Effects of clofazimine on planktonic and biofilm growth of Mycobacterium tuberculosis and Mycobacterium smegmatis

Journal of Global Antimicrobial Resistance

Volumn 3, Issue 1, 2015, Pages 13-18

  Mothiba, Maborwa T ^a   Anderson, Ronald ^a   Fourie, Bernard ^a   Germishuizen, Willem A ^a   Cholo, Moloko C ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Biofilm; Clofazimine; Minimum bactericidal concentration; Mycobacterium smegmatis; Mycobacterium tuberculosis; Planktonic

Indexed keywords

CLOFAZIMINE;

ARTICLE; BACTERIAL GROWTH; BACTERICIDAL ACTIVITY; BIOFILM; CONTROLLED STUDY; CULTURAL ANTHROPOLOGY; DILUTION; MINIMUM BACTERICIDAL CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLANKTON; PRIORITY JOURNAL;

BACILLI (CLASS); CORYNEBACTERINEAE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

EID: 84924168937     PISSN: 22137165     EISSN: 22137173     Source Type: Journal    
DOI: 10.1016/j.jgar.2014.12.001     Document Type: Article

References (30)

1. A.K. Ojha, A.D. Baughn, D. Sambandon, T. Hsu, X. Trivelli, and Y. Guerardel Growth of Mycobacterium tuberculosis biofilms containing free mycolic acids and harbouring drug-tolerant bacteria Mol Microbiol 69 2008 164 174
2. A.K. Ojha, X. Thivelli, Y. Guerardel, L. Kremer, and G.F. Hatfull Enzymatic hydrolysis of trehalose dimycolate releases free mycolic acids during mycobacterial growth in biofilms J Biol Chem 285 2010 17380 17389
3. J.M. Pang, E. Layre, L. Sweet, A. Sherrid, D.B. Moody, and A. Ojha The polyketide Pks1 contributes to biofilm formation in Mycobacterium tuberculosis J Bacteriol 194 2012 715 721
4. M. McNabe, R. Tennant, L. Danelishvili, L. Young, and L.E. Bermidez Mycobacterium avium ssp. hominissius biofilm is composed of distinct phenotypes and influenced by the presence of antimicrobials Clin Microbiol Infect 17 2011 697 703
5. M.S. Islam, J.P. Richards, and A.K. Ojha Targeting drug tolerance in mycobacteria: a perspective from mycobacterial biofilms Expert Rev Anti Infect Ther 10 2012 1055 1066
6. B.M. Saunders, and A.M. Cooper Restraining mycobacteria: role of granuloma in mycobacterial infections Immunol Cell Biol 78 2000 334 341
7. A.J. Lenaerts, D. Hoff, S. Aly, S. Ehlers, K. Andries, and L. Cantarero Location of persisting mycobacteria in a guinea pig model of tuberculosis revealed by r207910 Antimicrob Agents Chemother 51 2007 3338 3345
8. J. Harper, C. Skerry, S.L. Davis, R. Tasneen, M. Weir, and I. Kramnik Mouse model of necrotic tuberculosis granulomas develops hypoxic lesions J Infect Dis 205 2012 595 602
9. C. Feldman, and R. Anderson Antibiotic resistance of pathogens causing community-acquired pneumonia Semin Respir Crit Care Med 33 2012 232 243
10. N. Beckloff, D. Laube, T. Castro, D. Furgang, S. Park, and D. Perlin Activity of an antimicrobial peptide mimetic against planktonic and biofilm cultures of oral pathogens Antimicrob Agents Chemother 51 2007 4125 4132
11. B. Findlay, G.G. Zhanel, and F. Schweizer Cationic amphiphiles, a new generation of antimicrobials inspired by the natural antimicrobial peptide scaffold Antimicrob Agents Chemother 54 2010 4049 4058
12. M.C. Cholo, H.C. Steel, P.B. Fourie, W.A. Germishuizen, and R. Anderson Clofazimine: current status and future prospects J Antimicrob Chemother 67 2012 290 298
13. K.E. Dooley, E.A. Obuku, N. Durakovic, V. Belitsky, C. Mitnick, and E.L. Nuermberger World Health Organization group 5 drugs for the treatment of drug-resistant tuberculosis: unclear efficacy or untapped potential? J Infect Dis 207 2013 1352 1358
14. A. Van Deun, A.K. Maug, M.A. Salim, P.K. Das, M.R. Sarker, and P. Daru Short, highly effective and inexpensive standardized treatment of multidrug-resistant tuberculosis Am J Respir Crit Care Med 182 2010 684 692
15. S.H. Cho, S. Warit, B. Wan, C.H. Hwang, G.F. Pauli, and S.G. Franzblau Low-oxygen-recovery assay for high-throughput screening of compounds against nonreplicating Mycobacterium tuberculosis Antimicrob Agents Chemother 51 2007 1380 1385
16. S. Grant, B.B. Kaufmann, N.S. Chand, N. Haseley, and D.T. Hung Eradication of bacterial persisters with antibiotic-generated hydroxyl radicals Proc Natl Acad Sci U S A 109 2012 12147 12152
17. J.H. Grosset, T.G. Singer, and W.R. Bishai New drugs for the treatment of tuberculosis: hope and reality Int J Tuberc Lung Dis 16 2012 1005 1014
18. J. Xu, Y. Lu, L. Fu, H. Zhu, B. Wang, and K. Mdluli In vitro and in vivo activity of clofazimine against Mycobacterium tuberculosis persisters Int J Tuberc Lung Dis 16 2012 1119 1125
19. M.C. Cholo, H.I. Boshoff, H.C. Steel, R. Cockeran, N.M. Matlola, and K.J. Downing Effects of clofazimine on potassium uptake by a Trk-deletion mutant of Mycobacterium tuberculosis J Antimicrob Chemother 57 2006 79 84
20. L.B. Heifets, and P.J. Lindholm-Levy Bacteriostatic and bactericidal activity of ciprofloxacin and ofloxacin against Mycobacterium tuberculosis and Mycobacterium avium complex Tubercle 68 1987 267 276
21. G.A. O'Toole Microtiter dish biofilm formation assay J Vis Exp 47 2011 2437
22. K. Kulka, G. Hatfull, and A.K. Ojha Growth of Mycobacterium tuberculosis biofilms J Vis Exp 60 2012 3820
23. S.I. Stepanovic, L.R. Cirkovic, and M. Svabic-Vlahovic Biofilm formation by Salmonella spp. and Listeria monocytogenes on plastic surface Lett Appl Microbiol 38 2004 428 432
24. S.M. Irwin, V. Gruppo, E. Brooks, J. Gilliland, M. Scherman, and M.J. Reichlen Limited activity of clofazimine as a single drug in a mouse model of tuberculosis exhibiting caseous necrotic granulomas Antimicrob Agents Chemother 58 2014 4026 4034
25. T. Yano, S. Kassovska-Bratinova, J.S. Teh, J. Winkler, K. Sullivan, and A. Isaacs Reduction of clofazimine by mycobacterial type 2 NADH:quinone oxidoreductase: a pathway for the generation of bactericidal levels of reactive oxygen species J Biol Chem 286 2011 10276 10287
26. E.W. Orenstein, S. Basu, N.S. Shah, J.R. Andrews, G.H. Friedland, and A.P. Moll Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis Lancet Infect Dis 9 2009 153 161
27. T. Dey, G. Brigden, H. Cox, Z. Shubber, G. Cooke, and N. Ford Outcomes of clofazimine for the treatment of drug-resistant tuberculosis: a systematic review and meta-analysis J Antimicrob Chemother 68 2013 284 293
28. M. Gopal, N. Padayatchi, J.Z. Metcalfe, and M.R. O'Donnell Systematic review of clofazimine for the treatment of drug-resistant tuberculosis Int J Tuberc Lung Dis 17 2013 1001 1007
29. T.S. Shim, and K.-W. Jo Medical treatment of pulmonary multidrug-resistant tuberculosis Infect Chemother 45 2013 367 374
30. J.H. Grosset, S. Tyagi, D.V. Almeida, P.J. Converse, S.Y. Li, and N.C. Ammerman Assessment of clofazimine activity in a second-line regimen for tuberculosis in mice Am J Respir Crit Care Med 188 2013 608 612