ApoA5 knockdown improves whole-body insulin sensitivity in high-fat-fed mice by reducing ectopic lipid content

Journal of Lipid Research

Volumn 56, Issue 3, 2015, Pages 526-536

  Camporez, João Paulo G ^a   Kanda, Shoichi ^a   Petersen, Max C ^a   Jornayvaz, François R ^a   Samuel, Varman T ^a   Bhanot, Sanjay ^b   Petersen, Kitt Falk ^a   Jurczak, Michael J ^a   Shulman, Gerald I ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ISIS PHARMACEUTICALS   (United States)

Author keywords

Apolipoprotein; Diacylglycerol; Dyslipidemias; Insulin resistance; Insulin signaling; Lipase lipoprotein; Lipid uptake; Nonalcoholic fatty liver disease; Protein kinase C

Indexed keywords

ACETYL COENZYME A SYNTHETASE; ANTISENSE OLIGONUCLEOTIDE; APOLIPOPROTEIN A5; DIACYLGLYCEROL; DIACYLGLYCEROL ACYLTRANSFERASE 2; FAS ANTIGEN; INSULIN; INTERLEUKIN 10; INTERLEUKIN 2; INTERLEUKIN 6; KERATINOCYTE DERIVED CHEMOKINE; LIPID; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; PROTEIN KINASE B BETA; PROTEIN KINASE C DELTA; PROTEIN KINASE C EPSILON; STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR ALPHA; AKT2 PROTEIN, MOUSE; APOA5 PROTEIN, MOUSE; APOLIPOPROTEIN; FAT INTAKE; PRKCE PROTEIN, MOUSE; PROTEIN KINASE B;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FAT CONTENT; GENE SILENCING; GLUCOSE CLAMP TECHNIQUE; INSULIN RESISTANCE; INSULIN RESPONSE; INSULIN SENSITIVITY; LIPID DIET; LIPID STORAGE; LIPID TRANSPORT; LIVER PARENCHYMA; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SKELETAL MUSCLE; TRIACYLGLYCEROL BLOOD LEVEL; ANIMAL; FAT INTAKE; GENETICS; LIVER; METABOLISM; PHARMACOLOGY;

ANIMALS; APOLIPOPROTEINS; DIETARY FATS; GENE KNOCKDOWN TECHNIQUES; INSULIN RESISTANCE; LIVER; MALE; MICE; MUSCLE, SKELETAL; PROTEIN KINASE C-EPSILON; PROTO-ONCOGENE PROTEINS C-AKT; TRIGLYCERIDES;

EID: 84924530326     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M054080     Document Type: Article

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