 0018303366 scopus 로고
    • Huntington disease: clinical care and evaluation
    • Shoulson I, Fahn S. Huntington disease: clinical care and evaluation. Neurology 1979;29:1-3.
    • (1979) Neurology , vol.29 , pp. 1-3
    • Shoulson, I.1    Fahn, S.2
  • 16
    • 0027375098 scopus 로고
    • Estimation of metabolite concentrations from localized in vivo proton NMR spectra
    • Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-679.
    • (1993) Magn Reson Med , vol.30 , pp. 672-679
    • Provencher, S.W.1
  • 17
    • 84924622200 scopus 로고    scopus 로고
    • LCModel and LCMGui User's Manual.
    • Provencher S, LCModel and LCMGui User's Manual, 2005. Available at: http://S-provencher.com.
    • (2005)
    • Provencher, S.1
  • 19
    • 0033437155 scopus 로고    scopus 로고
    • Riluzole therapy in Huntington's disease (HD)
    • Rosas HD, Koroshetz WJ, Jenkins BG, et al. Riluzole therapy in Huntington's disease (HD). Mov Disord 1999;14:326-330.
    • (1999) Mov Disord , vol.14 , pp. 326-330
    • Rosas, H.D.1    Koroshetz, W.J.2    Jenkins, B.G.3
  • 20
    • 0037677341 scopus 로고    scopus 로고
    • Creatine therapy for Huntington's disease: clinical and MRS findings in a 1-year pilot study
    • Tabrizi SJ, Blamire AM, Manners DN, et al. Creatine therapy for Huntington's disease: clinical and MRS findings in a 1-year pilot study. Neurology 2003;61:141-142.
    • (2003) Neurology , vol.61 , pp. 141-142
    • Tabrizi, S.J.1    Blamire, A.M.2    Manners, D.N.3
  • 21
    • 18144370445 scopus 로고    scopus 로고
    • High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study
    • Tabrizi SJ, Blamire AM, Manners DN, et al. High-dose creatine therapy for Huntington disease: a 2-year clinical and MRS study. Neurology 2005;64:1655-1656.
    • (2005) Neurology , vol.64 , pp. 1655-1656
    • Tabrizi, S.J.1    Blamire, A.M.2    Manners, D.N.3
  • 22
    • 19944431628 scopus 로고    scopus 로고
    • Creatine supplementation lowers brain glutamate levels in Huntington's disease
    • Bender A, Auer DP, Merl T, et al. Creatine supplementation lowers brain glutamate levels in Huntington's disease. J Neurol 2005;252:36-41.
    • (2005) J Neurol , vol.252 , pp. 36-41
    • Bender, A.1    Auer, D.P.2    Merl, T.3
  • 24
    • 0029943742 scopus 로고    scopus 로고
    • Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory
    • Taylor-Robinson SD, Weeks RA, Bryant DJ, et al. Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory. Mov Disord 1996;11:167-173.
    • (1996) Mov Disord , vol.11 , pp. 167-173
    • Taylor-Robinson, S.D.1    Weeks, R.A.2    Bryant, D.J.3
  • 25
    • 0028244281 scopus 로고
    • Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease
    • Moats RA, Ernst T, Shonk TK, Ross BD. Abnormal cerebral metabolite concentrations in patients with probable Alzheimer disease. Magn Reson Med 1994;32:110-115.
    • (1994) Magn Reson Med , vol.32 , pp. 110-115
    • Moats, R.A.1    Ernst, T.2    Shonk, T.K.3    Ross, B.D.4
  • 26
    • 0032102114 scopus 로고    scopus 로고
    • Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy
    • Kalra S, Cashman NR, Genge A, Arnold DL. Recovery of N-acetylaspartate in corticomotor neurons of patients with ALS after riluzole therapy. Neuroreport 1998;9:1757-1761.
    • (1998) Neuroreport , vol.9 , pp. 1757-1761
    • Kalra, S.1    Cashman, N.R.2    Genge, A.3    Arnold, D.L.4
  • 28
    • 0034006477 scopus 로고    scopus 로고
    • Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice
    • Jenkins BG, Klivenyi P, Kustermann E, et al. Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice. J Neurochem 2000;74:2108-2119.
    • (2000) J Neurochem , vol.74 , pp. 2108-2119
    • Jenkins, B.G.1    Klivenyi, P.2    Kustermann, E.3
  • 29
    • 0018622817 scopus 로고
    • Synthesis of N-acetyl-L-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport
    • Patel TB, Clark JB. Synthesis of N-acetyl-L-aspartate by rat brain mitochondria and its involvement in mitochondrial/cytosolic carbon transport. Biochem J 1979;184:539-546.
    • (1979) Biochem J , vol.184 , pp. 539-546
    • Patel, T.B.1    Clark, J.B.2
  • 30
    • 0028792005 scopus 로고
    • Reversible decreases in N-acetylaspartate after acute brain injury
    • De Stefano N, Matthews PM, Arnold DL. Reversible decreases in N-acetylaspartate after acute brain injury. Magn Reson Med 1995;34:721-727.
    • (1995) Magn Reson Med , vol.34 , pp. 721-727
    • De Stefano, N.1    Matthews, P.M.2    Arnold, D.L.3
  • 31
    • 0034743672 scopus 로고    scopus 로고
    • Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease
    • Andreassen OA, Dedeoglu A, Ferrante RJ, et al. Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease. Neurobiol Dis 2001;8:479-491.
    • (2001) Neurobiol Dis , vol.8 , pp. 479-491
    • Andreassen, O.A.1    Dedeoglu, A.2    Ferrante, R.J.3
  • 32
    • 0034660457 scopus 로고    scopus 로고
    • Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease
    • Ferrante RJ, Andreassen OA, Jenkins BG, et al. Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease. J Neurosci 2000;20:4389-4397.
    • (2000) J Neurosci , vol.20 , pp. 4389-4397
    • Ferrante, R.J.1    Andreassen, O.A.2    Jenkins, B.G.3
  • 33
    • 1942424261 scopus 로고    scopus 로고
    • Magnetic resonance imaging and spectroscopy in assessing 3-nitropropionic acid-induced brain lesions: an animal model of Huntington's disease
    • Lee WT, Chang, C. Magnetic resonance imaging and spectroscopy in assessing 3-nitropropionic acid-induced brain lesions: an animal model of Huntington's disease. Prog Neurobiol 2004;72:87-110.
    • (2004) Prog Neurobiol , vol.72 , pp. 87-110
    • Lee, W.T.1    Chang, C.2
  • 34
    • 77149126405 scopus 로고    scopus 로고
    • Longitudinal MRI and MRSI characterization of the quinolinic acid rat model for excitotoxicity: peculiar apparent diffusion coefficients and recovery of N-acetyl aspartate levels
    • Shemesh N, Sadan O, Melamed E, Offen D, Cohen Y. Longitudinal MRI and MRSI characterization of the quinolinic acid rat model for excitotoxicity: peculiar apparent diffusion coefficients and recovery of N-acetyl aspartate levels. NMR Biomed 2010;23:196-206.
    • (2010) NMR Biomed , vol.23 , pp. 196-206
    • Shemesh, N.1    Sadan, O.2    Melamed, E.3    Offen, D.4    Cohen, Y.5
  • 36
    • 33846970909 scopus 로고    scopus 로고
    • Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy
    • Tkac I, Dubinsky JM, Keene CD, Gruetter R, Low WC. Neurochemical changes in Huntington R6/2 mouse striatum detected by in vivo 1H NMR spectroscopy. J Neurochem 2007;100:1397-1406.
    • (2007) J Neurochem , vol.100 , pp. 1397-1406
    • Tkac, I.1    Dubinsky, J.M.2    Keene, C.D.3    Gruetter, R.4    Low, W.C.5
  • 37
    • 84896141552 scopus 로고    scopus 로고
    • Neurochemical correlates of caudate atrophy in Huntington's disease
    • Padowski JM, Weaver KE, Richards TL, et al. Neurochemical correlates of caudate atrophy in Huntington's disease. Mov Disord 2014;29:327-335.
    • (2014) Mov Disord , vol.29 , pp. 327-335
    • Padowski, J.M.1    Weaver, K.E.2    Richards, T.L.3
  • 38
    • 0033859547 scopus 로고    scopus 로고
    • Metabolic and cognitive. response to human traumatic brain injury: a quantitative proton magnetic.resonance study
    • Brooks WM, Stidley CA, Petropoulos H, et al. Metabolic and cognitive. response to human traumatic brain injury: a quantitative proton magnetic.resonance study. J Neurotrauma 2000;17:629-640.
    • (2000) J Neurotrauma , vol.17 , pp. 629-640
    • Brooks, W.M.1    Stidley, C.A.2    Petropoulos, H.3
  • 39
    • 84880276763 scopus 로고    scopus 로고
    • Neuroprotection with glatiramer acetate: evidence from the PreCISe trial
    • Arnold DL, Narayanan S, Antel S. Neuroprotection with glatiramer acetate: evidence from the PreCISe trial. J Neurol 2013;260:1901-1906.
    • (2013) J Neurol , vol.260 , pp. 1901-1906
    • Arnold, D.L.1    Narayanan, S.2    Antel, S.3
  • 40
    • 84888035253 scopus 로고    scopus 로고
    • Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update
    • Bustillo JR. Use of proton magnetic resonance spectroscopy in the treatment of psychiatric disorders: a critical update. Dialogues Clin Neurosci 2013;15:329-337.
    • (2013) Dialogues Clin Neurosci , vol.15 , pp. 329-337
    • Bustillo, J.R.1


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