Minocycline Rescues from Zinc-Induced Nigrostriatal Dopaminergic Neurodegeneration: Biochemical and Molecular Interventions

Molecular Neurobiology

Volumn 53, Issue 5, 2016, Pages 2761-2777

  Kumar, Vinod ^a,b   Singh, Brajesh Kumar ^a   Chauhan, Amit Kumar ^a,b   Singh, Deepali ^a,b   Patel, Devendra Kumar ^a   Singh, Chetna ^a,b  

^a CSIR INDIAN INSTITUTE OF TOXICOLOGY RESEARCH   (India)

^b ACADEMY OF SCIENTIFIC AND INNOVATIVE RESEARCH ACSIR   (India)

Author keywords

Dopaminergic neurodegeneration; Microglia; Minocycline; Oxidative stress; Parkinson s disease; Zinc

Indexed keywords

CASPASE 3; CATALASE; CYTOCHROME C; DOPAMINE TRANSPORTER; HEME OXYGENASE 1; MINOCYCLINE; PROTEIN P67PHOX; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TYROSINE 3 MONOOXYGENASE; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; CARRIER PROTEIN; CD11B ANTIGEN; CELL NUCLEUS ANTIGEN; DOPAMINE; NERVE PROTEIN; NEUN PROTEIN, RAT; ZINC;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CELL COUNT; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC NERVE CELL; ENZYME ACTIVITY; LIPID PEROXIDATION; MALE; MICROGLIA; NEUROPATHOLOGY; NEUROPROTECTION; NONHUMAN; OXIDATIVE STRESS; PARKINSONISM; PROTEIN EXPRESSION; PROTEIN SECRETION; RAT; SUBSTANTIA NIGRA PARS COMPACTA; ANIMAL; ANIMAL BEHAVIOR; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; METABOLOME; MITOCHONDRION; MOTOR ACTIVITY; NERVE DEGENERATION; PATHOLOGY; PATHOPHYSIOLOGY; ROTAROD TEST; SUBSTANTIA NIGRA; WISTAR RAT;

ANIMALS; ANTIGENS, NUCLEAR; BEHAVIOR, ANIMAL; CASPASE 3; CD11B ANTIGEN; CYTOCHROMES C; DOPAMINE; DOPAMINERGIC NEURONS; GENE EXPRESSION REGULATION; HEME OXYGENASE-1; LIPID PEROXIDATION; MALE; MEMBRANE TRANSPORT PROTEINS; METABOLOME; MICROGLIA; MINOCYCLINE; MITOCHONDRIA; MOTOR ACTIVITY; NADPH OXIDASES; NERVE DEGENERATION; NERVE TISSUE PROTEINS; OXIDATIVE STRESS; RATS, WISTAR; ROTAROD PERFORMANCE TEST; SUBSTANTIA NIGRA; TYROSINE 3-MONOOXYGENASE; ZINC;

EID: 84924530451     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-015-9137-y     Document Type: Article

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