Preparation of pH sensitive pluronic-docetaxel conjugate micelles to balance the stability and controlled release issues

Materials

Volumn 8, Issue 2, 2015, Pages 379-391

  Liang, Yanchao ^a   Su, Zhihui ^a   Yao, Yao ^a   Zhang, Na ^a  

^a SHANDONG UNIVERSITY   (China)

Author keywords

Conjugates; Docetaxel; Nano micelles; pH controlled release; Stability

Indexed keywords

CONVERGENCE OF NUMERICAL METHODS; CRITICAL MICELLE CONCENTRATION; DRUG DELIVERY; LIGHT SCATTERING; MICELLES; PARTICLE SIZE; PH SENSORS; TRANSMISSION ELECTRON MICROSCOPY;

AMPHIPHILIC PROPERTY; CONJUGATES; CONTROLLED RELEASE; DOCETAXEL; HYDRAZONE BONDS; NANOMICELLES; PH-CONTROLLED RELEASE; SPHERICAL MORPHOLOGIES;

DRUG PRODUCTS;

EID: 84923643714     PISSN: None     EISSN: 19961944     Source Type: Journal    
DOI: 10.3390/ma8020379     Document Type: Article

References (26)

1. Rodriguez, L.C.; Chari, J.; Aghyarian, S.; Gindri, I.M.; Kosmopoulos, V.; Rodrigues, D.C. Preparation and characterization of injectable brushite filled-poly (methyl methacrylate) bone cement. Materials 2014, 7, 6779-6795.
2. + T cell responses. J. Controll. Release 2014, 191, 24-33.
3. Wang, Y.; Chen, L.; Tan, L.; Zhao, Q.; Luo, F.; Wei, Y.; Qian, Z. PEG-PCL based micelle hydrogels as oral docetaxel delivery systems for breast cancer therapy. Biomaterials 2014, 35, 6972-6985.
4. Zhang, X.; Dong, Y.; Zeng, X.; Liang, X.; Li, X.; Tao, W.; Chen, H.; Jiang, Y.; Mei, L.; Feng, S.-S. The effect of autophagy inhibitors on drug delivery using biodegradable polymer nanoparticles in cancer treatment. Biomaterials 2014, 35, 1932-1943.
5. Chen, W.; Zhang, J.Z.; Hu, J.; Guo, Q.; Yang, D. Preparation of amphiphilic copolymers for covalent loading of paclitaxel for drug delivery system. J. Polym. Sci. A Polym. Chem. 2014, 52, 366-374.
6. Ke, X.; Ng, V.W.L.; Ono, R.J.; Chan, J.M.; Krishnamurthy, S.; Wang, Y.; Hedrick, J.L.; Yang, Y.Y. Role of non-covalent and covalent interactions in cargo loading capacity and stability of polymeric micelles. J. Controll. Release 2014, 193, 9-26.
7. Cabral, H.; Kataoka, K. Progress of drug-loaded polymeric micelles into clinical studies. J. Controll. Release 2014, 190, 465-476.
8. Sun, Q.; Radosz, M.; Shen, Y. Challenges in design of translational nanocarriers. J. Controll. Release 2012, 164, 156-169.
9. Kopeček, J. Polymer-drug conjugates: Origins, progress to date and future directions. Adv. Drug Deliv. Rev. 2013, 65, 49-59.
10. Deng, C.; Jiang, Y.; Cheng, R.; Meng, F.; Zhong, Z. Biodegradable polymeric micelles for targeted and controlled anticancer drug delivery: Promises, progress and prospects. Nano Today 2012, 7, 467-480.
11. Hoffman, A.S. Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation. Adv. Drug Deliv. Rev. 2013, 65, 10-16.
12. Gao, G.H.; Li, Y.; Lee, D.S. Environmental pH-sensitive polymeric micelles for cancer diagnosis and targeted therapy. J. Controll. Release 2013, 169, 180-184.
13. Quader, S.; Cabral, H.; Mochida, Y.; Ishii, T.; Liu, X.; Toh, K.; Kinoh, H.; Miura, Y.; Nishiyama, N.; Kataoka, K. Selective intracellular delivery of proteasome inhibitors through pH-sensitive polymeric micelles directed to efficient antitumor therapy. J. Controll. Release 2014, 188, 67-77.
14. Nakamura, H.; Etrych, T.; Chytil, P.; Ohkubo, M.; Fang, J.; Ulbrich, K.; Maeda, H. Two step mechanisms of tumor selective delivery of N-(2-hydroxypropyl) methacrylamide copolymer conjugated with pirarubicin via an acid-cleavable linkage. J. Controll. Release 2014, 174, 81-87.
15. Li, L.; Yang, Q.; Zhou, Z.; Zhong, J.; Huang, Y. Doxorubicin-loaded, charge reversible, folate modified HPMA copolymer conjugates for active cancer cell targeting. Biomaterials 2014, 35, 5171-5187.
16. Elsadek, B.; Graeser, R.; Warnecke, A.; Unger, C.; Saleem, T.; El-Melegy, N.; Madkor, H.; Kratz, F. Optimization of an albumin-binding prodrug of doxorubicin that is cleaved by prostate-specific antigen. ACS Med. Chem. Lett. 2010, 1, 234-238.
17. Kratz, F. INNO-206 (DOXO-EMCH), an albumin-binding prodrug of doxorubicin under development for phase II studies. Curr. Bioact. Comp. 2011, 7, 33-38.
18. Graeser, R.; Esser, N.; Unger, H.; Fichtner, I.; Zhu, A.; Unger, C.; Kratz, F. INNO-206, the (6-maleimidocaproyl hydrazone derivative of doxorubicin), shows superior antitumor efficacy compared to doxorubicin in different tumor xenograft models and in an orthotopic pancreas carcinoma model. Investig. New Drugs 2010, 28, 14-19.
19. Zhao, P.; Astruc, D. Docetaxel nanotechnology in anticancer therapy. ChemMedChem 2012, 7, 952-972.
20. Etrych, T.S.; Šírová, M.; Starovoytova, L.; Říhová, B.; Ulbrich, K. HPMA copolymer conjugates of paclitaxel and docetaxel with pH-controlled drug release. Mol. Pharm. 2010, 7, 1015-1026.
21. Journo-Gershfeld, G.; Kapp, D.; Shamay, Y.; Kopeček, J.; David, A. Hyaluronan oligomers-HPMA copolymer conjugates for targeting paclitaxel to CD44-overexpressing ovarian carcinoma. Pharm. Res. 2012, 29, 1121-1133.
22. Alani, A.W.; Bae, Y.; Rao, D.A.; Kwon, G.S. Polymeric micelles for the pH-dependent controlled, continuous low dose release of paclitaxel. Biomaterials 2010, 31, 1765-1772.
23. Liu, F.; Li, M.; Liu, C.; Liu, Y.; Liang, Y.; Wang, F.; Zhang, N. Tumor-specific delivery and therapy by double-targeted DTX-CMCS-PEG-NGR conjugates. Pharm. Res. 2014, 31, 475-488.
24. Liu, Z.; Wang, Y.; Zhang, J.; Li, M.; Liu, Y.; Zhang, N. Pluronic P123-docetaxel conjugate micelles: Synthesis, characterization, and antitumor activity. J. Biomed. Nanotechnol. 2013, 9, 2007-2016.
25. Wu, L.; Zhang, J.; Watanabe, W. Physical and chemical stability of drug nanoparticles. Adv. Drug Deliv. Rev. 2011, 63, 456-469.
26. Liu, F.; Feng, L.; Zhang, L.; Zhang, X.; Zhang, N. Synthesis, characterization and antitumor evaluation of CMCS-DTX conjugates as novel delivery platform for docetaxel. Int. J. Pharm. 2013, 451, 41-49.