Autism-associated mutation inhibits protein kinase C-mediated neuroligin-4X enhancement of excitatory synapses

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 8, 2015, Pages 2551-2556

  Bemben, Michael A ^a,b   Nguyen, Quynh Anh ^c   Wang, Tongguang ^a   Lie, Yan ^a   Nicoll, Roger A ^c   Roche, Katherine W ^a  

^a NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Autism; Development; Neuroligin; Synaptic adhesion molecule; Synaptogenesis

Indexed keywords

NEUROLIGIN; NEUROLIGIN 4X; PROTEIN KINASE C; UNCLASSIFIED DRUG; MUTANT PROTEIN; NERVE CELL ADHESION MOLECULE; NLGN4X PROTEIN, HUMAN; PHOSPHOTHREONINE;

ANIMAL CELL; ARTICLE; AUTISM; GENE MUTATION; HUMAN; HUMAN CELL; NERVE CELL STIMULATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN POLYMORPHISM; PROTEIN PROCESSING; RAT; SYNAPSE; SYNAPTOGENESIS; AMINO ACID SEQUENCE; ANIMAL; CHEMISTRY; EXCITATORY POSTSYNAPTIC POTENTIAL; GENETICS; HEK293 CELL LINE; METABOLISM; MOLECULAR GENETICS; MUTATION; NERVE CELL; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

AMINO ACID SEQUENCE; ANIMALS; AUTISTIC DISORDER; CELL ADHESION MOLECULES, NEURONAL; EXCITATORY POSTSYNAPTIC POTENTIALS; HEK293 CELLS; HUMANS; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION; NEURONS; PHOSPHORYLATION; PHOSPHOTHREONINE; PROTEIN KINASE C; RATS, SPRAGUE-DAWLEY; SYNAPSES;

EID: 84923668371     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1500501112     Document Type: Article

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