Genetic deletion of the adaptor protein p66Shc increases susceptibility to short-term ischaemic myocardial injury via intracellular salvage pathways

European Heart Journal

Volumn 36, Issue 8, 2015, Pages 516-526

  Akhmedov, Alexander ^a   Montecucco, Fabrizio ^b,c,d   Braunersreuther, Vincent ^b   Camici, Giovanni G ^a   Jakob, Philipp ^a   Reiner, Martin F ^a   Glanzmann, Martina ^a   Burger, Fabienne ^b,c,d   Paneni, Francesco ^a,e   Galan, Katia ^b   Pelli, Graziano ^b   Vuilleumier, Nicolas ^f,g   Belin, Alexandre ^f   Vallée, Jean Paul ^f   Mach, Francois ^b   Lüscher, Thomas F ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b UNIVERSITY OF GENEVA   (Switzerland)

^c UNIVERSITY OF GENOA   (Italy)

^d UNIVERSITY OF GENOA   (Italy)

^e KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^f GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^g Geneva Hospitals and Faculty of Medicine   (Switzerland)

Author keywords

Acute myocardial infarction; Inflammation; Ischaemia; Reperfusion

Indexed keywords

ADAPTOR PROTEIN; ADAPTOR PROTEIN P66; CASPASE 3; OXIDIZING AGENT; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; BIOLOGICAL MARKER; PROTEIN SHC; SHC1 PROTEIN, MOUSE; STAT3 PROTEIN; STAT3 PROTEIN, MOUSE; TROPONIN I;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; DENSITY; GENE DELETION; GENETIC SUSCEPTIBILITY; HEART INFARCTION; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; INFLAMMATION; ISCHEMIC MYOCARDIAL INJURY; MALE; MITOCHONDRION SWELLING; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEFICIENCY; REPERFUSION INJURY; RESPIRATORY BURST; WILD TYPE; ANIMAL; C57BL MOUSE; DEFICIENCY; GENE SILENCING; GENETICS; HEART MUSCLE; HEART MUSCLE REPERFUSION; METABOLISM; PATHOLOGY; PROCEDURES; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; BIOMARKERS; GENE DELETION; GENE KNOCKDOWN TECHNIQUES; MALE; MAP KINASE SIGNALING SYSTEM; MICE, INBRED C57BL; MITOCHONDRIAL SWELLING; MYOCARDIAL REPERFUSION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; SHC SIGNALING ADAPTOR PROTEINS; STAT3 TRANSCRIPTION FACTOR; TROPONIN I;

EID: 84924587880     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehu400     Document Type: Article

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