Nav1.5 channels can reach the plasma membrane through distinct N-glycosylation states

Biochimica et Biophysica Acta - General Subjects

Volumn 1850, Issue 6, 2015, Pages 1215-1223

  Mercier, Aurélie ^a   Clément, Romain ^a   Harnois, Thomas ^a,b   Bourmeyster, Nicolas ^a,b   Bois, Patrick ^a   Chatelier, Aurélien ^a  

^a UNIVERSITÉ DE POITIERS   (France)

^b POITIERS UNIVERSITY HOSPITAL   (France)

Author keywords

Brugada syndrome; N glycosylation; Nav1.5; Negative dominance; Secretory pathway; Voltage gated sodium channel

Indexed keywords

BREFELDIN A; SODIUM CHANNEL NAV1.5; SCN5A PROTEIN, HUMAN;

ARTICLE; BIOTINYLATION; BRUGADA SYNDROME; CELL MEMBRANE; CONTROLLED STUDY; DEGLYCOSYLATION; GLYCOSYLATION; HETEROZYGOSITY; HUMAN; HUMAN CELL; IMMUNOBLOTTING; PATCH CLAMP TECHNIQUE; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TRANSPORT; SIGNAL TRANSDUCTION; DRUG EFFECTS; GENETIC TRANSFECTION; GENETICS; HEK293 CELL LINE; MEMBRANE POTENTIAL; METABOLISM; MUTATION; PHENOTYPE; PROTEIN PROCESSING;

BREFELDIN A; CELL MEMBRANE; GLYCOSYLATION; HEK293 CELLS; HUMANS; MEMBRANE POTENTIALS; MUTATION; NAV1.5 VOLTAGE-GATED SODIUM CHANNEL; PHENOTYPE; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEIN TRANSPORT; TRANSFECTION;

EID: 84923912344     PISSN: 03044165     EISSN: 18728006     Source Type: Journal    
DOI: 10.1016/j.bbagen.2015.02.009     Document Type: Article

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