Role of Pentraxin 3 in Shaping Arthritogenic Alphaviral Disease: From Enhanced Viral Replication to Immunomodulation

PLoS Pathogens

Volumn 11, Issue 2, 2015, Pages

  Foo, Suan Sin ^a   Chen, Weiqiang ^a   Taylor, Adam ^a   Sheng, Kuo Ching ^a   Yu, Xing ^a   Teng, Terk Shin ^b   Reading, Patrick C ^c   Blanchard, Helen ^a   Garlanda, Cecilia ^d   Mantovani, Alberto ^d,e   Ng, Lisa F P ^b,f   Herrero, Lara J ^a   Mahalingam, Suresh ^a  

^a GRIFFITH UNIVERSITY   (Australia)

^b AGENCY FOR SCIENCE   (Singapore)

^c PETER DOHERTY INSTITUTE FOR INFECTION AND IMMUNITY   (Australia)

^d HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

^e UNIVERSITY OF MILAN   (Italy)

^f NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 6; MANNOSE BINDING LECTIN; MESSENGER RNA; PENTRAXIN 3; TUMOR NECROSIS FACTOR ALPHA; C REACTIVE PROTEIN; NERVE PROTEIN; NEURONAL PENTRAXIN; SERUM AMYLOID P; TRANSCRIPTOME;

ALPHAVIRUS INFECTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTHRITOGENIC ALPHAVIRAL DISEASE; ARTICLE; BINDING ASSAY; BLOOD SAMPLING; CELL CULTURE; CELL INFILTRATION; CHIKUNGUNYA ALPHAVIRUS; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DISEASE COURSE; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOFLUORESCENCE; IMMUNOMODULATION; INFLAMMATION; MALE; MOUSE; NONHUMAN; PREVALENCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; ROSS RIVER ALPHA VIRUS; VIRUS ENTRY; VIRUS LOAD; VIRUS REPLICATION; VIRUS TITRATION; VIRUS VIRULENCE; ANIMAL; C57BL MOUSE; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; KNOCKOUT MOUSE;

ALPHAVIRUS; CHIKUNGUNYA VIRUS; MUS; ROSS RIVER VIRUS;

ALPHAVIRUS INFECTIONS; ANIMALS; C-REACTIVE PROTEIN; CELLS, CULTURED; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NERVE TISSUE PROTEINS; REAL-TIME POLYMERASE CHAIN REACTION; SERUM AMYLOID P-COMPONENT; TRANSCRIPTOME; TRANSFECTION; VIRAL LOAD; VIRUS REPLICATION;

EID: 84924347577     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004649     Document Type: Article

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