Dysregulation of transition metal ion homeostasis is the molecular basis for cadmium toxicity in Streptococcus pneumoniae

Nature Communications

Volumn 6, Issue , 2015, Pages

  Begg, Stephanie L ^a   Eijkelkamp, Bart A ^a   Luo, Zhenyao ^b   Couñago, Rafael M ^b   Morey, Jacqueline R ^a   Maher, Megan J ^c   Ong, Cheryl Lynn Y ^b   McEwan, Alastair G ^b   Kobe, Bostjan ^b   O'Mara, Megan L ^b   Paton, James C ^a   McDevitt, Christopher A ^a  

^a UNIVERSITY OF ADELAIDE   (Australia)

^b UNIVERSITY OF QUEENSLAND   (Australia)

^c LA TROBE UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; GLUTATHIONE; MANGANESE; PERMEASE; ZINC; ADHESIN; LIPOPROTEIN; MAGNESIUM; PSAA PROTEIN, STREPTOCOCCUS;

BACTERIUM; BIOACCUMULATION; BIOCHEMICAL COMPOSITION; BIOLOGICAL UPTAKE; CADMIUM; HOMEOSTASIS; TOXICITY;

ARTICLE; BACTERIAL GROWTH; CHEMICAL STRUCTURE; CONTROLLED STUDY; EFFUSION; HOMEOSTASIS; IN VITRO STUDY; IN VIVO STUDY; METAL BINDING; NONHUMAN; OXIDATIVE STRESS; STREPTOCOCCUS PNEUMONIAE; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION; CHEMISTRY; CRYSTALLIZATION; DRUG EFFECTS; IMMUNOBLOTTING; METABOLISM; MOLECULAR MODEL; PHYSIOLOGY; PROTEIN CONFORMATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

PROKARYOTA; STREPTOCOCCUS PNEUMONIAE;

ADHESINS, BACTERIAL; CADMIUM; CRYSTALLIZATION; HOMEOSTASIS; IMMUNOBLOTTING; LIPOPROTEINS; MAGNESIUM; MODELS, MOLECULAR; OXIDATIVE STRESS; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; STREPTOCOCCUS PNEUMONIAE; ZINC;

EID: 84924118265     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms7418     Document Type: Article

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