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Volumn 14, Issue 1, 2014, Pages

An open-label pilot trial of minocycline in children as a treatment for Angelman syndrome

Author keywords

Angelman syndrome; Ataxia; Autism; Cognitive impairment; Epilepsy; Seizure

Indexed keywords

MINOCYCLINE; ANTIINFECTIVE AGENT;

EID: 84923853737     PISSN: None     EISSN: 14712377     Source Type: Journal    
DOI: 10.1186/s12883-014-0232-x     Document Type: Article
Times cited : (49)

References (53)
  • 1
    • 84995191751 scopus 로고
    • 'Puppet' children a report on three cases
    • Angelman H: 'Puppet' children a report on three cases. Dev Med Child Neurol 1965, 7(6):681-688.
    • (1965) Dev Med Child Neurol , vol.7 , Issue.6 , pp. 681-688
    • Angelman, H.1
  • 2
    • 11244252216 scopus 로고    scopus 로고
    • Behavioral aspects of Angelman syndrome: a case control study
    • Barry RJ, Leitner RP, Clarke AR, Einfeld SL: Behavioral aspects of Angelman syndrome: a case control study. Am J Med Genet A 2005, 132A(1):8-12.
    • (2005) Am J Med Genet A , vol.132 A , Issue.1 , pp. 8-12
    • Barry, R.J.1    Leitner, R.P.2    Clarke, A.R.3    Einfeld, S.L.4
  • 3
    • 12744269033 scopus 로고    scopus 로고
    • Neurological aspects of the Angelman syndrome
    • Williams CA: Neurological aspects of the Angelman syndrome. Brain Dev 2005, 27(2):88-94.
    • (2005) Brain Dev , vol.27 , Issue.2 , pp. 88-94
    • Williams, C.A.1
  • 4
    • 33645929715 scopus 로고    scopus 로고
    • The behavioural phenotype of Angelman syndrome
    • Horsler K, Oliver C: The behavioural phenotype of Angelman syndrome. J Intellect Disabil Res 2006, 50(Pt 1):33-53.
    • (2006) J Intellect Disabil Res , vol.50 , pp. 33-53
    • Horsler, K.1    Oliver, C.2
  • 5
    • 78049395022 scopus 로고    scopus 로고
    • The behavioral phenotype of the Angelman syndrome
    • Williams CA: The behavioral phenotype of the Angelman syndrome. Am J Med Genet C: Semin Med Genet 2010, 154C(4):432-437.
    • (2010) Am J Med Genet C: Semin Med Genet , vol.154 C , Issue.4 , pp. 432-437
    • Williams, C.A.1
  • 6
    • 47849125828 scopus 로고    scopus 로고
    • Behavior and neuropsychiatric manifestations in Angelman syndrome
    • Pelc K, Cheron G, Dan B: Behavior and neuropsychiatric manifestations in Angelman syndrome. Neuropsychiatr Dis Treat 2008, 4(3):577.
    • (2008) Neuropsychiatr Dis Treat , vol.4 , Issue.3 , pp. 577
    • Pelc, K.1    Cheron, G.2    Dan, B.3
  • 7
    • 0037328861 scopus 로고    scopus 로고
    • Angelman syndrome: a review of the clinical and genetic aspects
    • Clayton-Smith J, Laan L: Angelman syndrome: a review of the clinical and genetic aspects. J Med Genet 2003, 40(2):87-95.
    • (2003) J Med Genet , vol.40 , Issue.2 , pp. 87-95
    • Clayton-Smith, J.1    Laan, L.2
  • 8
    • 0023925498 scopus 로고
    • The EEG in early diagnosis of the Angelman (happy puppet) syndrome
    • Boyd SG, Harden A, Patton MA: The EEG in early diagnosis of the Angelman (happy puppet) syndrome. Eur J Pediatr 1988, 147(5):508-513.
    • (1988) Eur J Pediatr , vol.147 , Issue.5 , pp. 508-513
    • Boyd, S.G.1    Harden, A.2    Patton, M.A.3
  • 10
    • 12744253284 scopus 로고    scopus 로고
    • Angelman syndrome: is there a characteristic EEG?
    • Laan LA, Vein AA: Angelman syndrome: is there a characteristic EEG? Brain Dev 2005, 27(2):80-87.
    • (2005) Brain Dev , vol.27 , Issue.2 , pp. 80-87
    • Laan, L.A.1    Vein, A.A.2
  • 12
    • 40049099239 scopus 로고    scopus 로고
    • Epilepsy in Angelman syndrome
    • Pelc K, Boyd SG, Cheron G, Dan B: Epilepsy in Angelman syndrome. Seizure 2008, 17(3):211-217.
    • (2008) Seizure , vol.17 , Issue.3 , pp. 211-217
    • Pelc, K.1    Boyd, S.G.2    Cheron, G.3    Dan, B.4
  • 13
    • 67949106580 scopus 로고    scopus 로고
    • Angelman syndrome scientific symposium on the structure and function of UBE3A/E6AP
    • Williams C: Angelman syndrome scientific symposium on the structure and function of UBE3A/E6AP. J Child Neurol 2009, 24(7):904-908.
    • (2009) J Child Neurol , vol.24 , Issue.7 , pp. 904-908
    • Williams, C.1
  • 14
    • 0031012849 scopus 로고    scopus 로고
    • UBE3A/E6-AP mutations cause Angelman syndrome
    • Kishino T, Lalande M, Wagstaff J: UBE3A/E6-AP mutations cause Angelman syndrome. Nat Genet 1997, 15(1):70-73.
    • (1997) Nat Genet , vol.15 , Issue.1 , pp. 70-73
    • Kishino, T.1    Lalande, M.2    Wagstaff, J.3
  • 16
    • 37549057995 scopus 로고    scopus 로고
    • The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology
    • Dindot SV, Antalffy BA, Bhattacharjee MB, Beaudet AL: The Angelman syndrome ubiquitin ligase localizes to the synapse and nucleus, and maternal deficiency results in abnormal dendritic spine morphology. Hum Mol Genet 2008, 17(1):111-118.
    • (2008) Hum Mol Genet , vol.17 , Issue.1 , pp. 111-118
    • Dindot, S.V.1    Antalffy, B.A.2    Bhattacharjee, M.B.3    Beaudet, A.L.4
  • 23
    • 62149089881 scopus 로고    scopus 로고
    • Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model
    • Bilousova TV, Dansie L, Ngo M, Aye J, Charles JR, Ethell DW, Ethell IM: Minocycline promotes dendritic spine maturation and improves behavioural performance in the fragile X mouse model. J Med Genet 2009, 46(2):94-102.
    • (2009) J Med Genet , vol.46 , Issue.2 , pp. 94-102
    • Bilousova, T.V.1    Dansie, L.2    Ngo, M.3    Aye, J.4    Charles, J.R.5    Ethell, D.W.6    Ethell, I.M.7
  • 24
    • 77956124441 scopus 로고    scopus 로고
    • Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2
    • Kernt M, Neubauer AS, Eibl KH, Wolf A, Ulbig MW, Kampik A, Hirneiss C: Minocycline is cytoprotective in human trabecular meshwork cells and optic nerve head astrocytes by increasing expression of XIAP, survivin, and Bcl-2. Clin Ophthalmol (Auckland, NZ) 2010, 4:591.
    • (2010) Clin Ophthalmol (Auckland, NZ) , vol.4 , pp. 591
    • Kernt, M.1    Neubauer, A.S.2    Eibl, K.H.3    Wolf, A.4    Ulbig, M.W.5    Kampik, A.6    Hirneiss, C.7
  • 25
    • 84906926249 scopus 로고    scopus 로고
    • Minocycline modulates cytokine and gene expression profiles in the brain after whole-body exposure to radiation
    • Mehrotra S, Pecaut MJ, Gridley DS: Minocycline modulates cytokine and gene expression profiles in the brain after whole-body exposure to radiation. In vivo 2014, 28(1):21-32.
    • (2014) In vivo , vol.28 , Issue.1 , pp. 21-32
    • Mehrotra, S.1    Pecaut, M.J.2    Gridley, D.S.3
  • 26
    • 1342289413 scopus 로고    scopus 로고
    • MAPK cascade signalling and synaptic plasticity
    • Thomas GM, Huganir RL: MAPK cascade signalling and synaptic plasticity. Nat Rev Neurosci 2004, 5(3):173-183.
    • (2004) Nat Rev Neurosci , vol.5 , Issue.3 , pp. 173-183
    • Thomas, G.M.1    Huganir, R.L.2
  • 27
    • 84862790394 scopus 로고    scopus 로고
    • The two different effects of the potential neuroprotective compound minocycline on AMPA-type glutamate receptors
    • Jin LJ, Schlesinger F, Guan Q, Song YP, Nie ZY: The two different effects of the potential neuroprotective compound minocycline on AMPA-type glutamate receptors. Pharmacology 2012, 89(3-4):156-162.
    • (2012) Pharmacology , vol.89 , Issue.3-4 , pp. 156-162
    • Jin, L.J.1    Schlesinger, F.2    Guan, Q.3    Song, Y.P.4    Nie, Z.Y.5
  • 28
    • 79954603474 scopus 로고    scopus 로고
    • Effects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient mice
    • Chen H, Manev H: Effects of minocycline on cocaine sensitization and phosphorylation of GluR1 receptors in 5-lipoxygenase deficient mice. Neuropharmacology 2011, 60(7-8):1058-1063.
    • (2011) Neuropharmacology , vol.60 , Issue.7-8 , pp. 1058-1063
    • Chen, H.1    Manev, H.2
  • 29
    • 70450163934 scopus 로고    scopus 로고
    • Interactions with GluR1 AMPA receptors could influence the therapeutic usefulness of minocycline in ALS
    • Manev H, Manev R: Interactions with GluR1 AMPA receptors could influence the therapeutic usefulness of minocycline in ALS. Amyotroph Lateral Scler 2009, 10(5-6):416-417.
    • (2009) Amyotroph Lateral Scler , vol.10 , Issue.5-6 , pp. 416-417
    • Manev, H.1    Manev, R.2
  • 30
    • 11844306024 scopus 로고    scopus 로고
    • In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-D-aspartate
    • Goni-Allo B, Ramos M, Jordán J, Aguirre N: In vivo studies on the protective role of minocycline against excitotoxicity caused by malonate or N-methyl-D-aspartate. Exp Neurol 2005, 191(2):326-330.
    • (2005) Exp Neurol , vol.191 , Issue.2 , pp. 326-330
    • Goni-Allo, B.1    Ramos, M.2    Jordán, J.3    Aguirre, N.4
  • 32
    • 38749139293 scopus 로고    scopus 로고
    • Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline
    • Fujita Y, Ishima T, Kunitachi S, Hagiwara H, Zhang L, Iyo M, Hashimoto K: Phencyclidine-induced cognitive deficits in mice are improved by subsequent subchronic administration of the antibiotic drug minocycline. Prog Neuro-Psychopharmacol Biol Psychiatry 2008, 32(2):336-339.
    • (2008) Prog Neuro-Psychopharmacol Biol Psychiatry , vol.32 , Issue.2 , pp. 336-339
    • Fujita, Y.1    Ishima, T.2    Kunitachi, S.3    Hagiwara, H.4    Zhang, L.5    Iyo, M.6    Hashimoto, K.7
  • 35
    • 0033359937 scopus 로고    scopus 로고
    • Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo
    • Quinlan EM, Philpot BD, Huganir RL, Bear MF: Rapid, experience-dependent expression of synaptic NMDA receptors in visual cortex in vivo. Nat Neurosci 1999, 2(4):352-357.
    • (1999) Nat Neurosci , vol.2 , Issue.4 , pp. 352-357
    • Quinlan, E.M.1    Philpot, B.D.2    Huganir, R.L.3    Bear, M.F.4
  • 39
    • 84870717922 scopus 로고    scopus 로고
    • Decreased tonic inhibition in cerebellar granule cells causes motor dysfunction in a mouse model of Angelman syndrome
    • 163ra157-163ra157
    • Egawa K, Kitagawa K, Inoue K, Takayama M, Takayama C, Saitoh S, Kishino T, Kitagawa M, Fukuda A: Decreased tonic inhibition in cerebellar granule cells causes motor dysfunction in a mouse model of Angelman syndrome. Sci Transl Med 2012, 4(163):163ra157-163ra157.
    • (2012) Sci Transl Med , vol.4 , Issue.163
    • Egawa, K.1    Kitagawa, K.2    Inoue, K.3    Takayama, M.4    Takayama, C.5    Saitoh, S.6    Kishino, T.7    Kitagawa, M.8    Fukuda, A.9
  • 40
    • 0029996508 scopus 로고    scopus 로고
    • Safety of long-term high-dose minocycline in the treatment of acne
    • Goulden V, Glass D, Cunliffe WJ: Safety of long-term high-dose minocycline in the treatment of acne. Br J Dermatol 1996, 134(4):693-695.
    • (1996) Br J Dermatol , vol.134 , Issue.4 , pp. 693-695
    • Goulden, V.1    Glass, D.2    Cunliffe, W.J.3
  • 44
    • 34447559058 scopus 로고    scopus 로고
    • Web
    • NINDS Common Data Elements. National Institutes of Health 2014, [ http://www.commondataelements.ninds.nih.gov/epilepsy.aspx#tab=Data_Standards ]. Web.
    • (2014) National Institutes of Health
  • 46
    • 0032362520 scopus 로고    scopus 로고
    • Use of bayley scales in individuals with profound mental retardation: comparison of the first and second editions
    • DeWitt M, Schreck K, Mulick J: Use of bayley scales in individuals with profound mental retardation: comparison of the first and second editions. J Dev Phys Disabil 1998, 10(3):307-313.
    • (1998) J Dev Phys Disabil , vol.10 , Issue.3 , pp. 307-313
    • DeWitt, M.1    Schreck, K.2    Mulick, J.3
  • 48
    • 84904470436 scopus 로고    scopus 로고
    • The STROBE statement and neuropsychology: lighting the way toward evidence-based practice
    • ahead-of-print.
    • Loring DW, Bowden SC: The STROBE statement and neuropsychology: lighting the way toward evidence-based practice. Clin Neuropsychol 2013, 1-19. ahead-of-print.
    • (2013) Clin Neuropsychol , pp. 1-19
    • Loring, D.W.1    Bowden, S.C.2
  • 49
    • 84923903285 scopus 로고    scopus 로고
    • 3rd Edition, to Assess Individuals with Severe Delays, Web
    • Pearson Education: Using the Bayley Scales of Infant and Toddler Development, 3rd Edition, to Assess Individuals with Severe Delays, 2008. [ http://images.pearsonassessments.com/images/tmrs/tmrs_rg/TechReport1.pdf?WT.mc_id=TMRS_Bayley_III_Technical_Report_1 ]. Web.
    • (2008)
  • 53
    • 57149129372 scopus 로고    scopus 로고
    • The clinical global impressions scale: applying a research tool in clinical practice
    • Busner J, Targum SD: The clinical global impressions scale: applying a research tool in clinical practice. Psychiatry 2007, 4(7):28-37.
    • (2007) Psychiatry , vol.4 , Issue.7 , pp. 28-37
    • Busner, J.1    Targum, S.D.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.