Early high protein intake is associated with low mortality and energy overfeeding with high mortality in non-septic mechanically ventilated critically ill patients

Critical Care

Volumn 18, Issue 1, 2014, Pages

  Weijs, Peter ^a,b   Looijaard, Wilhelmus ^a   Beishuizen, Albertus ^a,c   Girbes, Armand ^a   Oudemans van Straaten, Heleen M ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b AMSTERDAM UNIVERSITY OF APPLIED SCIENCES   (Netherlands)

^c MEDISCH SPECTRUM TWENTE   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; APACHE; ARTICLE; ARTIFICIAL VENTILATION; CALORIC INTAKE; CRITICALLY ILL PATIENT; ENERGY EXPENDITURE; FEMALE; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MALNUTRITION; MORTALITY; OVERNUTRITION; PRIORITY JOURNAL; PROSPECTIVE STUDY; PROTEIN INTAKE; RISK FACTOR; SEPSIS; VENTILATED PATIENT; ADMINISTRATION AND DOSAGE; AGED; COHORT ANALYSIS; CRITICAL ILLNESS; METABOLISM; MIDDLE AGED; PHYSIOLOGY; TRENDS; VERY ELDERLY;

PROTEIN INTAKE;

ADULT; AGED; AGED, 80 AND OVER; COHORT STUDIES; CRITICAL ILLNESS; DIETARY PROTEINS; ENERGY INTAKE; FEMALE; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; OVERNUTRITION; PROSPECTIVE STUDIES; RESPIRATION, ARTIFICIAL;

EID: 84924263136     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-014-0701-z     Document Type: Article

References (32)

1. Casaer MP, Mesotten D, Hermans G, Wouters PJ, Schetz M, Meyfroidt G, Van Cromphaut S, Ingels C, Meersseman P, Muller J, Vlasselaers D, Debaveye Y, Desmet L, Dubois J, Van Assche A, Vanderheyden S, Wilmer A, Van den Berghe G: Early versus late parenteral nutrition in critically ill adults. N Engl J Med 2011, 365:506-517.
2. Doig GS, Simpson F, Sweetman EA, Finfer SR, Cooper DJ, Heighes PT, Davies AR, O'Leary M, Solano T, Peake S: Early parenteral nutrition in critically ill patients with short-term relative contraindications to early enteral nutrition: a randomized controlled trial. JAMA 2013, 309:2130-2138.
3. Arabi YM, Tamim HM, Dhar GS, Al-Dawood A, Al-Sultan M, Sakkijha MH, Kahoul SH, Brits R: Permissive underfeeding and intensive insulin therapy in critically ill patients: a randomized controlled trial. Am J Clin Nutr 2011, 93:569-577.
4. Rice TW, Wheeler AP, Thompson BT, Steingrub J, Hite RD, Moss M, Morris A, Dong N, Rock P: Initial trophic vs full enteral feeding in patients with acute lung injury: the EDEN randomized trial. JAMA 2012, 307:795-803.
5. Fraipont V, Preiser JC: Energy estimation and measurement in critically ill patients. JPEN J Parenter Enteral Nutr 2013, 37:705-713.
6. van Schijndel RJMS, Weijs PJM, Koopmans RH, Sauerwein HP, Beishuizen A, Girbes ARJ: Optimal nutrition during the period of mechanical ventilation decreases mortality in critically ill, long-term acute female patients: a prospective observational cohort study. Crit Care 2009, 13:R132.
7. Weijs PJM, Stapel SN, de Groot SDW, Driessen RH, de Jong E, Girbes ARJ, van Schijndel RJMS, Beishuizen A: Optimal protein and energy nutrition decreases mortality in mechanically ventilated, critically ill patients: a prospective observational cohort study. JPEN J Parenter Enteral Nutr 2012, 36:60-68.
8. Allingstrup MJ, Esmailzadeh N, Wilkens Knudsen A, Espersen K, Hartvig Jensen T, Wiis J, Perner A, Kondrup J: Provision of protein and energy in relation to measured requirements in intensive care patients. Clin Nutr 2012, 31:462-468.
9. Elke G, Wang M, Weiler N, Day AG, Heyland DK: Close to recommended caloric and protein intake by enteral nutrition is associated with better clinical outcome of critically ill septic patients: secondary analysis of a large international nutrition database. Crit Care 2014, 18:R29.
10. Singer P, Hiesmayr M, Biolo G, Felbinger TW, Berger MM, Goeters C, Kondrup J, Wunder C, Pichard C: Pragmatic approach to nutrition in the ICU: expert opinion regarding which calorie protein target. Clin Nutr 2014, 33:246-251.
11. Vanhorebeek I, Gunst J, Derde S, Derese I, Boussemaere M, Guiza F, Martinet W, Timmermans JP, D'Hoore A, Wouters PJ, Van den Berghe G: Insufficient activation of autophagy allows cellular damage to accumulate in critically ill patients. J Clin Endocrinol Metab 2011, 96:E633-E645.
12. Casaer MP, Wilmer A, Hermans G, Wouters PJ, Mesotten D, Van den Berghe G: Role of disease and macronutrient dose in the randomized controlled EPaNIC trial: a post hoc analysis. Am J Respir Crit Care Med 2013, 187:247-255.
13. Puthucheary ZA, Rawal J, McPhail M, Connolly B, Ratnayake G, Chan P, Hopkinson NS, Padhke R, Dew T, Sidhu PS, Velloso C, Seymour J, Agley CC, Selby A, Limb M, Edwards LM, Smith K, Rowlerson A, Rennie MJ, Moxham J, Harridge SDR, Hart N, Montgomery HE: Acute skeletal muscle wasting in critical illness. JAMA 2013, 310:1591-1600.
14. Derde S, Vanhorebeek I, Guiza F, Derese I, Gunst J, Fahrenkrog B, Martinet W, Vervenne H, Ververs EJ, Larsson L, Van den Berghe G: Early parenteral nutrition evokes a phenotype of autophagy deficiency in liver and skeletal muscle of critically ill rabbits. Endocrinology 2012, 153:2267-2276.
15. Choi AJ, Ryter SW: Autophagy in inflammatory diseases. Int J cell biol 2011, 2011:732798.
16. van Schijndel RJM S, Weijs PJM, Sauerwein HP, de Groot SDW, Beishuizen A, Girbes ARJ: An algorithm for balanced protein/energy provision in critically ill mechanically ventilated patients. e-SPEN, Eur e-J Clin Nut Metab 2007, 2:69-74.
17. Singer P, Berger MM, Van den Berghe G, Biolo G, Calder P, Forbes A, Griffiths R, Kreyman G, Leverve X, Pichard C, ESPEN: ESPEN Guidelines on Parenteral Nutrition: intensive care. Clin Nutr 2009, 28:387-400.
18. Compher C, Frankenfield D, Keim N, Roth-Yousey L: Best practice methods to apply to measurement of resting metabolic rate in adults: a systematic review. J Am Diet Assoc 2006, 106:881-903.
19. Weijs PJM, Sauerwein HP, Kondrup J: Protein recommendations in the ICU: g protein/kg body weight - which body weight for underweight and obese patients? Clin Nutr 2012, 31:774-775.
20. van Schijndel RJMS, de Groot SDW, Driessen RH, Ligthart-Melis G, Girbes ARJ, Beishuizen A, Weijs PJM: Computer-aided support improves early and adequate delivery of nutrients in the ICU. Neth J Med 2009, 67:388-393.
21. Dellinger RP, Carlet JM, Masur H, Gerlach H, Calandra T, Cohen J, Gea-Banacloche J, Keh D, Marshall JC, Parker MM, Ramsay G, Zimmerman JL, Vincent JL, Levy MM: Surviving Sepsis Campaign guidelines for management of severe sepsis and septic shock. Critical care medicine 2004, 32:858-873.
22. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL: Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. Intensive care medicine 2008, 34:17-60.
23. Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger D, Reggiani C, Schiaffino S, Sandri M: Autophagy is required to maintain muscle mass. Cell Metab 2009, 10:507-515.
24. Hermans G, Casaer MP, Clerckx B, Guiza F, Vanhullebusch T, Derde S, Meersseman P, Derese I, Mesotten D, Wouters PJ, Van Cromphaut S, Debaveye Y, Gosselink R, Gunst J, Wilmer A, Van den Berghe G, Vanhorebeek I: Effect of tolerating macronutrient deficit on the development of intensive-care unit acquired weakness: a subanalysis of the EPaNIC trial. The lancet Respiratory medicine 2013, 1:621-629.
25. Virgin HW, Levine B: Autophagy genes in immunity. Nat Immunol 2009, 10:461-470.
26. Klaude M, Mori M, Tjader I, Gustafsson T, Wernerman J, Rooyackers O: Protein metabolism and gene expression in skeletal muscle of critically ill patients with sepsis. Clin Sci(Lond) 2012, 122:133-142.
27. Heidegger CP, Berger MM, Graf S, Zingg W, Darmon P, Costanza MC, Thibault R, Pichard C: Optimisation of energy provision with supplemental parenteral nutrition in critically ill patients: a randomised controlled clinical trial. Lancet 2013, 381:385-393.
28. Savard JF, Faisy C, Lerolle N, Guerot E, Diehl JL, Fagon JY: Validation of a predictive method for an accurate assessment of resting energy expenditure in medical mechanically ventilated patients. Crit Care Med 2008, 36:1175-1183.
29. Faisy C, Guerot E, Diehl JL, Labrousse J, Fagon JY: Assessment of resting energy expenditure in mechanically ventilated patients. Am J Clin Nutr 2003, 78:241-249.
30. Frankenfield D, Smith JS, Cooney RN: Validation of 2 approaches to predicting resting metabolic rate in critically ill patients. JPEN J Parenter Enteral Nutr 2004, 28:259-264.
31. Singer P, Anbar R, Cohen J, Shapiro H, Shalita-Chesner M, Lev S, Grozovski E, Theilla M, Frishman S, Madar Z: The tight calorie control study (TICACOS): a prospective, randomized, controlled pilot study of nutritional support in critically ill patients. Intensive Care Med 2011, 37:601-609.
32. Weijs PJM, Wischmeyer PE: Optimizing energy and protein balance in the ICU. Curr Opin Clin Nutr Metab Care 2013, 16:194-201.