Increased susceptibility of dyslipidemic LSR+/- mice to amyloid stress is associated with changes in cortical cholesterol levels

Journal of Alzheimer's Disease

Volumn 45, Issue 1, 2015, Pages 195-204

  Pinçon, Anthony ^a,b   Thomas, Melanie H ^a,b   Huguet, Marion ^a,b   Allouche, Ahmad ^a,b,d   Colin, Julie C ^a,b   Georges, Alain ^a   Derrien, Annabelle ^a,b   Lanhers, Marie Claire ^a,b   Malaplate Armand, Catherine ^a,b,c   Oster, Thierry ^a,b   Corbier, Catherine ^a,b   Pillot, Thierry ^d,e   Olivier, Jean Luc ^a,b,c   Yen, Frances T ^a,b,d  

^a UNIVERSITÉ DE LORRAINE   (France)

^b CEMAGREF   (France)

^c UNIVERSITY HOSPITAL OF NANCY   (France)

^d INSERM   (France)

^e Synaging SAS   (France)

Author keywords

Alzheimer's disease; amyloid oligomers; animal model; cholesterol; cognitive impairment; learning; lipolysis stimulated lipoprotein receptor; memory

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; CHOLESTEROL; LIPOPROTEIN RECEPTOR; OLIGOMER; POSTSYNAPTIC DENSITY PROTEIN 95; SYNAPTOSOMAL ASSOCIATED PROTEIN 25; 24-HYDROXYCHOLESTEROL; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); ANGULIN-1 PROTEIN, MOUSE; CHOLESTEROL DERIVATIVE; DLGH4 PROTEIN, MOUSE; GUANYLATE KINASE; MEMBRANE PROTEIN; MESSENGER RNA; PEPTIDE FRAGMENT; SNAP25 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN CORTEX; COGNITIVE DEFECT; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DYSLIPIDEMIA; FEMALE; GENOTYPE; HIPPOCAMPUS; LATENT PERIOD; LEARNING; LIPID HOMEOSTASIS; LONG TERM MEMORY; MALE; METABOLITE; MORRIS WATER MAZE TEST; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; SHORT TERM MEMORY; ANALYSIS OF VARIANCE; ANIMAL; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MAZE TEST; METABOLISM; PHYSIOLOGY; REGRESSION ANALYSIS; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; ANALYSIS OF VARIANCE; ANIMALS; CEREBRAL CORTEX; CHOLESTEROL; GENE EXPRESSION REGULATION; GUANYLATE KINASE; HIPPOCAMPUS; HYDROXYCHOLESTEROLS; MAZE LEARNING; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; PEPTIDE FRAGMENTS; RECEPTORS, LIPOPROTEIN; REGRESSION ANALYSIS; RNA, MESSENGER; SYNAPTOSOMAL-ASSOCIATED PROTEIN 25;

EID: 84924162707     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-142127     Document Type: Article

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