Inhibition of CaMKK2 reverses age-associated decline in bone mass

Bone

Volumn 75, Issue , 2015, Pages 120-127

  Pritchard, Zachary J ^a   Cary, Rachel L ^a   Yang, Chang ^b   Novack, Deborah V ^b   Voor, Michael J ^a,c   Sankar, Uma ^a,d  

^a University of Louisville School of Medicine   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c University of Louisville   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Bone volume; Ca2+ calmodulin (CaM) dependent protein kinase kinase 2; Microarchitecture; STO 609; Three point bending; Trabecular punch compression

Indexed keywords

ALIZARIN RED S; CALCEIN; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE KINASE 2; PROTEIN SERINE THREONINE KINASE INHIBITOR; STO 609; UNCLASSIFIED DRUG; BENZIMIDAZOLE DERIVATIVE; CAMKK2 PROTEIN, MOUSE; ENZYME INHIBITOR; NAPHTHALIMIDE DERIVATIVE;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE CHARACTERISTICS AND FUNCTIONS; BONE EXAMINATION; BONE MASS; BONE MICROARCHITECTURE; BONE MID SHAFT GEOMETRY; BONE PUNCH COMPRESSION TEST; BONE STRENGTH; BONE STRESS; CHEMICAL LABELING; COHORT ANALYSIS; CONTROLLED STUDY; CORTICAL BONE; CORTICAL THICKNESS (BONE); ENZYME INHIBITION; MALE; MICRO-COMPUTED TOMOGRAPHY; MORPHOMETRICS; MOUSE; NONHUMAN; OSSIFICATION; OSTEOLYSIS; THREE POINT BENDING TEST; TRABECULAR BONE; TREATMENT DURATION; ANIMAL; ANTAGONISTS AND INHIBITORS; BONE DEVELOPMENT; C57BL MOUSE; COMPRESSIVE STRENGTH; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; FEMUR; KNOCKOUT MOUSE; OSTEOPOROSIS; PATHOLOGY; RADIOGRAPHY;

ANIMALS; BENZIMIDAZOLES; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE KINASE; COMPRESSIVE STRENGTH; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FEMUR; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NAPHTHALIMIDES; OSTEOGENESIS; OSTEOPOROSIS; X-RAY MICROTOMOGRAPHY;

EID: 84923916645     PISSN: 87563282     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bone.2015.01.021     Document Type: Article

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