-
1
-
-
0027480960
-
[No authors listed] A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group
-
[No authors listed] A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes. The Huntington's Disease Collaborative Research Group. Cell 1993;72:971-983.
-
(1993)
Cell
, vol.72
, pp. 971-983
-
-
-
2
-
-
33646085784
-
The association of CAG repeat length with clinical progression in Huntington disease
-
Rosenblatt A, Liang KY, Zhou H, et al. The association of CAG repeat length with clinical progression in Huntington disease. Neurology 2006;66:1016-1020.
-
(2006)
Neurology
, vol.66
, pp. 1016-1020
-
-
Rosenblatt, A.1
Liang, K.Y.2
Zhou, H.3
-
3
-
-
79952740327
-
Longitudinal change in regional brain volumes in prodromal Huntington disease
-
Aylward EH, Nopoulos PC, Ross CA, et al. Longitudinal change in regional brain volumes in prodromal Huntington disease. J Neurol Neurosurg Psychiatry 2011;82:405-410.
-
(2011)
J Neurol Neurosurg Psychiatry
, vol.82
, pp. 405-410
-
-
Aylward, E.H.1
Nopoulos, P.C.2
Ross, C.A.3
-
4
-
-
84860482627
-
The search for sensitive biomarkers in presymptomatic Huntington disease
-
Henry PG, Mochel F. The search for sensitive biomarkers in presymptomatic Huntington disease. J Cereb Blood Flow Metab 2012;32:769-770.
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, pp. 769-770
-
-
Henry, P.G.1
Mochel, F.2
-
5
-
-
33847607138
-
Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease
-
Aylward EH. Change in MRI striatal volumes as a biomarker in preclinical Huntington's disease. Brain Res Bull 2007;72(2-3):152-158.
-
(2007)
Brain Res Bull
, vol.72
, Issue.2-3
, pp. 152-158
-
-
Aylward, E.H.1
-
6
-
-
0034006477
-
Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice
-
Jenkins BG, Klivenyi P, Kustermann E, et al. Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice. J Neurochem 2000;74:2108-2119.
-
(2000)
J Neurochem
, vol.74
, pp. 2108-2119
-
-
Jenkins, B.G.1
Klivenyi, P.2
Kustermann, E.3
-
7
-
-
78650005406
-
Magnetic resonance spectroscopy biomarkers in premanifest and early Huntington disease
-
Sturrock A, Laule C, Decolongon J, et al. Magnetic resonance spectroscopy biomarkers in premanifest and early Huntington disease. Neurology 2010;75:1702-1710.
-
(2010)
Neurology
, vol.75
, pp. 1702-1710
-
-
Sturrock, A.1
Laule, C.2
Decolongon, J.3
-
8
-
-
34247126402
-
Decreased frontal choline and neuropsychological performance in preclinical Huntington disease
-
Gomez-Anson B, Alegret M, Munoz E, Sainz A, Monte GC, Tolosa E. Decreased frontal choline and neuropsychological performance in preclinical Huntington disease. Neurology 2007;68:906-910.
-
(2007)
Neurology
, vol.68
, pp. 906-910
-
-
Gomez-Anson, B.1
Alegret, M.2
Munoz, E.3
Sainz, A.4
Monte, G.C.5
Tolosa, E.6
-
9
-
-
0033546998
-
Clinical correlation of striatal 1H MRS changes in Huntington's disease
-
Sanchez-Pernaute R, Garcia-Segura JM, del Barrio Alba A, Viano J, de Yebenes JG. Clinical correlation of striatal 1H MRS changes in Huntington's disease. Neurology 1999;53:806-812.
-
(1999)
Neurology
, vol.53
, pp. 806-812
-
-
Sanchez-Pernaute, R.1
Garcia-Segura, J.M.2
del Barrio Alba, A.3
Viano, J.4
de Yebenes, J.G.5
-
10
-
-
0029943742
-
Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory
-
Taylor-Robinson SD, Weeks RA, Bryant DJ, et al. Proton magnetic resonance spectroscopy in Huntington's disease: evidence in favour of the glutamate excitotoxic theory. Mov Disord 1996;11:167-173.
-
(1996)
Mov Disord
, vol.11
, pp. 167-173
-
-
Taylor-Robinson, S.D.1
Weeks, R.A.2
Bryant, D.J.3
-
11
-
-
83255186677
-
Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington's disease provides in vivo evidence for impaired energy metabolism
-
van den Bogaard SJ, Dumas EM, Teeuwisse WM, et al. Exploratory 7-Tesla magnetic resonance spectroscopy in Huntington's disease provides in vivo evidence for impaired energy metabolism. J Neurol 2011;258:2230-2239.
-
(2011)
J Neurol
, vol.258
, pp. 2230-2239
-
-
van den Bogaard, S.J.1
Dumas, E.M.2
Teeuwisse, W.M.3
-
12
-
-
0031900412
-
Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases
-
Hoang TQ, Bluml S, Dubowitz DJ, et al. Quantitative proton-decoupled 31P MRS and 1H MRS in the evaluation of Huntington's and Parkinson's diseases. Neurology 1998;50:1033-1040.
-
(1998)
Neurology
, vol.50
, pp. 1033-1040
-
-
Hoang, T.Q.1
Bluml, S.2
Dubowitz, D.J.3
-
13
-
-
0031596998
-
1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers
-
Jenkins BG, Rosas HD, Chen YC, et al. 1H NMR spectroscopy studies of Huntington's disease: correlations with CAG repeat numbers. Neurology 1998;50:1357-1365.
-
(1998)
Neurology
, vol.50
, pp. 1357-1365
-
-
Jenkins, B.G.1
Rosas, H.D.2
Chen, Y.C.3
-
14
-
-
64949132814
-
Absolute metabolite concentrations calibrated using the total water signal in brain (1)H MRS
-
Brief EE, Moll R, Li DK, Mackay AL. Absolute metabolite concentrations calibrated using the total water signal in brain (1)H MRS. NMR Biomed 2009;22:349-354.
-
(2009)
NMR Biomed
, vol.22
, pp. 349-354
-
-
Brief, E.E.1
Moll, R.2
Li, D.K.3
Mackay, A.L.4
-
15
-
-
33744948153
-
Use of tissue water as a concentration reference for proton spectroscopic imaging
-
Gasparovic C, Song T, Devier D, et al. Use of tissue water as a concentration reference for proton spectroscopic imaging. Magn Reson Med 2006;55:1219-1226.
-
(2006)
Magn Reson Med
, vol.55
, pp. 1219-1226
-
-
Gasparovic, C.1
Song, T.2
Devier, D.3
-
16
-
-
33746220435
-
1H MR spectroscopy of the brain: absolute quantification of metabolites
-
Jansen JF, Backes WH, Nicolay K, Kooi ME. 1H MR spectroscopy of the brain: absolute quantification of metabolites. Radiology 2006;240:318-332.
-
(2006)
Radiology
, vol.240
, pp. 318-332
-
-
Jansen, J.F.1
Backes, W.H.2
Nicolay, K.3
Kooi, M.E.4
-
17
-
-
62049085680
-
Longitudinal diffusion tensor imaging in Huntington's disease
-
Weaver KE, Richards TL, Liang O, Laurino MY, Samii A, Aylward EH. Longitudinal diffusion tensor imaging in Huntington's disease. Exp Neurol 2009;216:525-529.
-
(2009)
Exp Neurol
, vol.216
, pp. 525-529
-
-
Weaver, K.E.1
Richards, T.L.2
Liang, O.3
Laurino, M.Y.4
Samii, A.5
Aylward, E.H.6
-
18
-
-
80052484592
-
Indexing disease progression at study entry with individuals at-risk for Huntington disease
-
Zhang Y, Long JD, Mills JA, Warner JH, Lu W, Paulsen JS. Indexing disease progression at study entry with individuals at-risk for Huntington disease. Am J Med Genet B Neuropsychiatr Genet 2011;156B:751-763.
-
(2011)
Am J Med Genet B Neuropsychiatr Genet
, vol.156 B
, pp. 751-763
-
-
Zhang, Y.1
Long, J.D.2
Mills, J.A.3
Warner, J.H.4
Lu, W.5
Paulsen, J.S.6
-
19
-
-
10744220393
-
Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study
-
Aylward EH, Rosenblatt A, Field K, et al. Caudate volume as an outcome measure in clinical trials for Huntington's disease: a pilot study. Brain Res Bull 2003;62:137-141.
-
(2003)
Brain Res Bull
, vol.62
, pp. 137-141
-
-
Aylward, E.H.1
Rosenblatt, A.2
Field, K.3
-
20
-
-
0031557092
-
Quantitative MRI volume changes in late onset schizophrenia and Alzheimer's disease compared to normal controls
-
Barta PE, Powers RE, Aylward E, et al. Quantitative MRI volume changes in late onset schizophrenia and Alzheimer's disease compared to normal controls. Psychiatry Res Neuroimaging 1997;68:65-75.
-
(1997)
Psychiatry Res Neuroimaging
, vol.68
, pp. 65-75
-
-
Barta, P.E.1
Powers, R.E.2
Aylward, E.3
-
21
-
-
1842504496
-
Glutamate concentrations in human brain using single voxel proton magnetic resonance spectroscopy at 3 Tesla
-
Schubert F, Gallinat J, Seifert F, Rinneberg H. Glutamate concentrations in human brain using single voxel proton magnetic resonance spectroscopy at 3 Tesla. Neuroimage 2004;21:1762-1771.
-
(2004)
Neuroimage
, vol.21
, pp. 1762-1771
-
-
Schubert, F.1
Gallinat, J.2
Seifert, F.3
Rinneberg, H.4
-
22
-
-
0027375098
-
Estimation of metabolite concentrations from localized in vivo proton NMR spectra
-
Provencher SW. Estimation of metabolite concentrations from localized in vivo proton NMR spectra. Magn Reson Med 1993;30:672-679.
-
(1993)
Magn Reson Med
, vol.30
, pp. 672-679
-
-
Provencher, S.W.1
-
23
-
-
2342467439
-
Quantitation of simulated short echo time 1H human brain spectra by LCModel and AMARES
-
Kanowski M, Kaufmann J, Braun J, Bernarding J, Tempelmann C. Quantitation of simulated short echo time 1H human brain spectra by LCModel and AMARES. Magn Reson Med 2004;51:904-912.
-
(2004)
Magn Reson Med
, vol.51
, pp. 904-912
-
-
Kanowski, M.1
Kaufmann, J.2
Braun, J.3
Bernarding, J.4
Tempelmann, C.5
-
24
-
-
0032542897
-
What's wrong with Bonferroni adjustments
-
Perneger TV. What's wrong with Bonferroni adjustments. BMJ 1998;316:1236-1238.
-
(1998)
BMJ
, vol.316
, pp. 1236-1238
-
-
Perneger, T.V.1
-
25
-
-
77950857170
-
Huntington's disease: pathogenesis to animal models
-
Kumar P, Kalonia H, Kumar A. Huntington's disease: pathogenesis to animal models. Pharmacol Rep 2010;62:1-14.
-
(2010)
Pharmacol Rep
, vol.62
, pp. 1-14
-
-
Kumar, P.1
Kalonia, H.2
Kumar, A.3
-
26
-
-
84862679900
-
Brain metabolite alterations and cognitive dysfunction in early Huntington's disease
-
Unschuld PG, Edden RA, Carass A, et al. Brain metabolite alterations and cognitive dysfunction in early Huntington's disease. Mov Disord 2012;27:895-902.
-
(2012)
Mov Disord
, vol.27
, pp. 895-902
-
-
Unschuld, P.G.1
Edden, R.A.2
Carass, A.3
-
27
-
-
0022395922
-
Neuropathological classification of Huntington's disease
-
Vonsattel JP, Myers RH, Stevens TJ, Ferrante RJ, Bird ED, Richardson EP Jr. Neuropathological classification of Huntington's disease. J Neuropathol Exp Neurol 1985;44:559-577.
-
(1985)
J Neuropathol Exp Neurol
, vol.44
, pp. 559-577
-
-
Vonsattel, J.P.1
Myers, R.H.2
Stevens, T.J.3
Ferrante, R.J.4
Bird, E.D.5
Richardson Jr., E.P.6
-
28
-
-
0032423104
-
No change in striatal glutamate in Huntington's disease measured by proton magnetic resonance spectroscopy
-
Clarke CE, Lowry M, Quarrell OW. No change in striatal glutamate in Huntington's disease measured by proton magnetic resonance spectroscopy. Parkinsonism Relay Disord 1998;4:123-127.
-
(1998)
Parkinsonism Relay Disord
, vol.4
, pp. 123-127
-
-
Clarke, C.E.1
Lowry, M.2
Quarrell, O.W.3
-
29
-
-
11144291556
-
Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease
-
Reynolds NC Jr, Prost RW, Mark LP. Heterogeneity in 1H-MRS profiles of presymptomatic and early manifest Huntington's disease. Brain Res 2005;1031:82-89.
-
(2005)
Brain Res
, vol.1031
, pp. 82-89
-
-
Reynolds Jr., N.C.1
Prost, R.W.2
Mark, L.P.3
-
30
-
-
0034118137
-
Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas
-
Shimizu H, Kumabe T, Shirane R, Yoshimoto T. Correlation between choline level measured by proton MR spectroscopy and Ki-67 labeling index in gliomas. AJNR Am J Neuroradiol 2000;21:659-665.
-
(2000)
AJNR Am J Neuroradiol
, vol.21
, pp. 659-665
-
-
Shimizu, H.1
Kumabe, T.2
Shirane, R.3
Yoshimoto, T.4
-
31
-
-
61449148438
-
Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease
-
Joshi PR, Wu NP, Andre VM, et al. Age-dependent alterations of corticostriatal activity in the YAC128 mouse model of Huntington disease. J Neurosci 2009;29:2414-2427.
-
(2009)
J Neurosci
, vol.29
, pp. 2414-2427
-
-
Joshi, P.R.1
Wu, N.P.2
Andre, V.M.3
-
32
-
-
81255149512
-
Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function
-
Raymond LA, Andre VM, Cepeda C, Gladding CM, Milnerwood AJ, Levine MS. Pathophysiology of Huntington's disease: time-dependent alterations in synaptic and receptor function. Neuroscience 2011;198:252-273.
-
(2011)
Neuroscience
, vol.198
, pp. 252-273
-
-
Raymond, L.A.1
Andre, V.M.2
Cepeda, C.3
Gladding, C.M.4
Milnerwood, A.J.5
Levine, M.S.6
-
33
-
-
0026043565
-
Chronic quinolinic acid lesions in rats closely resemble Huntington's disease
-
Beal MF, Ferrante RJ, Swartz KJ, Kowall NW. Chronic quinolinic acid lesions in rats closely resemble Huntington's disease. J Neurosci 1991;11:1649-1659.
-
(1991)
J Neurosci
, vol.11
, pp. 1649-1659
-
-
Beal, M.F.1
Ferrante, R.J.2
Swartz, K.J.3
Kowall, N.W.4
-
34
-
-
0025279038
-
A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon
-
Hantraye P, Riche D, Maziere M, Isacson O. A primate model of Huntington's disease: behavioral and anatomical studies of unilateral excitotoxic lesions of the caudate-putamen in the baboon. Exp Neurol 1990;108:91-104.
-
(1990)
Exp Neurol
, vol.108
, pp. 91-104
-
-
Hantraye, P.1
Riche, D.2
Maziere, M.3
Isacson, O.4
-
35
-
-
0036345741
-
Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation
-
Behrens PF, Franz P, Woodman B, Lindenberg KS, Landwehrmeyer GB. Impaired glutamate transport and glutamate-glutamine cycling: downstream effects of the Huntington mutation. Brain 2002;125(pt 8):1908-1922.
-
(2002)
Brain
, vol.125
, Issue.PT 8
, pp. 1908-1922
-
-
Behrens, P.F.1
Franz, P.2
Woodman, B.3
Lindenberg, K.S.4
Landwehrmeyer, G.B.5
-
36
-
-
62149084867
-
Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters
-
Estrada-Sanchez AM, Montiel T, Segovia J, Massieu L. Glutamate toxicity in the striatum of the R6/2 Huntington's disease transgenic mice is age-dependent and correlates with decreased levels of glutamate transporters. Neurobiol Dis 2009;34:78-86.
-
(2009)
Neurobiol Dis
, vol.34
, pp. 78-86
-
-
Estrada-Sanchez, A.M.1
Montiel, T.2
Segovia, J.3
Massieu, L.4
-
37
-
-
41949104569
-
Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse
-
Miller BR, Dorner JL, Shou M, et al. Up-regulation of GLT1 expression increases glutamate uptake and attenuates the Huntington's disease phenotype in the R6/2 mouse. Neuroscience 2008;153:329-337.
-
(2008)
Neuroscience
, vol.153
, pp. 329-337
-
-
Miller, B.R.1
Dorner, J.L.2
Shou, M.3
-
38
-
-
0025096709
-
What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies
-
Perry TL, Hansen S. What excitotoxin kills striatal neurons in Huntington's disease? Clues from neurochemical studies. Neurology 1990;40:20-24.
-
(1990)
Neurology
, vol.40
, pp. 20-24
-
-
Perry, T.L.1
Hansen, S.2
-
39
-
-
0023258197
-
Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain
-
Reynolds GP, Pearson SJ. Decreased glutamic acid and increased 5-hydroxytryptamine in Huntington's disease brain. Neurosci Lett 1987;78:233-238.
-
(1987)
Neurosci Lett
, vol.78
, pp. 233-238
-
-
Reynolds, G.P.1
Pearson, S.J.2
-
40
-
-
0023690166
-
NMDA receptor losses in putamen from patients with Huntington's disease
-
Young AB, Greenamyre JT, Hollingsworth Z, et al. NMDA receptor losses in putamen from patients with Huntington's disease. Science 1988;241:981-983.
-
(1988)
Science
, vol.241
, pp. 981-983
-
-
Young, A.B.1
Greenamyre, J.T.2
Hollingsworth, Z.3
-
41
-
-
0037322570
-
Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease
-
Cepeda C, Hurst RS, Calvert CR, et al. Transient and progressive electrophysiological alterations in the corticostriatal pathway in a mouse model of Huntington's disease. J Neurosci 2003;23:961-969.
-
(2003)
J Neurosci
, vol.23
, pp. 961-969
-
-
Cepeda, C.1
Hurst, R.S.2
Calvert, C.R.3
-
42
-
-
60849093185
-
Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease
-
Graham RK, Pouladi MA, Joshi P, et al. Differential susceptibility to excitotoxic stress in YAC128 mouse models of Huntington disease between initiation and progression of disease. J Neuroscience 2009;29:2193-2204.
-
(2009)
J Neuroscience
, vol.29
, pp. 2193-2204
-
-
Graham, R.K.1
Pouladi, M.A.2
Joshi, P.3
-
43
-
-
77955643169
-
Molecular mechanisms and potential therapeutical targets in Huntington's disease
-
Zuccato C, Valenza M, Cattaneo E. Molecular mechanisms and potential therapeutical targets in Huntington's disease. Physiol Rev 2010;90:905-981.
-
(2010)
Physiol Rev
, vol.90
, pp. 905-981
-
-
Zuccato, C.1
Valenza, M.2
Cattaneo, E.3
-
44
-
-
70049083077
-
Therapeutic interventions for symptomatic treatment in Huntington's disease [serial online]
-
Mestre T, Ferreira J, Coelho MM, Rosa M, Sampaio C. Therapeutic interventions for symptomatic treatment in Huntington's disease [serial online]. Cochrane Database Syst Rev 2009(3):CD006456.
-
(2009)
Cochrane Database Syst Rev
, Issue.3
-
-
Mestre, T.1
Ferreira, J.2
Coelho, M.M.3
Rosa, M.4
Sampaio, C.5
-
45
-
-
0030614782
-
In vivo measurement of T2 distributions and water contents in normal human brain
-
Whittall KP, MacKay AL, Graeb DA, Nugent RA, Li DK, Paty DW. In vivo measurement of T2 distributions and water contents in normal human brain. Magn Reson Med 1997;37:34-43.
-
(1997)
Magn Reson Med
, vol.37
, pp. 34-43
-
-
Whittall, K.P.1
MacKay, A.L.2
Graeb, D.A.3
Nugent, R.A.4
Li, D.K.5
Paty, D.W.6
-
46
-
-
0036160978
-
Normal-appearing white matter in multiple sclerosis has heterogeneous, diffusely prolonged T(2)
-
Whittall KP, MacKay AL, Li DK, Vavasour IM, Jones CK, Paty DW. Normal-appearing white matter in multiple sclerosis has heterogeneous, diffusely prolonged T(2). Magn Reson Med 2002;47:403-408.
-
(2002)
Magn Reson Med
, vol.47
, pp. 403-408
-
-
Whittall, K.P.1
MacKay, A.L.2
Li, D.K.3
Vavasour, I.M.4
Jones, C.K.5
Paty, D.W.6
-
47
-
-
0009762340
-
Nuclear statistics
-
Englewood Cliffs, NJ: Prentice Hall.
-
Wang CH, Willis DL, Loveland WD. Nuclear statistics. Radiotracer Methodology in the Biological, Environmental, and Physical Sciences. Englewood Cliffs, NJ: Prentice Hall; 1975:294-309.
-
(1975)
Radiotracer Methodology in the Biological, Environmental, and Physical Sciences
, pp. 294-309
-
-
Wang, C.H.1
Willis, D.L.2
Loveland, W.D.3
|