The role of ubiquitin/Nedd4-2 in the pathogenesis of mesial temporal lobe epilepsy

Physiology and Behavior

Volumn 143, Issue , 2015, Pages 104-112

  Wu, Liwen ^a   Peng, Jing ^a   Kong, Huimin ^a   Yang, Ping ^a   He, Fang ^a   Deng, Xiaolu ^a   Gan, Na ^a   Yin, Fei ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

Author keywords

Mesial temporal lobe epilepsy; Nedd4 2; Ubiquitin; Ubiquitin proteasome system

Indexed keywords

ALPHA EPITHELIAL SODIUM CHANNEL; EPITHELIAL SODIUM CHANNEL; PROTEASOME; UBIQUITIN; UBIQUITIN PROTEIN LIGASE NEDD4; UBIQUITIN PROTEIN LIGASE NEDD4-2; UNCLASSIFIED DRUG; ADENOSINE PHOSPHATE; BENZYLOXYCARBONYLLEUCYL-LEUCYL-LEUCINE ALDEHYDE; CYSTEINE PROTEINASE INHIBITOR; ESCRT PROTEIN; LEUPEPTIN; LITHIUM CHLORIDE; MUSCARINIC AGENT; NEDD4 UBIQUITIN PROTEIN LIGASES; PILOCARPINE; SMALL INTERFERING RNA; TRANQUILIZER; UBIQUITIN ADENYLATE; UBIQUITIN PROTEIN LIGASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EPILEPTOGENESIS; HIPPOCAMPAL NEURONAL CULTURE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MESIAL TEMPORAL LOBE EPILEPSY; MOSSY FIBER; NERVE CELL; NERVE SPROUTING; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE; WESTERN BLOTTING; ANALYSIS OF VARIANCE; ANIMAL; CELL CULTURE; CHEMICALLY INDUCED; CYTOLOGY; DISEASE MODEL; DRUG EFFECTS; EPILEPSY, TEMPORAL LOBE; FEMALE; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; HIPPOCAMPUS; MALE; METABOLISM; NEWBORN; PHYSIOLOGY; SPRAGUE DAWLEY RAT; TIME;

ADENOSINE MONOPHOSPHATE; ANALYSIS OF VARIANCE; ANIMALS; ANIMALS, NEWBORN; ANTIMANIC AGENTS; CELLS, CULTURED; CYSTEINE PROTEINASE INHIBITORS; DISEASE MODELS, ANIMAL; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; EPILEPSY, TEMPORAL LOBE; FEMALE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; IMMUNOPRECIPITATION; LEUPEPTINS; LITHIUM CHLORIDE; MALE; MUSCARINIC AGONISTS; NEURONS; PILOCARPINE; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; TIME FACTORS; TRANSFECTION; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES; UBIQUITINS;

EID: 84924132861     PISSN: 00319384     EISSN: 1873507X     Source Type: Journal    
DOI: 10.1016/j.physbeh.2015.02.026     Document Type: Article

References (23)

1. Wu L., Peng J., Wei C., Liu G., Wang G., Li K., Yin F. Characterization, using comparative proteomics, of differentially expressed proteins in the hippocampus of the mesial temporal lobe of epileptic rats following treatment with valproate. Amino Acids 2011, 40(1):221-238.
2. Thom M. Review: Hippocampal sclerosis in epilepsy: a neuropathology review. Neuropathol Appl Neurobiol. 2014, 40(5):520-543.
3. Cendes F., Sakamoto A.C., Spreafico R., Bingaman W., Becker A.J. Epilepsies associated with hippocampal sclerosis. Acta Neuropathol 2014, 128(1):21-37.
4. Aghdam S.Y., Sheibani N. The ubiquitin-proteasome system and microvascular complications of diabetes. J. Ophthalmic Vis. Res. 2013, 8(3):244-256.
5. Zemeckiene Z., Vitkauskiene A., Sjakste T., Sitkauskiene B., Sakalauskas R. Proteasomes and proteasomal gene polymorphism in association with inflammation and various diseases. Medicina (Kaunas) 2013, 49(5):207-213.
6. Garyali P., Siwach P., Singh P.K., Puri R., Mittal S., Sengupta S., Parihar R., Ganesh S. The malin-laforin complex suppresses the cellular toxicity of misfolded proteins by promoting their degradation through the ubiquitin-proteasome system. Hum. Mol. Genet. 2009, 18(4):688-700.
7. Shen M., Schmitt S., Buac D., Dou Q.P. Targeting the ubiquitin-proteasome system for cancer therapy. Expert Opin. Ther. Targets 2013, 17(9):1091-1108.
8. Wu L., Zhang C., Yin F. Dynamic changes in the proteomic profile of mesial temporal lobe epilepsy at different disease stages in an immature rat model. Protein Pept. Lett. Oct. 2015, 22(2):180-192.
9. Rotin D., Staub O. Nedd4-2 and the regulation of epithelial sodium transport. Front. Physiol. 2012, 3:212.
10. Laedermann C.J., Cachemaille M., Kirschmann G., Pertin M., Gosselin R.D., Chang I., Albesa M., Towne C., Schneider B.L., Kellenberger S., Abriel H., Decosterd I. Dysregulation of voltage-gated sodium channels by ubiquitin ligase NEDD4-2 in neuropathic pain. J. Clin. Invest. 2013, 123(7):3002-3013.
11. Fotia A.B., Ekberg J., Adams D.J., Cook D.I., Poronnik P., Kumar S. Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2. J. Biol. Chem. 2004, 279(28):28930-28935.
12. Bongiorno D., Schuetz F., Poronnik P., Adams D.J. Regulation of voltage-gated ion channels in excitable cells by the ubiquitin ligases Nedd4 and Nedd4-2. Channels (Austin) 2011, 5(1):79-88.
13. Blair R.E., Deshpande L.S., Sombati S., Falenski K.W., Martin B.R., DeLorenzo R.J. Activation of the cannabinoid type-1 receptor mediates the anticonvulsant properties of cannabinoids in the hippocampal neuronal culture models of acquired epilepsy and status epilepticus. J. Pharmacol. Exp. Ther. 2006, 317(3):1072-1078.
14. Girard J.M., Turnbull J., Ramachandran N., Minassian B.A. Progressive myoclonus epilepsy. Handb. Clin. Neurol. 2013, 113:1731-1736.
15. He P.X., Tang Y.L., Cai W.L., Huang Y.H., Fang C., Jing H.L. Morphology changes of ubiquitin-proteasome system in traumatic epilepsy. Fa Yi Xue Za Zhi 2010, 26(1):10-14.
16. Kowalski J.R., Dube H., Touroutine D., Rush K.M., Goodwin P.R., Carozza M., Didier Z., Francis M.M., Juo P. The anaphase-promoting complex (APC) ubiquitin ligase regulates GABA transmission at the C. elegans neuromuscular junction. Mol. Cell. Neurosci. 2014, 58:62-75.
17. Kuo C.T., Zhu S., Younger S., Jan L.Y., Jan Y.N. Identification of E2/E3 ubiquitinating enzymes and caspase activity regulating Drosophila sensory neuron dendrite pruning. Neuron 2006, 51(3):283-290.
18. Stone S.L. The role of ubiquitin and the 26S proteasome in plant abiotic stress signaling. Front. Plant Sci. 2014, 5:135.
19. Dibbens L.M., Ekberg J., Taylor I., Hodgson B.L., Conroy S.J., Lensink I.L., Kumar S., Zielinski M.A., Harkin L.A., Sutherland G.R., Adams D.J., Berkovic S.F., Scheffer I.E., Mulley J.C., Poronnik P. NEDD4-2 as a potential candidate susceptibility gene for epileptic photosensitivity. Genes Brain Behav. 2007, 6(8):750-755.
20. Rotin D., Staub O. Nedd4-2 and the regulation of epithelial sodium transport. Front. Physiol. 2012, 3:212.
21. Laedermann C.J., Decosterd I., Abriel H. Ubiquitylation of voltage-gated sodium channels. Handb. Exp. Pharmacol. 2014, 221:231-250.
22. Rotin D., Staub O. Role of the ubiquitin system in regulating ion transport. Pflugers Arch. 2011, 461(1):1-21.
23. Hryciw D.H., Ekberg J., Lee A., Lensink I.L., Kumar S., Guggino W.B., Cook D.I., Pollock C.A., Poronnik P. Nedd4-2 functionally interacts with ClC-5: involvement in constitutive albumin endocytosis in proximal tubule cells. J. Biol. Chem. 2004, 279(53):54996-55007.