Energy status and HIF signalling in chorionic villi show no evidence of hypoxic stress during human early placental development

Molecular Human Reproduction

Volumn 21, Issue 3, 2014, Pages 296-308

  Cindrova Davies, T ^a   Tissot Van Patot, M ^a   Gardner, L ^a   Jauniaux, E ^b   Burton, G J ^a   Charnock Jones, D S ^a,c  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^c The National Institute for Health Research Health Protection Research Unit in Blood Borne and Sexually Transmitted Infections at University College London in partnership with UK Health Security Agency   (United Kingdom)

Author keywords

Energy status; First trimester; HIF 1a; Metabolomics; Placenta

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 NITROPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ADENOSINE DIPHOSPHATE; GLUCOSE TRANSPORTER 3; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; NICOTINAMIDE ADENINE DINUCLEOTIDE; ADENOSINE TRIPHOSPHATE; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, HUMAN; HYDROGEN PEROXIDE; IMIDAZOLE DERIVATIVE; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGEN; PIGF PROTEIN, HUMAN; SLC2A3 PROTEIN, HUMAN; VASCULOTROPIN A; VEGFA PROTEIN, HUMAN;

ARTICLE; CESAREAN SECTION; CHORION VILLUS SAMPLING; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; FEMALE; FIRST TRIMESTER PREGNANCY; GESTATIONAL AGE; HUMAN; HUMAN TISSUE; HYPOXIA; PLACENTA DEVELOPMENT; PRIORITY JOURNAL; SECOND TRIMESTER PREGNANCY; SIGNAL TRANSDUCTION; STEADY STATE; WESTERN BLOTTING; ADULT; ANTAGONISTS AND INHIBITORS; CELL HYPOXIA; CHORION VILLUS; DRUG EFFECTS; ENERGY METABOLISM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; PHYSIOLOGY; PREGNANCY; PRIMARY CELL CULTURE; REPRODUCTION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ADULT; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL HYPOXIA; CHORIONIC VILLI; ENERGY METABOLISM; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GLUCOSE TRANSPORTER TYPE 3; HUMANS; HYDROGEN PEROXIDE; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; IMIDAZOLES; MEMBRANE PROTEINS; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PLACENTATION; PREGNANCY; PREGNANCY TRIMESTERS; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION; TRANSCRIPTION, GENETIC; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84924484457     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gau105     Document Type: Article

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