The tumor-suppressor gene LZTS1 suppresses colorectal cancer proliferation through inhibition of the AKT-mTOR signaling pathway

Cancer Letters

Volumn 360, Issue 1, 2015, Pages 68-75

  Zhou, Wei ^a   He, Mei Rong ^a   Jiao, Hong Li ^a   He, Liu Qing ^a   Deng, Dan Ling ^a   Cai, Juan Juan ^a   Xiao, Zhi Yuan ^a   Ye, Ya Ping ^a   Ding, Yan Qing ^a   Liao, Wen Ting ^a   Liu, Si De ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

AKT mTOR signaling; Colorectal cancer; LZTS1; Prognosis; Proliferation

Indexed keywords

CYCLIN D1; CYCLIN DEPENDENT KINASE INHIBITOR 1B; LEUCINE ZIPPER PROTEIN; LEUCINE ZIPPER SUPPRESSOR 1; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; LZTS1 PROTEIN, HUMAN; MTOR PROTEIN, HUMAN; TARGET OF RAPAMYCIN KINASE; TUMOR MARKER;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER CLASSIFICATION; CANCER GROWTH; CANCER INHIBITION; CANCER PROGNOSIS; CANCER STAGING; CANCER SURVIVAL; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLORECTAL CANCER; COLORECTAL CANCER CELL LINE; CONTROLLED STUDY; CORRELATIONAL STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISTANT METASTASIS; DOWN REGULATION; GENE; GENE FUNCTION; GENE IDENTIFICATION; GENE INTERACTION; GENE LOCATION; GENETIC MARKER; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LZTS1 GENE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION; TUMOR DIFFERENTIATION; TUMOR SUPPRESSOR GENE; TUMOR XENOGRAFT; UPREGULATION; ADULT; AGED; ANIMAL; BAGG ALBINO MOUSE; COLORECTAL TUMOR; FEMALE; GENETIC TRANSFECTION; GENETICS; HCT116 CELL LINE; HT 29 CELL LINE; KAPLAN MEIER METHOD; MALE; METABOLISM; MIDDLE AGED; MORTALITY; NUDE MOUSE; PATHOLOGY; PROGNOSIS; RNA INTERFERENCE; TIME; TUMOR VOLUME;

ADULT; AGED; ANIMALS; CELL PROLIFERATION; COLORECTAL NEOPLASMS; DNA-BINDING PROTEINS; FEMALE; HCT116 CELLS; HT29 CELLS; HUMANS; KAPLAN-MEIER ESTIMATE; MALE; MICE, INBRED BALB C; MICE, NUDE; MIDDLE AGED; PROGNOSIS; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TOR SERINE-THREONINE KINASES; TRANSFECTION; TUMOR BURDEN; TUMOR MARKERS, BIOLOGICAL; TUMOR SUPPRESSOR PROTEINS;

EID: 84924501652     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2015.02.004     Document Type: Article

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