A longitudinal study of thyroid autoantibodies in pregnancy: The importance of test timing

Clinical Endocrinology

Volumn 82, Issue 4, 2015, Pages 604-610

  Ekinci, E I ^a,b,c   Chiu, W L ^a   Lu, Z X ^d,e   Sikaris, K ^d   Churilov, L ^f,g   Bittar, I ^a   Lam, Q ^a   Crinis, N ^a   Houlihan, Christine A ^a,h  

^a AUSTIN HEALTH   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c MENZIES SCHOOL OF HEALTH RESEARCH   (Australia)

^d Melbourne Pathology ^*  (Australia)

^e MONASH UNIVERSITY   (Australia)

^f FLOREY INSTITUTE OF NEUROSCIENCE AND MENTAL HEALTH   (Australia)

^g RMIT UNIVERSITY   (Australia)

^h MERCY HOSPITAL FOR WOMEN   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

THYROGLOBULIN ANTIBODY; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; AUTOANTIBODY; IODIDE PEROXIDASE; THYROGLOBULIN;

ADULT; ANTIBODY BLOOD LEVEL; ARTICLE; FEMALE; GESTATION PERIOD; HASHIMOTO DISEASE; HUMAN; IMMUNOASSAY; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MATERNAL DISEASE; OUTCOME ASSESSMENT; POST PARTUM THYROID DYSFUNCTION; PREDICTIVE VALUE; PREGNANCY; PRIORITY JOURNAL; PROSPECTIVE STUDY; PUERPERIUM; SCREENING TEST; THYROID DISEASE; THYROID FUNCTION; THYROTROPIN BLOOD LEVEL; BLOOD; CHEMISTRY; COMPLICATION; IMMUNOLOGY; PREGNANCY COMPLICATION; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; THYROID GLAND; TREATMENT OUTCOME;

ADULT; AUTOANTIBODIES; FEMALE; HASHIMOTO DISEASE; HUMANS; IODIDE PEROXIDASE; LONGITUDINAL STUDIES; POSTPARTUM PERIOD; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; THYROGLOBULIN; THYROID DISEASES; THYROID GLAND; TREATMENT OUTCOME;

EID: 84924025004     PISSN: 03000664     EISSN: 13652265     Source Type: Journal    
DOI: 10.1111/cen.12571     Document Type: Article

References (25)

1. Topliss, D.J., &, Eastman, C.J., (2004) 5: Diagnosis and management of hyperthyroidism and hypothyroidism. Medical Journal of Australia, 180, 186-193.
2. Hollowell, J.G., Staehling, N.W., Flanders, W.D., et al,. (2002) Serum TSH, T(4), and thyroid antibodies in the United States population (1988 to 1994): National Health and Nutrition Examination Survey (NHANES III). Journal of Clinical Endocrinology and Metabolism, 87, 489-499.
3. Stagnaro-Green, A., Roman, S.H., Cobin, R.H., et al,. (1990) Detection of at-risk pregnancy by means of highly sensitive assays for thyroid autoantibodies. JAMA, 264, 1422-1425.
4. Glinoer, D., Riahi, M., Grün, J.P., et al,. (1994) Risk of subclinical hypothyroidism in pregnant women with asymptomatic autoimmune thyroid disorders. Journal of Clinical Endocrinology and Metabolism, 79, 197-204.
5. Lazarus, J.H., (2011) Thyroid function in pregnancy. British Medical Bulletin, 97, 137-148.
6. Glinoer, D., (2004) The regulation of thyroid function during normal pregnancy: importance of the iodine nutrition status. Best Practice & Research. Clinical Endocrinology Metabolism, 18, 133-152.
7. Negro, R., Formoso, G., Mangieri, T., et al,. (2006) Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. Journal of Clinical Endocrinology and Metabolism, 91, 2587-2591.
8. Negro, R., Schwartz, A., Gismondi, R., et al,. (2010) Increased pregnancy loss rate in thyroid antibody negative women with TSH levels between 2.5 and 5.0 in the first trimester of pregnancy. Journal of Clinical Endocrinology and Metabolism, 95, E44-E48.
9. Abalovich, M., Gutierrez, S., Alcaraz, G., et al,. (2002) Overt and subclinical hypothyroidism complicating pregnancy. Thyroid, 12, 63-68.
10. Haddow, J.E., Palomaki, G.E., Allan, W.C., et al,. (1999) Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. New England Journal of Medicine, 341, 549-555.
11. Klein, R.Z., Sargent, J.D., Larsen, P.R., et al,. (2001) Relation of severity of maternal hypothyroidism to cognitive development of offspring. Journal of Medical Screening, 8, 18-20.
12. Smyth, P.P., Wijeyaratne, C.N., Kaluarachi, W.N., et al,. (2005) Sequential studies on thyroid antibodies during pregnancy. Thyroid, 15, 474-477.
13. Kuijpens, J.L., Pop, V.J., Vader, H.L., et al,. (1998) Prediction of post partum thyroid dysfunction: can it be improved? European Journal of Endocrinology, 139, 36-43.
14. Parker, R.H., &, Beierwaltes, W.H., (1961) Thyroid antibodies during pregnancy and in the newborn. Journal of Clinical Endocrinology and Metabolism, 21, 792-798.
15. Stagnaro-Green, A., Abalovich, M., Alexander, E., et al,. (2011) Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid, 21, 1081-1125.
16. De Groot, L., Abalovich, M., Alexander, E.K., et al,. (2012) Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. Journal of Clinical Endocrinology and Metabolism, 97, 2543-2565.
17. Ekinci, E.I., Lu, Z.X., Sikaris, K., et al,. (2013) Longitudinal assessment of thyroid function in pregnancy. Annals of Clinical Biochemistry, 50, 595-602.
18. Gaberscek, S., &, Zaletel, K., (2011) Thyroid physiology and autoimmunity in pregnancy and after delivery. Expert Review of Clinical Immunology, 7, 697-706; quiz 707.
19. Balucan, F.S., Morshed, S.A., &, Davies, T.F., (2013) Thyroid autoantibodies in pregnancy: their role, regulation and clinical relevance. Journal of Thyroid Research, 2013, 182472.
20. Stagnaro-Green, A., Roman, S.H., Cobin, R.H., et al,. (1992) A prospective study of lymphocyte-initiated immunosuppression in normal pregnancy: evidence of a T-cell etiology for postpartum thyroid dysfunction. Journal of Clinical Endocrinology and Metabolism, 74, 645-653.
21. Gonzalez, C., Hernando, M., Cava, F., et al,. (2002) Biological variability of thyroid autoantibodies (anti-TPO and anti-Tg) in clinically and biochemically stable patients with autoimmune thyroid disease. Journal of Clinical Laboratory Analysis, 16, 37-39.
22. Muller, A.F., Drexhage, H.A., &, Berghout, A., (2001) Postpartum thyroiditis and autoimmune thyroiditis in women of childbearing age: recent insights and consequences for antenatal and postnatal care. Endocrine Reviews, 22, 605-630.
23. Kent, G.N., Stuckey, B.G., Allen, J.R., et al,. (1999) Postpartum thyroid dysfunction: clinical assessment and relationship to psychiatric affective morbidity. Clinical Endocrinology, 51, 429-438.
24. Smallridge, R., (2000) Postpartum thyroid disease: a model of immunologic dysfunction. Clinical and Applied Immunology Reviews, 1, 89-103.
25. Amino, N., Kuro, R., Tanizawa, O., et al,. (1978) Changes of serum anti-thyroid antibodies during and after pregnancy in autoimmune thyroid diseases. Clinical and Experimental Immunology, 31, 30-37.