Activation of mu-opioid receptors in the ventrolateral orbital cortex inhibits the GABAergic miniature inhibitory postsynaptic currents in rats

Neuroscience Letters

Volumn 592, Issue , 2015, Pages 64-69

  Qu, Chao Ling ^a   Huo, Fu Quan ^a   Huang, Fen Sheng ^b   Tang, Jing Shi ^a  

^a MEDICAL SCHOOL OF XI AN JIAOTONG UNIVERSITY   (China)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

GABA; MIPSCs; Mu opioid receptor; Rats; Ventrolateral orbital cortex

Indexed keywords

4 AMINOBUTYRIC ACID RECEPTOR; BICUCULLINE; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; KYNURENIC ACID; MU OPIATE RECEPTOR; POSTSYNAPTIC RECEPTOR; PRESYNAPTIC RECEPTOR; 4 AMINOBUTYRIC ACID; PHENYLALANYL-CYCLO(CYSTEINYLTYROSYL-TRYPTOPHYL-ORNITHYL-THREONYL-PENICILLAMINE)THREONINAMIDE; SOMATOSTATIN;

4 AMINOBUTYRIC ACID RELEASE; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; COMPARATIVE STUDY; CONTROLLED STUDY; NONHUMAN; ORBITAL CORTEX; POSTSYNAPTIC INHIBITION; PRESYNAPTIC INHIBITION; PRIORITY JOURNAL; RAT; VENTROLATERAL ORBITAL CORTEX; WHOLE CELL PATCH CLAMP; AGONISTS; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS; IN VITRO STUDY; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; MINIATURE ENDPLATE POTENTIAL; NERVE CELL; PATCH CLAMP TECHNIQUE; PHYSIOLOGY; PREFRONTAL CORTEX; SPRAGUE DAWLEY RAT;

ANIMALS; ENKEPHALIN, ALA(2)-MEPHE(4)-GLY(5)-; GAMMA-AMINOBUTYRIC ACID; IN VITRO TECHNIQUES; INHIBITORY POSTSYNAPTIC POTENTIALS; MINIATURE POSTSYNAPTIC POTENTIALS; NEURONS; PATCH-CLAMP TECHNIQUES; PREFRONTAL CORTEX; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID, MU; SOMATOSTATIN;

EID: 84924300026     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2015.02.045     Document Type: Article

References (24)

1. Burkey A.R., Carstens E., Wenniger J.J., Tang J., Jasmin L. An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception. J. Neurosci. 1996, 16:6612-6623.
2. Caudle R.M., Chavkin C. Mu opioid receptor activation reduces inhibitory postsynaptic potentials in hippocampal CA3 pyramidal cells of rat and guinea pig. J. Pharmacol. Exp. Ther. 1990, 252:1361-1369.
3. Esclapez M., Campistron G., Trottier S. Immunocytochemical localization and morphology of GABA-containing neurons in the prefrontal and frontoparietal cortex of the rat. Neurosci. Lett. 1987, 77:131-136.
4. Fields H.L., Heinricher M.M., Mason P. Neurotransmitters in nociceptive modulatory circuits. Annu. Rev. Neurosci. 1991, 14:219-245.
5. Fukuhara K., Katafuchi T., Yoshimura M. Effects of baclofen on mechanical noxious and innocuous transmission in the spinal dorsal horn of the adult rat: in vivo patch-clamp analysis. Eur. J. Neurosci. 2013, 38:3398-3407.
6. Hahm E.T., Kim Y., Lee J.J., Cho Y.W. GABAergic synaptic response and its opioidergic modulation in periaqueductal gray neurons of rats with neuropathic pain. BMC Neurosci. 2011, 12:41.
7. Hahm E.T., Lee J.J., Min B.I., Cho Y.W. Opioid inhibition of GABAergic neurotransmission in mechanically isolated rat periaqueductal gray neurons. Neurosci. Res. 2004, 50:343-354.
8. Hiller J.M., Zhang Y., Bing G., Gioannini T.L., Stone E.A., Simon E.J. Immunohistochemical localization of mu-opioid receptors in rat brain using antibodies generated against a peptide sequence present in a purified mu-opioid binding protein. Neuroscience 1994, 62:829-841.
9. Huang F.S., Meng K., Tang J.S. Properties of paired-pulse firing thresholds and the relationship with paired-pulse plasticity in hippocampal CA3-CA1 synapses. Eur. J. Neurosci. 2007, 25:3253-3263.
10. Huang X., Tang J.S., Yuan B., Jia H. Morphine applied to the ventrolateral orbital cortex produces a naloxone-reversible antinociception in the rat. Neurosci. Lett. 2001, 299:189-192.
11. Huo F.Q., Wang J., Li Y.Q., Chen T., Han F., Tang J.S. GABAergic neurons express mu-opioid receptors in the ventrolateral orbital cortex of the rat. Neurosci. Lett. 2005, 382:265-268.
12. Kawaguchi Y., Shindou T. Noradrenergic excitation and inhibition of GABAergic cell types in rat frontal cortex. J. Neurosci. 1998, 18:6963-6976.
13. Kishimoto K., Koyama S., Akaike N. Synergistic mu-opioid and 5-HT1A presynaptic inhibition of GABA release in rat periaqueductal gray neurons. Neuropharmacology 2001, 41:529-538.
14. Loose M.D., Kelly M.J. Opioids act at mu-receptors to hyperpolarize arcuate neurons via an inwardly rectifying potassium conductance. Brain Res. 1990, 513:15-23.
15. Mansour A., Khachaturian H., Lewis M.E., Akil H., Watson S.J. Autoradiographic differentiation of mu, delta, and kappa opioid receptors in the rat forebrain and midbrain. J. Neurosci. 1987, 7:2445-2464.
16. McGinty J.F., van der Kooy D., Bloom F.E. The distribution and morphology of opioid peptide immunoreactive neurons in the cerebral cortex of rats. J. Neurosci. 1984, 4:1104-1117.
17. Mouginot D., Kombian S.B., Pittman Q.J. Activation of presynaptic GABAB receptors inhibits evoked IPSCs in rat magnocellular neurons in vitro. J. Neurophysiol. 1998, 79:1508-1517.
18. Ponterio G., Tassone A., Sciamanna G., Riahi E., Vanni V., Bonsi P., Pisani A. Powerful inhibitory action of mu opioid receptors (MOR) on cholinergic interneuron excitability in the dorsal striatum. Neuropharmacology 2013, 75:78-85.
19. Qu C.L., Tang J.S., Jia H. Involvement of GABAergic modulation of antinociception induced by morphine microinjected into the ventrolateral orbital cortex. Brain Res. 2006, 1073-1074:281-289.
20. Sandkuhler J., Gebhart G.F. Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and laterally in the midbrain and medulla in the pentobarbital-anesthetized rat. Brain Res. 1984, 305:67-76.
21. Seamans J.K., Gorelova N., Durstewitz D., Yang C.R. Bidirectional dopamine modulation of GABAergic inhibition in prefrontal cortical pyramidal neurons. J. Neurosci. 2001, 21:3628-3638.
22. Tang J.S., Qu C.L., Huo F.Q. The thalamic nucleus submedius and ventrolateral orbital cortex are involved in nociceptive modulation: a novel pain modulation pathway. Prog. Neurobiol. 2009, 89:383-389.
23. Thompson S.M., Capogna M., Scanziani M. Presynaptic inhibition in the hippocampus. Trends Neurosci. 1993, 16:222-227.
24. Xiao C., Gu Y., Zhou C.Y., Wang L., Zhang M.M., Ruan D.Y. Pb2+ impairs GABAergic synaptic transmission in rat hippocampal slices: a possible involvement of presynaptic calcium channels. Brain Res. 2006, 1088:93-100.