Pb2+ impairs GABAergic synaptic transmission in rat hippocampal slices: A possible involvement of presynaptic calcium channels

Brain Research

Volumn 1088, Issue 1, 2006, Pages 93-100

  Xiao, Cheng ^a   Gu, Yan ^a   Zhou, Chun Yi ^a   Wang, Lang ^a   Zhang, Min Min ^a   Ruan, Di Yun ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

GABAA receptor; Hippocampal slice; Inhibitory postsynaptic current; Pb2+; Voltage gated calcium channel

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; CALCIUM CHANNEL; LEAD; VOLTAGE GATED CALCIUM CHANNEL; 4 AMINOBUTYRIC ACID; 4 AMINOBUTYRIC ACID RECEPTOR BLOCKING AGENT; BICUCULLINE; CADMIUM; CALCIUM; TETRODOTOXIN;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN SLICE; GABAERGIC SYSTEM; HIPPOCAMPUS; IC 50; INHIBITORY POSTSYNAPTIC POTENTIAL; MALE; NONHUMAN; PATCH CLAMP; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; RAT; SYNAPTIC TRANSMISSION; ANIMAL; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; IN VITRO STUDY; METABOLISM; METHODOLOGY; NERVE CELL; NERVE CELL INHIBITION; NEWBORN; PHYSIOLOGY; SYNAPTOSOME; WISTAR RAT;

ANIMALS; ANIMALS, NEWBORN; BICUCULLINE; CADMIUM; CALCIUM; CALCIUM CHANNELS; DOSE-RESPONSE RELATIONSHIP, DRUG; GABA ANTAGONISTS; GAMMA-AMINOBUTYRIC ACID; HIPPOCAMPUS; LEAD; MALE; NEURAL INHIBITION; NEURONS; PATCH-CLAMP TECHNIQUES; PRESYNAPTIC TERMINALS; RATS; RATS, WISTAR; SYNAPTIC TRANSMISSION; TETRODOTOXIN;

EID: 33747449286     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2006.03.005     Document Type: Article

References (47)

1. Aaron G.B., Wilcox K.S., and Dichter M.A. Different patterns of synaptic transmission revealed between hippocampal CA3 stratum oriens and stratum lucidum interneurons and their pyramidal cell targets. Neuroscience 117 (2003) 169-181
2. Alkondon M., Pereira E.F.R., Barbosa C.T.F., and Albuquerque E.X. Neuronal nicotinic acetylcholine receptor activation modulates γ-aminobutyric acid release from CA1 neurons of rat hippocampal slices. J. Pharmacol. Exp. Ther. 283 (1997) 1396-1411
3. Atchison W.D. Effects of toxic environmental contaminants on voltage-gated calcium channels function: from past to present. J. Bioenerg. Biomembr. 35 (2003) 507-532
4. Audesirk G. Electrophysiology of lead intoxication: effects on voltage-sensitive ion channels. Neurotoxicology 14 (1993) 137-148
5. Bliss T.V.P., and Collingridge G.L. A synaptic model of memory: long-term potentiation in the hippocampus. Nature 361 (1993) 31-39
6. Braga M.F., Pereira E.F., Marchioro M., and Albuquerque E.X. Lead increases tetrodotoxin-insensitive spontaneous release of glutamate and GABA from hippocampal neurons. Brain Res. 826 (1999) 10-21
7. Braga M.F., Pereira E.F., and Albuquerque E.X. Nanomolar concentrations of lead inhibit glutamatergic and GABAergic transmission in hippocampal neurons. Brain Res. 826 (1999) 22-34
8. Bragin A., Jando G., Nadasdy Z., Hetke J., Wise K., and Buzsaki G. Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat. J. Neurosci. 15 (1995) 47-60
9. Bressler J., Kim K., Chakraborti T., and Goldstein G. Molecular mechanisms of lead neurotoxicity. Neurochem. Res. 24 (1999) 595-600
10. Büsselberg D. Calcium channels as target sites of heavy metals. Toxicol. Lett. 82-83 (1995) 255-261
11. Buzsaki G., and Chrobak J.J. Temporal structure in spatially organized neuronal ensembles: a role for interneuron networks. Curr. Opin. Neurobiol. 5 (1995) 504-510
12. Cobb S.R., Buhl E.H., Halasy K., Paulsen O., and Somogyi P. Synchronization of neuronal activity in hippocampus by individual GABAergic interneurons. Nature 378 (1995) 75-78
13. Creager R., Dunwiddie T., and Lynch G. Paired-pulse and frequency facilitation in the CA1 region of the in vitro rat hippocampus. J. Physiol. 299 (1980) 409-424
14. Debanne D., Guerineau N.C., Gahwiler B.H., and Thompson S.M. Paired-pulse facilitation and depression at unitary synapses in rat hippocampus: quantal fluctuation affects subsequent release. J. Physiol. 491 (1996) 163-176
15. Drew C.A., Spence I., and Johnston G.A. Effects of lead salts on the uptake, release, and binding of gamma-aminobutyric acid: the importance of buffer composition. J. Neurochem. 52 (1989) 433-440
16. Finkelstein Y., Markowitz M.E., and Rosen J.F. Low-level lead induced neurotoxicity in children: an update on central nervous system effects. Brain Res. Rev. 27 (1998) 168-176
17. Giustizieri M., Bernardi G., Mercuri N.B., and Berretta N. Distinct mechanisms of presynaptic inhibition at GABAergic synapses of the rat substantia nigra pars compacta. J. Neurophysiol. 94 (2005) 1992-2003
18. Hamill O.P., Marty A., Neher E., Sakmann B., and Sigworth F.J. Improved patch-clamp techniques for high-resolution current recording from cells and cell-free membrane patches. Pflügers Arch. 391 (1981) 85-100
19. Healy M.A., Aslam M., Harrison P.G., and Fernando N.P. Lead-induced convulsions in young infants-a case history and the role of GABA and sodium valproate in the pathogenesis and treatment. J. Clin. Hosp. Pharm. 9 (1984) 199-207
20. Hwang T.N., and Copenhagen D.R. Automatic detection, characterization, and discrimination of kinetically distinct spontaneous synaptic events. J. Neurosci. Method 92 (1999) 65-73
21. Hyman J.M., Wyble B.P., Goyal V., Rossi C.A., and Hasselmo M.E. Stimulation in hippocampal region CA1 in behaving rats yields long-term potentiation when delivered to the peak of theta and long-term depression when delivered to the trough. J. Neurosci. 23 (2003) 11725-11731
22. Jefferys J.G.R., Traub R.D., and Whittington M.A. Neuronal networks for induced '40 Hz' rhythms. Trends Neurosci. 19 (1996) 202-208
23. Krishnamoorthy M.S., Parthiban N., Muthu P., Paul V., Balagopal G., and Kumaravel T.S. Effect of acute pretreatment of lead on picrotoxin-induced convulsions in rats. J. Appl. Toxicol. 13 (1993) 155-159
24. Lasley S.M., and Gilbert M.E. Presynaptic glutamatergic function in dentate gyrus in vivo is diminished by chronic exposure to inorganic lead. Brain Res. 736 (1996) 125-134
25. Lasley S.M., Green M.C., and Gilbert M.E. Influence of exposure period on in vivo hippocampal glutamate and GABA release in rats chronically exposed to lead. Neurotoxicology 20 (1999) 619-629
26. Lasley S.M., and Gilbert M.E. Glutamatergic components underlying lead-induced impairments in hippocampal synaptic plasticity. Neurotoxicology 21 (2000) 1057-1068
27. Lasley S.M., and Gilbert M.E. Rat hippocampal glutamate and GABA release exhibit biphasic effects as a function of chronic lead exposure level. Toxicol. Sci. 66 (2002) 139-147
28. Li Y.X., Zhang Y., Lester H.A., Schuman E.M., and Davidson N. Enhancement of neurotransmitter release induced by brain-derived neurotrophic factor in cultured hippocampal neurons. J. Neurosci. 18 (1998) 10231-10240
29. Lidsky T.I., and Schneider J.S. Lead neurotoxicity in children: basic mechanisms and clinical correlates. Brain 126 (2003) 5-19
30. Marchetti C. Molecular targets of lead in brain neurotoxicity. Neurotox. Res. 5 (2003) 1-15
31. 2+ permeation in rat cerebellar granule neurons. J. Neurochem. 79 (2001) 407-416
32. Memo M., Lucchi L., Spano P.F., and Trabucchi M. Effect of chronic lead treatment on GABA-ergic receptor function in rat brain. Toxicol. Lett. 6 (1980) 427-432
33. Mennerick S., and Zorumski C.F. Presynaptic influence on the time course of fast excitatory synaptic currents in cultured hippocampal cells. J. Neurosci. 15 (1995) 3178-3192
34. Minnema D.J., and Michaelson I.A. Differential effects of inorganic lead and delta-aminolevulinic acid in vitro on synaptosomal gamma-aminobutyric acid release. Toxicol. Appl. Pharmacol. 86 (1986) 437-447
35. Nachshen D.A. Selectivity of the Ca binding site in synaptosome Ca channels: inhibition of Ca influx by multivalent metal caitons. J. Gen. Physiol. 83 (1984) 941-967
36. Poncer J.C., McKinney R.A., Gähwiler B.H., and Thompson S.M. Either N- or P-type calcium channels mediate GABA release at distinct hippocampal inhibitory synapses. Neuron 18 (1997) 463-472
37. Soltesz I., and Deschenes M. Low- and high-frequency membrane potential oscillations during theta activity in CA1 and CA3 pyramidal neurons of the rat hippocampus under ketamine-xylazine anesthesia. J. Neurophysiol. 70 (1993) 97-116
38. Spence I., Drew C., Johnston G.A., and Lodge D. Acute effects of lead at central synapses in vitro. Brain Res. 333 (1985) 103-109
39. Squire L.R. Memory and the hippocampus: a synthesis from findings with rats, monkeys and humans. Psychol. Rev. 99 (1992) 195-231
40. Strużyñska L., and Rafalowska U. The effect of lead on dopamine, GABA and histidine spontaneous and KCl-dependent releases from rat brain synaptosomes. Acta Neurobiol. Exp. (Wars.) 54 (1994) 201-207
41. Strużyñska L., and Sulkowski G. Relationships between glutamine, glutamate, and GABA in nerve endings under Pb-toxicity conditions. J. Inorg. Biochem. 98 (2004) 951-958
42. Sullivan J.M. Mechanisms of cannabinoid-receptor-mediated inhibition of synaptic transmission in cultured hippocampal pyramidal neurons. J. Neurophysiol. 82 (1999) 1286-1294
43. 2+ on protein kinase C isozymes. Toxicol. Appl. Pharmacol. 156 (1999) 140-145
44. Suszkiw J.B. Presynaptic disruption of transmitter release by lead. Neurotoxicology 25 (2004) 599-604
45. Takahashi T., and Momiyama A. Different types of calcium channels mediate central synaptic transmission. Nature 366 (1993) 156-158
46. Tiffany-Castiglioni E., and Qian Y. Astroglia as metal depots: molecular mechanisms for metal accumulation, storage and release. Neurotoxicology 22 (2001) 577-592
47. Whittington M.A., Traub R.D., and Jefferys J.G. Synchronized oscillations in interneuron networks driven by metabotropic glutamate receptor activation. Nature 373 (1995) 612-615