Morphine applied to the ventrolateral orbital cortex produces a naloxone-reversible antinociception in the rat

Neuroscience Letters

Volumn 299, Issue 3, 2001, Pages 189-192

  Huang, Xin ^a   Tang, Jing Shi ^a   Yuan, Bin ^a   Jia, Hong ^a  

^a XI'AN JIAOTONG UNIVERSITY   (China)

Author keywords

Morphine; Naloxone; Nociceptive modulation; Rat; Tail flick reflex; Ventrolateral orbital cortex

Indexed keywords

MORPHINE; NALOXONE; OPIATE RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINOCICEPTION; ARTICLE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG MECHANISM; FEEDBACK SYSTEM; NEUROTRANSMISSION; NONHUMAN; ORBITAL CORTEX; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; RAT; TAIL FLICK TEST; THALAMUS VENTRAL NUCLEUS;

ANALGESICS, OPIOID; ANIMALS; DRUG INTERACTIONS; FEMALE; MALE; MORPHINE; NALOXONE; NARCOTIC ANTAGONISTS; NEURAL PATHWAYS; NOCICEPTORS; PAIN; PAIN MEASUREMENT; PREFRONTAL CORTEX; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, OPIOID; REFLEX;

EID: 0035937051     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3940(01)01497-5     Document Type: Article

References (19)

1. Endogenous pain control system: Brainstem spinal pathway and endorphin circuitry
2. An opioidergic cortical antinociception triggering site in the agranular insular cortex of the rat that contributes to morphine antinociception
3. Retrograde tracing of projections between the nucleus submedius, the ventrolateral orbital cortex and the midbrain in the rat
4. Spinal and medullary lamina I projection to nucleus submedius in medial thalamus: A possible pain center
5. The thalamocortical projection of the nucleus submedius in the cat
6. Frontal cortex projections to the periaquedactal gray in the rat: A retrograde and orthograde horseradish peroxidase study
7. μ-Opioid receptor mRNA expression in the rat SNC: Comparison to μ-receptor binding
8. The distribution and morphology of opioid peptide immunoreactive neurons in the cerebral cortex of rats
9. Characterization of inhibition of a spinal nociceptive reflex by stimulation medially and laterally in the midbrain and medulla in the pentobarbital-anesthetized rat
10. The effects of morphine on responses of ventrolateral orbital cortex (VLO) neurons to colorectal distension in the rat
11. Trigeminal projections to the nucleus submedius of the thalamus in the rat
12. The afferent and efferent connections of the nucleus submedius in the rat
13. Involvement of the frontal ventrolateral orbital cortex in descending inhibition of nociception mediated by the periaqueductal gray
14. Inhibitory effects of electrical stimulation of ventrolateral orbital cortex on the rat jaw-opening reflex
15. Inhibitory effects of glutamate-induced activation of thalamic nucleus submedius are mediated by ventrolateral orbital cortex and periaqueductal gray in rats
16. Electrically-evoked inhibitory effects of the nucleus submedius on the jaw-opening reflex are mediated by ventrolateral orbital cortex and periaqueductal gray matter in the rat
17. Inhibitory effects of electrical stimulation of thalamic nucleus submedius area on the rat tail flick reflex
18. Inhibitory effects of electrically evoked activation of ventrolateral orbital cortex on the tail-flick reflex are mediated by periaqueductal gray in rats