FOXC2 promotes colorectal cancer proliferation through inhibition of FOXO3a and activation of MAPK and AKT signaling pathways

Cancer Letters

Volumn 353, Issue 1, 2014, Pages 87-94

  Cui, Yan Mei ^a   Jiang, Dan ^c   Zhang, Shi Hong ^b   Wu, Ping ^a   Ye, Ya Ping ^a   Chen, Cui Min ^a   Tang, Na ^a   Liang, Li ^a   Li, Ting Ting ^a   Qi, Lu ^a   Wang, Shu Yang ^a   Jiao, Hong Li ^a   Lin, Jie ^a   Ding, Yan Qing ^a   Liao, Wen Ting ^a  

^a SOUTHERN MEDICAL UNIVERSITY   (China)

^b THE FIRST AFFILIATED HOSPITAL OF SUN YAT SEN UNIVERSITY   (China)

^c SICHUAN UNIVERSITY   (China)

Author keywords

Colorectal cancer; FOXC2; Nuclear localization; Prognosis; Proliferation

Indexed keywords

CYCLIN D1; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; PROTEIN P27; TRANSCRIPTION FACTOR FKHRL1; TRANSCRIPTION FACTOR FOXC2; CCND1 PROTEIN, HUMAN; CDKN1B PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1B; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; ADVANCED CANCER; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER PROGNOSIS; CANCER STAGING; CARCINOGENESIS; CELL NUCLEUS; CELL PROLIFERATION; CELLULAR DISTRIBUTION; COLORECTAL CANCER; DISEASE FREE SURVIVAL; DISTANT METASTASIS; DOWN REGULATION; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; LYMPH NODE METASTASIS; MAJOR CLINICAL STUDY; MALE; MOUSE; NONHUMAN; OVERALL SURVIVAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH; UPREGULATION; ADENOCARCINOMA; ADOLESCENT; CACO 2 CELL LINE; COLORECTAL TUMOR; ENZYME ACTIVATION; ENZYMOLOGY; FOXC2; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HCT116 CELL LINE; HT 29 CELL LINE; METABOLISM; MIDDLE AGED; NUCLEAR LOCALIZATION; PATHOLOGY; PROGNOSIS; PROLIFERATION; RNA INTERFERENCE; TIME; YOUNG ADULT;

COLORECTAL CANCER; FOXC2; NUCLEAR LOCALIZATION; PROGNOSIS; PROLIFERATION;

ADENOCARCINOMA; ADOLESCENT; ADULT; AGED; CACO-2 CELLS; CELL PROLIFERATION; COLORECTAL NEOPLASMS; CYCLIN D1; CYCLIN-DEPENDENT KINASE INHIBITOR P27; DISEASE-FREE SURVIVAL; ENZYME ACTIVATION; FEMALE; FORKHEAD TRANSCRIPTION FACTORS; GENE EXPRESSION REGULATION, NEOPLASTIC; HCT116 CELLS; HT29 CELLS; HUMANS; MALE; MIDDLE AGED; MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION; TUMOR MARKERS, BIOLOGICAL; UP-REGULATION; YOUNG ADULT;

EID: 84908391456     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.07.008     Document Type: Article

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