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Volumn 15, Issue 2, 2015, Pages 156-162

Role of microRNAs in allergic asthma: Present and future

Author keywords

allergy; asthma; microRNAs; noncoding RNAs

Indexed keywords

MICRORNA; BIOLOGICAL MARKER;

EID: 84923916654     PISSN: 15284050     EISSN: 14736322     Source Type: Journal    
DOI: 10.1097/ACI.0000000000000147     Document Type: Article
Times cited : (43)

References (44)
  • 1
    • 84903841167 scopus 로고    scopus 로고
    • Emerging role of microRNAs and long noncoding RNAs in respiratory disease
    • Review of ncRNAs in respiratory disease
    • Booton R, Lindsay MA. Emerging role of microRNAs and long noncoding RNAs in respiratory disease. Chest 2014; 146:193-204. Review of ncRNAs in respiratory disease.
    • (2014) Chest , vol.146 , pp. 193-204
    • Booton, R.1    Lindsay, M.A.2
  • 2
    • 0347444723 scopus 로고    scopus 로고
    • MicroRNAs: Genomics, biogenesis, mechanism, and function
    • Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004; 116:281-297.
    • (2004) Cell , vol.116 , pp. 281-297
    • Bartel, D.P.1
  • 3
  • 4
    • 84882911915 scopus 로고    scopus 로고
    • Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults
    • The reduced expression of exhaled miRNAs in asthma
    • Pinkerton M, Chinchilli V, Banta E, et al. Differential expression of microRNAs in exhaled breath condensates of patients with asthma, patients with chronic obstructive pulmonary disease, and healthy adults. J Allergy Clin Immunol 2013; 132:217-219. The reduced expression of exhaled miRNAs in asthma.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 217-219
    • Pinkerton, M.1    Chinchilli, V.2    Banta, E.3
  • 5
    • 84904527116 scopus 로고    scopus 로고
    • The potential mechanistic link between allergy and obesity development and infant formula feeding
    • Role of miR-155in postnatal immune regulation and atopy
    • Melnik B. The potential mechanistic link between allergy and obesity development and infant formula feeding. Allergy Asthma Clin Immunol 2014; 10:37. Role of miR-155in postnatal immune regulation and atopy.
    • (2014) Allergy Asthma Clin Immunol , vol.10 , pp. 37
    • Melnik, B.1
  • 6
    • 84899656541 scopus 로고    scopus 로고
    • MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung
    • Role of miR-155 in Th2-mediated eosinophilic inflammation
    • Malmhall C, Alawieh S, Lu Y, et al. MicroRNA-155 is essential for TH2-mediated allergen-induced eosinophilic inflammation in the lung. J Allergy Clin Immunol 2014; 133:1429-1438. Role of miR-155 in Th2-mediated eosinophilic inflammation.
    • (2014) J Allergy Clin Immunol , vol.133 , pp. 1429-1438
    • Malmhall, C.1    Alawieh, S.2    Lu, Y.3
  • 7
    • 84879147532 scopus 로고    scopus 로고
    • Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells
    • Regulation of IFN- g production in NK cells by miR-155
    • Trotta R, Chen L, Costinean S, et al. Overexpression of miR-155 causes expansion, arrest in terminal differentiation and functional activation of mouse natural killer cells. Blood 2013; 121:3126-3134. Regulation of IFN- g production in NK cells by miR-155.
    • (2013) Blood , vol.121 , pp. 3126-3134
    • Trotta, R.1    Chen, L.2    Costinean, S.3
  • 8
    • 84883162180 scopus 로고    scopus 로고
    • MicroRNA-mediated regulation of T helper cell differentiation and plasticity
    • Impact of miRNAs upon T-cell phenotype
    • Baumjohann D, Ansel KM. MicroRNA-mediated regulation of T helper cell differentiation and plasticity. Nat Rev Immunol 2013; 13:666-678. Impact of miRNAs upon T-cell phenotype.
    • (2013) Nat Rev Immunol , vol.13 , pp. 666-678
    • Baumjohann, D.1    Ansel, K.M.2
  • 9
    • 84901661841 scopus 로고    scopus 로고
    • Role of non-coding RNAs in maintaining primary airway smooth muscle cells
    • Differential expression of ncRNAs in primary ASM cells following mitogen stimulation and CS treatment
    • Perry M, Tsitsiou E, Austin P, et al. Role of non-coding RNAs in maintaining primary airway smooth muscle cells. Respir Res 2014; 15:58. Differential expression of ncRNAs in primary ASM cells following mitogen stimulation and CS treatment.
    • (2014) Respir Res , vol.15 , pp. 58
    • Perry, M.1    Tsitsiou, E.2    Austin, P.3
  • 10
    • 84875456392 scopus 로고    scopus 로고
    • MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells
    • Role of miR-375 in EoE
    • Bleck B, Grunig G, Chiu A, et al. MicroRNA-375 regulation of thymic stromal lymphopoietin by diesel exhaust particles and ambient particulate matter in human bronchial epithelial cells. J Immunol 2013; 190:3757-3763. Role of miR-375 in EoE.
    • (2013) J Immunol , vol.190 , pp. 3757-3763
    • Bleck, B.1    Grunig, G.2    Chiu, A.3
  • 11
    • 84921385713 scopus 로고    scopus 로고
    • Plasma miRNAs might be promising biomarkers of chronic obstructive pulmonary disease
    • [Epub ahead of print] miRNAs as biomarkers of COPD
    • Wang M, Huang Y, Liang Z, et al. Plasma miRNAs might be promising biomarkers of chronic obstructive pulmonary disease. Clin Respir J 2014. [Epub ahead of print] miRNAs as biomarkers of COPD.
    • (2014) Clin Respir J
    • Wang, M.1    Huang, Y.2    Liang, Z.3
  • 12
    • 84923897502 scopus 로고    scopus 로고
    • MicroRNA-570-3p regulates Human antigen R (HuR) and cytokine expression in airway epithelial cells
    • Exhaled miR-570-3p expression is inversely correlated with lung function
    • Roff AN, Craig TJ, August A, et al. MicroRNA-570-3p regulates Human antigen R (HuR) and cytokine expression in airway epithelial cells. Am J Clin Exp Immunol 2014; 3:68-83. Exhaled miR-570-3p expression is inversely correlated with lung function.
    • (2014) Am J Clin Exp Immunol , vol.3 , pp. 68-83
    • Roff, A.N.1    Craig, T.J.2    August, A.3
  • 13
    • 84891750914 scopus 로고    scopus 로고
    • Airway smooth muscle hyperproliferation is regulated by microRNA-221 in severe asthma
    • Targeting of miR-221 in asthmatic ASM cells can reverse proliferation and IL-6 release
    • Perry MM, Baker JE, Gibeon DS, et al. Airway smooth muscle hyperproliferation is regulated by microRNA-221 in severe asthma. Am J Respir Cell Mol Biol 2013; 50:7-17. Targeting of miR-221 in asthmatic ASM cells can reverse proliferation and IL-6 release.
    • (2013) Am J Respir Cell Mol Biol , vol.50 , pp. 7-17
    • Perry, M.M.1    Baker, J.E.2    Gibeon, D.S.3
  • 14
    • 84885464748 scopus 로고    scopus 로고
    • VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis
    • Intranasal delivery of miR-1 inhibits inflammatory responses in mouse models of asthma
    • Takyar S, Vasavada H, Zhang JG, et al. VEGF controls lung Th2 inflammation via the miR-1-Mpl (myeloproliferative leukemia virus oncogene)-P-selectin axis. J Exp Med 2013; 210:1993-2010. Intranasal delivery of miR-1 inhibits inflammatory responses in mouse models of asthma.
    • (2013) J Exp Med , vol.210 , pp. 1993-2010
    • Takyar, S.1    Vasavada, H.2    Zhang, J.G.3
  • 15
    • 84882869840 scopus 로고    scopus 로고
    • Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity
    • miR-150 delivery via nanovesicles to T cells in mice
    • Bryniarski K, Ptak W, Jayakumar A, et al. Antigen-specific, antibody-coated, exosome-like nanovesicles deliver suppressor T-cell microRNA-150 to effector T cells to inhibit contact sensitivity. J Allergy Clin Immunol 2013; 132:170-181. miR-150 delivery via nanovesicles to T cells in mice.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 170-181
    • Bryniarski, K.1    Ptak, W.2    Jayakumar, A.3
  • 16
    • 84866163789 scopus 로고    scopus 로고
    • Evolution of inflammatory diseases
    • Okin D, Medzhitov R. Evolution of inflammatory diseases. Curr Biol 2012; 22:R733-R740.
    • (2012) Curr Biol , vol.22 , pp. R733-R740
    • Okin, D.1    Medzhitov, R.2
  • 17
    • 0032777880 scopus 로고    scopus 로고
    • Cytokines in asthma
    • Chung KF, Barnes PJ. Cytokines in asthma. Thorax 1999; 54:825-857.
    • (1999) Thorax , vol.54 , pp. 825-857
    • Chung, K.F.1    Barnes, P.J.2
  • 18
    • 84922560090 scopus 로고    scopus 로고
    • Mechanisms of glucocorticoid action and insensitivity in airways disease
    • Review of glucocorticoid action in respiratory disease
    • Boardman C, Chachi L, Gavrila A, et al. Mechanisms of glucocorticoid action and insensitivity in airways disease. Pulm Pharmacol Ther 2014; 29:129-143. Review of glucocorticoid action in respiratory disease.
    • (2014) Pulm Pharmacol Ther , vol.29 , pp. 129-143
    • Boardman, C.1    Chachi, L.2    Gavrila, A.3
  • 19
    • 80052810971 scopus 로고    scopus 로고
    • Regulation and function of miRNA-21 in health and disease
    • Kumarswamy R, Volkmann I, Thum T. Regulation and function of miRNA-21 in health and disease. RNA Biol 2011; 8:706-713.
    • (2011) RNA Biol , vol.8 , pp. 706-713
    • Kumarswamy, R.1    Volkmann, I.2    Thum, T.3
  • 20
    • 84879693760 scopus 로고    scopus 로고
    • MicroRNA-155 as a therapeutic target for inflammatory diseases
    • Review of miR-155 and inflammation
    • Kanwal N, John P, Bhatti A. MicroRNA-155 as a therapeutic target for inflammatory diseases. Rheumatol Int 2013; 33:557-560. Review of miR-155 and inflammation.
    • (2013) Rheumatol Int , vol.33 , pp. 557-560
    • Kanwal, N.1    John, P.2    Bhatti, A.3
  • 21
    • 59149084697 scopus 로고    scopus 로고
    • Role of miRNA-146a in the regulation of the innate immune response and cancer
    • Williams AE, Perry MM, Moschos SA, et al. Role of miRNA-146a in the regulation of the innate immune response and cancer. Biochem Soc Trans 2008; 36:1211-1215.
    • (2008) Biochem Soc Trans , vol.36 , pp. 1211-1215
    • Williams, A.E.1    Perry, M.M.2    Moschos, S.A.3
  • 22
    • 84892498658 scopus 로고    scopus 로고
    • Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA
    • The use of miRNAs as biomarkers of disease
    • Woodruff G. Subtypes of asthma defined by epithelial cell expression of messenger RNA and microRNA. Annals ATS 2013; 10:S186-S189. The use of miRNAs as biomarkers of disease.
    • (2013) Annals ATS , vol.10 , pp. S186-S189
    • Woodruff, G.1
  • 23
    • 84904644906 scopus 로고    scopus 로고
    • Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility
    • Differential histone modification profiles in Th2 cells and the role of miRNAs
    • Seumois G, Chavez L, Gerasimova A, et al. Epigenomic analysis of primary human T cells reveals enhancers associated with TH2 memory cell differentiation and asthma susceptibility. Nat Immunol 2014; 15:777-788. Differential histone modification profiles in Th2 cells and the role of miRNAs.
    • (2014) Nat Immunol , vol.15 , pp. 777-788
    • Seumois, G.1    Chavez, L.2    Gerasimova, A.3
  • 24
    • 84882885522 scopus 로고    scopus 로고
    • Exosome-enclosed microRNAs in exhaled breath hold potential for biomarker discovery in patients with pulmonary diseases
    • Differential expression of exhaled miRNAs in asthmatic patients
    • Sinha A, Yadav AK, Chakraborty S, et al. Exosome-enclosed microRNAs in exhaled breath hold potential for biomarker discovery in patients with pulmonary diseases. J Allergy Clin Immunol 2013; 132:219-222. Differential expression of exhaled miRNAs in asthmatic patients.
    • (2013) J Allergy Clin Immunol , vol.132 , pp. 219-222
    • Sinha, A.1    Yadav, A.K.2    Chakraborty, S.3
  • 25
    • 84875227143 scopus 로고    scopus 로고
    • Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients
    • Differential expression of exosomal miRNAs in mild asthma
    • Levañnen B, Bhakta NR, Torregrosa Paredes P, et al. Altered microRNA profiles in bronchoalveolar lavage fluid exosomes in asthmatic patients. J Allergy Clin Immunol 2013; 131:894-903. Differential expression of exosomal miRNAs in mild asthma.
    • (2013) J Allergy Clin Immunol , vol.131 , pp. 894-903
    • Levañnen, B.1    Bhakta, N.R.2    Torregrosa Paredes, P.3
  • 26
    • 84902186191 scopus 로고    scopus 로고
    • Overexpression of microRNA-21 and microRNA-126 in the patients of bronchial asthma
    • Differential expression of miR-21 and miR-126 in IL-13 stimulated asthmatic epithelial cells
    • Wu XB, Wang MY, Zhu HY, et al. Overexpression of microRNA-21 and microRNA-126 in the patients of bronchial asthma. Int J Clin Exp Med 2014; 7:1307-1312. Differential expression of miR-21 and miR-126 in IL-13 stimulated asthmatic epithelial cells.
    • (2014) Int J Clin Exp Med , vol.7 , pp. 1307-1312
    • Wu, X.B.1    Wang, M.Y.2    Zhu, H.Y.3
  • 27
    • 84908366121 scopus 로고    scopus 로고
    • MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle
    • Anti-inflammatory action of miR-146a and miR-146b in ASM cells
    • Comer BS, Camoretti-Mercado B, Kogut PC, et al. MicroRNA-146a and microRNA-146b expression and anti-inflammatory function in human airway smooth muscle. Am J Physiol Lung Cell Mol Physiol 2014; 307:L727-L734. Anti-inflammatory action of miR-146a and miR-146b in ASM cells.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.307 , pp. L727-L734
    • Comer, B.S.1    Camoretti-Mercado, B.2    Kogut, P.C.3
  • 28
    • 84922635724 scopus 로고    scopus 로고
    • Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells
    • [Epub ahead of print] Increased expression of miR-155 in asthmatic ASM cells
    • Comer BS, Camoretti-Mercado B, Kogut PC, et al. Cyclooxygenase-2 and microRNA-155 expression are elevated in asthmatic airway smooth muscle cells. Am J Respir Cell Mol Biol 2014. [Epub ahead of print] Increased expression of miR-155 in asthmatic ASM cells.
    • (2014) Am J Respir Cell Mol Biol
    • Comer, B.S.1    Camoretti-Mercado, B.2    Kogut, P.C.3
  • 29
    • 84901044654 scopus 로고    scopus 로고
    • MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway
    • miR-10a is the highest expressed miRNA in ASM and can control cell proliferation
    • Hu R, Pan W, Fedulov AV, et al. MicroRNA-10a controls airway smooth muscle cell proliferation via direct targeting of the PI3 kinase pathway. FASEB J 2014; 28:2347-2357. miR-10a is the highest expressed miRNA in ASM and can control cell proliferation.
    • (2014) FASEB J , vol.28 , pp. 2347-2357
    • Hu, R.1    Pan, W.2    Fedulov, A.V.3
  • 30
    • 84893696845 scopus 로고    scopus 로고
    • Altered microRNA expression of nasal mucosa in long-term asthma and allergic rhinitis
    • Differential expression of miRNAs in nasal biopsies of asthmatic patients
    • Suojalehto H, Lindstrom I, Majuri ML, et al. Altered microRNA expression of nasal mucosa in long-term asthma and allergic rhinitis. Int Arch Allergy Immunol 2014; 163:168-178. Differential expression of miRNAs in nasal biopsies of asthmatic patients.
    • (2014) Int Arch Allergy Immunol , vol.163 , pp. 168-178
    • Suojalehto, H.1    Lindstrom, I.2    Majuri, M.L.3
  • 31
    • 84885354603 scopus 로고    scopus 로고
    • Extracellular microRNAs are dynamic nonvesicular biomarkers of muscle turnover
    • Extracellular miRNAs are biomarkers of skeletal muscle turnover
    • Roberts TC, Godfrey C, McClorey G, et al. Extracellular microRNAs are dynamic nonvesicular biomarkers of muscle turnover. Nucl Acids Res 2013; 41:9500-9513. Extracellular miRNAs are biomarkers of skeletal muscle turnover.
    • (2013) Nucl Acids Res , vol.41 , pp. 9500-9513
    • Roberts, T.C.1    Godfrey, C.2    McClorey, G.3
  • 32
    • 84902665815 scopus 로고    scopus 로고
    • Air toxics and epigenetic effects: Ozone altered microRNAs in the sputum of human subjects
    • Ozone increases miRNA expression in humans
    • Fry RCR. Air toxics and epigenetic effects: ozone altered microRNAs in the sputum of human subjects. Am J Physiol 2014; 306:L1129-L1137. Ozone increases miRNA expression in humans.
    • (2014) Am J Physiol , vol.306 , pp. L1129-L1137
    • Fry, R.C.R.1
  • 33
    • 84908095285 scopus 로고    scopus 로고
    • Protein and microRNA biomarkers from lavage, urine, and serum in military personnel evaluated for dyspnea
    • Changes in miRNA expression in serum, lavage fluid and urine correlated with FVC
    • Brown J, Brewer H, Nicora C, et al. Protein and microRNA biomarkers from lavage, urine, and serum in military personnel evaluated for dyspnea. BMC Med Genomics 2014; 7:58. Changes in miRNA expression in serum, lavage fluid and urine correlated with FVC.
    • (2014) BMC Med Genomics , vol.7 , pp. 58
    • Brown, J.1    Brewer, H.2    Nicora, C.3
  • 34
    • 84900535223 scopus 로고    scopus 로고
    • Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation
    • let-7g is decreased in expression in HDM-exposed mice, and manipulation of this miRNA can reverse HDM-induced SMA induction
    • van der Velden JL, Hoffman SM, Alcorn JF, et al. Absence of c-Jun NH2-terminal kinase 1 protects against house dust mite-induced pulmonary remodeling but not airway hyperresponsiveness and inflammation. Am J Physiol Lung Cell Mol Physiol 2014; 306:L866-L875. let-7g is decreased in expression in HDM-exposed mice, and manipulation of this miRNA can reverse HDM-induced SMA induction.
    • (2014) Am J Physiol Lung Cell Mol Physiol , vol.306 , pp. L866-L875
    • Van Der Velden, J.L.1    Hoffman, S.M.2    Alcorn, J.F.3
  • 35
    • 85040427584 scopus 로고    scopus 로고
    • A polymorphism in HLA-G modifies statin benefit in asthma
    • [Epub ahead of print] Asthmatic patients with a single nucleotide polymorphism in HLA-G have reduced exacerbations compared with normals
    • Naidoo D, Wu AC, Brilliant MH, et al. A polymorphism in HLA-G modifies statin benefit in asthma. Pharmacogenomics J 2014. [Epub ahead of print] Asthmatic patients with a single nucleotide polymorphism in HLA-G have reduced exacerbations compared with normals.
    • (2014) Pharmacogenomics J
    • Naidoo, D.1    Wu, A.C.2    Brilliant, M.H.3
  • 36
    • 84923897501 scopus 로고    scopus 로고
    • International European Respiratory Society/American Thoracic Society guidelines on severe asthma
    • Recent guidelines on severe asthma
    • Chung KF, Wenzel S. International European Respiratory Society/American Thoracic Society guidelines on severe asthma. Eur Respir J 2014; 44:1378-1379. Recent guidelines on severe asthma.
    • (2014) Eur Respir J , vol.44 , pp. 1378-1379
    • Chung, K.F.1    Wenzel, S.2
  • 37
    • 84863418151 scopus 로고    scopus 로고
    • Action and reaction: The biological response to siRNA and its delivery vehicles
    • Kanasty RL, Whitehead KA, Vegas AJ, Anderson DG. Action and reaction: the biological response to siRNA and its delivery vehicles. Mol Ther 2012; 20:513-524.
    • (2012) Mol Ther , vol.20 , pp. 513-524
    • Kanasty, R.L.1    Whitehead, K.A.2    Vegas, A.J.3    Anderson, D.G.4
  • 38
    • 84887101163 scopus 로고    scopus 로고
    • MicroRNAs and other noncoding RNAs as targets for anticancer drug development
    • Review of ncRNAs in cancer
    • Ling H, Fabbri M, Calin GA. MicroRNAs and other noncoding RNAs as targets for anticancer drug development. Nat Rev Drug Discov 2013; 12:847-865. Review of ncRNAs in cancer.
    • (2013) Nat Rev Drug Discov , vol.12 , pp. 847-865
    • Ling, H.1    Fabbri, M.2    Calin, G.A.3
  • 39
    • 84877258007 scopus 로고    scopus 로고
    • Treatment of HCV infection by targeting microRNA
    • miR-122 treatment of hepatitis C in human clinical trials
    • Janssen HLA, Reesink HW, Lawitz EJ, et al. Treatment of HCV infection by targeting microRNA. N Engl J Med 2013; 368:1685-1694. miR-122 treatment of hepatitis C in human clinical trials.
    • (2013) N Engl J Med , vol.368 , pp. 1685-1694
    • Janssen, H.L.A.1    Reesink, H.W.2    Lawitz, E.J.3
  • 40
    • 84894339791 scopus 로고    scopus 로고
    • Comparison of hepatic transcription profiles of locked ribonucleic acid antisense oligonucleotides: Evidence of distinct pathways contributing to nontarget mediated toxicity in mice
    • Nucleic acid modifications (including LNAs) affect mechanistic pathways and may impact upon toxicity
    • Kakiuchi-Kiyota S, Koza-Taylor PH, Mantena SR, et al. Comparison of hepatic transcription profiles of locked ribonucleic acid antisense oligonucleotides: evidence of distinct pathways contributing to nontarget mediated toxicity in mice. Toxicol Sci 2014; 138:234-248. Nucleic acid modifications (including LNAs) affect mechanistic pathways and may impact upon toxicity.
    • (2014) Toxicol Sci , vol.138 , pp. 234-248
    • Kakiuchi-Kiyota, S.1    Koza-Taylor, P.H.2    Mantena, S.R.3
  • 41
    • 84884252518 scopus 로고    scopus 로고
    • Improved performance of antimiRNA oligonucleotides using a novel non-nucleotide modifier
    • Attaching ZEN to an anti-miR improves binding affinity and has low cellular toxicity
    • Lennox KA, Owczarzy R, Thomas DM, et al. Improved performance of antimiRNA oligonucleotides using a novel non-nucleotide modifier. Mol Ther Nucleic Acids 2013; 2:e117. Attaching ZEN to an anti-miR improves binding affinity and has low cellular toxicity.
    • (2013) Mol Ther Nucleic Acids , vol.2 , pp. e117
    • Lennox, K.A.1    Owczarzy, R.2    Thomas, D.M.3
  • 42
    • 84880304273 scopus 로고    scopus 로고
    • Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape
    • Cellular uptake and release of exogenously administered miRNAs are extremely low (less than 2%)
    • Gilleron J, Querbes W, Zeigerer A, et al. Image-based analysis of lipid nanoparticle-mediated siRNA delivery, intracellular trafficking and endosomal escape. Nat Biotech 2013; 31:638-646. Cellular uptake and release of exogenously administered miRNAs are extremely low (less than 2%).
    • (2013) Nat Biotech , vol.31 , pp. 638-646
    • Gilleron, J.1    Querbes, W.2    Zeigerer, A.3
  • 43
    • 84884935709 scopus 로고    scopus 로고
    • Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors
    • Nanovesicle delivery of chemotherapeutics to tumours
    • Jang SC, Kim OY, Yoon CM, et al. Bioinspired exosome-mimetic nanovesicles for targeted delivery of chemotherapeutics to malignant tumors. ACS Nano 2013; 7:7698-7710. Nanovesicle delivery of chemotherapeutics to tumours.
    • (2013) ACS Nano , vol.7 , pp. 7698-7710
    • Jang, S.C.1    Kim, O.Y.2    Yoon, C.M.3
  • 44
    • 84877252350 scopus 로고    scopus 로고
    • From pseudo-ceRNAs to circ-ceRNAs: A tale of cross-talk and competition
    • Novel functions of miRNAs
    • Taulli R, Loretelli C, Pandolfi PP. From pseudo-ceRNAs to circ-ceRNAs: a tale of cross-talk and competition. Nat Struct Mol Biol 2013; 20:541-543. Novel functions of miRNAs.
    • (2013) Nat Struct Mol Biol , vol.20 , pp. 541-543
    • Taulli, R.1    Loretelli, C.2    Pandolfi, P.P.3


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