Tumor evolution and intratumor heterogeneity of an epithelial ovarian cancer investigated using next-generation sequencing

BMC Cancer

Volumn 15, Issue 1, 2015, Pages

  Lee, Jung Yun ^a   Yoon, Jung Ki ^a   Kim, Boyun ^b   Kim, Soochi ^b   Kim, Min A ^b   Lim, Hyeonseob ^c   Bang, Duhee ^c   Song, Yong Sang ^a,b  

^a Seoul National University   (South Korea)

^b Seoul National University College of Medicine   (South Korea)

^c Yonsei University   (South Korea)

Author keywords

High grade serous ovarian cancer; Intratumor heterogeneity; Peritoneal seeding; Transcoelomic metastasis; Whole exome sequencing

Indexed keywords

PLATINUM COMPLEX; PROTEIN P53;

AGED; ARTICLE; CANCER GRADING; CANCER GROWTH; CARCINOGENESIS; CASE REPORT; CONTROLLED STUDY; COPY NUMBER VARIATION; CYTOREDUCTIVE SURGERY; EXOME; FEMALE; GENE SEQUENCE; GENETIC CODE; GENETIC HETEROGENEITY; HUMAN; HUMAN TISSUE; INTRATUMOR HETEROGENEITY; METASTASIS; MOLECULAR EVOLUTION; NEXT GENERATION SEQUENCING; OVARY CARCINOMA; PHYLOGENETIC TREE; SOMATIC MUTATION; TUMOR SEEDING; TUMOR SUPPRESSOR GENE; BIOLOGICAL MODEL; CANCER STAGING; GENETICS; HIGH THROUGHPUT SEQUENCING; INDEL MUTATION; MUTATION; NEOPLASM; OVARY TUMOR; PATHOLOGY;

AGED; DNA COPY NUMBER VARIATIONS; EXOME; FEMALE; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INDEL MUTATION; MODELS, BIOLOGICAL; MUTATION; NEOPLASM GRADING; NEOPLASM METASTASIS; NEOPLASM STAGING; NEOPLASMS, GLANDULAR AND EPITHELIAL; OVARIAN NEOPLASMS;

EID: 84924048777     PISSN: None     EISSN: 14712407     Source Type: Journal    
DOI: 10.1186/s12885-015-1077-4     Document Type: Article

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