-
2
-
-
0020455057
-
Thick ascending limb of Henle's loop
-
Burg MB. Thick ascending limb of Henle's loop. Kidney Int 22: 454-464, 1982.
-
(1982)
Kidney Int
, vol.22
, pp. 454-464
-
-
Burg, M.B.1
-
3
-
-
77953673284
-
SPAKling insight into blood pressure regulation
-
Castañeda-Bueno M, Gamba G. SPAKling insight into blood pressure regulation. EMBO Mol Med 2: 39-41, 2010.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 39-41
-
-
Castañeda-Bueno, M.1
Gamba, G.2
-
4
-
-
84858184957
-
Prenatal programming of rat cortical collecting tubule sodium transport
-
Cheng CJ, Lozano G, Baum M. Prenatal programming of rat cortical collecting tubule sodium transport. Am J Physiol Renal Physiol 302: F674-F678, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.302
, pp. F674-F678
-
-
Cheng, C.J.1
Lozano, G.2
Baum, M.3
-
5
-
-
84865735283
-
Kidney-specific WNK1 inhibits sodium reabsorption in the cortical thick ascending limb
-
Cheng CJ, Truong T, Baum M, Huang CL. Kidney-specific WNK1 inhibits sodium reabsorption in the cortical thick ascending limb. Am J Physiol Renal Physiol 303: F667-F673, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
, pp. F667-F673
-
-
Cheng, C.J.1
Truong, T.2
Baum, M.3
Huang, C.L.4
-
6
-
-
0042847432
-
PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1)
-
Dowd BF, Forbush B. PASK (proline-alanine-rich STE20-related kinase), a regulatory kinase of the Na-K-Cl cotransporter (NKCC1). J Biol Chem 278: 27347-27353, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 27347-27353
-
-
Dowd, B.F.1
Forbush, B.2
-
7
-
-
84868307684
-
SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner
-
Grimm PR, Taneja TK, Liu J, Coleman R, Chen YY, Delpire E, Wade JB, Welling PA. SPAK isoforms and OSR1 regulate sodium-chloride co-transporters in a nephron-specific manner. J Biol Chem 287: 37673- 37690, 2012.
-
(2012)
J Biol Chem
, vol.287
, pp. 37673-37690
-
-
Grimm, P.R.1
Taneja, T.K.2
Liu, J.3
Coleman, R.4
Chen, Y.Y.5
Delpire, E.6
Wade, J.B.7
Welling, P.A.8
-
8
-
-
77957272228
-
Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells
-
Gunaratne R, Braucht DW, Rinschen MM, Chou CL, Hoffert JD, Pisitkun T, Knepper MA. Quantitative phosphoproteomic analysis reveals cAMP/vasopressin-dependent signaling pathways in native renal thick ascending limb cells. Proc Natl Acad Sci USA 107: 15653-15658, 2010.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 15653-15658
-
-
Gunaratne, R.1
Braucht, D.W.2
Rinschen, M.M.3
Chou, C.L.4
Hoffert, J.D.5
Pisitkun, T.6
Knepper, M.A.7
-
9
-
-
79953043089
-
Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells
-
Hannemann A, Flatman PW. Phosphorylation and transport in the Na-K-2Cl cotransporters, NKCC1 and NKCC2A, compared in HEK-293 cells. PLos One 6: e17992, 2011.
-
(2011)
PLos One
, vol.6
-
-
Hannemann, A.1
Flatman, P.W.2
-
10
-
-
0032890810
-
Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop
-
Kim GH, Ecelbarger CA, Mitchell C, Packer RK, Wade JB, Knepper MA. Vasopressin increases Na-K-2Cl cotransporter expression in thick ascending limb of Henle's loop. Am J Physiol Renal Physiol 276: F96- F103, 1999.
-
(1999)
Am J Physiol Renal Physiol
, vol.276
, pp. F96-F103
-
-
Kim, G.H.1
Ecelbarger, C.A.2
Mitchell, C.3
Packer, R.K.4
Wade, J.B.5
Knepper, M.A.6
-
11
-
-
84908093597
-
Short forms of Ste20-related proline/alanine-rich kinase (SPAK) in the kidney are created by aspartyl aminopeptidase (Dnpep)- mediated proteolytic cleavage
-
Markadieu N, Rios K, Spiller BW, McDonald WH, Welling PA, Delpire E. Short forms of Ste20-related proline/alanine-rich kinase (SPAK) in the kidney are created by aspartyl aminopeptidase (Dnpep)- mediated proteolytic cleavage. J Biol Chem 289: 29273-29284, 2014.
-
(2014)
J Biol Chem
, vol.289
, pp. 29273-29284
-
-
Markadieu, N.1
Rios, K.2
Spiller, B.W.3
McDonald, W.H.4
Welling, P.A.5
Delpire, E.6
-
12
-
-
80052705787
-
A SPAK isoform switch modulates renal salt transport and blood pressure
-
McCormick JA, Mutig K, Nelson JH, Saritas T, Hoorn EJ, Yang CL, Rogers S, Curry J, Delpire E, Bachmann S, Ellison DH. A SPAK isoform switch modulates renal salt transport and blood pressure. Cell Metab 14: 352-364, 2011.
-
(2011)
Cell Metab
, vol.14
, pp. 352-364
-
-
McCormick, J.A.1
Mutig, K.2
Nelson, J.H.3
Saritas, T.4
Hoorn, E.J.5
Yang, C.L.6
Rogers, S.7
Curry, J.8
Delpire, E.9
Bachmann, S.10
Ellison, D.H.11
-
13
-
-
80051782146
-
Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters
-
Mercier-Zuber A, O'Shaughnessy KM. Role of SPAK and OSR1 signalling in the regulation of NaCl cotransporters. Curr Opin Nephrol Hypertens 20: 534-540, 2011.
-
(2011)
Curr Opin Nephrol Hypertens
, vol.20
, pp. 534-540
-
-
Mercier-Zuber, A.1
O'Shaughnessy, K.M.2
-
14
-
-
30044442784
-
WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1
-
Moriguchi T, Urushiyama S, Hisamoto N, Iemura S, Uchida S, Natsume T, Matsumoto K, Shibuya H. WNK1 regulates phosphorylation of cation-chloride-coupled cotransporters via the STE20-related kinases, SPAK and OSR1. J Biol Chem 280: 42685-42693, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 42685-42693
-
-
Moriguchi, T.1
Urushiyama, S.2
Hisamoto, N.3
Iemura, S.4
Uchida, S.5
Natsume, T.6
Matsumoto, K.7
Shibuya, H.8
-
15
-
-
84881656657
-
+ transporters along nephron during ANG II-dependent hypertension: Distal stimulation counteracted by proximal inhibition
-
+ transporters along nephron during ANG II-dependent hypertension: distal stimulation counteracted by proximal inhibition. Am J Physiol Renal Physiol 305: F510-F519, 2013.
-
(2013)
Am J Physiol Renal Physiol
, vol.305
, pp. F510-F519
-
-
Nguyen, M.T.1
Lee, D.H.2
Delpire, E.3
McDonough, A.A.4
-
16
-
-
84863309621
-
+, and H2O transporters' abundance along the nephron
-
+, and H2O transporters' abundance along the nephron. Am J Physiol Renal Physiol 303: F92-F104, 2012.
-
(2012)
Am J Physiol Renal Physiol
, vol.303
, pp. F92-F104
-
-
Nguyen, M.T.1
Yang, L.E.2
Fletcher, N.K.3
Lee, D.H.4
Kocinsky, H.5
Bachmann, S.6
Delpire, E.7
McDonough, A.A.8
-
17
-
-
17344392308
-
A new mathematical model for relative quantification in real-time RT-PCR
-
Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: 2002-2007, 2001.
-
(2001)
Nucleic Acids Res
, vol.29
, pp. 2002-2007
-
-
Pfaffl, M.W.1
-
18
-
-
0346101747
-
- cotransporter in the nervous system: Evidence for a scaffolding role of the kinase
-
- cotransporter in the nervous system: evidence for a scaffolding role of the kinase. J Biol Chem 278: 52848-52856, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 52848-52856
-
-
Piechotta, K.1
Garbarini, N.2
England, R.3
Delpire, E.4
-
19
-
-
0037184942
-
Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1)
-
Piechotta K, Lu J, Delpire E. Cation chloride cotransporters interact with the stress-related kinases Ste20-related proline-alanine-rich kinase (SPAK) and oxidative stress response 1 (OSR1). J Biol Chem 277: 50812-50819, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 50812-50819
-
-
Piechotta, K.1
Lu, J.2
Delpire, E.3
-
20
-
-
0032896762
-
Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP
-
Plata C, Mount DB, Rubio V, Hebert SC, Gamba G. Isoforms of the Na-K-2Cl cotransporter in murine TAL II. Functional characterization and activation by cAMP. Am J Physiol Renal Physiol 276: F359-F366, 1999.
-
(1999)
Am J Physiol Renal Physiol
, vol.276
, pp. F359-F366
-
-
Plata, C.1
Mount, D.B.2
Rubio, V.3
Hebert, S.C.4
Gamba, G.5
-
21
-
-
77953459148
-
Role of the WNKactivated SPAK kinase in regulating blood pressure
-
Rafiqi FH, Zuber AM, Glover M, Richardson C, Fleming S, Jovanović S, Jovanović A, O'Shaughnessy KM, Alessi DR. Role of the WNKactivated SPAK kinase in regulating blood pressure. EMBO Mol Med 2: 63-75, 2010.
-
(2010)
EMBO Mol Med
, vol.2
, pp. 63-75
-
-
Rafiqi, F.H.1
Zuber, A.M.2
Glover, M.3
Richardson, C.4
Fleming, S.5
Jovanović, S.6
Jovanović, A.7
O'Shaughnessy, K.M.8
Alessi, D.R.9
-
22
-
-
77953446507
-
- cotransporter 2
-
- cotransporter 2. Mol Cell Biol 30: 3027-3037, 2010.
-
(2010)
Mol Cell Biol
, vol.30
, pp. 3027-3037
-
-
Reiche, J.1
Theilig, F.2
Rafiqi, F.H.3
Carlo, A.S.4
Militz, D.5
Mutig, K.6
Todiras, M.7
Christensen, E.I.8
Ellison, D.H.9
Bader, M.10
Nykjaer, A.11
Bachmann, S.12
Alessi, D.13
Willnow, T.E.14
-
23
-
-
79952798017
-
Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways
-
Richardson C, Sakamoto K, de los Heros P, Deak M, Campbell DG, Prescott AR, Alessi DR. Regulation of the NKCC2 ion cotransporter by SPAK-OSR1-dependent and -independent pathways. J Cell Sci 124: 789-800, 2011.
-
(2011)
J Cell Sci
, vol.124
, pp. 789-800
-
-
Richardson, C.1
Sakamoto, K.2
de los Heros, P.3
Deak, M.4
Campbell, D.G.5
Prescott, A.R.6
Alessi, D.R.7
-
24
-
-
84874621317
-
SPAK differentially mediates vasopressin effects on sodium cotransporters
-
Saritas T, Borschewski A, McCormick JA, Paliege A, Dathe C, Uchida S, Terker A, Himmerkus N, Bleich M, Demaretz S, Laghmani K, Delpire E, Ellison DH, Bachmann S, Mutig K. SPAK differentially mediates vasopressin effects on sodium cotransporters. J Am Soc Nephrol 24: 407-418, 2013.
-
(2013)
J Am Soc Nephrol
, vol.24
, pp. 407-418
-
-
Saritas, T.1
Borschewski, A.2
McCormick, J.A.3
Paliege, A.4
Dathe, C.5
Uchida, S.6
Terker, A.7
Himmerkus, N.8
Bleich, M.9
Demaretz, S.10
Laghmani, K.11
Delpire, E.12
Ellison, D.H.13
Bachmann, S.14
Mutig, K.15
-
25
-
-
0033045705
-
Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3
-
Tamari M, Daigo Y, Nakamura Y. Isolation and characterization of a novel serine threonine kinase gene on chromosome 3p22-21.3. J Hum Genet 44: 116-120, 1999.
-
(1999)
J Hum Genet
, vol.44
, pp. 116-120
-
-
Tamari, M.1
Daigo, Y.2
Nakamura, Y.3
-
26
-
-
0032528534
-
Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia
-
Ushiro H, Tsutsumi T, Suzuki K, Kayahara T, Nakano K. Molecular cloning and characterization of a novel Ste20-related protein kinase enriched in neurons and transporting epithelia. Arch Biochem Biophys 355: 233-240, 1998.
-
(1998)
Arch Biochem Biophys
, vol.355
, pp. 233-240
-
-
Ushiro, H.1
Tsutsumi, T.2
Suzuki, K.3
Kayahara, T.4
Nakano, K.5
-
27
-
-
26844532768
-
The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases
-
Vitari AC, Deak M, Morrice NA, Alessi DR. The WNK1 and WNK4 protein kinases that are mutated in Gordon's hypertension syndrome phosphorylate and activate SPAK and OSR1 protein kinases. Biochem J 391: 17-24, 2005.
-
(2005)
Biochem J
, vol.391
, pp. 17-24
-
-
Vitari, A.C.1
Deak, M.2
Morrice, N.A.3
Alessi, D.R.4
-
28
-
-
58549108489
-
From the cover: Whole-genome association study identifies STK39 as a hypertension susceptibility gene
-
Wang Y, O'Connell JR, McArdle PF, Wade JB, Dorff SE, Shah SJ, Shi X, Pan L, Rampersaud E, Shen H, Kim JD, Subramanya AR, Steinle NI, Parsa A, Ober CC, Welling PA, Chakravarti A, Weder AB, Cooper RS, Mitchell BD, Shuldiner AR, Chang YP. From the cover: whole-genome association study identifies STK39 as a hypertension susceptibility gene. Proc Natl Acad Sci USA 106: 226-231, 2009.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 226-231
-
-
Wang, Y.1
O'Connell, J.R.2
McArdle, P.F.3
Wade, J.B.4
Dorff, S.E.5
Shah, S.J.6
Shi, X.7
Pan, L.8
Rampersaud, E.9
Shen, H.10
Kim, J.D.11
Subramanya, A.R.12
Steinle, N.I.13
Parsa, A.14
Ober, C.C.15
Welling, P.A.16
Chakravarti, A.17
Weder, A.B.18
Cooper, R.S.19
Mitchell, B.D.20
Shuldiner, A.R.21
Chang, Y.P.22
more..
-
29
-
-
17944373014
-
Human hypertension caused by mutations in WNK kinases
-
Wilson FH, Disse-Nicode'me S, Choate KA, Ishikawa K, Nelson- Williams C, Desitter I, Gunel M, Milford DV, Lipkin GW, Achard JM, Feely MP, Dussol B, Berland Y, Unwin RJ, Mayan H, Simon DB, Farfel Z, Jeunemaitre X, Lifton RP. Human hypertension caused by mutations in WNK kinases. Science 293: 1107-1112, 2001.
-
(2001)
Science
, vol.293
, pp. 1107-1112
-
-
Wilson, F.H.1
Disse-Nicode'me, S.2
Choate, K.A.3
Ishikawa, K.4
Nelson-Williams, C.5
Desitter, I.6
Gunel, M.7
Milford, D.V.8
Lipkin, G.W.9
Achard, J.M.10
Feely, M.P.11
Dussol, B.12
Berland, Y.13
Unwin, R.J.14
Mayan, H.15
Simon, D.B.16
Farfel, Z.17
Jeunemaitre, X.18
Lifton, R.P.19
-
30
-
-
78149310726
-
SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction
-
Yang SS, Lo YF, Wu CC, Lin SW, Yeh CJ, Chu P, Sytwu HK, Uchida S, Sasaki S, Lin SH. SPAK-knockout mice manifest Gitelman syndrome and impaired vasoconstriction. J Am Soc Nephrol 21: 1868-1877, 2010.
-
(2010)
J Am Soc Nephrol
, vol.21
, pp. 1868-1877
-
-
Yang, S.S.1
Lo, Y.F.2
Wu, C.C.3
Lin, S.W.4
Yeh, C.J.5
Chu, P.6
Sytwu, H.K.7
Uchida, S.8
Sasaki, S.9
Lin, S.H.10
-
31
-
-
34247617951
-
Molecular pathogenesis of pseudohypoaldosteronism type II: Generation and analysis of a Wnk4(D561A/+) knockin mouse model
-
Yang SS, Morimoto T, Rai T, Chiga M, Sohara E, Ohno M, Uchida K, Lin SH, Moriguchi T, Shibuya H, Kondo Y, Sasaki S, Uchida S. Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model. Cell Metab 5: 331-344, 2007.
-
(2007)
Cell Metab
, vol.5
, pp. 331-344
-
-
Yang, S.S.1
Morimoto, T.2
Rai, T.3
Chiga, M.4
Sohara, E.5
Ohno, M.6
Uchida, K.7
Lin, S.H.8
Moriguchi, T.9
Shibuya, H.10
Kondo, Y.11
Sasaki, S.12
Uchida, S.13
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