Contribution of environment and genetics to pancreatic cancer susceptibility

PLoS ONE

Volumn 9, Issue 3, 2014, Pages

  Hocevar, Barbara A ^a,c   Kamendulis, Lisa M ^a,c   Pu, Xinzhu ^a   Perkins, Susan M ^b,c   Wang, Zheng Yu ^b   Johnston, Erica L ^c   DeWitt, John M ^b   Li, Lang ^b,c   Loehrer, Patrick J ^b,c   Klaunig, James E ^a,c   Chiorean, E Gabriela ^c,d  

^a INDIANA UNIVERSITY   (United States)

^b INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GENOMIC DNA; MALONALDEHYDE; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER STAGING; CANCER SUSCEPTIBILITY; CARCINOGENESIS; CLINICAL ARTICLE; COMET ASSAY; CONTROLLED STUDY; CYP2A6 GENE; DNA DAMAGE; DNA ISOLATION; ENVIRONMENTAL FACTOR; ERCC4 GENE; FEMALE; GENETICS; GENOTYPE; HUMAN; LIFESTYLE; MALE; MIDDLE AGED; OXIDATIVE STRESS; PANCREAS CANCER; PILOT STUDY; SINGLE NUCLEOTIDE POLYMORPHISM; TNFA GENE; TUMOR GENE; VERY ELDERLY; CASE CONTROL STUDY; DEMOGRAPHY; ENVIRONMENT; GENETIC PREDISPOSITION; METABOLISM; PANCREAS TUMOR; PATHOLOGY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DEMOGRAPHY; DNA DAMAGE; ENVIRONMENT; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; MIDDLE AGED; OXIDATIVE STRESS; PANCREATIC NEOPLASMS; POLYMORPHISM, SINGLE NUCLEOTIDE; TUMOR MARKERS, BIOLOGICAL; YOUNG ADULT;

EID: 84924591951     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0090052     Document Type: Article

References (45)

1. Hezel AF, Kimmelamn AC, Stanger BZ, Bardeesy N, Depinho RA (2006) Genetics and biology of pancreatic ductal adenocarcinoma. Genes Dev 20: 1218-1249.
2. Siegel R, Naishadham D, Jemal A (2012) Cancer statistics, 2012. CA Cancer J Clin 62: 10-29.
3. Raimondi S, Maisonneuve P, Lowenfels AB (2009) Epidemiology of pancreatic cancer: an overview. Nat Rev Gastroenterol Hepatol 6: 699-708.
4. Maisonneuve P, Lowenfels AB (2010) Epidemiology of pancreatic cancer: an update. Dig Dis 28: 645-656.
5. Mena S, Ortega A, Estrela JM (2009) Oxidative stress in environmental-induced carcinogenesis. Mutat Res 674: 36-44.
6. Reuter S, Gupta SC, Chaturvedi MM, Aggarwal BB (2010) Oxidative stress, inflammation, and cancer: How are they linked? Free Radic Biol Med 49: 1603-1616.
7. Klaunig JE, Wang Z, Pu X, Zhou S (2011) Oxidative stress and oxidative damange in chemical carcinogenesis. Toxicol Appl Pharmacol 254: 86-99.
8. Paz-Elizur T, Sevilya Z, Leitner-Dagan Y, Elinger D, Roisman LC, et al. (2008) DNA repair of oxidative DNA damage in human carcinogenesis: potential application for cancer risk assessment and prevention. Cancer Lett 266: 60-72.
9. Klaunig JE, Kamendulis LM (2004) The role of oxidative stress in carcinogenesis. Annu Rev Pharmacol Toxicol 44: 239-267.
10. Fuss JO, Cooper PK (2006) DNA repair: Dynamic defenders against cancer and aging. PLos Biol 4: e203.
11. Rojas E, Lopez M, Valverde M (1999) Single cell gel electrophoresis assay: methodology and applications. J Chromatogr B Biomed Sci Appl 722: 225-254.
12. Weng H, Weng Z, Lu Y, Nakayama K, Morimoto K (2009) Effects of cigarette smoking, XRCC1 genetic polymorphisms, and age on basal DNA damage in human blood mononuclear cells. Mutat Res 679: 59-64.
13. Blasiak J, Arabski M, Krupa R, Wozniak K, Zadrozny M, et al. (2004) DNA damage and repair in type 2 diabetes mellitus. Mutat Res 554: 297-304.
14. Song F, Jia W, Yao Y, Hu Y, Lei L, et al. (2007) Oxidative stress, antioxidant status and DNA damage in patients with impaired glucose regulation and newly diagnosed Type 2 diabetes. Clin Sci (Lond) 112: 599-606..
15. Verlaan M, Roelofs HM, van-Schaik A, Wanten GJ, Jansen JB, et al. (2006) Assessment of oxidative stress in chronic pancreatitis patients. World J Gastroenterol 12: 5705-5710.
16. Koorstra JB, Hong SM, Shi C, Meeker AK, Ryu JK, et al. (2009) Widespread activation of the DNA damage response in human pancreatic intraepithelial neoplasia. Mod Pathol 22: 1439-1445.
17. Lister A, Nedjadi T, Kitteringham N, Campbell F, Costello E, et al. (2011) Nrf2 is overexpressed in pancreatic cancer: implications for cell proliferation and therapy. Mol Cancer 10: 37.
18. Duell EJ, Holly EA, Bracci PM, Liu M, Wiencke JK, et al. (2002) A population-based, case-control study of polymorphisms in carcinogen-metabolizing genes, smoking, and pancreatic adenocarcinoma risk. J Natl Cancer Inst 94: 297-306.
19. McWilliams RR, Bamlet WR, de Andrade M, Rider DN, Cunningham JM, et al. (2009) Nucleotide excision repair pathway polymorphisms and pancreatic cancer risk: evidence for role of MMS19L. Cancer Epidemiol Biomarkers Prev 18: 1295-1302.
20. Li D, Suzuki H, Liu B, Morris J, Liu J, et al. (2009) DNA repair gene polymorphisms and risk of pancreatic cancer. Clin Cancer Res 15: 740-746.
21. McWilliams RR, Bamlet WR, Cunningham JM, Goode EL, de Andrade M, et al. (2008) Polymorphisms in DNA repair genes, smoking, and pancreatic adenocarcinoma risk. Cancer Res 68: 4928-4935.
22. Duell EJ, Holly EA, Bracci PM, Wiencke JK, Kelsey KT (2002) A population-based study of the Arg399Gln polymorphism in X-ray repair cross-complementing group 1 (XRCC1) and risk of pancreatic adenocarcinoma. Cancer Res 62: 4630-4636.
23. Jiao L, Bondy ML, Hassan MM, Wolff RA, Evans DB, et al. (2006) Selected polymorphisms of DNA repair genes and risk of pancreatic cancer. Cancer Detect Prev 30: 284-291.
24. Jiao L, Bondy ML, Hassan MM, Chang DZ, Abbruzzese JL, et al. (2007) Glutathione S-transferase gene polymorphisms and risk and survival of pancreatic cancer. Cancer 109: 840-848.
25. Re R, Pellegrini N, Proteggente A, Pannala A, Yang M, et al. (1999) Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Rad Biol Med 26: 1231-1237.
26. Pu X, Kamendulis L, Klaunig J (2009) Acrylonitrile-induced oxidative stress and oxidative damage in male Sprague-Dawley rats. Toxicol Sci 111 64-71.
27. Vuppalanchi R, Juluri R, Bell L, Ghabril M, Kamendulis L, et al. (2011) Oxidative stress in chronic liver disease: Relationship between peripheral and hepatic measurements. Amer J Med Sci 342: 314-317.
28. Collins AR, Raslová K, Somorovská M, Petrovská H, Ondrusová A, et al. (1998) DNA damage in diabetes: correlation with a clinical marker. Free Radic Biol Med 25: 373-377.
29. Kushwaha S, Vikram A, Trivedi P, Jena G (2011) Alkaline, Endo III and FPG modified comet assay as biomarkers for the detection of oxidative DNA damage in rats with experimentally induced diabetes. Mutat Res 726: 242-250.
30. Pannuru P1, Vaddi DR, Kindinti RR, Varadacharyulu N (2011) Increased erythrocyte antioxidant status protects against smoking induced hemolysis in moderate smokers. Hum Exp Toxicol 30: 1475-1481.
31. Miri R, Saadati H, Ardi P, Firuzi O (2012) Alterations in oxidative stress biomakers associated with mild hyperlipidemia and smoking. Food Chem Toxicol 50: 920-926.
32. Xu C, Goodz S, Sellers EM, Tyndale RF (2002) CYP2A6 genetic variation and potential consequences. Adv Drug Deliv Rev 54: 1245-1256.
33. Sachse C, Smith G, Wilkie M, Barrett J, Waxman R, et al. (2002) A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer. Carcinogenesis 23: 1839-1849.
34. Hadidi H, Zahlsen K, Idle JR, Cholerton S (1997) A single amino acid substitution (Leu160His) in cytochrome P450 CYP2A6 causes switching from 7-hydroxylation to 3-hydroxylation of coumarin. Food Chem Toxicol 35: 903-907.
35. Rotunno M, Yu K, Lubin J, Consonni D, Pesatori A, et al. (2009) Phase I metabolic genes and risk of lung cancer: Multipple polymorphisms and mRNA expression. PLoS ONE 4: 1-13.
36. Kadlubar S, Anderson JP, Sweeney C, Gross MD, Lang NP, et al. (2009) Phenotypic CYP2A6 variation and the risk of pancreatic cancer. JOP 10: 263-270.
37. Qidwai T, Khan F (2011) Tumour necrosis factor gene polymorphism and disease prevalence. Scand J Immunol 74: 522-547.
38. Elahi MM, Asotra K, Matata BM, Mastana SS (2009) Tumor necrosis factor alpha 2308 gene locus promoter polymorphism: an analysis of association with health and disease. Biochim Biophys Acta 1792: 163-172.
39. Duell E, Casella D, Burk R, Kelsey K, Holly E (2006) Inflammation, genetic polymorphisms in proinflammatory genes TNF-A, RANTES, and CCR5, and risk of pancreatic adenocarcinoma. Cancer Epidemiol Biomarkers Prev 15: 726-731.
40. Kubaszek A, Pihlajamaki J, Komarovski V, Lindi V, Lindstrom J, et al. (2003) Promoter polymorphisms of the TNF-a (G-308A) and IL-6 (C-174G) genes predict the conversion from impaired glucose tolerance to type 2 diabetes: The Finnish diabetes prevention study. Diabetes 52: 1872-1876.
41. Ahmad A, Rasile Robinson A, Duensing A, van Drunen E, Beverloo H, et al. (2008) ERCC-XPF endonuclease facilitates DNA double-strand break repair. Mol Cell Biol 28: 5082-5092.
42. Sengerova S, Wang A, McHugh P (2011) Orchestrating the nucleases involved in DNA interstrand cross-link (ICL) repair. Cell Cycle 10: 3999-4008.
43. Smith T, Levine E, Perrier N, Miller M, Freimanis R, et al. (2003) DNA-repair genetic polymorphisms and breast cancer risk. Cancer Epidemiol Biomarkers Prev 12: 1200-1204.
44. Smith TR, Levine EA, Freimanis RI, Akman SA, Allen GO, et al. (2008) Polygenic model of DNA repair genetic polymorphisms in human breast cancer risk. Carcinogenesis 29: 2132-2138.
45. Jorgensen T, Helzlsouer K, Clipp S, Hoffman Bolton J, Crum R, et al. (2009) DNA repair gene variants associated with benign breast disease in high cancer risk women. Cancer Epidemiol Biomarkers Prev 18: 346-350.