Antibodies targeting Clec9A promote strong humoral immunity without adjuvant in mice and non-human primates

European Journal of Immunology

Volumn 45, Issue 3, 2015, Pages 854-864

  Li, Jessica ^a,b   Ahmet, Fatma ^a   Sullivan, Lucy C ^b   Brooks, Andrew G ^b   Kent, Stephen J ^b   De Rose, Robert ^b   Salazar, Andres M ^c   Reis e Sousa, Caetano ^d   Shortman, Ken ^a,b,e   Lahoud, Mireille H ^a,f   Heath, William R ^b   Caminschi, Irina ^a,b  

^a BURNET INSTITUTE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c Oncovir Inc   (United States)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

^e WALTER AND ELIZA HALL INSTITUTE OF MEDICAL RESEARCH   (Australia)

^f MONASH UNIVERSITY   (Australia)

Author keywords

Adjuvant; Clec9A; Dendritic cells; Humoral immunity; Non human primates; Vaccines

Indexed keywords

ADJUVANT; ANTIBODY; ANTIGEN; CD8ALPHA ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY CLEC9A; UNCLASSIFIED DRUG; CANCER VACCINE; CD8 ANTIGEN; CD8 ANTIGEN, ALPHA CHAIN; IMMUNOLOGICAL ADJUVANT; LECTIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; HELPER CELL; HUMORAL IMMUNITY; IMMUNOGENICITY; IN VIVO STUDY; MOUSE; MOUSE STRAIN; NONHUMAN; PRIMATE; PRIORITY JOURNAL; VACCINATION; ANIMAL; ANTIBODY COMBINING SITE; BAGG ALBINO MOUSE; DENDRITIC CELL; DRUG EFFECTS; HUMAN; IMMUNOLOGY; MACACA NEMESTRINA; NEOPLASMS; PATHOLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; ANTIGENS, CD8; BINDING SITES, ANTIBODY; CANCER VACCINES; DENDRITIC CELLS; HUMANS; IMMUNITY, HUMORAL; LECTINS, C-TYPE; MACACA NEMESTRINA; MICE; MICE, INBRED BALB C; NEOPLASMS;

EID: 84924535047     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445127     Document Type: Article

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